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"Gabrys, Barbara J"
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How to succeed as a scientist : from postdoc to professor
\"This unique, practical guide for postdoctoral researchers and graduate students explains how to build and perfect the necessary research tools and working skills to build a career in academia and beyond. It is based on successful training workshops run by the authors: first, it describes the tools needed for independent research, from writing papers to applying for academic jobs; it then introduces skills to thrive in a new job, including managing and interacting with others, designing a taught course and giving a good lecture; and it concludes with a section on managing your career, from how to manage stress to understanding the higher education system. Packed with helpful features encouraging readers to apply the theory to their individual situation, the book is also illustrated throughout with real-world case studies to enable readers to learn from others' experience. It is a vital handbook for everyone seeking to make a successful scientific career\"-- Provided by publisher.
Book
Cognitive Apprenticeship
In recent years, the limited number of places available in academia for new PhDs has changed the way that academics train their successors (Park, 2005). The tension between the necessity of providing a succession of academics who continue research and equipping them with other than research skills was captured in the Roberts UK report (Roberts, 2002: 111): 'the problem [is] that skills acquired by PhD graduates do not serve their long-term needs. Currently, PhDs do not prepare people adequately for careers in business or academia. In particular, there is insufficient access to training in interpersonal and communication skills, management and commercial awareness.' In recent years, research into the doctorate has shown that policy has changed according to new evidence about the career path. In the UK, for example, 54 per cent of doctoral graduates are employed in jobs outside higher education in sectors including healthcare, engineering, finance, statistical professions and wider business and industry; the percentage of UK doctoral graduates working in commercial, industrial and public sector management roles increased from 7 per cent shortly after graduating to 11 per cent three and a half years later; 94 per cent of doctoral graduates use their research skills in their job with at least 40 per cent conducting research most of the time; and 92 per cent of graduates feel that their doctorate has enabled them to be innovative in the workplace (Barber et al., 2004; Fearn, 2010; Hunt et al., 2010). In other words, employers are seeking graduates who can quickly fit in to their organisation, produce added value for their employer, and who are flexible and adapt easily.
Book Chapter
Dynamics of Polymers
This chapter contains sections titled:
Basics of Inelastic and Quasi‐Elastic Neutron Scattering
Characteristic Features of Inelastic and Quasi‐Elastic Neutron Scattering for Polymer Studies
Studies of Dynamics of Polymers
Conclusion
References
Book Chapter
Safety and Feasibility of Radiation Therapy Combined with CDK 4/6 Inhibitors in the Management of Advanced Breast Cancer
The addition of CDK4/6 inhibitors to endocrine therapy in advanced hormone receptor-positive HER2-negative breast cancer has led to practice-changing improvements in overall survival. However, data concerning the safety of CDK4/6i combination with radiotherapy (RT) are conflicting. A retrospective evaluation of 288 advanced breast cancer patients (pts) treated with CDK4/6i was performed, and 100 pts also received RT. Forty-six pts received 63 RT courses concurrently and fifty-four sequentially before CDK4/6i initiation (76 RT courses). Neutropenia was common (79%) and more frequent during and after concurrent RT than sequential RT (86% vs. 76%); however, CDK4/6i dose reduction rates were similar. In patients treated with CDK4/6i alone, the dose reduction rate was 42% (79 pts) versus 38% with combined therapy, and 5% discontinued treatment due to toxicity in the combined group. The risk of CDK4/6i dose reduction was correlated with neutropenia grade, RT performed within the first two CDK4/6i cycles, and more than one concurrent RT; a tendency was observed in concurrent bone irradiation. However, on multivariate regression analysis, only ECOG 1 performance status and severe neutropenia at the beginning of the second cycle were found to be associated with a higher risk of CDK4/6i dose reduction. This largest single-center experience published to date confirmed the acceptable safety profile of the CDK4/6i and RT combination without a significantly increased toxicity compared with CDK4/6i alone. However, one might delay RT for the first two CDK4/6i cycles, when myelotoxic AE are most common.
Journal Article