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This paper addresses the controversy between Koeneman & Zeijlstra (K&Z) (2014) and Heycock & Sundquist (2017) concerning the viability of K&Z’s strong version of the Rich Agreement Hypothesis in the light of apparent counterexamples from the diachrony of Danish. It makes the general point that establishing whether or not cases of putative V-to-I movement in subordinate clauses can be reanalyzed as V-to-C, i.e. as embedded Verb Second (EV2), depends on the EV2-type of a language. The empirical discussion concerns appositive relatives and conditional protases, with V-to-C in the former being in principle compatible with ‘narrow’ nEV2 as displayed by Modern Mainland Scandinavian languages, and V-to-C in the latter with Old Norse-style ‘broad’ bEV2. It is concluded that the critical stages of Danish need to be scrutinized more closely before the above dispute can be settled.

Antibiotic‐resistant enterococci represent a significant global health challenge. Unfortunately, most β‐lactam antibiotics are not applicable for enterococcal infections due to intrinsic resistance. To extend their antimicrobial spectrum, polycationic peptides are conjugated to examples from each of the four classes of β‐lactam antibiotics. Remarkably, the β‐lactam–peptide conjugates gained an up to 1000‐fold increase in antimicrobial activity against vancomycin‐susceptible and vancomycin‐resistant enterococci. Even against β‐lactam‐resistant Gram‐negative strains, the conjugates are found to be effective despite their size exceeding the exclusion volume of porins. The extraordinary gain of activity can be explained by an altered mode of killing. Of note, the conjugates showed a concentration‐dependent activity in contrast to the parent β‐lactam antibiotics that exhibited a time‐dependent mode of action. In comparison to the parent β‐lactams, the conjugates showed altered affinities to the penicillin‐binding proteins. Furthermore, it is found that peptide conjugation also resulted in a different elimination route of the compounds when administered to rodents. In mice systemically infected with vancomycin‐resistant enterococci, treatment with a β‐lactam–peptide conjugate reduced bacterial burden in the liver compared to its originator. Therefore, peptide modification of β–lactam antibiotics represents a promising platform strategy to broaden their efficacy spectrum, particularly against enterococci. Novel potent compounds are urgently required for the treatment of antibiotic‐resistant bacteria. Conjugation of polycationic peptides to β‐lactam antibiotics extends their efficacy spectrum against enterococci. The β‐lactam–peptide conjugates show significant differences in mechanism and biodistribution compared to their originators. Due to their high potency, the β‐lactam–peptide conjugates can serve as an alternative treatment option for severe enterococcal infections.

Human language is a phenomenon of immense richness: It provides finely nuanced means of expression that underlie the formation of culture and society; it is subject to subtle, unexpected constraints like syntactic islands and cross-over phenomena; different mutually-unintelligeable individual languages are numerous; and the descriptions of individual languages occupy thousands of pages. Recent work in linguistics, however, has tried to argue that despite all appearances to the contrary, the human biological capacity for language may be reducible to a small inventory of core cognitive competencies. The most radical version of this view has emerged from the Minimalist Program: The claim that language consists of only the ability to generate recursive structures by a computational mechanism. On this view, all other properties of language must result from the interaction at the interfaces of that mechanism and other mental systems not exclusively devoted to language. Since language could then be described as the simplest recursive system satisfying the requirements of the interfaces, one can speak of the Minimalist Equation: Interfaces + Recursion = Language. The question whether all the richness of language can be reduced to that minimalist equation has already inspired several fruitful lines of research that led to important new results. While a full assessment of the minimalist equation will require evidence from many different areas of inquiry, this volume focuses especially on the perspective of syntax and semantics. Within the minimalist architecture, this places our concern with the core computational mechanism and the (LF-)interface where recursive structures are fed to interpretation. Specific questions that the papers address are: What kind of recursive structures can the core generator form? How can we determine what the simplest recursive system is? How can properties of language that used to be ascribed to the recursive generator be reduced to interface properties? What effects do syntactic operations have on semantic interpretation? To what extent do models of semantic interpretation support the LF-interface conditions postulated by minimalist syntax?

