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"Hess, Erik P."
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Increased Computed Tomography Utilization in the Emergency Department and Its Association with Hospital Admission
2017
Our goal was to investigate trends in computed tomography (CT) utilization in emergency departments (EDs) and its association with hospitalization.
We conducted an analysis of an administrative claims database of U.S. privately insured and Medicare Advantage enrollees. We identified ED visits from 2005 through 2013 and assessed for CT use, associated factors, and hospitalization after CT, along with patient demographics. We used both descriptive methods and regression models adjusted for year, age, sex, race, geographic region, and Hwang comorbidity score to explore associations among CT use, year, demographic characteristics, and hospitalization.
We identified 33,144,233 ED visits; 5,901,603 (17.8%) involved CT. Over time, CT use during ED visits increased 59.9%. CT use increased in all age groups but decreased in children since 2010. In propensity-matching analysis, odds of hospitalization increased with age, comorbidities, male sex, and CT use (odds ratio, 2.38). Odds of hospitalization over time decreased more quickly for patients with CT.
CT utilization in the ED has increased significantly from 2005 through 2013. For children, CT use after 2010 decreased, indicating caution about CT use. Male sex, older age, and higher number of comorbidities were predictors of CT in the ED. Over time, odds of hospitalization decreased more quickly for patients with CT.
Journal Article
The association between specific narrative elements and patient perspectives on acute pain treatment
by
Bellamkonda, Venkatesh R.
,
Becker, Lance B.
,
Shofer, Frances S.
in
Acute Pain - drug therapy
,
Addictions
,
Adolescent
2023
Narratives are effective tools for communicating with patients about opioid prescribing for acute pain and improving patient satisfaction with pain management. It remains unclear, however, whether specific narrative elements may be particularly effective at influencing patient perspectives.
This study was a secondary analysis of data collected for Life STORRIED, a multicenter RCT. Participants included 433 patients between 18 and 70 years-old presenting to the emergency department (ED) with renal colic or musculoskeletal back pain. Participants were instructed to view one or more narrative videos during their ED visit in which a patient storyteller discussed their experiences with opioids. We examined associations between exposure to individual narrative features and patients' 1) preference for opioids, 2) recall of opioid-related risks and 3) perspectives about the care they received.
Participants were more likely to watch videos featuring storytellers who shared their race or gender. We found that participants who watched videos that contained specific narrative elements, for example mention of prescribed opioids, were more likely to recall having received information about pain treatment options on the day after discharge (86.3% versus 72.9%, p = 0.02). Participants who watched a video that discussed family history of addiction reported more participation in their treatment decision than those who did not (7.6 versus 6.8 on a ten-point scale, p = 0.04).
Participants preferentially view narratives featuring storytellers who share their race or gender. Narrative elements were not meaningfully associated with patient-centered outcomes. These findings have implications for the design of narrative communication tools.
Journal Article
Shared decision-making for pediatric acute otitis media in the United States: a randomized emergency department trial
by
Hargraves, Ian G.
,
Mullan, Aidan
,
Bellolio, Fernanda
in
Acute Disease
,
Acute otitis media
,
Adult
2025
Background
Shared decision-making is increasingly utilized when multiple reasonable options exist. In the emergency department, however, several perceived barriers—such as time constraints, illness complexity, and varying levels of acceptance—limit its use. In cases of acute otitis media (AOM) in children, parental expectations for immediate antibiotic treatment often conflict with national guidelines recommending a trial of analgesics for 48 to 72 h prior to initiating antibiotics. As a result, antibiotic prescribing rates in the emergency department remain high, reaching up to 96%. Our aim was to measure the impact of the ear pain decision aid on parental knowledge, engagement and antibiotic use.
Methods
We conducted a randomized trial in the Emergency Department and affiliated Urgent Care setting comparing shared decision-making with a web-based decision aid (earpaindecisionaid.org) to usual care for parents of children aged 6 months and older with non-severe AOM. Outcomes included parental knowledge of AOM, clinician/parent engagement, interaction time, and antibiotic use.
Results
One hundred-one parents were enrolled; 42 participated in the Ear Pain Decision Aid (EPDA) arm using shared decision-making, while 59 received usual care (UC). Fifty-one interactions were videotaped. Parents in the EPDA arm scored greater in knowledge: EPDA 6.1 (1.74) vs. UC 5.1 (1.79), mean difference 1.0 (95% CI 0.3, 1.7),
p
= 0.004. They also scored high in decision-making: EPDA 14.7 (2.86) vs. UC 8.75 (3.68), mean difference 6.0 (95% CI 1.9, 10.0),
p
= 0.005. There was no significant difference in interaction time: EPDA 4.2 min (3.2, 5.6) vs. UC 3.0 min (2.4, 4.4),
p
= 0.059. No difference was detected in immediate antibiotic prescriptions: EPDA 36% vs. UC 42%, odds ratio 0.76 (95% CI 0.33, 1.71),
p
= 0.50. Similarly, no significant difference was found in wait-and-see prescription use: EPDA 64% vs. UC 6a8%, odds ratio 1.32 (95% CI 0.59, 2.99),
p
= 0.50.
