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Diet and dietary components have profound effects on the composition of the gut microbiota and are among the most important contributors to the alteration in bacterial flora. This review examines the effects the “Western”, “plant-based”, “high-fat”, “medical ketogenic”, and “Mediterranean” diets have on the composition of the gut microbiota in both mice and human subjects. We show that specific dietary components that are commonly found in the “plant-based” and “Mediterranean” diet play a role in shifting the microbial composition. This review further evaluates the bacterial metabolites that are associated with diet, and their role in systemic inflammation and metabolic endotoxemia. Furthermore, the associations between diet/dietary components and altering bacterial composition, may lead to potential therapeutic targets for type II diabetes, obesity, and inflammatory diseases.

This study investigates the role of Douyin, internationally known as TikTok, in shaping the presentation and perception of minzu (ethnicity) among ethnic minority wanghongs (internet celebrities) in China. It examines how Douyin’s techno-social environment, particularly the “surveillance technicity” embedded within its algorithms, interacts with the content production and engagement practices of ethnic minority creators, thereby co-constructing their self-perception and expression of ethnic identity. The paper emphasizes how wanghongs navigate both technology and identity, strategically crafting and materializing their minzu narratives within the constraints and opportunities of this digital platform. It highlights the complex interplay between Douyin’s algorithmic mechanisms and the emergent ethnic narratives of wanghongs, illustrating how Douyin is instrumental in the visibility, and renegotiation of ethnic identities among ethnic minority wanghongs. This analysis provides critical insights into the multifaceted impact of Douyin’s algorithms on the cultivation and transformation of ethnic identities within China’s digital spaces.

Most scholars have argued that student engagement positively predicts academic achievement, but some have challenged this view. We sought to resolve this debate by offering conclusive evidence through a meta-analysis of 69 independent studies (196,473 participants). The results revealed that (a) there was a moderately strong and positive correlation between overall student engagement and academic achievement, and an analysis of the domains of behavioral, emotional, and cognitive engagement showed that almost all had a positive correlation with students' academic achievement; and (b) a moderator analysis revealed that the relationship between student engagement and academic achievement was influenced by the method of reporting engagement, cultural value, and gender. Furthermore, the relationships of behavioral, emotional, and cognitive engagement with academic achievement were influenced by reporting method for engagement, cultural value, or gender.

Ground-state charge transfer plays a vital role in improving the photocatalytic performance of D-A type covalent organic frameworks. However, limited studies have explored the modulation of photocatalytic performance in COFs-based photocatalysts through ground-state charge transfer. Here we show the formation of extremely intense ground-state charge transfer via a unique covalent bonding approach. We transform three-dimensional stacked COF-based S-scheme heterojunctions (FOOCOF-PDIU) into co-planar single-molecule junctions (FOOCOF-PDI). This co-planar single-molecule junction structure exhibits strong ground-state charge transfer compared to the traditional randomly stacked heterojunctions and individual COFs. Ground-state charge transfer induces charge redistribution and dipole moment formation, which enhances the built-in electric field intensity in single-molecule junctions. This enhanced built-in electric field promotes exciton dissociation and charge separation, resulting in improved photocatalytic efficiency. Therefore, a stable molecule-decorated COF with broad light absorption has been successfully obtained, whose hydrogen evolution rate can reach 265 mmol g −1  h −1 . This work opens an avenue for exploiting photocatalytic mechanisms in COFs based on ground-state charge transfer effects. Ground state charge transfer is important for improving the photocatalytic performance of donor-acceptor type covalent organic frameworks (COFs), but it has been underexplored. Here, the authors report a COF with enhanced charge transfer, achieving a hydrogen evolution rate of 265 mmol g −1  h −1 .

Background Out-of-hospital cardiac arrest (OHCA) is a leading cause of sudden cardiac death worldwide. Researchers have found significant pathophysiological differences between females and males and clinically significant sex differences related to medical services. However, conflicting results exist and there is no uniform agreement regarding sex differences in survival and prognosis after OHCA. Therefore, we investigated the relationship between the prognosis of OHCA and sex factors. Methods We comprehensively searched the PubMed, Embase, and Cochrane databases and obtained a total of 1042 articles, from which 33 studies were selected for inclusion. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a random-effects model. Results The meta-analysis included 1,268,664 patients. Compared with males, females were older (69.7 years vs. 65.4 years, p  < 0.05) and more frequently suffered OHCA without witnesses (58.39% vs 62.70%, p  < 0.05). Females were less likely to receive in-hospital interventions than males. There was no significant difference between females and males in the survival from OHCA to hospital admission (OR 0.99, 95% CI 0.89–1.1). However, females had lower chances for survival from hospital admission to discharge (OR 0.59, 95% CI 0.48–0.73), overall survival to hospital discharge (OR 0.73, 95% CI 0.62–0.86), and favorable neurological outcomes (OR 0.62, 95% CI 0.47–0.83) compared with males. Conclusions Our results indicate that the overall discharge survival rate of females is lower than that of males, and females face a poor prognosis of the nervous system. This is likely related to the pathophysiological characteristics of females, more conservative treatment measures compared with males, and different post-resuscitation care. However, these findings should be interpreted with caution due to the presence of several confounding factors.

