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"George, Roy"
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Is partial pulpotomy in cariously exposed posterior permanent teeth a viable treatment option?
2020
Data sources PubMed, ScienceDirect and Cochrane, Open Grey. Journal of Dentistry; Journal of Endodontics; International Endodontic Journal; Australian Endodontic Journal; and Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and EndodonticsStudy selection Two independent reviewers screened the titles, abstracts and/or full-text for randomised clinical trials and prospective clinical studies dealing with the success rate of treating cariously exposed vital human permanent posterior teeth with a partial pulpotomy. The cases were followed up for 6 to 24 months.Results The study included five randomised clinical trials and six prospective studies. The pooled data indicated that partial pulpotomy in carious exposed teeth had a success rate of 98%, 96% and 92% after 6 months and 1 and 2 years of follow-up. However, teeth with a presumptive diagnosis of irreversible pulpitis displayed significantly lower success rates. Interestingly, neither the pulp capping material used nor the status of the root apex (apical root closure) or age of the patient affected the treatment success rate.Conclusion The study reported high 2 year success rates when cariously exposed permanent posterior teeth were treated using a partial pulpotomy procedure.
Journal Article
The Avengers. Kree/Skrull War
When Ronan the Accuser seizes control of the Kree Empire and launches an attack against Earth, the Avengers must face the threat, while the shape-shifting Skrulls, hiding among the human population, reveal themselves to wage war.
Efficacy of photobiomodulation on accelerating bone healing after tooth extraction: a systematic review
by
Meer, Mohammed
,
Kulkarni, Sachin
,
Roy, George
in
Biocompatibility
,
Biomedical materials
,
Bone density
2019
Post-extraction healing of the socket may take up to 24 weeks to complete. This systematic review aims to evaluate whether photobiomodulation accelerates bone healing in those sockets. A search strategy was developed in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. PubMed, Cochrane Library, and Scopus electronic databases were searched for in vivo studies with restrictions on the year (< 50 years old) and language (English). After applying the inclusion criteria, ten studies were selected for review. Test subjects included humans (3), rats (5), and rabbits (2), either healthy or with specified systemic condition(s). Laser parameters applied varied between studies significantly. Six studies measured bone density or bone trabeculae percentage, while remaining studies measured secondary outcome measures such as osteogenesis markers, patient’s self-reported pain scores, and clinical epithelial regeneration. No side effects of photobiomodulation have been reported. Higher concentration of osteogenesis markers Ocn and Runx2 were consistently reported across studies, as well as higher percentage of bony trabeculae and bone density. Within the limitations of this review, improvement in bone repair can be found when using photobiomodulation in extraction sockets.
Journal Article
Batman and the Outsiders
by
Barr, Mike W., writer
,
Wolfman, Marv, writer
,
Aparo, Jim, artist
in
COMICS & GRAPHIC NOVELS - Superheroes.
2017
\"In these tales from the 1980s, Batman splits off from the Justice League of America to form his own super-team known as the Outsiders. Including established heroes Black Lightning and Metamorpho as well as dynamic new heroes Katana, Geo-Force, and Halo, the team fought for justice on an international stage. Combining superhero action with espionage, the Outsiders brought their own brand of justice to Geo-Force's nation of Markovia, Katana's homeland of Japan, and across the globe.\"-- Provided by publisher.
The effect of photobiomodulation on human dental pulp–derived stem cells: systematic review
by
Meer, Mohammed
,
George, Roy
,
Kulkarni, Sachin
in
Bias
,
Biomedical materials
,
Cell Differentiation
2020
This systematic review assessed if photobiomodulation of human dental pulp tissue improved cell viability, proliferation, and/or differentiation compared with a placebo. This systematic review was conducted in line with PRISMA. PICO question was established; inclusion and exclusion criteria were established before a search had begun. A literature search was conducted through PubMed, Scopus, and Cochrane. Studies were included if published within the last 20 years in English language, or where translation was available; laser parameters were mentioned; human dental pulp tissue was studied in vitro. Studies were excluded if non-human dental pulp tissue was studied and where the study was an in vivo study. Out of the total 121 studies found, 109 were excluded. Of the twelve included studies, three full-text articles were not available despite attempts made to contact the respective authors, leaving nine studies. Four of the included studies reported the use of stem cells derived from human deciduous teeth (SHEDs), and five used those from human permanent teeth (DPSCs). Most included studies utilized InGaAlP laser with wavelengths 660 nm, and one study with 610 nm. Other types of lasers included LED InGaN, and GaAlAs. Out of all included studies, two had a moderate risk of bias, and the rest had a low risk of bias. All studies confirmed positive effects on proliferation. One study also found improved osteogenic differentiation of the stem cells derived from stem cells of deciduous teeth. After assessing SHEDs and DPSCs separately, it is found that photobiomodulation improved cell proliferation in both subgroups. Due to heterogeneity in design protocols and laser parameters, it was not possible to compare the studies together. However, this study indicated that cell viability and proliferation did improve with photobiomodulation.
Journal Article
What is the evidence of outcomes of endodontically treated cracked teeth?
2021
Data sources Ovid, PubMed and Cochrane were searched using the indexed terms. Additional searches were made using endodontic textbooks and endodontic-related journals.Study selection Two independent reviewers screened the titles, abstracts and/or full text for clinical studies evaluating the treatment outcomes of healthy patients over 18 years of age who received root canal treatment with at least one year in occlusal function.Results The study included four articles and reported an overall survival of 84% after 60 months in endodontically treated cracked teeth. The authors reported that teeth with single crack, cracks contained within crowns and teeth with pre-treatment periodontal probing less than 3 mm had a lower risk of being extracted.Conclusion This study reported a moderately high survival rate of endodontically treated cracked teeth.
Journal Article
Evaluation of the evidence of effectiveness of ultrasonic activated irrigation for root canal treatment
2019
Data sources Cochrane Library, Embase, LILACS, PubMed, SciELO, Scopus databases, endodontic journals and textbooks. Study selection Two independent reviewers screened the titles, abstracts and/or full-text of the both clinical or in vitro studies that used ultrasonic irrigant activation for management of teeth needing root canal therapy. Results The study included three clinical studies and 45 in vitro studies. The study reported no evidence of any benefit of ultrasonic activation over needle irrigation in improving the healing rate of apical periodontitis. While the study reported that the evidence for disinfection of the root canal was inconclusive it did show evidence of the efficacy of ultrasonic irrigation over needle irrigation when removal of pulp tissue remnants and hard tissue debris was assessed. Conclusion The study reported that it was essential that there should be more research into the antimicrobial effect on healing in periapical periodontitis when teeth are treated using ultrasonic activation.
Journal Article