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Womens work was a magazine edited by Alison Knowles and Annea Lockwood that featured text-based and instructional performance scores by twenty-five women artists. In the original publication of Issue 1, Nye Ffarrabas appeared as Bici Forbes and Annea Lockwood appeared as Anna Lockwood. In the original publication of Issue 2, Ann Noël appeared as Ann Williams.

Despite broad recognition of the value of social sciences and increasingly vocal calls for better engagement with the human element of conservation, the conservation social sciences remain misunderstood and underutilized in practice. The conservation social sciences can provide unique and important contributions to society's understanding of the relationships between humans and nature and to improving conservation practice and outcomes. There are 4 barriers—ideological, institutional, knowledge, and capacity—to meaningful integration of the social sciences into conservation. We provide practical guidance on overcoming these barriers to mainstream the social sciences in conservation science, practice, and policy. Broadly, we recommend fostering knowledge on the scope and contributions of the social sciences to conservation, including social scientists from the inception of interdisciplinary research projects, incorporating social science research and insights during all stages of conservation planning and implementation, building social science capacity at all scales in conservation organizations and agencies, and promoting engagement with the social sciences in and through global conservation policy-influencing organizations. Conservation social scientists, too, need to be willing to engage with natural science knowledge and to communicate insights and recommendations clearly. We urge the conservation community to move beyond superficial engagement with the conservation social sciences. A more inclusive and integrative conservation science—one that includes the natural and social sciences—will enable more ecologically effective and socially just conservation. Better collaboration among social scientists, natural scientists, practitioners, and policy makers will facilitate a renewed and more robust conservation. Mainstreaming the conservation social sciences willfacilitate the uptake of the full range of insights and contributions from these fields into conservation policy and practice. A pesar del reconocimiento general del valor de las ciencias sociales y los crecientes llamados por un mejor compromiso con el elemento humano de la conservación, las ciencias sociales de la conservación siguen siendo malentendidas y poco utilizadas en la práctica. Las ciencias sociales de la conservación pueden proporcionar contribuciones únicas e importantes para el entendimiento de la sociedad de las relaciones entre los humanos y la naturaleza y para la mejora de las prácticas de la conservación y sus resultados. Existen cuatro barreras - ideológicas, institucionales, de conocimiento y de capacidad - para la integración significativa de las ciencias sociales dentro de la conservación. Proporcionamos una guia práctica sobre cómo sobreponerse a estas barreras paraJncorporar la perspectiva de las ciencias sociales a la ciencia, las prácticas y las políticas de conservación. En general, recomendamos promover el conocimiento sobre el alcance y las contribuciones de las ciencias sociales para la conservación, incluir a los científicos sociales desde el origen de los proyectos de investigación interdisciplinaria, incorporar la investigación de las ciencias sociales y las percepciones durante todas las fases de la planificación y la implementación de la conservación, construir la capacidad de las ciencias sociales en todas las escalas de las organizaciones y agencias de conservación y promover el compromiso con las ciencias sociales en y a través de organizaciones de conservación con influencia política. Los científicos sociales de la conservación, también, necesitan estar dispuestos a involucrarse con el conocimiento de las ciencias naturales y a comunicar percepciones y recomendaciones de manera clara. Le urgimos a la comunidad de la conservación que vaya más allá del compromiso superficial con las ciencias sociales de la conservación. Una ciencia de la conservación más incluyente y integradora - una que incluya a las ciencias sociales y naturales - permitirá una conservación más justa socialmente y más efectiva ecológicamente. Una mejor colaboración entre los científicos sociales, los científicos naturales, los practicantes y quienes elaboran las políticas facilitará una conservación más renovada y más sólida. Incorporar la perspectiva de las ciencias sociales de la conservación facilitará la absorción de la extensión completa de conocimiento y contribuciones de estos campos a la práctica y las políticas de la conservación.

