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As one of the most popular financial market instruments, the stock has formed one of the most massive and complex financial markets in the world. It could handle millions of transactions within a short period of time and highly unpredictable. In this study, we aim to implement a famous Deep Learning method, namely the long short-term memory (LSTM) networks, for the stock price prediction. We limit the stocks to those that are included in the LQ45 financial sectors indices, i.e., BBCA, BBNI, BBRI, BBTN, BMRI, and BTPS. Rather than using too deep network architecture, we propose using a simple three-layer LSTM network architecture to predict the stocks’ closing prices. We found that the prediction results fall in the reasonable forecasting category. Moreover, it is worth noting that two of the considered stocks, namely, BBCA and BMRI, have the lowest MAPE values at 19.1020 and 18.6135, which fall in the good forecasting results. Hence, the proposed LSTM model is most recommended to be used on those two stocks.

As a new type of currency introduced in the new millennium, cryptocurrency has established its ecosystems and attracts many people to use and invest in it. However, cryptocurrencies are highly dynamic and volatile, making it challenging to predict their future values. In this research, we use a multivariate prediction approach and three different recurrent neural networks (RNNs), namely the long short-term memory (LSTM), the bidirectional LSTM (Bi-LSTM), and the gated recurrent unit (GRU). We also propose simple three layers deep networks architecture for the regression task in this study. From the experimental results on five major cryptocurrencies, i.e., Bitcoin (BTC), Ethereum (ETH), Cardano (ADA), Tether (USDT), and Binance Coin (BNB), we find that both Bi-LSTM and GRU have similar performance results in terms of accuracy. However, in terms of the execution time, both LSTM and GRU have similar results, where GRU is slightly better and has lower variation results on average.

Tuberculosis (TB) was the leading infectious cause of mortality globally prior to COVID-19 and chest radiography has an important role in the detection, and subsequent diagnosis, of patients with this disease. The conventional experts reading has substantial within- and between-observer variability, indicating poor reliability of human readers. Substantial efforts have been made in utilizing various artificial intelligence-based algorithms to address the limitations of human reading of chest radiographs for diagnosing TB. This systematic literature review (SLR) aims to assess the performance of machine learning (ML) and deep learning (DL) in the detection of TB using chest radiography (chest x-ray [CXR]). In conducting and reporting the SLR, we followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. A total of 309 records were identified from Scopus, PubMed, and IEEE (Institute of Electrical and Electronics Engineers) databases. We independently screened, reviewed, and assessed all available records and included 47 studies that met the inclusion criteria in this SLR. We also performed the risk of bias assessment using Quality Assessment of Diagnostic Accuracy Studies version 2 (QUADAS-2) and meta-analysis of 10 included studies that provided confusion matrix results. Various CXR data sets have been used in the included studies, with 2 of the most popular ones being Montgomery County (n=29) and Shenzhen (n=36) data sets. DL (n=34) was more commonly used than ML (n=7) in the included studies. Most studies used human radiologist's report as the reference standard. Support vector machine (n=5), k-nearest neighbors (n=3), and random forest (n=2) were the most popular ML approaches. Meanwhile, convolutional neural networks were the most commonly used DL techniques, with the 4 most popular applications being ResNet-50 (n=11), VGG-16 (n=8), VGG-19 (n=7), and AlexNet (n=6). Four performance metrics were popularly used, namely, accuracy (n=35), area under the curve (AUC; n=34), sensitivity (n=27), and specificity (n=23). In terms of the performance results, ML showed higher accuracy (mean ~93.71%) and sensitivity (mean ~92.55%), while on average DL models achieved better AUC (mean ~92.12%) and specificity (mean ~91.54%). Based on data from 10 studies that provided confusion matrix results, we estimated the pooled sensitivity and specificity of ML and DL methods to be 0.9857 (95% CI 0.9477-1.00) and 0.9805 (95% CI 0.9255-1.00), respectively. From the risk of bias assessment, 17 studies were regarded as having unclear risks for the reference standard aspect and 6 studies were regarded as having unclear risks for the flow and timing aspect. Only 2 included studies had built applications based on the proposed solutions. Findings from this SLR confirm the high potential of both ML and DL for TB detection using CXR. Future studies need to pay a close attention on 2 aspects of risk of bias, namely, the reference standard and the flow and timing aspects. PROSPERO CRD42021277155; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=277155.

Medical Informatics (MI) is an emerging multidisciplinary study in academic fields. Also known as ‘Health Informatics,’ this study combines three different well-known fields; Information Systems (IS), Computer Science (CS), and Health Science (HS). MI is crucial because it could help in bridging the gap that is commonly found in conventional Healthcare services with the usage of Information Technology (IT). However, despite its vital role, the development of MI in Indonesia is still not satisfactory. Therefore, in this paper, the importance of MI as an academic discipline will be briefly discussed, followed by the description of MI development in Indonesia, and some suggestions for its future development.