Atrial fibrillation (AF) is a rapid supraventricular arrhythmia. However, the pathogenesis of atrial fibrillation remains controversial. We obtained transcriptome expression profiles GSE41177, GSE115574 and GSE79768 from GEO database. WGCNA was performed, DEGs were screened, PPI network was constructed using STRING database. CTD database was used to identify the reference score of hub genes associated with cardiovascular diseases. Prediction of miRNAs of hub genes was performed by TargetScan. DIANA‐miRPath v3.0 was applied to make functional annotation of miRNA. The animal model of atrial fibrillation was constructed, RT‐PCR was used to verify the expression of hub genes. Immunofluorescence assay for THBS2 and VCAN was made to identify molecular. Design of BP neural network was made to explore the prediction relationship of CXCR4 and TYROBP on AF. The merged datasets contained 104 up‐regulated and 34 down‐regulated genes. GO and KEGG enrichment analysis results of DEGs showed they were mainly enriched in ‘regulation of release of sequestered calcium ion into cytosol’, ‘actin cytoskeleton organization’ and ‘focal adhesion’. The hub genes were CXCR4, SNAI2, S100A4, IGFBP3, CSNK2A1, CHGB, VCAN, APOE, C1QC and TYROBP, which were up‐regulated expression in the AF compared with control tissues. There was strong correlation among the CXCR4, TYROBP and AF based on the BP neural network. Through training, best training performance is 9.6474e‐05 at epoch 14, and the relativity was 0.99998. CXCR4 and TYROBP might be involved in the development of atrial fibrillation by affecting inflammation‐related signalling pathways and may serve as targets for early diagnosis and preventive treatment.

A bstract We revisit the condensation scenario of charged pions in external magnetic field and rotation, which was first considered by Y. Liu and I. Zahed. Based on the Ginzburg-Landau analysis of the Nambu-Jona-Lasinio model, we find that the charged-pion condensation takes place only when both a strong coupling constant and negatively large baryon chemical potential are applied. Besides, our numerical calculation shows that the chiral restoration induced by the interplay between magnetic field and rotation (i.e., the rotational magnetic inhibition) interrupts the formation of the charged-pion condensate. This suggests that the analysis of such condensation requires a careful treatment of the inner structure of pions, which was not taken into account before. We also discuss the underlying physical mechanism of our finding and the indication of charged-rho condensation.

Chronic stress refers to the non-specific systemic reaction that occurs when the body is stimulated by various internal and external negative factors over a long time. The physiological response to chronic stress exposure has long been recognized as a potent modulator in the occurrence of atherosclerosis. Furthermore, research has confirmed the correlation between atherosclerosis and cardiovascular events. Chronic stress is pervasive during negative life events and may lead to the formation of plaque. Several epidemiological studies have shown that chronic stress is an independent risk factor for the development of vascular disease and for increased morbidity and mortality in patients with pre-existing coronary artery disease. One possible mechanism for this process is that chronic stress causes endothelial injury, directly activating macrophages, promoting foam cell formation and generating the formation of atherosclerotic plaque. This mechanism involves numerous variables, including inflammation, signal pathways, lipid metabolism and endothelial function. The mechanism of chronic stress in atherosclerosis should be further investigated to provide a theoretical basis for efforts to eliminate the effect of chronic stress on the cardiocerebral vascular system.

Cardiac hypertrophy is a significant risk factor for cardiovascular disease, including heart failure, arrhythmia, and sudden death. Cardiac hypertrophy involves both embryonic gene expression and transcriptional reprogramming, which are tightly regulated by epigenetic mechanisms. An increasing number of studies have demonstrated that epigenetics plays an influential role in the occurrence and development of cardiac hypertrophy. Here, we summarize the latest research progress on epigenetics in cardiac hypertrophy involving DNA methylation, histone modification, and non-coding RNA, to help understand the mechanism of epigenetics in cardiac hypertrophy. The expression of both embryonic and functional genes can be precisely regulated by epigenetic mechanisms during cardiac hypertrophy, providing a substantial number of therapeutic targets. Thus, epigenetic treatment is expected to become a novel therapeutic strategy for cardiac hypertrophy. According to the research performed to date, epigenetic mechanisms associated with cardiac hypertrophy remain far from completely understood. Therefore, epigenetic mechanisms require further exploration to improve the prevention, diagnosis, and treatment of cardiac hypertrophy.

HighlightsA self-powered liquid–solid interface ferrofluid-based triboelectric tactile sensor with immediately formed spike-shaped microstructure is proposed.Due to the high spike microstructure, low Young’s modulus of ferrofluid and efficient solid–liquid interface contact-electrification, an ultrahigh sensitivity of 21.48 kPa−1 for the triboelectric sensors can be achieved.A strategy for personalized password lock with high security level is demonstrated.Traditional triboelectric tactile sensors based on solid–solid interface have illustrated promising application prospects through optimization approach. However, the poor sensitivity and reliability caused by hard contact-electrification still poses challenges for the practical applications. In this work, a liquid–solid interface ferrofluid-based triboelectric tactile sensor (FTTS) with ultrahigh sensitivity is proposed. Relying on the fluidity and magnetism of ferrofluid, the topography of microstructure can be flexibly adjusted by directly employing ferrofluid as triboelectric material and controlling the position of outward magnet. To date, an ultrahigh sensitivity of 21.48 kPa−1 for the triboelectric sensors can be achieved due to the high spike microstructure, low Young’s modulus of ferrofluid and efficient solid–liquid interface contact-electrification. The detection limit of FTTS of 1.25 Pa with a wide detection range to 390 kPa was also obtained. In addition, the oleophobic property between ferrofluid and poly-tetra-fluoro-ethylene triboelectric layer can greatly reduce the wear and tear, resulting in the great improvement of stability. Finally, a strategy for personalized password lock with high security level has been demonstrated, illustrating a great perspective for practical application in smart home, artificial intelligence, Internet of things, etc.