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"Gkentsidi, Theodosia"
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Dermoscopic Clues of Histopathologically Aggressive Basal Cell Carcinoma Subtypes
by
Camela, Elisa
,
Sgouros, Dimitrios
,
Papageorgiou, Chryssoula
in
Basal cell carcinoma
,
Biopsy
,
Dermatology
2023
Background: The group of histopathologically aggressive BCC subtypes includes morpheaform, micronodular, infiltrative and metatypical BCC. Since these tumors are at increased risk of recurring, micrographically controlled surgery is considered the best therapeutic option. Although dermoscopy significantly improves the clinical recognition of BCC, scarce evidence exists on their dermoscopic criteria. Aim: To investigate the dermoscopic characteristics of histopathologically aggressive BCC subtypes. Materials and Methods: Dermoscopic images of morpheaform, micronodular, infiltrative and metatypical BCC were analyzed for the presence of predefined variables. Descriptive and analytical statistics were performed. Results: Most histopathologically aggressive BCCs were located on the head and neck. Infiltrative was the most common subtype. All subtypes, except micronodular BCC, rarely displayed dermoscopic pigmentation. The most frequent dermoscopic features of infiltrative BCC were arborizing vessels (67.1%), shiny white structures (48.6%) and ulceration (52.9%). The features prevailing in morpheaform BCC were arborizing vessels (68.4%), ulceration (n = 12, 63.2%) and white porcelain areas (47.4%). Micronodular BCC was typified by milky red structureless areas (53.8%), arborizing vessels (53.8%), short fine telangiectasias (50%), ulceration (46.2%) and blue structures (57.7%). The most common findings in metatypical BCC were arborizing vessels (77.8%), shiny white structures (66.7%), ulceration (62.9%) and keratin mass (29.6%). Limitations: Study population of only white skin and relatively small sample size in some groups. Conclusions: Our study provided data on the clinical, dermoscopic and epidemiological characteristics of histopathologically aggressive BCCs.
Journal Article
Dermoscopic spectrum of rosacea
by
Errichetti, Enzo
,
Vakirlis, Efstratios
,
Papageorgiou, Chrysa
in
dermoscopy
,
Erythema
,
Genotype & phenotype
2022
Background Rosacea is a chronic inflammatory disease that manifests with various signs and symptoms including erythema, telangiectasias, papules and pustules that mostly affect cheeks, chin, nose and the central forehead. Rosacea is considered as a continuous spectrum that includes different subtypes/phenotypes (erythematotelangiectatic, papulopustular, phymatous), and might also encompass lupus miliaris disseminatus faciei (LMDF) and roasecea‐like demodicosis. Objective To assess the dermoscopic features of the different rosacea subtypes/phenotypes. Methods Patients with a clinical diagnosis of rosacea, confirmed or not by histopathology, or rosacea‐like demodicosis diagnosed by skin scrapings or LMDF diagnosed histopathologically were included. Dermoscopic images were evaluated for the presence of predefined criteria. The selection of dermoscopic variables was based on the International Dermoscopy Society Consensus on standardisation of terminology. Results Eighty‐five patients with facial lesions of rosacea were included in the analysis. Linear reticular vessels in regular distribution were present in the vast majority of the erythematotelangiectatic subtype forming the characteristic pattern of vascular polygons. A similar, but less pronounced, vascular pattern was typified in papulopustular subtype, with the additional presence of follicular plugs and pustules. Phymatous rosacea was characterised by variable morphologic types of vessels in a reticular arrangement, combined with follicular yellow clods. In granulomatous rosacea, focal orange structureless areas were found in all cases and perifollicular orange colour in most of them. In dermoscopy of LMDF, follicular criteria predominated, with perifollicular orange colour and follicular plugs being present in all cases. In demodicosis, the prevailing dermoscopic finding was white mass protruding out of the hair follicle. Conclusion This study suggests that dermoscopy facilitates the recognition of the clinical subtypes/phenotypes of rosacea, enhancing the clinical diagnosis and prompt therapeutic choices. The dermoscopic spectrum of rosacea: Linear reticular vessels in regular distribution typify erythematotelangiectatic rosacea. A similar, but less pronounced, vascular pattern is seen in papulopustular subtype, along with follicular plugs and pustules. Phymatous rosacea displays variable morphologic types of vessels in a reticular arrangement, combined with follicular yellow clods. Granulomatous rosacea exhibits focal orange structureless areas and perifollicular orange colour. Lupus miliaris disseminatus faciei displays perifollicular orange colour and follicular plugs. White masses protruding out of the hair follicle typify demodicosis.
Journal Article