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\"Fortunately for those with celiac disease or gluten-intolerance or sensitivity, gluten-free foods are becoming much more readily available at grocery stores and restaurants across the country. However, many prepackaged options are laden with sugar, unhealthy fats, and grains and starches that are devoid of nutritional value. They may be \"safe\" for those who can't eat gluten, but they're far from healthy. In Healthy Gluten-Free Diet, Gehring provides more than 100 recipes that are safe for those on a gluten-free diet, healthy for anyone, and delicious for the whole family! Recipes include: Pumpkin curry Wholesome chocolate chip cookies Pear and pancetta salad Kale, sausage, and risotto soup Almond cake with citrus glaze Wholegrain banana pancakes Hot artichoke dip with flaxseed crackers Chicken skewers with peanut sauce Salmon with coconut quinoa Breakfast burritos with homemade salsa and guacamole And many more! Also included is a guide to grains, helpful baking tips, and tips and instructions for grinding whole grains and growing healthy sprouts right in your kitchen. Gehring provides several recipes for mixes and meals that can be prepared ahead of time and served with minimal preparation for quick, healthy, and delicious meals\"-- Provided by publisher.

Background/Aims Since the emergence of generative AI (GenAI) in fall 2022, its impact on higher education has been significant yet under‐researched, leading to mixed reactions among nurse educators, ranging from enthusiasm to skepticism. A preliminary search of seven databases found no scoping reviews specifically that addressed nurse educators' concerns about using GenAI. Therefore, this study aims to map the existing literature on nurse educators' concerns regarding the use of GenAI in nurse education. Inclusion Criteria Included are any types of sources (peer‐reviewed and nonpeer‐reviewed) in English and from any country and were authored by an academic nurse educator that reported on “academic nurse educators,” and “artificial intelligence” (such as GenAI, Generative AI, ChatGPT, large language models) in nursing education. Articles that did not report “nurse educator concerns,” or were focused on clinical practice were excluded. Methods This protocol (see PRISMA‐P in Appendix 1) establishes the study parameters for the planned scoping review, which will be conducted from April to July 2024. We will follow Joanna Briggs Institute, a comprehensive methodology, to ensure a rigorous approach. The final review will include relevant literature from eight academic databases published from Fall 2022 through April 2024. Data will be reported using the PRISMA‐ScR checklist and flow diagram (2020) along with other visual diagrams to add validity to our findings. An inductive analysis approach will be used to code the evolving data, identify recurring themes, and pinpoint potential gaps in the literature. Results The final scoping review will present the search results, the study inclusion process, and the data analysis. Conclusion Our planned review will potentially provide crucial insights into nurse educators' concerns on using GenAI, pinpointing gaps within the literature, and providing direction for future research. Review Registration This protocol was registered on May 8, 2024, on Open Science Framework (OSF). The registry number is OSF.IO/SZ8WR. This registration ensures the transparency and credibility of our research process, as it provides a public record of our study design and methods.

The objective of this study was to investigate the effects of carprofen administered immediately before cautery dehorning on nociception and stress. Forty Holstein calves aged approximately 6 to 8 wk old were either placebo treated and sham dehorned ( = 10) or cautery dehorned following administration of carprofen (1.4 mg/kg) subcutaneously ( = 10) or orally ( = 10) or a subcutaneous and oral placebo ( = 10) in a randomized, controlled trial. All animals were given a cornual nerve block using lidocaine before dehorning. Response variables including mechanical nociception threshold, ocular temperature, heart rate, and respiratory rate were measured before and following cautery dehorning for 96 h. Blood samples were also collected over 96 h following dehorning and analyzed for plasma cortisol and substance P concentrations by RIA. Plasma carprofen concentration and ex vivo PGE concentrations were also determined for this time period. Average daily gain was calculated for 7 d after dehorning. Data were analyzed using a linear mixed effects model with repeated measures, controlling for baseline values by their inclusion as a covariate in addition to planned contrasts. Dehorning was associated with decreased nociception thresholds throughout the study and a stress response immediately after dehorning, following the loss of local anesthesia, and 48 h after dehorning compared with sham-dehorned calves. Carprofen was well absorbed after administration and reached concentrations that inhibited ex vivo PGE concentrations for 72 h (subcutaneous) and 96 h (oral) compared with placebo-treated calves ( < 0.05). Carprofen-treated calves tended to be less sensitive ( = 0.097) to nociceptive threshold tests. Overall, at the dosing regimen studied, the effect of carprofen on sensitivity and stress following cautery dehorning was minimal. Consideration of route of administration and dose determination studies may be warranted.