Tuberculosis (TB) remains a significant health concern, contributing to the highest mortality among infectious diseases worldwide. However, none of the various TB diagnostic tools introduced is deemed sufficient on its own for the diagnostic pathway, so various artificial intelligence (AI)-based methods have been developed to address this issue. We aimed to provide a comprehensive evaluation of AI-based algorithms for TB detection across various data modalities. Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) 2020 guidelines, we conducted a systematic review to synthesize current knowledge on this topic. Our search across 3 major databases (Scopus, PubMed, Association for Computing Machinery [ACM] Digital Library) yielded 1146 records, of which we included 152 (13.3%) studies in our analysis. QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies version 2) was performed for the risk-of-bias assessment of all included studies. Radiographic biomarkers (n=129, 84.9%) and deep learning (DL; n=122, 80.3%) approaches were predominantly used, with convolutional neural networks (CNNs) using Visual Geometry Group (VGG)-16 (n=37, 24.3%), ResNet-50 (n=33, 21.7%), and DenseNet-121 (n=19, 12.5%) architectures being the most common DL approach. The majority of studies focused on model development (n=143, 94.1%) and used a single modality approach (n=141, 92.8%). AI methods demonstrated good performance in all studies: mean accuracy=91.93% (SD 8.10%, 95% CI 90.52%-93.33%; median 93.59%, IQR 88.33%-98.32%), mean area under the curve (AUC)=93.48% (SD 7.51%, 95% CI 91.90%-95.06%; median 95.28%, IQR 91%-99%), mean sensitivity=92.77% (SD 7.48%, 95% CI 91.38%-94.15%; median 94.05% IQR 89%-98.87%), and mean specificity=92.39% (SD 9.4%, 95% CI 90.30%-94.49%; median 95.38%, IQR 89.42%-99.19%). AI performance across different biomarker types showed mean accuracies of 92.45% (SD 7.83%), 89.03% (SD 8.49%), and 84.21% (SD 0%); mean AUCs of 94.47% (SD 7.32%), 88.45% (SD 8.33%), and 88.61% (SD 5.9%); mean sensitivities of 93.8% (SD 6.27%), 88.41% (SD 10.24%), and 93% (SD 0%); and mean specificities of 94.2% (SD 6.63%), 85.89% (SD 14.66%), and 95% (SD 0%) for radiographic, molecular/biochemical, and physiological types, respectively. AI performance across various reference standards showed mean accuracies of 91.44% (SD 7.3%), 93.16% (SD 6.44%), and 88.98% (SD 9.77%); mean AUCs of 90.95% (SD 7.58%), 94.89% (SD 5.18%), and 92.61% (SD 6.01%); mean sensitivities of 91.76% (SD 7.02%), 93.73% (SD 6.67%), and 91.34% (SD 7.71%); and mean specificities of 86.56% (SD 12.8%), 93.69% (SD 8.45%), and 92.7% (SD 6.54%) for bacteriological, human reader, and combined reference standards, respectively. The transfer learning (TL) approach showed increasing popularity (n=89, 58.6%). Notably, only 1 (0.7%) study conducted domain-shift analysis for TB detection. Findings from this review underscore the considerable promise of AI-based methods in the realm of TB detection. Future research endeavors should prioritize conducting domain-shift analyses to better simulate real-world scenarios in TB detection. PROSPERO CRD42023453611; https://www.crd.york.ac.uk/PROSPERO/view/CRD42023453611.

Despite being a curable disease, Tuberculosis has become the leading cause of death of infectious disease prior to COVID-19. It has asymptomatic infections that are hard to detect for weeks or years. Although there have been many studies on Tuberculosis disease detection and prevention, very few of them discussing the creation of an expert system based on API. Hence, in this study we propose an Expert API that implements Forward Chaining and Certainty Factor algorithms for the task of Tuberculosis early detection. The evaluation of the proposed system was carried out using several testing methods and in-depth interview with medical experts. We got a satisfactory result for this study.

