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result(s) for
"Gabriel Frederick"
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Ontology-Based Data Pipeline for Semantic Reaction Classification and Research Data Management
by
Borgelt, Hendrik
,
Kockmann, Norbert
,
Kitel, Frederick Gabriel
in
Application programming interface
,
Applications programming
,
Catalysis
2025
Catalysis research is complex and interdisciplinary, involving diverse physical effects and challenging data practices. Research data often captures only selected aspects, such as specific reactants and products, limiting its utility for machine learning and the implementation of FAIR (Findable, Accessible, Interoperable, Reusable) workflows. To improve this, semantic structuring through ontologies is essential. This work extends the established ontologies by refining logical relations and integrating semantic tools such as the Web Ontology Language or the Shape Constraint Language. It incorporates application programming interfaces from chemical databases, such as the Kyoto Encyclopedia of Genes and Genomes and the National Institute of Health’s PubChem database, and builds upon established ontologies. A key innovation lies in automatically decomposing chemical substances through database entries and chemical identifier representations to identify functional groups, enabling more generalized reaction classification. Using new semantic functionality, functional groups are flexibly addressed, improving the classification of reactions such as saponification and ester cleavage with simultaneous oxidation. A graphical interface (GUI) supports user interaction with the knowledge graph, enabling ontological reasoning and querying. This approach demonstrates improved specificity of the newly established ontology over its predecessors and offers a more user-friendly interface for engaging with structured chemical knowledge. Future work will focus on expanding ontology coverage to support a wider range of reactions in catalysis research.
Journal Article
Physician Soldier
Frederick R. Gabriel graduated from medical school in 1940, entered the US Army, and was assigned to the newly-created 39th Station Hospital. His letters from the Pacific theater—especially from Guadalcanal, Angaur, and Saipan—capture the everyday life of a soldier physician. His son, Michael P. Gabriel, a professional historian, has faithfully preserved, edited, and annotated that correspondence to add a new dimension to our understanding of the social history of World War II, which he presents here in Physician Soldier: The South Pacific Letters of Captain Fred Gabriel from the 39th Station Hospital . Like most wartime hospitals, the 39th Station Hospital was positioned in a rear area and saw limited direct action. And like most wartime hospitals, the 39th Station Hospital spent each day confronting the injuries and casualties of frontline combat. Gabriel supervised a ward and oversaw the unit’s laboratory, serving a hospital that provided care to four hundred patients at a time. Gabriel’s letters home capture this experience and more, providing a revealing look into day-to-day life in the Pacific theater. He discusses the training of medical officers and female nurses, recreational activities such as Bob Hope’s USO show, and even his thoughts on the death of FDR, the end of the war in Europe, and ultimately the horrors of the atomic bomb.
Neuro-ophthalmological findings in TAFRO syndrome in a patient from South America, a variant of multicentric Castleman’s disease
2018
BackgroundTo report the neuro-ophthalmological findings in the TAFRO syndrome in a South American patient.MethodsThis is a case report of a patient with TAFRO syndrome.ResultsWe present the case of a 66-year-old woman with TAFRO syndrome and multicentric Castleman disease, who developed ophthalmic manifestations, as a rare complication, including optic disk edema and serous retinal detachment, which improved with conventional therapy.ConclusionsThe optic disk edema could be present as a neuro-ophthalmological finding in TAFRO syndrome. To the best of our knowledge, this is the first report on the ophthalmic manifestations in the TAFRO syndrome.
Journal Article
Massive hyphaema following laser iridotomy in a patient on dual antiplatelet therapy (aspirin plus ticagrelor) : case report and literature review
by
Carreño, Néstor I.
,
Frederick, Gabriel A.
,
Blanco, Nicolas A.
in
Anticoagulants
,
Aspirin
,
Blood platelets
2019
Massive hyphaema presentation after a laser iridotomy is very rare. We report a 63-year-old man with
ischaemic heart disease on dual antiplatelet therapy (aspirin plus ticagrelor) who was diagnosed as a primary angle-closure
suspect and was to undergo a neodymium-doped yttrium aluminium garnet laser iridotomy at Centro Oftalmologico
Virgilio Galvis, Floridablanca, Colombia in 2016. While performing the iridotomy in the left eye, active bleeding occurred
that finally filled approximately 75 % of the anterior chamber. Intraocular pressure (IOP) increased to 62 mmHg. Mannitol
and a topical dorzolamide / timolol were used to control the increase in IOP. The hyphaema slowly resolved over the
following week without sequelae. This case revealed that massive hyphaema can complicate laser iridotomy in patients on
dual antiplatelet therapy, although this is rare. Therefore, if patients are taking aspirin and ticagrelor, it would be advisable
to stop the second medication if possible. In addition, sequential application of photocoagulation and photodisruption
lasers might diminish the risk of significant bleeding.
Journal Article
Flipping the Switch
JOHN SANTORA, HEAD OF asset services at property manager Cushman & Wakefield Inc., admits to being in the dark when it comes to buying electricity. With the first round of electrical power deregulation in New York City over, it's not a good place to be.
Journal Article
Finding gamma ray bursts at high energies and testing the constancy of the speed of light
2008
This dissertation presents the development of algorithms for the LAT Onboard Science Processing as well as an analysis methodology for determining non-constancy in the speed of light at high energy. The main goal of Onboard Science is to find GRBs in real time onboard the LAT. Detailed studies of the expected performance and documentation of the implementation are provided. Given current knowledge and reasonable assumption on the high energy spectra, the expected number of GRBs that will be observed is 1–2 per month at better than 1° of accuracy. Studies presented here map out the performance as a function of GRB parameters. The second part of this thesis focuses on showing that the LAT is sensitive to a Quantum Gravity time delay induced by physics at the Planck scale. Quantitatively, the LAT can distinguish time delays of [special characters omitted](10−5) s/MeV.
Dissertation