Despite broad recognition of the value of social sciences and increasingly vocal calls for better engagement with the human element of conservation, the conservation social sciences remain misunderstood and underutilized in practice. The conservation social sciences can provide unique and important contributions to society's understanding of the relationships between humans and nature and to improving conservation practice and outcomes. There are 4 barriers--ideological, institutional, knowledge, and capacity--to meaningful integration of the social sciences into conservation. We provide practical guidance on overcoming these barriers to mainstream the social sciences in conservation science, practice, and policy. Broadly, we recommend fostering knowledge on the scope and contributions of the social sciences to conservation, including social scientists from the inception of interdisciplinary research projects, incorporating social science research and insights during all stages of conservation planning and implementation, building social science capacity at all scales in conservation organizations and agencies, and promoting engagement with the social sciences in and through global conservation policy-influencing organizations. Conservation social scientists, too, need to be willing to engage with natural science knowledge and to communicate insights and recommendations clearly. We urge the conservation community to move beyond superficial engagement with the conservation social sciences. A more inclusive and integrative conservation science--one that includes the natural and social sciences--will enable more ecologically effective and socially just conservation. Better collaboration among social scientists, natural scientists, practitioners, and policy makers will facilitate a renewed and more robust conservation. Mainstreaming the conservation social sciences will facilitate the uptake of the full range of insights and contributions from these fields into conservation policy and practice. / Incorporación de la Perspectiva de las Ciencias Sociales a la Conservación Resumen A pesar del reconocimiento general del valor de las ciencias sociales y los crecientes llamados por un mejor compromiso con el elemento humano de la conservación, las ciencias sociales de la conservación siguen siendo malentendidas y poco utilizadas en la práctica. Las ciencias sociales de la conservación pueden proporcionar contribuciones únicas e importantes para el entendimiento de la sociedad de las relaciones entre los humanos y la naturaleza y para la mejora de las prácticas de la conservación y sus resultados. Existen cuatro barreras - ideológicas, institucionales, de conocimiento y de capacidad - para la integración significativa de las ciencias sociales dentro de la conservación. Proporcionamos una guía práctica sobre cómo sobreponerse a estas barreras para incorporar la perspectiva de las ciencias sociales a la ciencia, las prácticas y las políticas de conservación. En general, recomendamos promover el conocimiento sobre el alcance y las contribuciones de las ciencias sociales para la conservación, incluir a los científicos sociales desde el origen de los proyectos de investigación interdisciplinaria, incorporar la investigación de las ciencias sociales y las percepciones durante todas las fases de la planificación y la implementación de la conservación, construir la capacidad de las ciencias sociales en todas las escalas de las organizaciones y agencias de conservación y promover el compromiso con las ciencias sociales en y a través de organizaciones de conservación con influencia política. Los científicos sociales de la conservación, también, necesitan estar dispuestos a involucrarse con el conocimiento de las ciencias naturales y a comunicar percepciones y recomendaciones de manera clara. Le urgimos a la comunidad de la conservación que vaya más allá del compromiso superficial con las ciencias sociales de la conservación. Una ciencia de la conservación más incluyente y integradora - una que incluya a las ciencias sociales y naturales - permitirá una conservación más justa socialmente y más efectiva ecológicamente. Una mejor colaboración entre los científicos sociales, los científicos naturales, los practicantes y quienes elaboran las políticas facilitará una conservación más renovada y más sólida. Incorporar la perspectiva de las ciencias sociales de la conservación facilitará la absorción de la extensión completa de conocimiento y contribuciones de estos campos a la práctica y las políticas de la conservación.

Greenberg reviews \"Montgomery Clift: A Bio-Bibliography\" by Mary C. Kalfatovic.

Uphill shifts of species' distributions in response to historical warming are well documented, which leads to widespread expectations of continued uphill shifts under future warming. Conversely, downhill shifts are often considered anomalous and unrelated to climate change. By comparing the altitudinal distributions of 64 plant species between the 1930s and the present day within California, we show that climate changes have resulted in a significant downward shift in species' optimum elevations. This downhill shift is counter to what would be expected given 20th-century warming but is readily explained by species' niche tracking of regional changes in climatic water balance rather than temperature. Similar downhill shifts can be expected to occur where future climate change scenarios project increases in water availability that outpace evaporative demand.

Low levels of serum albumin may increase the risk of infections and mortality in critically ill patients. We tested the hypothesis that admission hypoalbuminemia predicted infectious complications and poor outcome in subjects with acute intracerebral hemorrhage (ICH). We analyzed a single center cohort of ICH patients collected between 1994 and 2015. Pneumonia, urinary tract infection and sepsis were retrospectively identified, according to validated criteria. Serum albumin was measured on admission and hypoalbuminemia was defined as total albumin ≤3.5 g/dL. The association between albumin levels, infections, and mortality at 90 days was tested with multivariable logistic regression analyses. A total of 2010 patients were included (median age 74 years, 54.5% males) of whom 444 (22.1%) had hypoalbuminemia on admission and 763 (38%) died within 90 days. The frequency of pneumonia, urinary tract infection, and sepsis was 19.9, 15.1, and 2.7%, respectively. Hypoalbuminemic patients had lower admission Glasgow coma scale, higher frequency of intraventricular hemorrhage and were more likely to have a history of chronic kidney or liver disease. After adjustment for potential confounders, hypoalbuminemia was an independent predictor of pneumonia [odds ratio (OR) 1.76, 95% confidence interval (CI) 1.34–2.33, p  < 0.001] and sepsis (OR 2.29, 95% CI 1.22–4.30, p  = 0.010). Low levels of albumin were also independently associated with higher mortality at 90 days (OR 1.78, 95% CI 1.30–2.44, p  < 0.001). In conclusion, early hypoalbuminemia is common and predicts poor outcome in ICH patients. Increased susceptibility to pneumonia and sepsis may be the pathophysiological mechanism underlying this association.

