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"Ertürk, Nergis"
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Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean
Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section (CS) on isthmocele formation.
Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation.
Results: Of the 106 patients, 31 (29.2%) were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele (42.58 ± 8.77 vs. 38.42 ± 9.50 minutes, p = 0.03). The neutrophil-to-lymphocyte ratio (NLR) was higher and platelet-to-lymphocyte ratio (PLR) was lower in the isthmocele group (p < 0.001). Logistic regression analysis revealed that, NLR (OR [odds ratio]: 0.23, 95% CI [confidence interval]: 0.117- 0.473, p < 0.001) and PLR (OR: 1.05, 95% CI: 1.027-1.078, p < 0.001) were identified as independent predictors for isthmocele formation after planned CS.
Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.
Journal Article
Effects of intrauterine devices on female sexual function: a cross-sectional study
Objectives: To examine the differences in sexual functions between women using copper intrauterine device (Cu-IUD) and levonorgestrel intrauterine system (LND-IUS).
Methods: A total of 125 women between the ages of 20 and 40 were included in the study. The demographic data of all participants were recorded. Female Sexual Function Index (FSFI) was performed to all participants. Study participants were divided into 3 groups; 42 Cu-IUD users, 42 LND-IUS users, and 41 control (not use contraceptive) group, then compared. Women with a total score lower than ≤ 26.5 were considered as having sexual dysfunction.
Results: The prevalence of female sexual dysfunction (FSD) was 56.8% among the participants. The total FSFI scores of Cu-IUD and LNG-IUS groups were similar. Moreover, the FSFI score of both IUD users was lower than the control group, and the difference was statistically significant (p < 0.001). The presence of Cu-IUD affected arousal more than pain, satisfaction, lubrication and orgasm scores (p = 0.016). Pain score was similar among IUD groups and significantly lower than controls (p < 0.001). Moreover, orgasm and satisfaction scores were found to be significantly higher in the control group than in the both IUD groups (p < 0.001). All of three groups were also similar about desire and lubrication domains of FSFI.
Conclusions: In conclusion, this study found that Cu-IUD and LNG-IUS users did not differ in terms of sexual function according to scores calculated by FSFI.
Journal Article
The relation of first trimester PaPP-A level and vaginal birth complications in large for gestational age fetuses
Aim: To investigate the association of vaginal birth complications with first trimester pregnancy associated plasma protein A (PaPP-A) level in LGA vaginal deliveries of non-diabetic mothers.
Methods: This is a retrospective study conducted in a tertiary hospital between May 2020 and July 2022. A total of 9,184 singleton pregnancies with normal vaginal delivery between 37 and 42 weeks were reviewed. Non- diabetic patients who gave birth to LGA infants were grouped according to the presence of vaginal birth complications and compared in terms of first trimester aneuploidy screening results. Regression analysis was used to investigate the effect of variables on complications. Receiver operating characteristic (ROC) analysis was performed for the threshold PaPP-A value to predict birth complications.
Results: Of the 357 patients, 68 (19.0%) had at least one complication, remaining 289 (81.0%) had no complications. First trimester serum PaPP-A level was significantly higher in complicated group than patients without complications (20.85 ± 19.73 vs 15.18 ± 15.81, p= 0.046). First trimester NT, β-hCG and PaPP-A are significantly associated with perinatal complications in LGA vaginal deliveries. The cut-off value of first trimester PaPP-A level was 10.46 mIU/mL to predict the complications with a sensitivity of 54.4% and a specificity of 54.3%.
Conclusions: First trimester PaPP-A level may be associated with vaginal birth complications in LGA infants from non-diabetic mothers.
Journal Article
Modernity and Its Fallen Languages: Tanpınar's \Hasret\, Benjamin's Melancholy
A comparative study of the politics and theory of language in the writings of Ahmet Hamdi Tanpınar and Walter Benjamin, this article suggests that a rethinking of the discursive commensurability and incommensurability of modern Turkish language and literature with western European representational practices has crucial implications for critical comparative methodology today. I leave behind conventional accounts based on models of European literary influence, emphasizing instead changes in writing practices that accompanied the development of modern literature and comparatism. Of particular significance for my analysis are the intensification of print culture and language reforms. I examine Tanpınar's writings as a special archive registering the problematic of representational writing, while exploring their continuities and discontinuities with Benjamin's work. I configure an alternative critical comparative framework, troubling the uneven epistemological categories of modernity through which \"East\" and \"West\" continue to structure even the transnationalist critical discourse that interrogates them.
Journal Article
Surrealism and Turkish Script Arts
While one tendency among scholars and critics working on the edge of the field is to re-read from modernism not only the \"international,\" but the full-blown global travel of modernist aesthetic forms and movements, another is to turn (or return) to the study of literatures in their particularized locality, continuing a critique of the parochialism of canonical Europeanist modernism and modernist studies. Türklerde Yazi Sanati (\"Turkish Script Arts\"; 1958), I will suggest here, maps a complexly refracted intersection of Western European and Turkish literary histories, one which we might think as exemplary in its very frustration of the exemplarity on which comparison, very conventionally, depends.5 A \"socio-psychological essay on the graphology and the aesthetics of Turkish script arts,\" to take the work's subtitle, Baltacioglu's book-length essay contrasts \"Turkish Islamic writing\" with the geometric abstraction of Latin letters, proposing a comparative anatomy of the two Turkish alphabets used during the twentieth century.
