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"Francis, Daniel"
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Where mountains meet the sea : an illustrated history of the District of North Vancouver
\"Where Mountains Meet the Sea commemorates the 125th anniversary of the District of North Vancouver's incorporation as a municipality. Combining hundreds of illustrations with the personal accounts of residents and a lively text, the book presents the story of North Vancouver in all its colour and complexity. Instead of a conventional chronological narrative, Where Mountains Meet the Sea divides the story of North Vancouver's development into three major parts: 1) the origins of the community, its First Nations residents and the development of its waterfront; 2) the political and cultural evolution of the community; and 3) the development of the mountain resorts and the creation of the many parks which characterize the North Shore. From the District's auspicious beginnings with the sawmill at Moodyville dominating the industry of Burrard Inlet, through the postwar population boom that saw the municipality evolve from a suburb of Vancouver into a bustling community in its own right, to the District's rich legacy of outdoor recreation, the text, residents' anecdotes and photographs create a vivid portrait of the development of a thriving community. Each section of the book is richly illustrated in full colour with biographies, eyewitness memories, artifacts from the collection of the North Vancouver Museum and Archives, historic photographs, maps and charts.\"-- Provided by publisher.
Book
MONOPOLIZING BY CONDITIONING
Across the economy, monopolists of all kinds are engaged in “conditional dealing.” This is the practice of unilaterally offering benefits and penalties, or bribes and threats, to induce trading partners to refrain from competing against the monopolist or from dealing with its rivals. Pharma giants offer discounts conditioned on “loyalty,” agricultural monopolists impose “exit penalties” for switching to rivals, and social networks offer interoperability for apps only so long as they don’t compete.
Economic scholarship shows that conditional dealing can inflict serious harms, but the law has not caught up. In particular, harmful conditioning goes undeterred because it falls into the gaps between the categories of our fragmented monopolization law. Courts have repeatedly tried to squeeze conditioning into ill-fitting categories, rejected claims on the basis of economically irrelevant criteria, and sometimes thrown up their hands altogether. The result: shambolic doctrine, tolerance of harmful behavior, and the collapse of enforcement efforts.
Conditional dealing should be recognized as a new category of monopolizing conduct. To that end, this Article provides a new analytical framework: a definition of conditioning, as well as standards for gauging its exclusionary impact, contribution to power, and procompetitive justifications. It explains why a host of criteria often applied by courts—from price-cost and “coercion” tests to quantitative foreclosure screens—should be jettisoned. And it sketches two further ideas with broader implications for antitrust: a framework of “quick look monopolization” for nakedly harmful conditioning and a reinterpretation of the “attempted monopoly maintenance” offense to tackle knowing misconduct in complex markets.
Journal Article
روبنسون كروزو
قصة كتبها دانيال ديفو، نشرت للمرة الأولى سنة 1719. تعد أحيانا الرواية الأولى في الإنجليزية. هذه الرواية هي سيرة ذاتية تخيلية وهي تحكى عن شاب انعزل في جزيرة ما، وحيدا لمدة طويلة دون أن يقابل أحد من البشر، ثم بعد عدة سنوات يقابل أحد المتوحشين وعلمه بعض ما وصل اليه الإنسان المتحضر من تقدم فكري وجعله خادمه. وفي نهاية القصة عاد روبنسون كروزو ومعه خادمه إلى أوروبا حيث العالم المتحضر. وهذه القصة تعني إلى الكثيرين حلم الانعزال عن هذا العالم الظالم والحياة في ظل الطبيعة الرحيمة بالنسبة لهذا العالم كما تظهر مدى التحضر الذي توصلت له الأمم الأوربية. هذه التقنية تعرف باسم الوثيقة الخاطئة، وهي تعطي شكلا واقعيا للقصة.
BOOK
Proposed methodology for site-specific soil moisture obtainment utilizing coarse satellite-based data
Soil moisture is an important prognostic variable within a soil and climate system. Soil moisture is often used in the analysis of soil and crop health, determining the probability of natural hazard occurrence, and of the overall climatology. However, obtaining soil moisture measurements that are comprehensive with respect to a study area is often a tedious and costly endeavor. Globally available satellite-based soil moisture retrievals yield a unique solution to this problem. Although globally available, these estimates are typically at too coarse a resolution for use in site-specific analyses. For this reason, this study presents a comparative analysis upon the efficacy of methods used to remotely obtain site-specific moisture estimates from these satellite-based moisture data sets. In the geoscience and remote-sensing communities, downscaling or assimilation methods are traditionally used to obtain desired site-specific moisture estimates. This study investigated Random Forest and Soil Evaporative Efficiency (SEE) downscaling methods as well as an Ensemble Kalman Filter (EnKF)-based assimilation method to obtain site-specific moisture data. This study also proposes a less intensive approach which was observed to effectively yield site-specific soil moisture estimates from satellite-based moisture datasets. The proposed approach developed a multivariate regression analysis which characterized relationships between site-specific soil texture data and SMAP L4_SM root zone soil moisture correction factors. This approach was conducted over various in-situ sites across the Commonwealth of Kentucky to yield site-specific L4_SM soil moisture estimates. These sites served as control sites, whereas the developed regression approach was able to be validated. Through qualitative and quantitative analyses, it was found that the EnKF and proposed multivariate regression approaches performed strongly when compared to site-specific in-situ measurements. These analyses accounted for both the accuracy of the site-specific products as compared to in-situ data and the efforts required to complete the approach. The study presented herein shows that the proposed multivariate regression approach is far less intensive, yet still yields site-specific moisture estimates comparable to that of downscaling or assimilated approaches.