IntroductionAcute non-traumatic convexity subarachnoid haemorrhage (cSAH) is increasingly recognised in cerebral amyloid angiopathy (CAA). We investigated: (a) the overlap between acute cSAH and cortical superficial siderosis—a new CAA haemorrhagic imaging signature and (b) whether acute cSAH presents with particular clinical symptoms in patients with probable CAA without lobar intracerebral haemorrhage.MethodsMRI scans of 130 consecutive patients meeting modified Boston criteria for probable CAA were analysed for cortical superficial siderosis (focal, ≤3 sulci; disseminated, ≥4 sulci), and key small vessel disease markers. We compared clinical, imaging and cortical superficial siderosis topographical mapping data between subjects with versus without acute cSAH, using multivariable logistic regression.ResultsWe included 33 patients with probable CAA presenting with acute cSAH and 97 without cSAH at presentation. Patients with acute cSAH were more commonly presenting with transient focal neurological episodes (76% vs 34%; p<0.0001) compared with patients with CAA without cSAH. Patients with acute cSAH were also more often clinically presenting with transient focal neurological episodes compared with cortical superficial siderosis-positive, but cSAH-negative subjects with CAA (76% vs 30%; p<0.0001). Cortical superficial siderosis prevalence (but no other CAA severity markers) was higher among patients with cSAH versus those without, especially disseminated cortical superficial siderosis (49% vs 19%; p<0.0001). In multivariable logistic regression, cortical superficial siderosis burden (OR 5.53; 95% CI 2.82 to 10.8, p<0.0001) and transient focal neurological episodes (OR 11.7; 95% CI 2.70 to 50.6, p=0.001) were independently associated with acute cSAH.ConclusionsThis probable CAA cohort provides additional evidence for distinct disease phenotypes, determined by the presence of cSAH and cortical superficial siderosis.

Loss of cortical grey matter is a diagnostic marker of many neurodegenerative diseases, and is a key mediator of cognitive impairment. We postulated that cerebral amyloid angiopathy (CAA), characterised by cortical vascular amyloid deposits, is associated with cortical tissue loss independent of parenchymal Alzheimer's disease pathology. We tested this hypothesis in patients with hereditary cerebral haemorrhage with amyloidosis–Dutch type (HCHWA-D), a monogenetic disease with minimal or no concomitant Alzheimer's disease pathology, as well as in patients with sporadic CAA and healthy and Alzheimer's disease controls. In this observational case-control study, we included six groups of participants: patients diagnosed with HCHWA-D using genetic testing; healthy controls age-matched to the HCHWA-D group; patients with probable sporadic CAA without dementia; two independent cohorts of healthy controls age-matched to the CAA group; and patients with Alzheimer's disease age-matched to the CAA group. De-identified (but unmasked) demographic, clinical, radiological, and genetic data were collected at Massachusetts General Hospital (Boston, MA, USA), at Leiden University (Leiden, Netherlands), and at sites contributing to Alzheimer's Disease Neuroimaging Initiative (ADNI). The primary outcome measure was cortical thickness. The correlations between cortical thickness and structural lesions, and blood-oxygen-level-dependent time-to-peak (BOLD-TTP; a physiological measure of vascular dysfunction) were analysed to understand the potential mechanistic link between vascular amyloid and cortical thickness. The radiological variables of interest were quantified using previously validated computer-assisted tools, and all results were visually reviewed to ensure their accuracy. Between March 15, 2006, and Dec 1, 2014, we recruited 369 individuals (26 patients with HCHWA-D and 28 age-matched, healthy controls; 63 patients with sporadic CAA without dementia; two healthy control cohorts with 63 and 126 individuals; and 63 patients with Alzheimer's disease). The 26 patients with HCHWA-D had thinner cortices (2·31 mm [SD 0·18]) than the 28 healthy controls (mean difference −0·112 mm, 95% CI −0·190 to −0·034, p=0·006). The 63 patients with sporadic CAA without dementia had thinner cortices (2·17 mm [SD 0·11]) than the two healthy control cohorts (n=63, mean difference −0·14 mm, 95% CI −0·17 to −0·10, p<0·0001; and n=126, −0·10, −0·13 to −0·06, p<0·0001). All differences remained independent in multivariable analyses. The 63 patients with Alzheimer's disease displayed more severe atrophy than the patients with sporadic CAA (2·1 mm [SD 0·14], difference 0·07 mm, 95% CI 0·11 to 0·02, p=0·005). We found strong associations between cortical thickness and vascular dysfunction in the patients with HCHWA-D (ρ=–0·58, p=0·003) or sporadic CAA (r=–0·4, p=0·015), but not in controls. Vascular dysfunction was identified as a mediator of the effect of hereditary CAA on cortical atrophy, accounting for 63% of the total effect. The appearance of cortical thinning in patients with HCHWA-D indicates that vascular amyloid is an independent contributor to cortical atrophy. These results were reproduced in patients with the more common sporadic CAA. Our findings also suggest that CAA-related cortical atrophy is at least partly mediated by vascular dysfunction. Our results also support the view that small vessel diseases such as CAA can cause cortical atrophy even in the absence of Alzheimer's disease, a conclusion that can help radiologists, neurologists, and other clinicians who diagnose these common geriatric conditions. National Institutes of Health.