Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
519
result(s) for
"Guzmán, Mónica"
Sort by:
I never thought of it that way : how to have fearlessly curious conversations in dangerously divided times
Partisanship is up, trust is down, and our social media feeds make us sure we're right and everyone else is ignorant (or worse). But avoiding one another is hurting our relationships and our society. Journalist Mónica Guzmán is the loving liberal daughter of Mexican immigrants who voted--twice--for Donald Trump. When the country could no longer see straight across the political divide, Mónica set out to find what was blinding us and discovered the most eye-opening tool we're not using: our own built-in curiosity. In this timely, personal guide, Mónica, the chief storyteller for the national cross-partisan depolarization organization Braver Angels, takes you to the real front lines of a crisis that threatens to grind America to a halt--broken conversations among confounded people. She shows you how to overcome the fear and certainty that surround us to finally do what only seems impossible: understand and even learn from people in your life whose whole worldview is different from or even opposed to yours. Drawing from cross-partisan conversations she's had, organized, or witnessed everywhere from the echo chambers on social media to the wheat fields in Oregon to raw, unfiltered fights with her own family on election night, Mónica shows how you can put your natural sense of wonder to work for you immediately, finding the answers you need by talking with people--rather than about them--and asking the questions you want, curiously. Whether you're left, right, center, or not a fan of labels: If you're ready to fight back against the confusion, heartbreak, and madness of our dangerously divided times--in your own life, at least--Mónica's got the tools and fresh, surprising insights to prove that seeing where people are coming from isn't just possible. It's easier than you think--Publisher's description.
Book
Nationwide potential groundwater recharge trends in Bolivia: a remote sensing approach and a policy-ready decline indicator
Groundwater provides global water security, supplying over half of the world’s drinking water. In Bolivia, it is particularly important for mitigating drought impacts and sustaining municipal supply. Yet national planning still lacks a clear picture of how groundwater recharge is changing. This study maps potential groundwater recharge change for all 338 municipalities from 1983 to 2022 and presents a policy-oriented risk indicator. Monthly precipitation (P), evapotranspiration (ET), and runoff (R) were obtained from TerraClimate (≈4 km) and FLDAS (≈10 km). A water-balance model converted these variables to potential groundwater recharge. Mann–Kendall and Theil–Sen statistics quantified long-term trends, and Pettitt’s test located years of abrupt change. The Annual Reduction of Potential Groundwater Recharge (RAPReHS) was derived to classify each municipality into one of five risk levels based on long-term groundwater recharge trends. Negative trends are significant in 65% of municipalities, and 71% record at least one breakpoint, most often between 2012 and 2015. Santa Cruz shows the steepest mean decline (–1.9 mm yr−1), yet similar losses occur along the Chapare–Yungas corridor of La Paz and Cochabamba, the southern lowlands of Beni, and the Chaco of Tarija. By contrast, Pando and parts of northern Beni retain near-neutral or slightly positive slopes, highlighting strong hydro-climatic heterogeneity. Spatial comparison between RAPReHS results and, deforestation and fire statistics reveals strong alignment. Municipalities in the ‘high’ and ‘severe’ classes spatially overlap with the main zones of primary forest loss recorded in Bolivia between 2000 and 2022. The RAPReHS framework, therefore, provides a reproducible, policy-ready lens through which to track groundwater as land-use pressures and climate variability intensify.
Journal Article
Impacts of Wildfires on Groundwater Recharge: A Comprehensive Analysis of Processes, Methodological Challenges, and Research Opportunities
Increasing wildfire activity has led to complex ecosystem consequences, with direct effects on the subsystems that affect the presence and movement of water. Although studies have investigated the cascading effects of wildfires on the water balance, our understanding of broad-scale groundwater modifications post fire remains unclear. This review aims to elucidate fire-induced shifts in the water balance, their causal factors, and their potential effects on groundwater recharge. By scrutinizing prior research examples that modeled post-fire recharge scenarios, the review highlights persistent knowledge gaps. The challenge of quantifying and integrating fire-induced alterations in precipitation, wind, and land temperature patterns into recharge projection models is specifically addressed. Despite these gaps, post-fire values of hydrologically meaningful parameters such as leaf area index (LAI), curve number (CN), and near-surface saturated hydraulic conductivity (KST) have been identified. Simulating post-fire recharge via the extrapolation of these values requires the consideration of site-specific conditions, vegetation recovery, and ash removal. It frequently results in a reduced interception and increased surface runoff, while evapotranspiration remains dependent on site-specific factors and often dictates groundwater recharge estimates. Although post-fire recharge simulations are inherently complex and imprecise, their growing application can guide land-use alterations and support policy implementation that considers fire-induced water availability changes.
