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"Grant, N."
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Leo Strauss and Anglo-American democracy : a conservative critique
\"Interprets Leo Strauss's political philosphy from a conservative standpoint and argues that Strauss was a Cold War liberal. Suggests inattention to Christianity is crucial to the Straussian portrayal of Anglo-American democracy as a universal regime whose eternal ideals of liberty and constitutional governmnent accord with the teachings of Plato and Aristotle, rather than the Gospels\"-- Provided by publisher.
Book
Proof of the weak gravity conjecture from black hole entropy
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bstract
We prove that higher-dimension operators contribute positively to the entropy of a thermodynamically stable black hole at fixed mass and charge. Our results apply whenever the dominant corrections originate at tree level from quantum field theoretic dynamics. More generally, positivity of the entropy shift is equivalent to a certain inequality relating the free energies of black holes. These entropy inequalities mandate new positivity bounds on the coefficients of higher-dimension operators. One of these conditions implies that the charge-to-mass ratio of an extremal black hole asymptotes to unity from above for increasing mass. Consequently, large extremal black holes are unstable to decay to smaller extremal black holes and the weak gravity conjecture is automatically satisfied. Our findings generalize to arbitrary spacetime dimension and to the case of multiple gauge fields. The assumptions of this proof are valid across a range of scenarios, including string theory constructions with a dilaton stabilized below the string scale.
Journal Article
Consistency of the standard model effective field theory
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bstract
We derive bounds on couplings in the standard model effective field theory (SMEFT) as a consequence of causality and the analytic structure of scattering amplitudes. In the SMEFT, there are 64 independent operators at mass dimension eight that are quartic in bosons (either Higgs or gauge fields) and that contain four derivatives and/or field strengths, including both CP-conserving and CP-violating operators. Using analytic dispersion relation arguments for two-to-two bosonic scattering amplitudes, we derive 27 independent bounds on the sign or magnitude of the couplings. We show that these bounds also follow as a consequence of causality of signal propagation in nonvacuum SM backgrounds. These bounds come in two qualitative forms: i) positivity of (various linear combinations of) couplings of CP-even operators and ii) upper bounds on the magnitude of CP-odd operators in terms of (products of) CP-even couplings. We exhibit various classes of example completions, which all satisfy our EFT bounds. These bounds have consequences for current and future particle physics experiments, as part of the observable parameter space is inconsistent with causality and analyticity. To demonstrate the impact of our bounds, we consider applications both to SMEFT constraints derived at colliders and to limits on the neutron electric dipole moment, highlighting the connection between such searches suggested by infrared consistency.
Journal Article
Veneziano variations: how unique are string amplitudes?
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bstract
String theory offers an elegant and concrete realization of how to consistently couple states of arbitrarily high spin. But how unique is this construction? In this paper we derive a novel, multi-parameter family of four-point scattering amplitudes exhibiting i) polynomially bounded high-energy behavior and ii) exchange of an infinite tower of high-spin modes, albeit with a finite number of states at each resonance. These amplitudes take an infinite-product form and, depending on parameters, exhibit mass spectra that are either unbounded or bounded, thus corresponding to generalizations of the Veneziano and Coon amplitudes, respectively. For the bounded case, masses converge to an accumulation point, a peculiar feature seen in the Coon amplitude but more recently understood to arise naturally in string theory [1]. Importantly, our amplitudes contain free parameters allowing for the customization of the slope and offset of the spin-dependence in the Regge trajectory. We compute all partial waves for this multi-parameter class of amplitudes and identify unitary regions of parameter space. For the unbounded case, we apply similar methods to derive new deformations of the Veneziano and Virasoro-Shapiro amplitudes.
Journal Article
Humanism and the Latin classics
Aldus enjoyed widespread fame as a scholar-printer-publisher. Aldus' mission in life was less to display his own erudition than to serve the scholarly needs of his contemporaries, whether they were young students, educated readers, learned academics or distinguished authors. To this end Aldus accomplished much; his contribution to the promotion of classical languages and literature was a considerable one, and was recognized as such by his contemporaries. This volume contains editions of Ancient Latin authors, Humanistic authors, and others.-- Provided by publisher
Book
Accumulation-point amplitudes in string theory
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bstract
We point out some common qualitative features of the Coon amplitude — a family of deformations of the Veneziano amplitude with logarithmic Regge trajectories — and the open string scattering amplitude for strings ending on a D-brane in AdS. Both reduce to the Veneziano amplitude at relatively low energies. Both systems have an accumulation point in their spectrum, with an infinite number of states below a certain energy. The approach to this point is very similar. Both have the same high-energy fixed-angle behavior. Nevertheless, we find some differences in the spectrum of states with highest angular momentum. These similarities suggest that there may exist a string background that realizes the Coon amplitude.
Journal Article
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in inflammation and in vascular biology. The human family includes 19 members that can be sub-grouped on the basis of their known substrates, namely the aggrecanases or proteoglycanases (ADAMTS1, 4, 5, 8, 9, 15 and 20), the procollagen N-propeptidases (ADAMTS2, 3 and 14), the cartilage oligomeric matrix protein-cleaving enzymes (ADAMTS7 and 12), the von-Willebrand Factor proteinase (ADAMTS13) and a group of orphan enzymes (ADAMTS6, 10, 16, 17, 18 and 19). Control of the structure and function of the extracellular matrix (ECM) is a central theme of the biology of the ADAMTS, as exemplified by the actions of the procollagen-N-propeptidases in collagen fibril assembly and of the aggrecanases in the cleavage or modification of ECM proteoglycans. Defects in certain family members give rise to inherited genetic disorders, while the aberrant expression or function of others is associated with arthritis, cancer and cardiovascular disease. In particular, ADAMTS4 and 5 have emerged as therapeutic targets in arthritis. Multiple ADAMTSs from different sub-groupings exert either positive or negative effects on tumorigenesis and metastasis, with both metalloproteinase-dependent and -independent actions known to occur. The basic ADAMTS structure comprises a metalloproteinase catalytic domain and a carboxy-terminal ancillary domain, the latter determining substrate specificity and the localization of the protease and its interaction partners; ancillary domains probably also have independent biological functions. Focusing primarily on the aggrecanases and proteoglycanases, this review provides a perspective on the evolution of the ADAMTS family, their links with developmental and disease mechanisms, and key questions for the future.
Journal Article