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"Ford, Kevin R."
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High knee abduction moments are common risk factors for patellofemoral pain (PFP) and anterior cruciate ligament (ACL) injury in girls: Is PFP itself a predictor for subsequent ACL injury?
by
Myer, Gregory D
,
Micheli, Lyle J
,
Di Stasi, Stephanie L
in
Adolescent
,
Anterior Cruciate Ligament Injuries
,
Athletes
2015
Background Identifying risk factors for knee pain and anterior cruciate ligament (ACL) injury can be an important step in the injury prevention cycle. Objective We evaluated two unique prospective cohorts with similar populations and methodologies to compare the incidence rates and risk factors associated with patellofemoral pain (PFP) and ACL injury. Methods The ‘PFP cohort’ consisted of 240 middle and high school female athletes. They were evaluated by a physician and underwent anthropometric assessment, strength testing and three-dimensional landing biomechanical analyses prior to their basketball season. 145 of these athletes met inclusion for surveillance of incident (new) PFP by certified athletic trainers during their competitive season. The ‘ACL cohort’ included 205 high school female volleyball, soccer and basketball athletes who underwent the same anthropometric, strength and biomechanical assessment prior to their competitive season and were subsequently followed up for incidence of ACL injury. A one-way analysis of variance was used to evaluate potential group (incident PFP vs ACL injured) differences in anthropometrics, strength and landing biomechanics. Knee abduction moment (KAM) cut-scores that provided the maximal sensitivity and specificity for prediction of PFP or ACL injury risk were also compared between the cohorts. Results KAM during landing above 15.4 Nm was associated with a 6.8% risk to develop PFP compared to a 2.9% risk if below the PFP risk threshold in our sample. Likewise, a KAM above 25.3 Nm was associated with a 6.8% risk for subsequent ACL injury compared to a 0.4% risk if below the established ACL risk threshold. The ACL-injured athletes initiated landing with a greater knee abduction angle and a reduced hamstrings-to-quadriceps strength ratio relative to the incident PFP group. Also, when comparing across cohorts, the athletes who suffered ACL injury also had lower hamstring/quadriceps ratio than the players in the PFP sample (p<0.05). Conclusions In adolescent girls aged 13.3 years, >15 Nm of knee abduction load during landing is associated with greater likelihood of developing PFP. Also, in girls aged 16.1 years who land with >25 Nm of knee abduction load during landing are at increased risk for both PFP and ACL injury.
Journal Article
Knee abduction moment is predicted by lower gluteus medius force and larger vertical and lateral ground reaction forces during drop vertical jump in female athletes
by
Ueno, Ryo
,
Ishida, Tomoya
,
Hewett, Timothy E.
in
Anterior cruciate ligament
,
Anterior Cruciate Ligament Injuries - etiology
,
Athletes
2020
Prospective knee abduction moments measured during the drop vertical jump task identify those at increased risk for anterior cruciate ligament injury. The purpose of this study was to determine which muscle forces and frontal plane biomechanical features contribute to large knee abduction moments. Thirteen young female athletes performed three drop vertical jump trials. Subject-specific musculoskeletal models and electromyography-informed simulations were developed to calculate the frontal plane biomechanics and lower limb muscle forces. The relationships between knee abduction moment and frontal plane biomechanics were examined. Knee abduction moment was positively correlated to vertical (R = 0.522, P < 0.001) and lateral ground reaction forces (R = 0.395, P = 0.016), hip adduction angle (R = 0.358, P < 0.023) and lateral pelvic tilt (R = 0.311, P = 0.061). A multiple regression showed that knee abduction moment was predicted by reduced gluteus medius force and increased vertical and lateral ground reaction forces (P < 0.001, R2 = 0.640). Hip adduction is indicative of lateral pelvic shift during landing. The coupled hip adduction and lateral pelvic tilt were associated to the increased vertical and lateral ground reaction forces, propagating into higher knee abduction moments. These biomechanical features are associated with ACL injury and may be limited in a landing with increased activation of the gluteus medius. Targeted neuromuscular training to control the frontal pelvic and hip motion may help to avoid injurious ground reaction forces and consequent knee abduction moment and ACL injury risk.