This study examined the pharmacokinetics and analgesic effect of oral meloxicam (MEL) administered alone or in combination with gabapentin (GABA) in an experimental bovine lameness model. Eighteen male British × Continental beef calves aged 4 to 6 mo and weighing 297 to 392 kg were randomly assigned to receive either 1) 0.5 mg/kg lactose monohydrate placebo (PLBO; n = 6), 2) 0.5 mg/kg MEL (n = 6), or 3) 0.5 mg/kg MEL combined with 15 mg/kg GABA (MEL-GABA; n = 6) once daily for 4 d. The first treatment was administered 4 h after a chemical synovitis/arthritis was induced with injection of 15 mg amphotericin B into the left hind lateral distal interphalangeal joint. Changes in activity were evaluated continuously with pedometers. Contact force, contact area, contact pressure, impulse, and stride length were recorded once daily with a pressure mat and visual lameness scores were determined by a masked observer using a 5-point scale. Cortisol and drug concentrations were determined daily by immunoassay and HPLC-mass spectrometry, respectively. Outcomes were compared statistically using a random effects mixed model and analysis of covariance. There was a positive association between lameness scores and serum cortisol concentrations (P = 0.02) and a negative association between lameness score and step count (P < 0.0001), total force (P = 0.001), force applied to the lateral claw (P = 0.02), contact pressure (P = 0.005), and impulse of the lateral claw (P = 0.01). Step count was greater in MEL calves compared with PLBO (P = 0.008) and MEL-GABA (P = 0.04) calves. Impulse was greater in the MEL-GABA calves compared with the PLBO calves (P = 0.03). There was an inverse relationship between plasma MEL concentrations and lameness score (P = 0.02) and a positive association between MEL concentrations and force applied to the lateral claw (P = 0.03), total contact pressure (P = 0.03), and impulse on the lateral claw (P = 0.02). There was a tendency towards a positive association between GABA concentrations, total impulse, and impulse on the lateral claw (P = 0.08) and a negative associate between GABA concentrations and step count (P = 0.08). The results of this study suggest that MEL administered alone or in combination with GABA reduced the severity of lameness in calves following induction of lameness with amphotericin B. These findings have implications for developing analgesic protocols in lame calves that address both production and welfare concerns.

Background Generative artificial intelligence (GenAI) has greatly affected higher education since its release in 2022. Academic nurse educators are being called to implement GenAI; however, some have concerns. This article sought to identify and describe the existing evidence on nurse educators' perceived concerns regarding the use of GenAI in nurse education. Method This scoping review was conducted using the Joanna Briggs Institute Methodology and reported using PRISMA-ScR guidelines; a total of736 articles from eight databases were reviewed. Thirty articles met the inclusion criteria. Data were extracted using an author-created Data Extraction Instrument, and thematic analysis was performed. Results Included are 25 sources on the theme of technical factors and subthemes of data inaccuracy, data bias, access inequity, privacy and confidentiality breach, lack of policies and guidelines, and faculty workload. Conclusion As nursing education continues to become more technology-driven, educators need to receive professional development training on its use in nursing programs.

High heat flux and radio blackout are well-known challenges space vehicles have been facing during re-entry into a planet’s atmosphere since the early days of space-flight. Thermal protection systems have been developed to protect spacecraft and astronauts, however, they are often heavy and some have to be replaced after each mission. High temperatures in the compressed gas in the shock wave lead to partial ionization. The dense plasma can cause radio blackout, i.e. attenuation or reflection of radio waves thus blocking data-telemetry and communication with ground stations or satellites. One approach to solve both problems is to influence the plasma with magnetohydrodynamic effects using a strong magnet. In the framework of the European project MEESST (Magnetohydrodynamic Enhanced Entry System for Space Transportation) heat flux mitigation and radio blackout mitigation is investigated by means of modelling and ground experiments in plasma wind tunnels at the Institute of Space Systems (Stuttgart, Germany) and at the Von Karman Institute for Fluid Dynamics (Brussels, Belgium) using an HTS magnet. After a short introduction to the scientific background of the MEESST project, the boundary conditions for the design of the magnet and calculations of field distributions are presented. The pancake coils of the magnet were wound with a robotic winding system. Results from a preliminary test of the conduction-cooled magnet are presented.

A low-weight, compact, tunable phase shifter based on liquid crystal technology is presented. It is designed in a hollow waveguide topology with a dielectric filled cross-section. The operational frequency range is 21–29 GHz, but data up to 35 GHz have been obtained and are presented. The device offers more than 140° phase shift peak per dB insertion loss and 110–130°/dB in the desired range.

