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"Graham, Jennifer"
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Veronica Mars. The thousand-dollar tan line
\"The first book in an original mystery series featuring twenty-eight-year-old Veronica Mars, back in action after the events of Veronica Mars: The Movie. With the help of old friends--Logan Echolls, Mac Mackenzie, Wallace Fennel, and even Dick Casablancas--Veronica is ready to take on Neptune's darkest cases with her trademark sass and smarts. Final title and cover to be announced\"-- Provided by publisher.
The longitudinal connection between depressive symptoms and inflammation: Mediation by sleep quality
by
Almeida, David M.
,
Song, Sunmi
,
Graham-Engeland, Jennifer E.
in
Biology and Life Sciences
,
Biomarkers
,
C-reactive protein
2022
Although there is a strong association between depressive symptoms and markers of inflammation, it remains unclear whether depressive symptoms at one point in life may predict inflammation later in life. Moreover, despite extant literature linking sleep with both depressive symptoms and inflammation, there is little research investigating poor sleep as a mechanism linking depressive symptoms with later inflammation. The links between depression and physical health can also vary by gender. In longitudinal analyses with data from the Midlife in the United States (MIDUS) study, we examined whether depressive symptoms were associated with inflammatory markers 11 years later and whether these associations were mediated by sleep disturbances or moderated by gender. Participants reported depressive symptoms and demographic information at baseline. At 11-year follow-up, the same participants ( n = 968) reported depressive symptoms, sleep quality and duration using validated scale items, and provided a blood sample from which inflammatory markers interleukin-6 (IL-6) and C-reactive protein (CRP) were quantified. Actigraphy assessment of sleep was obtained in a subsample ( n = 276). After adjusting for concurrent depressive symptoms and other relevant covariates, baseline depressive symptoms were associated with CRP 11 years later in the full sample, and with IL-6 among women. Subjective sleep quality mediated the association between depressive symptoms and CRP. Results suggest that depressive symptoms may be longitudinally associated with inflammation; however, directionality issues cannot be determined from the present work, particularly as inflammation markers (which might have been associated with baseline depressive symptoms) were not available at baseline. Findings further suggest that longitudinal associations between depressive symptoms and inflammation may potentially be explained by sleep and may reflect gender specific patterns.
Journal Article
River Control Points for Algal Productivity Revealed by Transport Analysis
2024
Measurement of planktonic chlorophyll‐a—a proxy for algal biomass—in rivers may represent local production or algae transported from upstream, confounding understanding of algal bloom development in flowing waters. We modeled 3 years of chlorophyll‐a transport through a 394‐km portion of the Illinois River and found that although algal biomass is longitudinally widespread, most net production occurs at river control points in the upper reaches (up to 3.7 Mg chlorophyll‐a y−1 km−1). Up to 69% of the algal biomass in the upper river was a result of within‐reach production, with the remainder recruited from headwaters and tributaries. High chlorophyll‐a measured farther downstream was largely because of transport from source‐area control points, with substantial net losses of algal biomass occurring in the lower river. Modeling the often‐overlooked river transport component is necessary to characterize where, when, and why planktonic algae grow and predict how far and fast they move downstream. Plain Language Summary Planktonic algae in rivers may accumulate during periods of high productivity stimulated by favorable light, temperature, nutrient, and flow conditions, which can disrupt ecological processes and affect human uses including recreation and drinking water supply. Planktonic algae observed in rivers may occur because of local growth or transport from upstream source areas. Therefore, considering both local and upstream conditions may improve early warnings of potentially harmful blooms. Along a 394‐km stretch of the Illinois River, we found that most of the algae grew in the upper reaches and was then transported to downstream reaches, contributing to potential downstream harms such as excessive turbidity, organic carbon, biological oxygen demand, and algal toxins. We demonstrate how the often‐overlooked river transport component can be quantified to better identify where, when, and why algae grow in river networks. Key Points Planktonic algal biomass is pervasive in the Illinois River, yet production is favored at certain locations and times Most planktonic algal biomass was produced in upper‐reach control points that supplied downstream areas Transport analysis using local and upstream data improves understanding of river algal blooms
Journal Article
Veronica Mars. Mr. Kiss and Tell
\"The second Veronica Mars novel, in which she investigates a mysterious crime at The Neptune Grand hotel\" -- Provided by publisher.
Metagenomic mapping of cyanobacteria and potential cyanotoxin producing taxa in large rivers of the United States
by
Linz, David M.
,
Sienkiewicz, Nathan
,
Graham, Jennifer L.
in
631/158/2459
,
631/326/2565/2142
,
631/326/2565/855
2023
Cyanobacteria and cyanotoxin producing cyanobacterial blooms are a trending focus of current research. Many studies focus on bloom events in lentic environments such as lakes or ponds. Comparatively few studies have explored lotic environments and fewer still have examined the cyanobacterial communities and potential cyanotoxin producers during ambient, non-bloom conditions. Here we used a metagenomics-based approach to profile non-bloom microbial communities and cyanobacteria in 12 major U.S. rivers at multiple time points during the summer months of 2019. Our data show that U.S. rivers possess microbial communities that are taxonomically rich, yet largely consistent across geographic location and time. Within these communities, cyanobacteria often comprise significant portions and frequently include multiple species with known cyanotoxin producing strains. We further characterized these potential cyanotoxin producing taxa by deep sequencing amplicons of the
microcystin E
(
mcyE
) gene. We found that rivers containing the highest levels of potential cyanotoxin producing cyanobacteria consistently possess taxa with the genetic potential for cyanotoxin production and that, among these taxa, the predominant genus of origin for the
mcyE
gene is
Microcystis
. Combined, these data provide a unique perspective on cyanobacteria and potential cyanotoxin producing taxa that exist in large rivers across the U.S. and can be used to better understand the ambient conditions that may precede bloom events in lotic freshwater ecosystems.