Journal Article
Those Outside the Scene: \Snow\ in the World Republic of Letters
Described by the author as \"my first and last political novel,\" Snow is, in what I will suggest are crucial ways, a novel less \"about\" Turkey than about the representation of Turkey on both a literary and a political world stage-\"the microcosm of Turkey in a small town\" inverted and expanded within a global world-literary and worldliterary- critical aesthetic.5 My argument will be that any reading of Snow properly sensitive to its author's investments in a transnational literary market must grapple with the novel's internal projective figuration of transnational readership, and that such a reading necessarily brings with it a sense of the real limits-which is not to say the impossibility, or the disvalue-of critical discourse on world literature.6 In thus focusing a literary-critical problematic of representation in and through Snow, my goal is to dislodge for a moment, from the doors of critical perception, the legacy of Pascale Casanova's now widely influential La république mondiale des lettres.
Journal Article
The risk of developing gestational diabetes mellitus in maternal subclinical hypothyroidism: a systematic review and meta-analysis
Purpose
The purpose of this study was to determine the association between maternal subclinical hypothyroidism (SCH) and gestational diabetes mellitus (GDM) risk.
Methods
This study is a systematic review and meta-analysis. Following PubMed, Medline, Scopus, Web of Science, and Google Scholar database search up to April 1 2021, a total of 4597 studies were identified. Studies published in English, with full text available, related to subclinical hypothyroidism in pregnancy, reporting or mentioning the incidence of GDM were included in the analysis. Following exclusion of studies, a total of 16 clinical trial were analyzed. For the risk of GDM, odds ratios (ORs) were calculated. Subgroup analyzes were performed according to gestational age and thyroid antibodies.
Results
Pregnant women with SCH were at increased risk of GDM compared to women with euthyroidism, overall (OR = 1.339, 95% CI 1.041–1.724;
p =
0.023). Additionally, SCH without thyroid antibodies has no significant effect on GDM risk (OR = 1.173, 95% CI 0.88–1.56;
p =
0.277) and pregnant women with SCH in the first trimester were not found to be at increased risk of GDM compared to women with euthyroidism regardless of thyroid antibodies (OR = 1.088, 95%CI 0.816–1.451;
p =
0.564).
Conclusions
Maternal SCH in pregnancy is related to an increased risk of GDM.
Journal Article
Modernity and Its Fallen Languages: Tanpιnar's Hasret, Benjamin's Melancholy
A comparative study of the politics and theory of language in the writings of Ahmet Hamdi Tanpιnar and Walter Benjamin, this article suggests that a rethinking of the discursive commensurability and incommensurability of modern Turkish language and literature with western European representational practices has crucial implications for critical comparative methodology today. I leave behind conventional accounts based on models of European literary influence, emphasizing instead changes in writing practices that accompanied the development of modern literature and comparatism. Of particular significance for my analysis are the intensification of print culture and language reforms. I examine Tanpιnar's writings as a special archive registering the problematic of representational writing, while exploring their continuities and discontinuities with Benjamin's work. I configure an alternative critical comparative framework, troubling the uneven epistemological categories of modernity through which “East” and “West” continue to structure even the transnationalist critical discourse that interrogates them.
Journal Article
The comparison of maternal and neonatal outcomes between emergency and planned cesarean deliveries in women with placenta previa
Objectives: To compare maternal and neonatal outcomes concerning emergency or planned cesarean deliveries in pregnancies complicated by placenta previa (PP), and to evaluate factors related to blood transfusion requirement.
Methods: Three hundred sixty-three women with PP with (n = 80) and without (n = 283) placenta accreta spectrum (PAS) who delivered between May 2016 and May 2021 were retrospectively reviewed. The patients were allocated to two main groups as PAS and non-PAS and into two subgroups as emergency cesarean delivery (ECD) and planned cesarean delivery (PCD).
Results: One hundred twenty-eight deliveries were emergency and 155 were planned in non-PAS group. In PAS group 38 patients were delivered urgently and 42 were delivered as planned. General anesthesia was preferred more frequently in emergency cases. Gestational age, birth weight, and the 1st and 5th minute APGAR scores of the infants were significantly lower and neonatal intensive care unit (ICU) admission was significantly higher in the ECD cases (p < 0.001) in both PAS and non-PAS groups. The total amount of blood and blood product transfused (p = 0.005), length of hospital stay (p = 0.022) were higher in the ECD cases and adult ICU admission was significantly higher in the ECD cases in non-PAS group (p = 0.016). In multilinear regression analysis, the need for blood transfusion was found to increase with the number of previous cesarean sections, ECD, PP with PAS, general anesthesia, and uterine artery ligation.
Conclusions: In placenta previa, which is an obstetric condition associated with serious maternal and neonatal morbidity and mortality, adverse maternal and neonatal outcomes increase in cases of emergency cesarean delivery.
Journal Article