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The world of sensors is diverse and is advancing at a rapid pace due to the fact of its high demand and constant technological improvements. Electrochemical sensors provide a low-cost and convenient solution for the detection of variable analytes and are widely utilized in agriculture, food, and oil industries as well as in environmental and biomedical applications. The popularity of electrochemical sensing stems from two main advantages: the variability of the reporting signals, such as the voltage, current, overall power output, or electrochemical impedance, and the low theoretical detection limits that originate from the differences in the Faradaic and nonFaradaic currents. This review article attempts to cover the latest advances and applications of electrochemical sensors in different industries. The role of nanomaterials in electrochemical sensor research and advancements is also examined. We believe the information presented here will encourage further efforts on the understanding and progress of electrochemical sensors.

The use of tailored medication delivery in cancer treatment has the potential to increase efficacy while decreasing unfavourable side effects. For researchers looking to improve clinical outcomes, chemotherapy for cancer continues to be the most challenging topic. Cancer is one of the worst illnesses despite the limits of current cancer therapies. New anticancer medications are therefore required to treat cancer. Nanotechnology has revolutionized medical research with new and improved materials for biomedical applications, with a particular focus on therapy and diagnostics. In cancer research, the application of metal nanoparticles as substitute chemotherapy drugs is growing. Metals exhibit inherent or surface-induced anticancer properties, making metallic nanoparticles extremely useful. The development of metal nanoparticles is proceeding rapidly and in many directions, offering alternative therapeutic strategies and improving outcomes for many cancer treatments. This review aimed to present the most commonly used nanoparticles for cancer applications.

Power electronic systems have a great impact on modern society. Their applications target a more sustainable future by minimizing the negative impacts of industrialization on the environment, such as global warming effects and greenhouse gas emission. Power devices based on wide band gap (WBG) material have the potential to deliver a paradigm shift in regard to energy efficiency and working with respect to the devices based on mature silicon (Si). Gallium nitride (GaN) and silicon carbide (SiC) have been treated as one of the most promising WBG materials that allow the performance limits of matured Si switching devices to be significantly exceeded. WBG-based power devices enable fast switching with lower power losses at higher switching frequency and hence, allow the development of high power density and high efficiency power converters. This paper reviews popular SiC and GaN power devices, discusses the associated merits and challenges, and finally their applications in power electronics.

The surge in electric vehicles (EVs) and their electrical appliances requires highly efficient, lightweight electrical machines with better performance. However, conventional wire used for electrical machine windings have certain limits to the current requirements. Copper is a commonly used material in electrical windings, and due to its ohmic resistance, it causes 75% of total losses in electrical machines (copper losses). The high mass of the copper results in a bulky system size, and the winding temperature of copper is always maintained at less than 150 °C to preserve the thermal insulation of the electric machine of the windings. On the other hand, carbon nanotubes and carbon nanotube materials have superior electrical conductivity properties and mechanical properties. Carbon nanotubes ensure 100 MS/m of electrical conductivity, which is higher than the copper electrical conductivity of 59.6 MS/m. In the literature, various carbon nanotubes have been studied based on electrical conductivity, temperature co-efficient with resistivity, material thickness and strength, insulation, and efficiency of the materials. Here, we review the electrical and mechanical properties of carbon nanotubes, and carbon nanotube composite materials are reviewed with copper windings for electrical wires.

We propose a device for monitoring the number of people who are physically present inside indoor environments. The device performs local processing of infrared array sensor data detecting people’s direction, which allows monitoring users’ occupancy in any space of the building and also respects people privacy. The device implements a novel real-time pattern recognition algorithm for processing data sensed by a low-cost infrared (IR) array sensor. The computed information is transferred through a Z-Wave network. On-field evaluation of the algorithm has been conducted by placing the device on top of doorways in offices and laboratory rooms. To evaluate the performance of the algorithm in varying ambient temperatures, two groups of stress tests have been designed and performed. These tests established the detection limits linked to the difference between the average ambient temperature and perturbation. For an in-depth analysis of the accuracy of the algorithm, synthetic data have been generated considering temperature ranges typical of a residential environment, different human walking speeds (normal, brisk, running), and distance between the person and the sensor (1.5 m, 5 m, 7.5 m). The algorithm performed with high accuracy for routine human passage detection through a doorway, considering indoor ambient conditions of 21–30 °C.

Our research aims to achieve dual-positive effects in the presented study by raising photovoltaic (PV) panels over the water surface. With this, target experiments were primarily conducted to evaluate the efficiency increments of the PV panel while reducing its operating temperature through passive convective cooling obtained by raising it over water. The following objective was to estimate the reduction in water evaporation due to the shading effect induced by the panel placed inside the same basin. The performance of two PV panels was analyzed, one used for tests, the other as a reference. The characteristic curves were determined under the local environmental conditions of Cagliari, Italy. The true temperature reduction and efficiency gain calculations of panel P1 due to water cooling was achieved via the measured temperatures and calculated efficiencies of panel P2 at environmental conditions. The water height inside the basin was constantly monitored and maintained at approximately 7.5 cm below panel P1, which covered about 17% of the total water surface area. The presence of water underneath P1 leads to its efficiency increment on average by 2.7% (absolute) and about 17.22% (relative). At the same time, temperature of panel P1 dropped by 2.7 °C on average. The comparative water evaporation study conducted with and without P1 inside the basin showed a 30% reduction in water evaporation.