Journal Article
I'd die for you : and other lost stories
\"Known not only for his brilliant novels but also for short stories chronicling the Jazz Age, such as 'Bernice bobs her hair' and 'The diamond as big as the Ritz,' F. Scott Fitzgerald continued to write stories his entire life, some of which were never published--until now. Many of the stories in I'd die for you were submitted to major magazines and accepted for publication during Fitzgerald's lifetime but were never printed. A few were written as movie scenarios and sent to studios or producers, but not filmed. Others are stories that could not be sold because their subject matter or style departed from what editors expected of Fitzgerald in the 1930s. They come from various sources, from library archive to private collections, including those of Fitzgerald's family\"--Jacket flap.
Book
Discovery, characterization and engineering of ligases for amide synthesis
Coronatine and related bacterial phytotoxins are mimics of the hormone jasmonyl-
l
-isoleucine (JA-Ile), which mediates physiologically important plant signalling pathways
1
,
2
,
3
–
4
. Coronatine-like phytotoxins disrupt these essential pathways and have potential in the development of safer, more selective herbicides. Although the biosynthesis of coronatine has been investigated previously, the nature of the enzyme that catalyses the crucial coupling of coronafacic acid to amino acids remains unknown
1
,
2
. Here we characterize a family of enzymes, coronafacic acid ligases (CfaLs), and resolve their structures. We found that CfaL can also produce JA-Ile, despite low similarity with the Jar1 enzyme that is responsible for ligation of JA and
l
-Ile in plants
5
. This suggests that Jar1 and CfaL evolved independently to catalyse similar reactions—Jar1 producing a compound essential for plant development
4
,
5
, and the bacterial ligases producing analogues toxic to plants. We further demonstrate how CfaL enzymes can be used to synthesize a diverse array of amides, obviating the need for protecting groups. Highly selective kinetic resolutions of racemic donor or acceptor substrates were achieved, affording homochiral products. We also used structure-guided mutagenesis to engineer improved CfaL variants. Together, these results show that CfaLs can deliver a wide range of amides for agrochemical, pharmaceutical and other applications.
A family of enzymes—coronafacic acid ligases, involved in the synthesis of bacterial phytotoxins—are found to catalyse amide bond formation with a wide range of substrates.
Journal Article
Secret empire
After a cosmic cube rewrites Captain America's history, he becomes the ultimate sleeper agent and is poised to embrace his destiny as Hydra's supreme leader. As his plans unfold, will there be anyone left to stand against him?
Book
Predictive score for cervicofacial cellulitis severity: development and validation of a multidisciplinary tool in Sub-Saharan Africa
Background
Cervicofacial cellulitis represents serious infectious emergencies with high morbidity and mortality in resource-limited settings. This study aimed to develop and validate a predictive score for cervicofacial cellulitis severity specifically adapted to the African context.
Methods
A retrospective observational study was conducted on 127 patients hospitalized for cervicofacial cellulitis between January 2020 and December 2023 in Yaoundé Central Hospital, Cameroon. Multivariate logistic regression identified independent predictive factors of severe complications, defined as respiratory distress requiring mechanical ventilation, septic shock, mediastinitis, or in-hospital death. A point-based scoring system was developed and internally validated using bootstrap methodology.
Results
Mean age was 42.3 ± 16.8 years with male predominance (54.3%). Five independent predictive factors emerged: age over 55 years (OR = 2.4), dyspnea (OR = 6.8), trismus (OR = 3.2), white blood cell count over 12,000/mm³ (OR = 2.8), and cervical extension (OR = 4.1). The predictive score demonstrated excellent discriminative capacity with area under the ROC curve of 0.89 (95% CI: 0.83–0.95), sensitivity 88.9%, and specificity 82.6%. Three-tier risk stratification identified low-risk patients (2.3% severe complications), moderate-risk patients (28.6% severe complications), and high-risk patients (71.4% severe complications). Overall mortality was 7.9%.
Conclusions
This validated predictive score enables systematic risk stratification using readily available clinical and laboratory parameters in resource-limited settings. The tool demonstrates superior performance compared to clinical judgment alone and facilitates evidence-based resource allocation. External validation across diverse African populations is warranted before widespread implementation.
Journal Article
X-Men : the age of Apocalypse. Vol. 2. Reign
The world groans under the Darwinian conqueror Apocalypse's rule. Under his thumb, America has become a dark and dangerous dystopia where mutants rule, humankind suffers, and survival of the fittest is all! But in the shadows, the freedom fighters known as the X-Men - following a tenuously thin thread of hope - continue their dangerous and multi-pronged plan to restore the true Marvel Universe.
BOOK
The 2023 Merger Guidelines and the Arc of Antitrust History
In 2023, the federal antitrust agencies rewrote the nation's flagship merger policy document, as part of a broader “Neo-Brandeisian” effort to bring about a deep reform of the antitrust system. The result—the 2023 Merger Guidelines—has been highly controversial: celebrated by some as a revolutionary advance, and criticized by others as a step back toward a benighted past. This article evaluates the 2023 guidance against the arc of antitrust's modern history. It argues that the new guidance breaks a long trend of migration from structure toward welfare as the primary orientation of merger enforcement, but that it does so cautiously, by achieving a fraught ambiguity between welfarist and nonwelfarist policies. In inviting both revolutionary and evolutionary readings, the agencies have sacrificed clarity and discouraged beneficial deals, but they have also deferred—at least for now—a sharp conflict between those who would preserve antitrust's governing paradigm and those who would remake it.
Journal Article