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Learn more about the African-American culture with these ten easy-to-do crafts. Also, while you do these crafts read about famous African Americans.

From there I went to Paramount Pictures where I held the same title and subsequently went on to roles at Romley Davies Publicity, Lionsgate UK, in-house at the Tribeca Festival and Sundance Film Festival, and most recently I was PR manager, BFI Festivals, working across the BFI London Film Festival and BFI Flare: London LGBTQIA+ Film Festival. Complacency is sinister I can count on one hand the people who consistently hire me as a freelancer, giving me the opportunity to make a living for myself in professional environments where I am not subjected to biased and, in some situations, racist behaviours and language. Real and lasting change will not take place overnight, but what could begin to increase diversity and shift representation would be for more companies to aspire to achieve more non-white representation across all levels and roles, from assistants to the boardroom, and to find ways to hold themselves accountable.

\"From weavings to pinatas to pottery, these fun, easy crafts introduce you to the vibrant and diverse world of Latino cultures.\"--Provided by publisher.

An effective primary treatment for obsessive-compulsive disorder (OCD) in children and adolescents as well as adults is exposure and response prevention (ERP), a form of intervention in the context of cognitive-behavioral therapy. Despite strong evidence supporting the efficacy and effectiveness of ERP from studies in research and real-world settings, its clinical use remains limited. This underuse is often attributed to access barriers such as the scarcity of properly trained therapists, geographical constraints, and costs. Some of these barriers may be addressed with virtual behavioral health, providing ERP for OCD through video teletherapy and supplemented by app-based therapeutic tools and messaging support between sessions. Studies of teletherapy ERP in adults with OCD have shown benefits in research and real-world settings in both small and large samples. However, studies of teletherapy ERP in children and adolescents thus far have been in small samples and limited to research rather than real-world settings. This study reports on the real-world effectiveness of teletherapy ERP for OCD in the largest sample (N=2173) of child and adolescent patients to date. Children and adolescents with OCD were treated with live, face-to-face video teletherapy sessions, with parent or caregiver involvement, using ERP. Assessments were conducted at baseline, after 7-11 weeks, and after 13-17 weeks. Additionally, longitudinal assessments of OCD symptoms were performed at weeks 18-30, 31-42, and 43-54. We analyzed longitudinal outcomes of OCD symptoms, depression, anxiety, and stress using linear mixed models. Treatment resulted in a median 38.46% (IQR 12.50%-64.00%) decrease in OCD symptoms at 13-17 weeks, and 53.4% of youth met full response criteria at this point. Improvements were observed in all categories of starting symptom severity: mild (median 40.3%, IQR 8.5%-79.8%), moderate (median 38.4%, IQR 13.3%-63.6%), and severe (median 34.1%, IQR 6.6%-58.5%). In addition, there were significant reductions in the severity of depression, anxiety, and stress symptoms. The median amount of therapist involvement was 13 (IQR 10.0-16.0) appointments and 11.5 (IQR 9.0-15.0) hours. Further, symptom improvements were maintained or improved upon in the longitudinal assessment periods of weeks 18-30, 31-42, and 43-54. These results show that remote ERP treatment, assisted by technology, can effectively improve both core OCD and related depression, anxiety, and stress symptoms in children and adolescents with OCD in a real-world setting. Notable outcomes were achieved in a relatively small amount of therapist time, demonstrating its efficiency. Demonstrating the usefulness of a delivery format that overcomes several traditional barriers to treatment, these findings have implications for widespread dissemination of accessible, evidence-based care for children and adolescents with OCD.

Diverting loop ileostomy is performed after colectomy to allow for anastomotic healing, and prevention of pelvic sepsis when an anastomotic leak occurs. There is no consensus on the optimal timing of ileostomy closure, and there is limited data on complications associated with ileostomy closure greater than 12 months after creation. The aim of this study is to investigate outcomes of delayed loop ileostomy closure greater than 12 months after creation. Patients undergoing loop ileostomy closure between 2013 and 2023 at Carilion Medical Center, in Roanoke, VA were reviewed. Cohorts compared were defined as Control Group (closure < 4 months) and Delayed Group (closure > 12 months). Demographics and outcomes were compared. Statistical comparisons were performed using either Wilcoxon rank sum test, Pearson’s Chi-squared test or Fisher’s exact test. Statistical modeling included binary logistic regression for 30-day readmissions and a generalized linear modeling for days till bowel function returns. Adjusted odds ratios, confidence intervals, and p-values were calculated. There were 135 patients in the Control Group and 19 patients in the Delayed Group. Demographics were similar between the groups except for a higher percentage of patients with diabetes, renal failure and history of cancer in Delayed Group (all p  < 0.05). Operative time was longer for Delayed loop ileostomy closure ( p  < 0.05). Patients in the Delayed Group demonstrated a higher hospital readmission rate within 30 days ( p  < 0.05). Both groups had similar return of bowel function on post-operative day 2, similar length of stay, and similar rates of postoperative ileus (p = NS). Delayed loop ileostomy closure more than 12 months after creation does not delay return of bowel function but may lead to higher hospital readmission rates within 30 days.

Abstract Reliable estimates of the impacts of climate change on crop production are critical for assessing the sustainability of food systems. Global, regional, and site-specific crop simulation studies have been conducted for nearly four decades, representing valuable sources of information for climate change impact assessments. However, the wealth of data produced by these studies has not been made publicly available. Here, we develop a global dataset by consolidating previously published meta-analyses and data collected through a new literature search covering recent crop simulations. The new global dataset builds on 8703 simulations from 202 studies published between 1984 and 2020. It contains projected yields of four major crops (maize, rice, soybean, and wheat) in 91 countries under major emission scenarios for the 21st century, with and without adaptation measures, along with geographical coordinates, current temperature and precipitation levels, projected temperature and precipitation changes. This dataset provides a solid basis for a quantitative assessment of the impacts of climate change on crop production and will facilitate the rapidly developing data-driven machine learning applications.