Journal Article
Analysis of area level and unit level models for small area estimation in forest inventories assisted with LiDAR auxiliary information
by
Mauro, Francisco
,
Monleon, Vicente J.
,
Temesgen, Hailemariam
in
Analysis
,
Biology and Life Sciences
,
Coniferous forests
2017
Forest inventories require estimates and measures of uncertainty for subpopulations such as management units. These units often times hold a small sample size, so they should be regarded as small areas. When auxiliary information is available, different small area estimation methods have been proposed to obtain reliable estimates for small areas. Unit level empirical best linear unbiased predictors (EBLUP) based on plot or grid unit level models have been studied more thoroughly than area level EBLUPs, where the modelling occurs at the management unit scale. Area level EBLUPs do not require a precise plot positioning and allow the use of variable radius plots, thus reducing fieldwork costs. However, their performance has not been examined thoroughly. We compared unit level and area level EBLUPs, using LiDAR auxiliary information collected for inventorying 98,104 ha coastal coniferous forest. Unit level models were consistently more accurate than area level EBLUPs, and area level EBLUPs were consistently more accurate than field estimates except for large management units that held a large sample. For stand density, volume, basal area, quadratic mean diameter, mean height and Lorey's height, root mean squared errors (rmses) of estimates obtained using area level EBLUPs were, on average, 1.43, 2.83, 2.09, 1.40, 1.32 and 1.64 times larger than those based on unit level estimates, respectively. Similarly, direct field estimates had rmses that were, on average, 1.37, 1.45, 1.17, 1.17, 1.26, and 1.38 times larger than rmses of area level EBLUPs. Therefore, area level models can lead to substantial gains in accuracy compared to direct estimates, and unit level models lead to very important gains in accuracy compared to area level models, potentially justifying the additional costs of obtaining accurate field plot coordinates.
Journal Article
Effects of maturation on knee biomechanics during cutting and landing in young female soccer players
2020
Young female soccer players are at high risk of anterior cruciate ligament injury due to the fast-paced nature of the sport and surplus of unplanned movements during play. Neuromuscular training programs that aim to reduce this injury by targeting the associated biomechanical movements are a potential solution. While previous studies have examined the lack of dynamic knee control during landing, there are few that outline the role that maturation can play during unanticipated cutting. Therefore, the purpose of this study was to determine if young female soccer players across multiple phases of maturation exhibited the before seen differences in knee control during a drop landing as well as an unanticipated cutting task. 139 female soccer players volunteered to participate in this study and were classified in three maturational groups based on percent adult stature: prepubertal (PRE), pubertal (PUB), and post-pubertal (POST). Each group performed a drop vertical jump (DVJ) and an unanticipated cutting task (CUT). Standard 3D motion capture techniques were used to determine peak knee flexion/abduction angles and moments during each task. Within tasks, POST exhibited significantly greater peak abduction angles and moments compared to PUB/PRE. While each maturational group exhibited greater peak knee abduction angles during the DVJ compared to the CUT, peak knee abduction moments during the CUT were greater compared to the DVJ. Participants within each maturational group exhibited greater knee flexion during the DVJ compared to the CUT, however there were no differences identified between groups. During both tasks, POST/PUB exhibited greater peak knee flexion moments compared to PRE, as well as POST compared to PUB. Overall, each group exhibited significantly greater peak knee flexion moments during the CUT compared to the DVJ. These observed differences indicate the need for neuromuscular training programs that target both jumping and cutting techniques to reduce ACL injuries.
Journal Article
Outcomes of a randomized controlled trial of neuromuscular training with real-time biofeedback in young female athletes
by
Huang, Bin
,
Taylor, Jeffrey B.
,
Ford, Kevin R.
in
Adolescent
,
Anterior cruciate ligament
,
Anterior Cruciate Ligament Injuries - physiopathology
2025
Background
A large body of scientific work has been focused on reducing the high incidence rate of anterior cruciate ligament (ACL) injuries in young female compared to male soccer players. The purpose of this study was to determine the effects of a randomized clinical trial to reduce a risk factor of ACL injuries, knee abduction moment (KAM), with neuromuscular training and biomechanical biofeedback in adolescent female athletes.