Clause Structure and Adjuncts in Austronesian Languages is a collection of papers devoted to the syntactic analysis of modification and extraction strategies in Austronesian languages such as Kavalan, Malagasy, Niuean, Seediq, and Tagalog. Written by some of the leading scholars in the field, it elucidates the categorial and phrase structural status as well as the scopal behavior of sentence-level adverbs, ordering constraints on adjectival modifiers, and the nature of unbounded dependencies in interaction with Philippine-type voice systems. Guglielmo Cinque's universal ordering hypothesis for adverbs and current work on remnant movement serve as theoretical points of reference. More particularly the book contains an analysis of lower VP-adverbs in Kavalan as serial verbs (Chang), a defense of two types of adverbial heads in Seediq (Holmer), an account of possible DP-internal serializations in Niuean in terms of remnant movement (Kahnemuyipour Massam), a plea for relative, scope-based adverb ordering in Tagalog (Kaufman), a clefting approach to unbounded dependencies in Malagasy (Potsdam), a critical assessment of constraints on remnant movement as applied to adverb orderings in Malagasy (Thiersch), and an analysis of the Malagasy voice system on the basis of clitic left-dislocation (Travis). The editors' introduction undertakes a critical survey of the relevant empirical and theoretical background. A substantial part of the empirical facts are presented here for the first time, and the book will inspire additional systematic investigation of the often neglected aspects of modificational strategies in Austronesian languages. The book will be of value to linguists interested in contemporary syntactic analysis and to everyone seeking a deeper understanding of the formal properties of Austronesian.

This paper explores the pros and cons of assimilating Malagasy \"Focusing\" Afo-Constructions (FNCs) to Temporal No-Constructions (TNCs), which arise from the combination of two full-fledged clauses. The particle no functions as a clause-linker introducing an adverbial clause. It is shown that a neo-Davidsonian semantics assimilating FNCs to TNCs can be developed. Among the attractive consequences of this is the possibility of giving pre-no quantifiers a standard (non predicative) semantics. The clause combining approach also squares well with the finding that the \"focusing\" nature of FNCs is less regular than often assumed. In particular, non-backgrounded (non-\" presupposed\") woclauses can be found. Among the drawbacks of a clause combining approach is its apparent inability to properly constrain \"binding\" relations between the two clauses. In particular, locality restrictions typical for movement relations are unpredicted. The paper discusses these features in some detail against the backdrop of rivaling movement and pseudocleft approaches.My hope is that it helps in clarifying their strengths and weaknesses. Also, I show that formal semantics is a useful, hitherto often neglected, tool with some potential of furthering our understanding the nature of Malagasy FNCs.

This squib provides counterexamples to the claim that Icelandic reflexive sig cannot be construed logophorically if immediately contained inside an infinitival clause. Consequences for Eric Reuland's views on the division of labor between grammar and pragmatics are discussed.

This paper describes a construction from (spoken) German that will be called integrated verb second (IV2). This term refers to V2 clauses that look like relative clauses except that they must contain a weak demonstrative in initial position and have to be extraposed. Their syntactic behavior will be accounted for by a paratactic analysis. IV2 can only modify wide scope indefinites inside what looks like the matrix clause. This is captured at the level of DRS construction. Since the matrix clause alone doesn't constitute a complete informational unit, IV2 can be introduced as a condition into the matrix DRS before evaluation. The weak demonstrative of IV2 establishes the relative link by copying a top-level discourse marker. In addition, the assertional nature of IV2 prevents it from modifying definite descriptions. Reference is made to the close relatedness of demonstrative and relative pronouns in Indo-European. Dutch, Swedish, and Zurich German provide the comparative horizon of this study. My answer to the question in the title is negative from the syntactic perspective but positive with reference to interpretation.