Abstract Disclosure: S.K. Majumdar: None. M. Shapiro: None. L. Bernacet: None. R. Macleod: None. J. Farrell: None. R. Xicola: None. A 25 y.o. woman with a history of Roux en Y gastric bypass (RYGB) presented with recurrent postprandial hypoglycemia beginning about six months after surgery. She became pregnant 17 months after surgery and due to uncontrolled hypoglycemia and malnutrition a gastric tube was placed into her bypassed stomach for continuous tube feeding which reduced hypoglycemic episodes. Hospitalization at 8 weeks gestation did not reveal fasting hypoglycemia, but postprandial episodes were documented by home continuous glucose monitoring. PMH: Obesity, Asthma, PCOS, IBS, and a retinal epithelial pigment abnormality. Family history: Diabetes in her mother. Medications: acarbose, vitamins and famotidine. Exam at 20 weeks gestation: BP 129/79, Pulse 76, Wt 68.9 kg, BMI 26.06 kg/m². Well appearing with unremarkable findings. Prior hospital data: Capillary glucose 85 mg/dL, insulin 21pM (15.6-149.4 pM), C-peptide 596 pM (364-1457 pM), and proinsulin 82.8 pM (< 18.8 pM), with normal renal and liver function. Tube feeding was discontinued after delivery of a healthy girl so provocative testing could be done. Methods: Two supervised meal tests, one home capillary glucose test. Test 1: Sausage and eggs via oral route and test 2: ensure clear (74 gm carbohydrate, 16 gm protein, no fat) via gastric tube into her bypassed stomach. Test 3 was capillary glucose only using ensure by oral route. Result times are T0 = baseline, and Tmin after meal completion. Reference fasting values shown. Results: Test 1(sausage and eggs): T0, T30, T60, T90; Glucose (mg/dL) 80, 173, 71, 58; Insulin (18 - 75 pM) 10.2, 399.6, 57.6, 11.4; C-peptide (364-1457 pM) 433.3, 4500, 2267, 1100, and proinsulin (< 18.8 pM) 73, T30 missing, 462, 170. Test 2 (ensure clear): T0, T30, T60; Glucose 100, 125, 122; Insulin 31, 202, 242; C-peptide 833, 3067, 3300, and proinsulin 150, 872, 812, no hypoglycemia occurred over 4 hours. Test 3 (ensure clear): Glucose 84, 197, 74, 49, 78. Fasting insulin to proinsulin ratios (Tests 1,2): 0.14 and 0.21 (normal ≥ 20). Imaging: CT abdomen, MRI pancreas, Endoscopic ultrasound, and Dotatate PET scan were unrevealing. Hypoglycemia occurred with intake through the bypass route, not gastric route, and was dissociated from proinsulin. RYGB was reversed and genetic testing was done revealing a heterozygous variant in the insulin gene: INS:NM_000207:exon2:c.G164A:p.R55H (hg19: 11:2182038). This variant results in an Arginine to Histidine substitution adjacent to a trypsin cleavage site of proinsulin. Conclusion: We report a case of gastric bypass associated hypoglycemia where initial concerns included a proinsulin secreting tumor, yet meal testing dissociated hypoglycemia from proinsulin values, leading us to pursue bypass reversal and find a rare variant in the INS gene associated with hyperproinsulinemia likely due to impaired proinsulin cleavage. Presentation: Sunday, July 13, 2025

Europe has a long tradition of exploiting marine fishes and is promoting marine economic activity through its Blue Growth strategy. This increase in anthropogenic pressure, along with climate change, threatens the biodiversity of fishes and food security. Here, we examine the conservation status of 1,020 species of European marine fishes and identify factors that contribute to their extinction risk. Large fish species (greater than 1.5 m total length) are most at risk; half of these are threatened with extinction, predominantly sharks, rays and sturgeons. This analysis was based on the latest International Union for Conservation of Nature (IUCN) European regional Red List of marine fishes, which was coherent with assessments of the status of fish stocks carried out independently by fisheries management agencies: no species classified by IUCN as threatened were considered sustainable by these agencies. A remarkable geographic divergence in stock status was also evident: in northern Europe, most stocks were not overfished, whereas in the Mediterranean Sea, almost all stocks were overfished. As Europe proceeds with its sustainable Blue Growth agenda, two main issues stand out as needing priority actions in relation to its marine fishes: the conservation of marine fish megafauna and the sustainability of Mediterranean fish stocks. Assessing the conservation status of 1,020 European marine fishes reveals half of large (>1.5 m) fishes are threatened with extinction and stock status diverges geographically: almost all Mediterranean stock is overfished, most northern European stock is not.

Abstract Reliable estimates of the impacts of climate change on crop production are critical for assessing the sustainability of food systems. Global, regional, and site-specific crop simulation studies have been conducted for nearly four decades, representing valuable sources of information for climate change impact assessments. However, the wealth of data produced by these studies has not been made publicly available. Here, we develop a global dataset by consolidating previously published meta-analyses and data collected through a new literature search covering recent crop simulations. The new global dataset builds on 8703 simulations from 202 studies published between 1984 and 2020. It contains projected yields of four major crops (maize, rice, soybean, and wheat) in 91 countries under major emission scenarios for the 21st century, with and without adaptation measures, along with geographical coordinates, current temperature and precipitation levels, projected temperature and precipitation changes. This dataset provides a solid basis for a quantitative assessment of the impacts of climate change on crop production and will facilitate the rapidly developing data-driven machine learning applications.