Methods
A prospective, randomized, active comparator, open blinded, end-point trial was conducted with 150 (age: 13.3 ± 2.2 yrs, height: 156.1 ± 1 0.6 cm, mass: 50.2 ± 11.3 kg) female soccer players. Each participant received neuromuscular training and randomized into one of three arms: 1) an active control, considered sham biofeedback (NMT), 2) a knee-focused biofeedback group (NMT + K), and 3) a hip-focused biofeedback group (NMT + H). The participants completed two assessments: a baseline session prior to the intervention and a post-intervention session. The primary outcome measure was change knee abduction moment during a double leg drop vertical jump (DVJ). Additionally, an unplanned single leg cutting task was also recorded. As an exploratory outcome measure, athletic exposures and ACL injuries were recorded weekly for six months following the post-test session.
Results
A statistically significant reduction in KAM, during the DVJ, was found in all three intervention groups from baseline to the post-test (
p
< 0.05). However, statistically significant improvements in KAM during cutting was only observed in the NMT + H intervention group (
p
< 0.05). ACL injuries were not reported in any intervention group during the six months of follow up.
Conclusions
While female soccer players involved in neuromuscular training programs regardless of intervention group exhibit significant improvements in KAM during a double leg landing, those that engage in hip-focused biofeedback compared to knee-focused or sham biofeedback exhibit decreased KAM during an unanticipated cutting maneuver.
Trial registration
The Institutional Review Board at High Point University approved the study protocol. The clinical trial was registered at Clinicaltrials.gov (Identifier: NCT02754700) on 28/04/2016..
Journal Article
Feedback Techniques to Target Functional Deficits Following Anterior Cruciate Ligament Reconstruction: Implications for Motor Control and Reduction of Second Injury Risk
by
Otten, Egbert
,
Gokeler, Alli
,
Hewett, Timothy E.
in
Anterior Cruciate Ligament Injuries
,
Anterior Cruciate Ligament Reconstruction - rehabilitation
,
Arthritis
2013
Primary anterior cruciate ligament (ACL) injury prevention training has been shown to reduce the risk of injury. Less is known about the effect of prevention on second injury after ACL reconstruction (ACLR). Given recent findings that second injury rates exceed 20 % in only the first year following the return to sport, it is imperative that rehabilitation after ACLR is scrutinized so that second injury preventative strategies can be optimized. A potential limitation of current rehabilitative processes following ACLR could be a deficiency in the transition from conscious awareness achieved during rehabilitation sessions to unexpected and automatic movements required for athletic activities on the field. Learning strategies with an internally directed focus have traditionally been utilized but may be less suitable for acquisition of control of complex motor skills required for sport reintegration. Conversely, an externally focused rehabilitation strategy may enhance skill acquisition more efficiently and increase the potential to transfer to competitive sport. This article presents new insights gained from the motor learning domain that may improve neuromuscular training programmes via increased retention from improved techniques and may ultimately reduce the incidence of second ACL injuries.
Journal Article
Spatial Heterogeneity in Ecologically Important Climate Variables at Coarse and Fine Scales in a High-Snow Mountain Landscape
by
Lundquist, Jessica D.
,
Raleigh, Mark S.
,
Hille Ris Lambers, Janneke
in
Analysis
,
Biology
,
Canopies
2013
Climate plays an important role in determining the geographic ranges of species. With rapid climate change expected in the coming decades, ecologists have predicted that species ranges will shift large distances in elevation and latitude. However, most range shift assessments are based on coarse-scale climate models that ignore fine-scale heterogeneity and could fail to capture important range shift dynamics. Moreover, if climate varies dramatically over short distances, some populations of certain species may only need to migrate tens of meters between microhabitats to track their climate as opposed to hundreds of meters upward or hundreds of kilometers poleward. To address these issues, we measured climate variables that are likely important determinants of plant species distributions and abundances (snow disappearance date and soil temperature) at coarse and fine scales at Mount Rainier National Park in Washington State, USA. Coarse-scale differences across the landscape such as large changes in elevation had expected effects on climatic variables, with later snow disappearance dates and lower temperatures at higher elevations. However, locations separated by small distances (∼20 m), but differing by vegetation structure or topographic position, often experienced differences in snow disappearance date and soil temperature as great as locations separated by large distances (>1 km). Tree canopy gaps and topographic depressions experienced later snow disappearance dates than corresponding locations under intact canopy and on ridges. Additionally, locations under vegetation and on topographic ridges experienced lower maximum and higher minimum soil temperatures. The large differences in climate we observed over small distances will likely lead to complex range shift dynamics and could buffer species from the negative effects of climate change.
