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"Hall, Jon"
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Cicero's use of judicial theater
\" In Cicero's Use of Judicial Theater, Jon Hall examines Cicero's use of showmanship in the Roman law-courts, looking in particular at the nonverbal devices that he employs during his speeches as he attempts to manipulate opinion. Cicero's speeches in the law-courts often incorporate theatrical devices including the use of family relatives as props during emotional appeals, exploitation of tears and supplication, and the wearing of specially dirtied attire by defendants during a trial, all of which contrast strikingly with the practices of the modem advocate. Hall investigates how Cicero successfully deployed these techniques and why they played such a prominent part in the Roman courts. These \"judicial theatrics\" are rarely discussed by the ancient rhetorical handbooks, and Cicero's Judicial Theater argues that their successful use by Roman orators derives largely from the inherent theatricality of aristocratic life in ancient Rome--most of the devices deployed in the courts appear elsewhere in the social and political activities of the elite. While Cicero's Judicial Theater will be of interest primarily to professional scholars and students studying the speeches of Cicero, its wider analyses, both of Roman cultural customs and the idiosyncratic practices of the law-courts, will prove relevant also to social historians, as well as historians of legal procedure\"-- Provided by publisher.
Book
Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study
There is growing evidence supporting clinically important associations between age at neutering in bitches and subsequent urinary incontinence (UI), although much of this evidence to date is considered weak. Target trial emulation is an innovative approach in causal inference that has gained substantial attention in recent years, aiming to simulate a hypothetical randomised controlled trial by leveraging observational data. Using anonymised veterinary clinical data from the VetCompass Programme, this study applied the target trial emulation framework to determine whether later-age neutering (≥ 7 to ≤ 18 months) causes decreased odds of early-onset UI (diagnosed < 8.5 years) compared to early-age neutering (3 to < 7 months). The study included bitches in the VetCompass database born from January 1, 2010, to December 31, 2012, and neutered between 3 and 18 months old. Bitches were retrospectively confirmed from the electronic health records as neutered early or later. The primary outcome was a diagnosis of early-onset UI. Informed from a directed acyclic graph, data on the following covariates were extracted: breed, insurance status, co-morbidities and veterinary group. Inverse probability of treatment weighting was used to adjust for confounding, with inverse probability of censoring weighting accounting for censored bitches. The emulated trial included 612 early-age neutered bitches and 888 later-age neutered bitches. A pooled logistic regression outcome model identified bitches neutered later at 0.80 times the odds (95% CI 0.54 to 0.97) of early-onset UI compared with bitches neutered early. The findings show that later-age neutering causes reduced odds of early-onset UI diagnosis compared with early-age neutering. Decision-making on the age of neutering should be carefully considered, with preference given to delaying neutering until after 7 months of age unless other major reasons justify earlier surgery. The study is one of the first to demonstrate successful application of the target trial framework to veterinary observational data.
Journal Article
A companion to Roman rhetoric
A Companion to Roman Rhetoric introduces the reader to the wide-ranging importance of rhetoric in Roman culture. A guide to Roman rhetoric from its origins to the Renaissance and beyond Comprises 32 original essays by leading international scholars Explores major figures Cicero and Quintilian in-depth Covers a broad range of topics such as rhetoric and politics, gender, status, self-identity, education, and literature Provides suggestions for further reading at the end of each chapter Includes a glossary of technical terms and an index of proper names and rhetorical concepts
eBook
Star Wars : complete locations
The ultimate reference book for the planets, cities, and battles of the Star wars galaxy! The cross-section artworks offer incredible levels of detail that take you far beyond what is seen on-screen-- even beyond freeze-frame!
Book
Using complexity and volatility characteristics to guide hybrid project management
PurposeThe paper aims to provide methodological support for hybrid project management, in which the discipline of predictive methodologies combines with the flexibility of adaptive ones. Specifically, the paper explores the extent complexity and volatility dimensions of organisational problems inform choices of PM methodologies both theoretically and in current practice, as a first step towards better methodological support for hybridisation.Design/methodology/approachThe paper takes a mixed method approach, including both secondary research and primary research with practitioners. Primary research consists of a small scale survey (n = 31) followed by semi-structured interviews, with findings triangulated against secondary evidence.FindingsThe paper provides empirical insights on how complexity and volatility of organisational problems can inform hybrid project management practices. Specifically, it suggests a mapping between volatility and complexity dimensions and predictive and adaptive risk controls as a first step towards the systematisation of hybrid combinations in projects.Research limitations/implicationsDue to the small participant sample, the research results may lack generalisability.Practical implicationsThe paper includes implications for the development of methodological support for setting up hybrid projects in practice.Originality/valueThe paper addresses a gap acknowledged both in the literature and by practitioners.