Purpose Non-invasive, beat-to-beat variations in physiological indices provide an opportunity for more accessible assessment of autonomic dysfunction. The potential association between the changes in these parameters and arterial stiffness in hypertension remains poorly understood. This systematic review aims to investigate the association between non-invasive indicators of autonomic function based on beat-to-beat cardiovascular signals with arterial stiffness in individuals with hypertension. Methods Four electronic databases were searched from inception to June 2022. Studies that investigated non-invasive parameters of arterial stiffness and autonomic function using beat-to-beat cardiovascular signals over a period of > 5min were included. Study quality was assessed using the STROBE criteria. Two authors screened the titles, abstracts, and full texts independently. Results Nineteen studies met the inclusion criteria. A comprehensive overview of experimental design for assessing autonomic function in terms of baroreflex sensitivity and beat-to-beat cardiovascular variabilities, as well as arterial stiffness, was presented. Alterations in non-invasive indicators of autonomic function, which included baroreflex sensitivity, beat-to-beat cardiovascular variabilities and hemodynamic changes in response to autonomic challenges, as well as arterial stiffness, were identified in individuals with hypertension. A mixed result was found in terms of the association between non-invasive quantitative autonomic indices and arterial stiffness in hypertensive individuals. Nine out of 12 studies which quantified baroreflex sensitivity revealed a significant association with arterial stiffness parameters. Three studies estimated beat-to-beat heart rate variability and only one study reported a significant relationship with arterial stiffness indices. Three out of five studies which studied beat-to-beat blood pressure variability showed a significant association with arterial structural changes. One study revealed that hemodynamic changes in response to autonomic challenges were significantly correlated with arterial stiffness parameters. Conclusions The current review demonstrated alteration in autonomic function, which encompasses both the sympathetic and parasympathetic modulation of sinus node function and vasomotor tone (derived from beat-to-beat cardiovascular signals) in hypertension, and a significant association between some of these parameters with arterial stiffness. By employing non-invasive measurements to monitor changes in autonomic function and arterial remodeling in individuals with hypertension, we would be able to enhance our ability to identify individuals at high risk of cardiovascular disease. Understanding the intricate relationships among these cardiovascular variability measures and arterial stiffness could contribute toward better individualized treatment for hypertension in the future. Systematic review registration : PROSPERO ID: CRD42022336703. Date of registration: 12/06/2022.

Time series are one of the most common data types encountered by data scientists and, in the context of today's exponentially increasing data, learning how to best model them to derive meaningful insights is an important skill in the Big Data and Data Science toolbox. As a result, many researchers have dedicated their efforts to developing time series analysis methods to predict future values based on previously observed values. One of the well-known methods is the Holt-Winters' seasonal method, which is commonly used to capture the seasonality effect in time series data. In this study, the authors aim to build upon the Holt-Winters' additive method by introducing new formulas for finding the initial values. Obtaining more accurate estimations of the initial values could result in a better forecasting result. The authors use the basic principle found in the weighted moving average method to assign more weight to the most recent data and combine it with the original initial conditions found in the Holt-Winters' additive method. Based on the experiment performed, the authors conclude that the new formulas for finding the initial values in the Holt-Winters' additive method could give a better forecasting when compared to the traditional Holt-Winters' additive method and the weighted moving average method in terms of the accuracy level.

Presently, the Forex market has become the world’s largest financial market with more than US$5 trillion daily volume. Therefore, it attracts many researchers to learn its traded currency pairs characteristics and predict their future values. Here, we propose simple three layers Bidirectional long short-term memory (Bi-LSTM) networks for Forex forecasting with four different merge modes. Moreover, the proposed model is also compared to the conventional long short-term memory (LSTM) networks with the same architecture. Five major Forex currency pairs, namely AUD/USD, EUR/USD, GBP/USD, USD/CHF, and USD/JPY, with more than ten years of historical records are considered in this study. It is revealed from the experimental results that among four available merge modes, the concatenation mode as the default merge mode in Bi-LSTM networks is actually the less preferred mode for Forex forecasting (Root mean square error 0.30685517, mean absolute error 0.27442235, mean absolute percentage error 0.827108%). Moreover, Bi-LSTM average mode gets the highest R2 score that could achieve 89.579%. Therefore, the proposed three layers Bi-LSTM networks could provide a baseline result for developing a good trading strategy in Forex forecasting.

In driving, the most important thing to be considered is safety. The incident problem can happen anytime and anywhere without anyone knowing it before, especially in Cikarang where the level of incident is quite high. It is very important for the public community to act and respond quickly at the time on and around the occurring incident. Nolong.in application is an exact solution because it can send real time notifications to its users. This response is meant to assist individuals who have been using Nolong.in to help other users who need urgent help when the time of incident in order to prevent unwanted situations. In this research, push notification method has been implemented by using Firebase Cloud Messaging (FCM). The result of the research is the notification click ratio is 90.91% and the click time is 1 minute and 27 seconds. Based on the questionnaires’ results given to the community conclude that Nolong.in application is very beneficial for Gojek Cikarang community's safety.