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Economy for and against democracy (The human economy; volume 2)
Political constitutions alone do not guarantee democracy; a degree of economic equality is also essential. Yet contemporary economies, dominated as they are by global finance and political rent-seekers, often block the realization of democracy. The comparative essays and case studies of this volume examine the contradictory relationship between the economy and democracy and highlight the struggles and visions needed to make things more equitable. They explore how our collective aspirations for greater democracy might be informed by serious empirical research on the human economy today. If we want a better world, we must act on existing social realities.
eBook
Money in a human economy
A human economy puts people first in emergent world society. Money is a human universal and now takes the divisive form of capitalism. This book addresses how to think about money (from Aristotle to the daily news and the sexual economy of luxury goods); its contemporary evolution (banking the unbanked and remittances in the South, cross-border investment in China, the payments industry and the politics of bitcoin); and cases from 19th century India and Southern Africa to contemporary Haiti and Argentina. Money is one idea with diverse forms. As national monopoly currencies give way to regional and global federalism, money is a key to achieving economic democracy.
eBook
People, money and power in the economic crisis
The Cold War was fought between \"state socialism\" and \"the free market.\" That fluctuating relationship between public power and private money continues today, unfolding in new and unforeseen ways during the economic crisis. Nine case studies -- from Southern Africa, South Asia, Brazil, and Atlantic Africa - examine economic life from the perspective of ordinary people in places that are normally marginal to global discourse, covering a range of class positions from the bottom to the top of society. The authors of these case studies examine people's concrete economic activities and aspirations. By looking at how people insert themselves into the actual, unequal economy, they seek to reflect human unity and diversity more fully than the narrow vision of conventional economics.
eBook
A pilot study investigating the efficacy of technology enhanced case based learning (CBL) in small group teaching
The recent paradigm shift in teaching provision within higher education, following the COVID-19 pandemic, has led to blended models of learning prevailing in the pedagogic literature and in education practice. This shift has also resulted in an abundance of tools and technologies coming to market. Whilst the value of integrating technology into teaching and assessment has been well-established in the literature, the magnitude of choice available to educators and to students can be overwhelming. The current pilot investigated the feasibility of integrating key technologies in delivering technology-enhanced learning (TEL) case-based learning (CBL) within a sample of year two medical students. The cohort was selected at random, as was the control group receiving conventional CBL. Both groups were matched on prior academic performance. The TEL-CBL group received (1) in-person tutorials delivered within an immersive learning suite, (2) access to 3D anatomy software to explore during their self-directed learning time, (3) virtual reality (VR) guided anatomy exploration during tutorials, (4) access to a generative AI-based simulated virtual patient repository to practice key skills such as communication and history taking, and (5) an immersive medical emergency simulation. Metrics assessed included formative academic performance, student learning experience, and confidence in relation to communication and clinical skills. The results revealed that the TEL-CBL group outperformed their peers in successive formative assessments (
p
< 0.05), engaged thoroughly with the technologies at their disposal, and reported that these technologies enhanced their learning experience. Furthermore, students reported that access to the GenAI-simulated virtual patient platform and the immersive medical emergency simulation improved their clinical confidence and gave them a useful insight into what they can expect during the clinical phase of their medical education. The results are discussed in relation to the advantages that key emerging technologies may play in enhancing student performance, experience and confidence.
Journal Article
Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation
Aminophospholipid (APL) trafficking across the plasma membrane is a key event in cell activation, apoptosis, and aging and is required for clearance of dying cells and coagulation. Currently the phospholipid molecular species externalized are unknown. Using a lipidomic method, we show that thrombin, collagen, or ionophore-activated human platelets externalize two phosphatidylserines (PSs) and five phosphatidylethanolamines (PEs). Four percent of the total cellular PE/PS pool (∼300 ng/2 × 10 ⁸ cells, thrombin), is externalized via calcium mobilization and protease-activated receptors-1 and -4, and 48% is contained in microparticles. Apoptosis and energy depletion (aging) externalized the same APLs in a calcium-dependent manner, and all stimuli externalized oxidized phospholipids, termed hydroxyeicosatetraenoic acid-PEs. Transmembrane protein-16F (TMEM-16F), the protein mutated in Scott syndrome, was required for PE/PS externalization during thrombin activation and energy depletion, but not apoptosis. Platelet-specific APLs optimally supported tissue factor-dependent coagulation in human plasma, vs. APL with longer or shorter fatty acyl chains. This finding demonstrates fatty acids as molecular determinants of APL that regulate hemostasis. Thus, the molecular species of externalized APL during platelet activation, apoptosis, and energy depletion were characterized, and their ability to support coagulation revealed. The findings have therapeutic implications for bleeding disorders and transfusion therapy. The assay could be applied to other cell events characterized by APL externalization, including cell division and vesiculation.
Journal Article
Leptospirosis in the Platypus (Ornithorhynchus anatinus) in Australia: Who Is Infecting Whom?
The platypus (Ornithorhynchus anatinus) is an amphibious, egg-laying mammal of high conservation value that is found only in Australia. The zoonotic bacterium Leptospira interrogans serovar Hardjo was discovered in platypuses in prior studies, but little is known about its epidemiology. Samples in the Platypus Serum Bank were tested in 2023 and the results were combined with historical records. Antibodies against L. interrogans serovar Hardjo were found in 50% of 464 serum samples from 411 platypuses collected from 14 river basins in southeastern Australia between 1981 and 2012; prevalence remained high over three decades in the Shoalhaven River population. Seroprevalence increased with age, suggesting environmental exposure. Individual platypuses had persistent titres, some for six years. Seropositive females lactated, juveniles were recruited into the population, and there were no reports of clinical leptospirosis. Three necropsied platypuses were seropositive and had mild nephritis with leptospires in the renal tubules. The high seroprevalence, persistent titres, lack of disease, mild renal lesions, and renal colonisation suggest the platypus may be a maintenance host. Sympatric cattle had L. interrogans serovar Hardjo titres, but the spatial association with seropositive platypuses was statistically weak. Other mammalian wildlife species and sheep also have L. interrogans serovar Hardjo titres; therefore, a complex ecological network must be considered. A landscape-wide study is recommended to properly assess transmission pathways and confirm who is infecting whom.
Journal Article