Journal Article
Comparing the accuracy of freehand, fluoroscopically guided and aiming device-assisted drilling in veterinary orthopaedic surgery
BackgroundDrilling accuracy is essential in the correct positioning of implants and avoidance of iatrogenic damage to surrounding tissues. The use of augmented drilling methods has been documented as an approach to improving the accuracy of drilling. The aim of this study was to compare the accuracy of two augmented drilling methods (fluoroscopically guided and aiming device) to freehand (FH) drilling.MethodsThree experienced specialist surgeons and three veterinary surgeons without primary orthopaedic experience drilled into synthetic bone towards a target using the three different methods at three different angles (0°, 10° and 20°). The duration of drilling was recorded, and the accuracy of drilling was measured using photographs before and after drilling.ResultsThe two augmented methods were more accurate than FH drilling in synthetic bone, with the aiming device producing the greatest accuracy. Increased angulation of drilling decreased the drilling accuracy. Surgeon experience did not impact on drilling accuracy. Surgeon inexperience and augmented drilling methods both increased the time taken to drill.ConclusionThe use of augmented drilling methods improved the accuracy of drilling, and surgeons should consider their use when drilling in anatomical regions where the margin of error is small.
Journal Article
Sequential drilling and drill angulation reduce the accuracy of drill hole start location in a synthetic bone model
The accuracy of drill hole location is critical for implant placement in orthopaedic surgery. Increasing drill bit size sequentially has been suggested as a method for improving the accuracy of drill hole start location. The aim of this study was to determine whether sequential drilling or drill angulation would alter accuracy of drill hole start location. Three specialist veterinary surgeons drilled holes in synthetic bone models either directly, or with sequentially increasing drill bit sizes. Drilling was performed at 0o, 10o and 20o to perpendicular to the bone models. Three synthetic bone models were used to mimic canine cancellous and cortical bones. Sequential drilling resulted in greater inaccuracy in drill hole location when assessing all drilling angles together. There was no influence of surgeon or synthetic bone density on drilling accuracy. The combination of drill angulation and sequential drilling increased inaccuracy in drill hole start location. We conclude that sequential drilling decreased accuracy of drill hole location in the synthetic bone model when drilling was angled. Inaccuracy associated with the drill hole start location should be taken into account when performing surgery, although the magnitude of inaccuracy is low when compared with other sources of error such as angulation.
Journal Article
Primary retropharyngeal leiomyosarcoma in a young cat
Case summary An Oriental Shorthair cat, aged 1 year and 6 months, developed progressive stridor and a palpable right ventral cervical mass. Fine-needle aspiration of the mass was inconclusive, while thoracic radiography and CT showed no evidence of metastasis. There was initial improvement in stridor with oral doxycycline and prednisolone treatment, but it recurred 4 weeks later and excisional biopsy was performed. Histopathology with immunohistochemistry diagnosed leiomyosarcoma with incomplete surgical margins. Adjunctive radiation therapy was declined. Repeated physical examination and CT 7 months postoperatively documented no evidence of mass recurrence. Relevance and novel information This is the first reported case of retropharyngeal leiomyosarcoma in a young cat with no evidence of local reoccurrence 7 months following an excisional biopsy.
Journal Article
Integrating In Vitro Biopharmaceutics into Physiologically Based Biopharmaceutic Model (PBBM) to Predict Food Effect of BCS IV Zwitterionic Drug (GSK3640254)
A strategy followed to integrate in vitro solubility and permeability data into a PBBM model to predict the food effect of a BCS IV zwitterionic drug (GSK3640254) observed in clinical studies is described. The PBBM model was developed, qualified and verified using clinical data of an immediate release (IR)-tablet (10–320 mg) obtained in healthy volunteers under fasted and fed conditions. The solubility of GSK3640254 was a function of its ionization state, the media composition and pH, whereas its permeability determined using MDCK cell lines was enhanced by the presence of mixed micelles. In vitro data alongside PBBM modelling suggested that the positive food effect observed in the clinical studies was attributed to micelle-mediated enhanced solubility and permeability. The biorelevant media containing oleic acid and cholesterol in fasted and fed levels enabled the model to appropriately capture the magnitude of the food effect. Thus, by using Simcyp® v20 software, the PBBM model accurately predicted the results of the food effect and predicted data were within a two-fold error with 70% being within 1.25-fold. The developed model strategy can be effectively adopted to increase the confidence of using PBBM models to predict the food effect of BCS class IV drugs.
Journal Article