Journal Article
Measuring adult romantic attachment: psychometric properties of the brief Spanish version of the experiences in close relationships
The
Experiences in Close Relationships
(Brennan et al, Attachment theory and close relationships, 1998) questionnaire is one of the most widely used measures of adult romantic attachment. Despite the advantages of the ECR, the length of this measure may discourage its use in clinical and research contexts. Consequently, the goal of this study was to develop a brief Spanish version of the ECR questionnaire and to examine its psychometric properties when administered to six different Spanish-speaking samples from Chile. Confirmatory factor analyses replicated the two-dimensional structure of the ECR and its invariance across gender. Results also supported the reliability and concurrent validity of our brief Spanish version of the ECR (i.e., Spanish ECR-12), by its association with measures of emotion regulation, dyadic empathy, psychological distress and well-being, and relationship satisfaction. The Spanish ECR-12 can be used by researchers and clinical professionals as an abridged measure of adult attachment.
Journal Article
Why Do You Feel That Way? Elaboration Questions and Feeling Heard in Political Talk
Across two studies, the current work sought to understand the impact of elaboration questions in political discussion on perceptions of feeling heard and future discussion intentions. Participants were presented with a recorded video of a political conversation where we manipulated the presence and absence of elaboration questions in political conversations surrounding homelessness (Study 1) and abortion (Study 2). Results indicate the presence of elaboration questions increased perceptions of being heard and intentions to engage in discussion in the future. We also found significant indirect results where the relationship between elaboration questions and intentions to engage in future discussions was mediated by feeling heard. These findings were never moderated by whether participants agreed with the political stance taken in the conversation.
Journal Article
Modulation of Zinc Transporter Expressions by Additional Zinc in C2C12 Cells Cultured in a High Glucose Environment and in the Presence of Insulin or Interleukin-6
Zn status has been related to various chronic diseases presenting oxidative stress and inflammation, such as type 2 diabetes. Zn supplementation has been suggested to be a potential coadjuvant in the management of this condition. Zn transporters constitute a key component in the maintenance of Zn homeostasis. Our aim was to evaluate the modulatory effect of additional Zn (10 or 100 µM; as a ZnSO
4
*7H
2
0) on the mRNA relative expression of selected Zn transporters (ZnT1, ZnT5, ZnT7, ZIP6, ZIP7, ZIP10, ZIP14), in myoblast (C2C12) cells cultured in normal (10 mM) and high glucose (30 mM), and in the absence or presence of insulin (1 nM), and interleukin-6 (IL-6; 5 nM) for 24 h. The main findings of our study were that in high glucose conditions in absence of insulin or IL-6, additional Zn increased ZnT1 and ZIP6, and decreased ZnT5 and ZIP7 expressions. However, this situation is modified by insulin, where incremental Zn induced increased expressions of ZnT1, ZnT5, and all the ZIP transporters studied. In high glucose conditions and in the presence of IL-6, additional Zn caused increased expressions of ZnT7, ZIP7, and ZIP14, compared with results in the absence of IL-6. This study provides preliminary evidence for the differential expression of selected Zn transporters in C2C12 cells subjected to high glucose and incremental Zn, suggesting that important changes in intracellular Zn distribution take place in response to inflammatory and high-insulin environments. Further study is necessary to understand the implications of these findings.
Journal Article
Zinc Modulates the Response to Apoptosis in an In Vitro Model with High Glucose and Inflammatory Stimuli in C2C12 Cells
Apoptosis is programmed cell death and its alteration is related to cancer, neurologic, autoimmune, and chronic diseases. A number of factors can affect this process. The aim of this paper is to study the effect of supplemental zinc on apoptosis-related genes in C2C12 myoblast cells after being challenged with a series of stimuli, such as high glucose, insulin, and an inflammatory agent. C2C12 myoblast cells were cultured for 24 h with zinc (Zn) (ZnSO4) 10 or 100 μM and/or glucose 10 or 30 mM. In addition to these stimuli, the cells were challenged with insulin 1 nM or interleukin-6 (IL-6) 5 nM. The mRNA expression of proapoptotic genes caspase 3 and Fas, the antiapoptotic genes, Xiap and Bcl-xL and the ratio of pro-/antiapoptotic genes Bax/Bcl-2, were determined by qRT-PCR. The expression of caspase-3 gene was significantly increased in the presence of the combination high Zn/high glucose with and without the presence of insulin and IL6 in the culture medium Fas expression instead, showed uneven responses. The expression of Bcl-xL and Xiap was increased in most conditions by having high Zn in the medium regardless of the presence of insulin or IL6. Bax/Bcl2 ratio was decreased in the presence of high Zn. Zn was able to stimulate the expression of antiapoptotic genes. This effect was specially noted in high-glucose conditions with and without the presence of insulin. This effect is partially overridden by the presence of an inflammatory agent such as IL-6.