Journal Article
Correlation between the dome-shaped superconducting phase diagram, charge order, and normal-state electronic properties in LaRu3Si2
by
Luetkens, Hubertus
,
von Rohr, Fabian O.
,
Wehinger, Björn
in
639/301/119/995
,
639/766/119/1003
,
Condensed matter physics
2025
The interplay between superconductivity and charge or spin order is a key focus in condensed matter physics, with kagome lattice systems providing unique insights. The kagome superconductor LaRu
3
Si
2
(
T
c
≃ 6.5 K) features a characteristic kagome band structure and a hierarchy of charge order transitions at
T
co,I
≃ 400 K and
T
co,II
≃ 80 K, along with an additional transition at
T
* ≃ 35 K associated with electronic and magnetic responses. Using magnetotransport under pressure up to 40 GPa, we find
T
c
peaks at 9 K (2 GPa)—the highest among kagome superconductors—remains nearly constant up to 12 GPa, and then decreases to 2 K at 40 GPa, forming a dome-shaped phase diagram. Similarly, both the resistivity anomaly at
T
* and the magnetoresistance exhibit a dome-shaped pressure dependence. Moreover, above 12 GPa, X-ray diffraction reveals that the charge order evolves from long-range to short-range, coinciding with the suppression of
T
c
. These observations indicate that superconductivity in LaRu
3
Si
2
is closely linked to the charge-ordered state and the electronic responses at
T
co,II
and
T
*.
The authors study kagome superconductor LaRu3Si2 under pressure up to 40 GPa. They find a superconducting dome as a function of pressure, with Tc reaching its maximum when the coexisting charge order remains long-range.
Journal Article
Seasonal forecasting of the European North-West shelf seas: limits of winter and summer sea surface temperature predictability
by
Atkins, Jamie R. C.
,
Halloran, Paul R.
,
Scaife, Adam A.
in
Aquaculture
,
Atmosphere
,
Atmospheric circulation
2024
The European North-West shelf seas (NWS) support economic interests and provide environmental services to adjacent countries. Expansion of offshore activities, such as renewable energy infrastructure, aquaculture, and growth of international shipping, will place increasingly complex demands on the marine environment over the coming decades. Skilful forecasting of NWS properties on seasonal timescales will help to effectively manage these activities. Here we quantify the skill of an operational large-ensemble ocean-atmosphere coupled global forecasting system (GloSea), as well as benchmark persistence forecasts, for predictions of NWS sea surface temperature (SST) at 2–4 months lead time in winter and summer. We identify sources of and limits to SST predictability, considering what additional skill may be available in the future. We find that GloSea NWS SST skill is generally high in winter and low in summer. GloSea outperforms simple persistence forecasts by adding information about atmospheric variability, but only to a modest extent as persistence of anomalies in the initial conditions contributes substantially to predictability. Where persistence is low – for example in seasonally stratified regions – GloSea forecasts show lower skill. GloSea skill can be degraded by model deficiencies in the relatively coarse global ocean component, which lacks dynamic tides and subsequently fails to robustly represent local circulation and mixing. However, “atmospheric mode matched” tests show potential for improving prediction skill of currently low performing regions if atmospheric circulation forecasts can be improved. This underlines the importance of coupled atmosphere-ocean model development for NWS seasonal forecasting applications.
Journal Article
Toxic Algae in Inland Waters of the Conterminous United States—A Review and Synthesis
by
Rosen, Barry H.
,
Christensen, Victoria G.
,
Rogosch, Jane S.
in
20th century
,
Algae
,
Aquatic ecosystems
2023
Cyanobacteria are the most common toxigenic algae in inland waters. Their toxins can affect the health of aquatic and terrestrial organisms, including humans. Other algal groups, such as haptophytes (e.g., Prymnesium parvum) and euglenoids (e.g., Euglena sanguinea), can also form harmful algal blooms (HABs) whose toxins cause injury to aquatic biota but currently have no known effects on human health. Prymnesium parvum, however, is responsible for some of the worst HAB-related ecological disasters recorded in inland waters. Here, we provide an overview of the primary toxigenic algae found in U.S. inland waters: cyanobacteria (planktonic forms), P. parvum, and E. sanguinea with the objective of describing their similarities and differences in the areas of HAB ecology, algal toxins, and the potential for future range expansion of HABs. A detailed account of bloom habitats and their known associations with land cover and use is provided from the perspective of water quality. This review revealed that salinity may have an influence on inland cyanobacterial blooms and cyanotoxins that had not been fully recognized previously.
Journal Article