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Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma originating from fibroblasts in the dermal connective tissue, comprising approximately 1% of all soft tissue sarcomas. While most cases involve the trunk and extremities, only 10%–15% occur in the cephalic region, representing less than 1% of all head and neck neoplasms. DFSP is notable for its high propensity for local recurrence following surgical excision and its low metastatic potential. We report a case of recurrent DFSP of the forehead extending to the anterior wall of the left frontal sinus, without brain involvement, in a 33‐year‐old male with a history of three prior wide local excisions. A multidisciplinary cancer team recommended systemic imatinib therapy. This case highlights the challenges of managing DFSP in an uncommon location, underscoring the importance of a multidisciplinary approach in addressing recurrent and complex presentations.

Multiple primary malignant neoplasms (MPMNs) are defined as two or more distinct tumors in the same individual. Synchronous breast and colon cancers are infrequent and present management challenges due to the lack of standardized guidelines. We report a 73‐year‐old woman presenting with a right breast mass, subsequently diagnosed as Grade 2 invasive ductal carcinoma. Staging CT incidentally revealed right colon wall thickening, and colonoscopy with biopsy confirmed moderately differentiated invasive adenocarcinoma. Following neoadjuvant chemotherapy, she underwent simultaneous radical mastectomy with axillary lymph node dissection and right hemicolectomy. Postoperative recovery was uneventful. Adjuvant chemoradiation was administered per multidisciplinary team (MDT) recommendation. Synchronous breast and colon cancers pose unique diagnostic and treatment planning challenges. MDT collaboration is crucial for personalized treatment strategies and optimized outcomes in these complex cases.

Post‐traumatic diaphragmatic hernia (PTDH) is defined as the migration of intra‐abdominal organs into the chest through a pathological defect in the diaphragm caused by trauma. PTDH is a rare condition, occurring in 3%–7% of all thoracoabdominal injuries. Approximately 14.6% of PTDH cases present months to years after the initial trauma. Cases of delayed PTDH complicated by bowel obstruction and perforation are exceedingly uncommon, with a reported prevalence of 0.17%–6%. In Africa, fewer than 10 cases of delayed PTDH have been documented over the past three decades. Despite the availability of published reports, there are no established practice guidelines for managing PTDH. Here, we present a case of delayed PTDH that manifested as acute bowel obstruction 12 years after a gunshot wound to the chest. The condition led to a fatal postoperative outcome. This case highlights the critical need for clinicians to consider PTDH in patients with a history of trauma presenting with acute bowel obstruction and underscores the importance of urgent surgical management to prevent fatal complications.

Background/Objectives: Triple-negative breast cancer (TNBC) is an aggressive subtype associated with a poor prognosis and limited treatment options. Inflammatory and hematological biomarkers have emerged as potential tools for disease characterization, particularly in low-resource settings. Methods: This cross-sectional analytical study was conducted between July 2022 and February 2024 at Dalal Jamm Hospital in Dakar, Senegal, and included 120 women: 40 with TNBC, 40 with hormone-dependent breast cancer (HDBC), and 40 healthy controls. Blood samples were collected at diagnosis before any treatment to measure complete blood counts and C-reactive protein (CRP) levels. Inflammatory ratios—neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR)—were calculated. Results: TNBC patients displayed a distinct inflammatory profile characterized by elevated neutrophil counts, CRP, NLR, and MLR, as well as reduced lymphocyte and basophil percentages compared to healthy controls. NLR > 1.12 demonstrated strong discriminatory ability (AUC = 0.847; sensitivity 90%; specificity 65%). Differences between TNBC and HDBC were less pronounced, except for CRP and basophil levels. Multivariate analysis confirmed independent associations of elevated NLR, CRP, and neutrophils with TNBC. Conclusions: These findings provide new insights into the inflammatory and hematological characteristics of TNBC in this population and support further investigation of accessible biomarkers for early disease stratification in similar settings.