Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
6
result(s) for
"Giaimo, Paul"
Sort by:
Ethnic Outsiders: The Hyper-Ethnicized Narrator in Langston Hughes and Fred L. Gardaphé
Giaimo examines another way to characterize ethnic otherness through the use of ethnic humor, an excellent means of coping with the individual experiencing such otherness. He states that in literary terms, the conventions of hyper-ethnicized narrative can be traced across other texts and genres.
Journal Article
Moustache Pete Is Dead: Evviva Baffo Pietro
\"Moustache Pete is Dead: Evviva Baffo Pietro!\" by Fred Gardaphe is reviewed.
Book Review
Radical-Containing Ultrafine Particulate Matter Initiates Epithelial-to-Mesenchymal Transitions in Airway Epithelial Cells
Environmentally persistent free radicals (EPFRs) in combustion-generated particulate matter (PM) are capable of inducing pulmonary pathologies and contributing to the development of environmental asthma. In vivo exposure of infant rats to EPFRs demonstrates their ability to induce airway hyperresponsiveness to methacholine, a hallmark of asthma. However, the mechanisms by which combustion-derived EPFRs elicit in vivo responses remain elusive. In this study, we used a chemically defined EPFR consisting of approximately 0.2 μm amorphrous silica containing 3% cupric oxide with the organic pollutant 1,2-dichlorobenzene (DCB-230). DCB-230 possesses similar radical content to urban-collected EPFRs but offers several advantages, including lack of contaminants and chemical uniformity. DCB-230 was readily taken up by BEAS-2B and at high doses (200 μg/cm(2)) caused substantial necrosis. At low doses (20 μg/cm(2)), DCB-230 particles caused lysosomal membrane permeabilization, oxidative stress, and lipid peroxidation within 24 hours of exposure. During this period, BEAS-2B underwent epithelial-to-mesenchymal transition (EMT), including loss of epithelial cell morphology, decreased E-cadherin expression, and increased α-smooth muscle actin (α-SMA) and collagen I production. Similar results were observed in neonatal air-liquid interface culture (i.e., disruption of epithelial integrity and EMT). Acute exposure of infant mice to DCB-230 resulted in EMT, as confirmed by lineage tracing studies and evidenced by coexpression of epithelial E-cadherin and mesenchymal α-SMA proteins in airway cells and increased SNAI1 expression in the lungs. EMT in neonatal mouse lungs after EPFR exposure may provide an explanation for epidemiological evidence supporting PM exposure and increased risk of asthma.
Journal Article
LETTERS
I am very disturbed by the quoted comments from the unnamed transit police officer in Ray Sanchez' column [\"In the Subways,\" Jan. 18]. The anonymous cop says, \"We're overworked and underpaid. Now you're going to tell me I have to be nice to these people? Come on.\" First, yes, he does have to treat \"these people\" with courtesy and respect. It is a responsibility that comes with the uniform and the badge. Second, \"these people\" are not the ones who determine his workload or his salary. He should blame the politicians, not the citizens whom he is sworn to protect and serve. Supporters of Sen. John Ashcroft's nomination to be attorney general constantly invoke the word \"integrity,\" as if it were somehow unusual for a cabinet member to be honest. But isn't integrity, like experience, simply assumed for any major appointee? More pertinent is the question of judgment: Even honest individuals are capable of bizarre or irrational behavior. Perhaps during his hearings, Ashcroft will be asked to explain why, along with Sen. Jesse Helms, he vigorously opposed the confirmation of James Hormel, an unusually well qualified ambassadorial appointee who happened to be be gay. An honest response to precisely what it is about this decent, honorable man that arouses such animus could go far toward revealing whether Sen. Ashcroft actually possesses either the judgment or the fair-mindedness required of an attorney general.
Newspaper Article