Journal Article
Damage Control Surgery may be a Safe Option for Severe Non-Trauma Peritonitis Management: Proposal of a New Decision-Making Algorithm
Background
Damage control surgery (DCS) has emerged as a new option in the management of non-traumatic peritonitis patients to increase survival in critically ill patients. The purpose of this study was to compare DCS with conventional strategy (anastomosis/ostomies in the index laparotomy) for severe non-traumatic peritonitis regarding postoperative complications, ostomy rate, and mortality and to propose a useful algorithm in the clinical practice.
Methods
Patients who underwent an urgent laparotomy for non-trauma peritonitis at a single level I trauma center in Colombia between January 2003 and December 2018, were retrospectively included. We compared patients who had DCS management versus definitive initial surgical management (DISM) group. We evaluated clinical outcomes and morbidities among groups.
Results
290 patients were included; 81 patients were treated with DCS and 209 patients underwent DISM. Patients treated with DCS had a worse critical status before surgery with higher SOFA score [median, DCS group: 5 (IQR: 3–8) vs. DISM group: 3 (IQR: 1–6),
p
< 0.001]. The length of hospital stay and overall mortality rate of DCS group were not significant statistical differences with DISM group. Complications rate related to primary anastomosis or primary ostomy was similar. There is not difference in ostomy rate among groups. At multivariate analysis, SOFA > 6 points and APACHE-II > 20 points correlated with a higher probability of DCS.
Conclusion
DCS in severe non-trauma peritonitis patients is feasible and safe as surgical strategy management without increasing mortality, length hospital of stay, or complications. DCS principles might be applied in the non-trauma scenarios without increase the stoma rate.
Journal Article
Multi-Criteria Prioritization of Watersheds for Post-Fire Restoration Using GIS Tools and Google Earth Engine: A Case Study from the Department of Santa Cruz, Bolivia
The Santa Cruz department in Bolivia is characterized by a wide range of ecosystems and by its richness in water resources. In recent years, extended drought caused by climate change has led to extensive fire events. Combined with deforestation, this is resulting in the degradation of the region’s ecosystems and water resources. To address restoration needs from both a land- and water-management perspective, this study proposes to prioritize restoration areas by applying a multi-criteria analysis (MCA) based on two main principles: (1) using the watershed as the main study unit and (2) involving stakeholders in the definition of priority watersheds. Local stakeholders selected criteria representing water resources, biophysical characteristics, land management, productive areas, and fire disaster threats, and reclassified the spatial information based on perceived importance. Different prioritization scenarios were developed and compared in a Google Earth Engine (GEE) application. Priority restoration areas largely depend on the weighting scheme. Focusing solely on past fires leads to prioritizing the south-east basins, while the conservation of the western watersheds becomes more important when increasing the weight of the water resources criteria. This study represents the first step in developing a participatory MCA tool at the watershed scale in Santa Cruz. Highlighting the impact of different prioritization criteria can support collective decision-making around land and watershed restoration.
Journal Article
Fontan surgery failure: risk factors and experience in a Colombian reference centre
The Fontan procedure is considered one of the most remarkable achievements in paediatric cardiology and cardiac surgery. Its final anatomical objective is a venous return through the superior and inferior vena cava. The complications inherent to this procedure and subsequent failure are its limitations.
To describe the clinical and haemodynamic characteristics of patients with Fontan failure and define the risk factors associated with it, with its short- and long-term outcomes during a 21-year observation period.
This is a retrospective follow-up study in which 15 patients diagnosed with Fontan failure in the single-ventricle programme of a high-complexity hospital in Medellín, Colombia, between 2001 and 2022 were included.
One hundred and eight patients were identified in whom the Fontan procedure was performed, and 17 met the failure criteria. 82.4% were men, with a median age of 4.3 years. Ebstein's anomaly was the most common diagnosis, 29.4%. All patients underwent Fontan with an extracardiac tube following the procedure. According to the type of failure, 58.8% of patients presented protein-losing enteropathy and 17.6% plastic bronchitis. During follow-up, 5.9% of patients died.
Fontan surgery in our centre is an option for patients with univentricular physiology. The correct selection of the patient is essential to mitigate failure risks.
Journal Article