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63 result(s) for "Frezza, Fabrizio"
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Cancer Diagnosis Using Deep Learning: A Bibliographic Review
In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann’s machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements.
Efficient Integration of Ultra-low Power Techniques and Energy Harvesting in Self-Sufficient Devices: A Comprehensive Overview of Current Progress and Future Directions
Compact, energy-efficient, and autonomous wireless sensor nodes offer incredible versatility for various applications across different environments. Although these devices transmit and receive real-time data, efficient energy storage (ES) is crucial for their operation, especially in remote or hard-to-reach locations. Rechargeable batteries are commonly used, although they often have limited storage capacity. To address this, ultra-low-power design techniques (ULPDT) can be implemented to reduce energy consumption and prolong battery life. The Energy Harvesting Technique (EHT) enables perpetual operation in an eco-friendly manner, but may not fully replace batteries due to its intermittent nature and limited power generation. To ensure uninterrupted power supply, devices such as ES and power management unit (PMU) are needed. This review focuses on the importance of minimizing power consumption and maximizing energy efficiency to improve the autonomy and longevity of these sensor nodes. It examines current advancements, challenges, and future direction in ULPDT, ES, PMU, wireless communication protocols, and EHT to develop and implement robust and eco-friendly technology solutions for practical and long-lasting use in real-world scenarios.
Deep Learning Hybrid Techniques for Brain Tumor Segmentation
Medical images play an important role in medical diagnosis and treatment. Oncologists analyze images to determine the different characteristics of deadly diseases, plan the therapy, and observe the evolution of the disease. The objective of this paper is to propose a method for the detection of brain tumors. Brain tumors are identified from Magnetic Resonance (MR) images by performing suitable segmentation procedures. The latest technical literature concerning radiographic images of the brain shows that deep learning methods can be implemented to extract specific features of brain tumors, aiding clinical diagnosis. For this reason, most data scientists and AI researchers work on Machine Learning methods for designing automatic screening procedures. Indeed, an automated method would result in quicker segmentation findings, providing a robust output with respect to possible differences in data sources, mostly due to different procedures in data recording and storing, resulting in a more consistent identification of brain tumors. To improve the performance of the segmentation procedure, new architectures are proposed and tested in this paper. We propose deep neural networks for the detection of brain tumors, trained on the MRI scans of patients’ brains. The proposed architectures are based on convolutional neural networks and inception modules for brain tumor segmentation. A comparison of these proposed architectures with the baseline reference ones shows very interesting results. MI-Unet showed a performance increase in comparison to baseline Unet architecture by 7.5% in dice score, 23.91% insensitivity, and 7.09% in specificity. Depth-wise separable MI-Unet showed a performance increase by 10.83% in dice score, 2.97% in sensitivity, and 12.72% in specificity as compared to the baseline Unet architecture. Hybrid Unet architecture achieved performance improvement of 9.71% in dice score, 3.56% in sensitivity, and 12.6% in specificity. Whereas the depth-wise separable hybrid Unet architecture outperformed the baseline architecture by 15.45% in dice score, 20.56% in sensitivity, and 12.22% in specificity.
Leaky Wave Generation Through a Phased-Patch Array
For this article, we approximated the field of a leaky-wave antenna (LWA) with the field produced by a uniform linear array (ULA). This article aims to provide an initial framework for applications where the generation of an inhomogeneous wave is wished, but, at the same time, a flexibility is required that is difficult to meet with the conventional LWA design. In particular, two different configurations were considered, one with a simple Menzel antenna operating at 12 GHz, and one, relevant for practical applications, with an antenna operating at 2.4 GHz. This study aimed, in both cases, to highlight the distance at which the field produced by the phased array with the chosen sampling method can approximate effectively the one produced by a leaky-wave antenna and to verify whether this could cause issues for the targeted application.
Simple and Cost-Effective Design of a THz-Metamaterial-Based Hybrid Sensor on a Single Substrate
This study presents a cost-effective Hybrid Metamaterial Absorber (HMA) featuring a simple circular-patterned cylindrical design, comprising an indium antimonide (InSb) resonator on a thin copper sheet. Through numerical simulations, we demonstrate that the structure exhibits temperature-tunable properties and refractive index sensitivity. At 300 K (refractive index = 1), a peak absorption of 99.94% is achieved at 1.797 THz. Efficient operation is observed across a 40 K temperature range and a refractive index spectrum of 1.00–1.05, relevant for thermal imaging and spatial bio-sensing. The simulated temperature sensing sensitivity is 13.07 GHz/K, and the refractive index sensitivity is 1146 GHz/RIU. Parametric analyses reveal tunable absorption through adjustments of the InSb resonator design parameters. Owing to its high efficiency and sensitivity demonstrated in simulations, this HMA shows promise for sensing applications in biotechnology, semiconductor fabrication, and energy harvesting.