Antibiotic resistance is one of the main public health concerns of this century. This resistance is also associated with oxidative stress, which could contribute to the selection of resistant bacterial strains. Bearing this in mind, and considering that flavonoid compounds are well known for displaying both activities, we investigated a series of hydroxy-3-arylcoumarins with structural features of flavonoids for their antibacterial activity against different bacterial strains. Active compounds showed selectivity against the studied Gram-positive bacteria compared to Gram-negative bacteria. 5,7-Dihydroxy-3-phenylcoumarin (compound 8) displayed the best antibacterial activity against Staphylococcus aureus and Bacillus cereus with minimum inhibitory concentrations (MICs) of 11 μg/mL, followed by Staphylococcus aureus (MRSA strain) and Listeria monocytogenes with MICs of 22 and 44 μg/mL, respectively. Moreover, molecular docking studies performed on the most active compounds against Staphylococcus aureus tyrosyl-tRNA synthetase and topoisomerase II DNA gyrase revealed the potential binding mode of the ligands to the site of the appropriate targets. Preliminary structure–activity relationship studies showed that the antibacterial activity can be modulated by the presence of the 3-phenyl ring and by the position of the hydroxyl groups at the coumarin scaffold.

Skin aging is a progressive biological process of the human body, and it is not only time-dependent. Differently substituted 3-phenylcoumarins proved to efficiently inhibit tyrosinase. In the current work, new substitution patterns have been explored, and the biological studies were extended to other important enzymes involved in the processes of skin aging, as elastase, collagenase and hyaluronidase. From the studied series, five compounds presented inhibitory activity against tyrosinase, one compound against elastase, eight compounds against collagenase and two compounds against hyaluronidase, being five compounds dual inhibitors. The 3-(4′-Bromophenyl)-5,7-dihydroxycoumarin (1) and 3-(3′-bromophenyl)-5,7-dihydroxycoumarin (2) presented the best profiles against tyrosinase (IC50 = 1.05 µM and 7.03 µM) and collagenase (IC50 = 123.4 µM and 110.4 µM); the 3-(4′-bromophenyl)-6,7-dihydroxycoumarin (4) presented a good inhibition against tyrosinase and hyaluronidase; the 3-(3′-bromophenyl)-6,7-dihydroxycoumarin (5) showed an effective tyrosinase and elastase inhibition; and 6,7-dihydroxy-3-(3′-hydroxyphenyl)coumarin (11) presented a dual profile inhibition against collagenase and hyaluronidase. Furthermore, considering the overall activities tested, compounds 1 and 2 proved to be the most promising anti-aging compounds. These compounds also showed to have a photo-protective effect, without being cytotoxic to human skin keratinocyte cells. To predict the binding site with the target enzymes, computational studies were also carried out.

Energy and water poverty are two main challenges of the modern world. Most developing and underdeveloped countries need more efficient electricity-producing sources to overcome the problem of potable water evaporation. At the same time, the traditional way to produce energy/electricity is also responsible for polluting the environment and damaging the ecosystem. Notably, many techniques have been used around the globe, such as a photovoltaic (PV) cooling (active, passive, and combined) process to reduce the working temperature of the PV panels (up to 60 °C) to improve the system efficiency. For floating photovoltaic (FPV), water cooling is mainly responsible for reducing the panel temperature to enhance the production capacity of the PV panels, while the system efficiency can increase up to around 30%. At the same time, due to the water surface covering, the water loss due to evaporation is also minimized, and the water evaporation could be minimized by up to 60% depending on the total area covered by the water surfaces. Therefore, it could be the right choice for generating clean and green energy, with dual positive effects. The first is to improve the efficiency of the PV panels to harness more energy and minimize water evaporation. This review article focuses mainly on various PV and FPV cooling methods and the use and advantages of FPV plants, particularly covering efficiency augmentation and reduction of water evaporation due to the installation of PV systems on the water bodies.

In this paper, we present the final results from the research project “Urban Abacus of Building Energy Performances (Abaco Urbano Energeticodegli Edifci–AUREE)” aimed at supporting the renovation process and energy efficiency enhancement of urban building stocks. The crux of the AUREE project is a Web–GIS GeoBlog portal with customized semantic dashboards aimed at sharing information on an urban built environment and promoting the participation of local stakeholders in its improvement. As the latest development of this research, a workflow that integrates the AUREE portal with BIM authoring and an open-source IoT platform is implemented and applied to an experimental case study concerning a public building in Carbonia (Italy). The headquarters of the Sotacarbo Sustainable Energy Research Center was selected as the case study. The presented results proved that it was possible to create a valid open system, which was accessible to both specialist and unskilled users, and aimed at guiding, through a progressive knowledge deepening, common end-users toward proper conscious “energy behaviors” as well as public administrations and decision-makers toward sustainable facility management. Later, the proposed open system could also be suitable to be used as an effective tool to support the rising “energy communities”.