Journal Article
New method to identify athletes at high risk of ACL injury using clinic-based measurements and freeware computer analysis
by
Myer, Gregory D
,
Hewett, Timothy E
,
Ford, Kevin R
in
Algorithms
,
Anterior Cruciate Ligament Injuries
,
Athletes
2011
Background High knee abduction moment (KAM) landing mechanics, measured in the biomechanics laboratory, can successfully identify female athletes at increased risk for anterior cruciate ligament (ACL) injury. Methods The authors validated a simpler, clinic-based ACL injury prediction algorithm to identify female athletes with high KAM measures. The validated ACL injury prediction algorithm employs the clinically obtainable measures of knee valgus motion, knee flexion range of motion, body mass, tibia length and quadriceps-to-hamstrings ratio. It predicts high KAMs in female athletes with high sensitivity (77%) and specificity (71%). Conclusion This report outlines the techniques for this ACL injury prediction algorithm using clinic-based measurements and computer analyses that require only freely available public domain software.
Journal Article
Sex Differences in Proximal Control of the Knee Joint
by
Alentorn-Geli, Eduard
,
Hewett, Timothy E.
,
Quatman, Carmen E.
in
Abdomen - anatomy & histology
,
Abdomen - physiology
,
Anterior cruciate ligament
2011
Following the onset of maturation, female athletes have a significantly higher risk for anterior cruciate ligament (ACL) injury compared with male athletes. While multiple sex differences in lower-extremity neuromuscular control and biomechanics have been identified as potential risk factors for ACL injury in females, the majority of these studies have focused specifically on the knee joint. However, increasing evidence in the literature indicates that lumbo-pelvic (core) control may have a large effect on knee-joint control and injury risk. This review examines the published evidence on the contributions of the trunk and hip to knee-joint control. Specifically, the sex differences in potential proximal controllers of the knee as risk factors for ACL injury are identified and discussed. Sex differences in trunk and hip biomechanics have been identified in all planes of motion (sagittal, coronal and transverse). Essentially, female athletes show greater lateral trunk displacement, altered trunk and hip flexion angles, greater ranges of trunk motion, and increased hip adduction and internal rotation during sport manoeuvres, compared with their male counterparts. These differences may increase the risk of ACL injury among female athletes. Prevention programmes targeted towards trunk and hip neuromuscular control may decrease the risk for ACL injuries.
Journal Article
Footwear-Induced Differences in Biomechanics and Perceived Comfort During Unanticipated Side-Step Cutting: An Exploratory Study in Female Football Players
2026
Cleated footwear in football increasingly incorporates sex-specific design features intended to address a clear gap in anthropometric and biomechanical differences in female athletes. However, experimental evidence evaluating how these designs may influence lower-extremity biomechanics during sport tasks in female athletes remains limited. The purpose of this exploratory pilot study was to examine the effects of sex-specific footwear on lower-extremity biomechanics, plantar pressure distribution, and perceived comfort in female football players during unanticipated side-step cutting. The study used a controlled laboratory-based repeated measures design. Twenty female football players performed unanticipated side-step cutting tasks in two randomized footwear conditions: a standard commercially available control cleat (CT) and a female-specific prototype cleat (PT). Ankle and knee biomechanics, in-shoe pressure distribution, and subjective comfort ratings were assessed. Compared with the CT, the PT cleat had reduced peak ankle inversion angle, inversion angular velocity, and inversion moment, indicating altered ankle biomechanics during cutting. No differences were observed in knee abduction between footwear conditions. However, participants subjectively rated greater comfort in CT compared to PT. Peak pressure was higher in the midfoot and central forefoot in the PT footwear compared to the CT. Given the pilot nature of the study, with multiple footwear alterations, the findings should be interpreted as hypothesis-generating and used to inform future targeted investigations.
Journal Article