All-Metal Metamaterial-Based Sensor with Novel Geometry and Enhanced Sensing Capability at Terahertz Frequency
This research proposes an all-metal metamaterial-based absorber with a novel geometry capable of refractive index sensing in the terahertz (THz) range. The structure consists of four concentric diamond-shaped gold resonators on the top of a gold metal plate; the resonators increase in height by 2 µm moving from the outer to the inner resonators, making the design distinctive. This novel configuration has played a very significant role in achieving multiple ultra-narrow resonant absorption peaks that produce very high sensitivity when employed as a refractive index sensor. Numerical simulations demonstrate that it can achieve six significant ultra-narrow absorption peaks within the frequency range of 5 to 8 THz. The sensor has a maximum absorptivity of 99.98% at 6.97 THz. The proposed absorber also produces very high-quality factors at each resonance. The average sensitivity is 7.57/Refractive Index Unit (THz/RIU), which is significantly high when compared to the current state of the art. This high sensitivity is instrumental in detecting smaller traces of samples that have very correlated refractive indices, like several harmful gases. Hence, the proposed metamaterial-based sensor can be used as a potential gas detector at terahertz frequency. Furthermore, the structure proves to be polarization-insensitive and produces a stable absorption response when the angle of incidence is increased up to 60°. At terahertz wavelength, the proposed design can be used for any value of the aforementioned angles, targeting THz spectroscopy-based biomolecular fingerprint detection and energy harvesting applications.
Electromagnetic Techniques Applied to Cultural Heritage Diagnosis: State of the Art and Future Prospective: A Comprehensive Review
When discussing Cultural Heritage (CH), the risk of causing damage is inherently linked to the artifact itself due to several factors: age, perishable materials, manufacturing techniques, and, at times, inadequate preservation conditions or previous interventions. Thorough study and diagnostics are essential before any intervention, whether for preventive, routine maintenance or major restoration. Given the symbolic, socio-cultural, and economic value of CH artifacts, non-invasive (NI), non-destructive (ND), or As Low As Reasonably Achievable (ALARA) approaches—capable of delivering efficient and long-lasting results—are preferred whenever possible. Electromagnetic (EM) techniques are unrivaled in this context. Over the past 20 years, radiography, tomography, fluorescence, spectroscopy, and ionizing radiation have seen increasing and successful applications in CH monitoring and preservation. This has led to the frequent customization of standard instruments to meet specific diagnostic needs. Simultaneously, the integration of terahertz (THz) technology has emerged as a promising advancement, enhancing capabilities in artifact analysis. Furthermore, Artificial Intelligence (AI), particularly its subsets—Machine Learning (ML) and Deep Learning (DL)—is playing an increasingly vital role in data interpretation and in optimizing conservation strategies. This paper provides a comprehensive and practical review of the key achievements in the application of EM techniques to CH over the past two decades. It focuses on identifying established best practices, outlining emerging needs, and highlighting unresolved challenges, offering a forward-looking perspective for the future development and application of these technologies in preserving tangible cultural heritage for generations to come.
A Survey of Electromagnetic Techniques Applied to Cultural Heritage Conservation
Cultural Heritage (CH) represents the identity of populations; it is a heritage not only for the culture that produced it, but also for the entire human civilization. Still, preserving it is not an easy task; several factors hinder its preservation, from time and natural disasters to wars and neglect. Science can play a leading role in preserving CH, and among the different techniques available, Electromagnetic (EM) techniques are particularly suitable for this purpose because of their efficacy, safety for both people and materials, and their applicability to artifacts made from different materials and of complex and irregular shapes. Although usually associated with diagnostic applications, EM techniques also have a crucial role in restoration applications thanks to EM radiation treatments for the recovery and consolidation of materials such as wood, paper, parchment, stone, ceramics, and mummies. The state-of-the-art of radiation technologies shows efficacy for the elimination of pests, mold, fungi and bacteria, and for the consolidation of damaged or weakened artifacts. This paper aims to provide a useful tool for a first yet rigorous understanding of the contribution of EM techniques to CH recovery and lifetime extension, also comparing them with traditional methods and highlighting main issues in their application, such as lack of protocols and distrust, and potential risks in their application.
Machine Learning Approaches for Skin Cancer Classification from Dermoscopic Images: A Systematic Review
Skin cancer (SC) is one of the most prevalent cancers worldwide. Clinical evaluation of skin lesions is necessary to assess the characteristics of the disease; however, it is limited by long timelines and variety in interpretation. As early and accurate diagnosis of SC is crucial to increase patient survival rates, machine-learning (ML) and deep-learning (DL) approaches have been developed to overcome these issues and support dermatologists. We present a systematic literature review of recent research on the use of machine learning to classify skin lesions with the aim of providing a solid starting point for researchers beginning to work in this area. A search was conducted in several electronic databases by applying inclusion/exclusion filters and for this review, only those documents that clearly and completely described the procedures performed and reported the results obtained were selected. Sixty-eight articles were selected, of which the majority use DL approaches, in particular convolutional neural networks (CNN), while a smaller portion rely on ML techniques or hybrid ML/DL approaches for skin cancer detection and classification. Many ML and DL methods show high performance as classifiers of skin lesions. The promising results obtained to date bode well for the not-too-distant inclusion of these techniques in clinical practice.
Verification of the electromagnetic deep-penetration effect in the real world
The deep penetration of electromagnetic waves into lossy media can be obtained by properly generating inhomogeneous waves. In this work, for the very first time, we demonstrate the physical implementation and the practical relevance of this phenomenon. A thorough numerical investigation of the deep-penetration effects has been performed by designing and comparing three distinct practical radiators, emitting either homogeneous or inhomogeneous waves. As concerns the latter kind, a typical Menzel microstrip antenna is first used to radiate improper leaky waves. Then, a completely new approach based on an optimized 3-D horn TEM antenna applied to a lossy prism is described, which may find applications even at optical frequencies. The effectiveness of the proposed radiators is measured using different algorithms to consider distinct aspects of the propagation in lossy media. We finally demonstrate that the deep penetration is possible, by extending the ideal and theoretical evidence to practical relevance, and discuss both achievements and limits obtained through numerical simulations on the designed antennas.