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India is considered a hub for a wide range of phytochemicals due to its rich biodiversity, which indeed flourished with many folk medicines and treatments. Phytochemicals are secondary metabolites synthesized in plants to protect themselves from deteriorating environmental stress and defense against pathogens. In the present study, we aimed to explore the strong anticancer potential of the bioactive compound present in the leaf extract of Coldenia procumbens (L.). The bioactive compound oleanolic acid was first time reported in the plant and was successfully isolated, characterized with various spectroscopic analyses. The in vitro study results explored that oleanolic acid has shown a potent cytotoxic effect against human hepatocellular carcinoma cell lines with a low IC 50 value (40.66μg/mL) and induced apoptotic cell death. Overall, the present findings clearly demonstrated that the natural triterpenoid compound oleanolic acid isolated from C. procumbens showed a potent cytotoxic effect against HepG2 cells and explored the strong anticancer potential against liver cancer.

Brassica oleracea Linn. a dietary rich vegetable with high potential health properties, remarkably its secondary metabolites possessing interesting pharmacological properties. In the twenty-first century, nanoparticles and nano-based biomedical applications play a dominant role in the health sector. Silver nanoparticles are one such metallic nanoparticle that has potential application in the pharma field and act as a potent source against microbial infections. The biosynthesized silver nanoparticles from Brassica oleracea were characterized using various spectroscopy and electron microscopy techniques. Among the diverse secondary metabolites found in Brassica oleracea L., the methanolic extract of the leaf showed the presence of different phytochemical analysis present in the plant sample. Phenolic compounds and flavonoids have received considerable attention for their potent anti-oxidative properties. Based on the quantitative analysis of phytochemical studies, the phenols and flavonoids were found to be in desirable concentrations. Phyto-synthesized silver nanoparticles were visually validated by their color change and confirmed with the spectral analysis by the presence of peak values that matched with the synthesized level of silver nanoparticles. Brassica oleracea leaf extract was screened for its anti-bacterial efficacy and evaluated against Gram-positive and Gram-negative strains using the disc diffusion method. As a result, the phyto-synthesized silver nanoparticles showed promising results against pathogenic bacterial strains.