The effects of titanium dioxide coatings of bovine hides on light absorption and transdermal transfer of light-derived heat were investigated. Four hair-on rug hides from Holstein cattle were purchased. Twelve samples about 20 cm on a side were cut from each hide; nine from the black-colored areas, and three from the white areas. Samples were randomized and assigned to four coating treatments: (1) white hide with no coating (White), (2) black hide with no coating (Black), (3) black hide with 50% coating (Mid), and (4) black hide with 100% coating (High). Coatings were applied to the black hide samples using a hand sprayer. Lux measurements were taken using a modified lux meter at three light intensities generated with a broad spectrum, cold halogen light source. Reflectance over a wavelength range of 380 to 900 nm was measured using a spectroradiometer. The transdermal transfer of heat derived from absorbed light was measured by applying a broad spectrum, cold halogen light source to the stratum corneum (coated) side of the sample and recording the temperature of the dermis-side using a thermal camera for 10 min at 30-s intervals. At the high light level, the White, Black, Mid, and High coating treatments had different ( P  < 0.001) lux values of 64,945, 1741, 15,978, and 40,730 lx, respectively. In the visible wavelength range (400 to 750 nm), Black hides reflected 10 to 15% of the light energy, hides with the Mid coating treatment reflected 35 to 40%, and hides with the High coating treatment reflected 70 to 80% of the light energy. The natural White hide samples reflected 60 to 80% of the light energy. The average maximum temperatures at the dermis-side of the hides due to transferred heat were 34.5, 70.1, 55.0, and 31.7, for the White, Black, Mid, and High treatments, respectively. Reflective coatings containing titanium dioxide on cattle hides were effective in reducing light energy absorption and reduced light-derived heat transfer from the skin surface to deeper skin layers.

The tetracyclines (TTC) and sulfonamides are among the most common residues found in bulk raw milk samples. Detection of drug residues in bulk milk (BM) tankers demonstrates that the product is not suitable for human consumption. Discarding BM with residue-contaminated milk is a waste of a valuable commodity, and a repurposing for consumption at calf ranches is a way to recapture some value. However, if calves consuming milk with drug residues are slaughtered for veal, their meat could contain drug residues. The objective of this review is to provide a residue avoidance strategy for TTC and sulfonamide residues in veal. To determine the pharmacokinetic properties of each drug a structured review of the literature was performed and the study inclusion criteria were that the publication used dairy breed calves, with body weight <330 kg or <6 months of age. The most pertinent parameters were determined to be plasma, tissue elimination half-lives, and systemic bioavailability. The results of this review were integrated with milk and tissue testing levels of quantification and tissue tolerances to formulate a recommended withdrawal interval for calves ingesting this milk. The suggested withdrawal interval of 20 days will ensure that no veal calves will test positive for residues from being fed this milk.

This study examined the efficacy of sodium salicylate for providing analgesia in an amphotericin B-induced bovine synovitis-arthritis model using 10 male Holstein calves, 4 to 6 mo old and weighing approximately 250kg. The study used a repeated measures partial crossover design with 2 phases, consisting of 3 treatment periods within each phase. Calves were blocked by body weight and randomly assigned to the sodium salicylate (50 mg/kg i.v.) or placebo group for phase 1. In period 1, lameness induction was simulated with a needle prick of the coronary band, followed by drug or placebo administration. At predetermined time points, serial blood samples for cortisol and salicylate concentrations, electrodermal activity measurements, heart rates, and pressure mat data were collected. Visual lameness scores were recorded by an observer blinded to treatments. In period 2, lameness was induced with injection of amphotericin B into the distal interphalangeal joint, followed by drug or placebo administration, with sample collection as described previously. In period 3, the drug or placebo was administered to the respective calves with sample collection. After a 10-d washout period, phase 2 was conducted with treatments crossed over between groups. Cortisol and salicylate samples were analyzed by competitive chemiluminescent immunoassay and fluorescence polarization immunoassay, respectively. The pharmacokinetic data were analyzed using compartmental analysis. Mean intravenous salicylate apparent volume of distribution was 0.2±0.005 L/kg, total body clearance was 4.3±0.2 mL/min·kg, and elimination half-life was 36.9±1.2min. The repeated measures data were analyzed based on a univariate split-plot approach with a random effects-mixed model. Differences in stance phase duration and serum cortisol concentration values were seen both between periods and between treatment group×periods; differences in heart rate, contact surface area, and contact pressure values were seen between periods, suggesting that our lameness model was effective. No differences were seen between treatment groups. When analyzed by visual lameness score, differences were seen in heart rate, contact surface area, contact pressure, and cortisol concentrations. Area under the time-effect curves, determined by using the trapezoidal rule, had results similar to the repeated measures data, except for a difference in period for electrodermal activity. This amphotericin B-induced synovitis-arthritis model is a useful tool for studying changes associated with lameness in cattle. Sodium salicylate was not effective in providing analgesia after lameness.