Conclusion
Shared decision-making with the Ear Pain Decision Aid (EPDA) improved parental knowledge and engagement without significantly increasing interaction time in the emergency department. Although no significant reduction in antibiotic prescribing was observed, this may be due to the study’s limited sample size, which increases the risk of Type II error. These findings support the feasibility of integrating shared decision-making tools into emergency care. Larger, multicenter studies are needed to further evaluate the EPDA’s effectiveness in promoting antibiotic stewardship for pediatric acute otitis media.
Clinical trials number
NCT02872558 26/03/2017.
Journal Article
Access to primary care and computed tomography use in the emergency department
by
Bellolio, M. Fernanda
,
Jeffery, Molly M.
,
Sangaralingham, Lindsey R.
in
Access control
,
CAT scans
,
Diagnostic imaging
2018
Background
The decision to obtain a computed tomography CT scan in the emergency department (ED) is complex, including a consideration of the risk posed by the test itself weighed against the importance of obtaining the result. In patients with limited access to primary care follow up the consequences of not making a diagnosis may be greater than for patients with ready access to primary care, impacting diagnostic reasoning. We set out to determine if there is an association between CT utilization in the ED and patient access to primary care.
Methods
We performed a cross-sectional study of all ED visits in which a CT scan was obtained between 2003 and 2012 at an academic, tertiary-care center. Data were abstracted from the electronic medical record and administrative databases and included type of CT obtained, demographics, comorbidities, and access to a local primary care provider (PCP). CT utilization rates were determined per 1000 patients.
Results
A total of 595,895 ED visits, including 98,001 visits in which a CT was obtained (16.4%) were included. Patients with an assigned PCP accounted for 55% of all visits. Overall, CT use per 1000 ED visits increased from 142.0 in 2003 to 169.2 in 2012 (
p
< 0.001), while the number of annual ED visits remained stable. CT use per 1000 ED visits increased from 169.4 to 205.8 over the 10-year period for patients without a PCP and from 118.9 to 142.0 for patients with a PCP. Patients without a PCP were more likely to have a CT performed compared to those with a PCP (OR 1.57, 95%CI 1.54 to 1.58;
p
< 0.001). After adjusting for age, gender, year of visit and number of comorbidities, patients without a PCP were more likely to have a CT performed (OR 1.20, 95% CI 1.18 to 1.21,
p
< 0.001).
Conclusions
The overall rate of CT utilization in the ED increased over the past 10 years. CT utilization was significantly higher among patients without a PCP. Increased availability of primary care, particularly for follow-up from the ED, could reduce CT utilization and therefore decrease costs, ED lengths of stay, and radiation exposure.
Journal Article
Diagnostic accuracy of the TIMI risk score in patients with chest pain in the emergency department: a meta-analysis
by
Erwin, Patricia J.
,
Hollander, Judd E.
,
Murad, Mohammed H.
in
Aged
,
Care and treatment
,
Chest pain
2010
The Thrombolysis in Myocardial Infarction (TIMI) risk score uses clinical data to predict the short-term risk of acute myocardial infarction, coronary revascularization or death from any cause. It was originally developed for use in patients with unstable angina or non-ST-elevation myocardial infarction. We sought to expand the clinical application of the TIMI risk score by assessing its prognostic accuracy in patients in the emergency department with potential acute coronary syndromes.
We searched five electronic databases, hand-searched reference lists of included studies and contacted content experts to identify articles for review. We included prospective cohort studies that validated the TIMI risk score in emergency department patients. We performed a meta-regression to determine whether a linear relation exists between TIMI risk score and the cumulative incidence of cardiac events.
We included 10 prospective cohort studies (with a total of 17 265 patients) in our systematic review. Data were available for meta-analysis in 8 of the 10 studies. Of patients with a score of zero, 1.8% had a cardiac event within 30 days (sensitivity 97.2%, 95% CI 96.4-97.8; specificity 25.0%, 95% CI 24.3-25.7; positive likelihood ratio 1.30, 95% CI 1.28-1.31; negative likelihood ratio 0.11, 95% CI 0.09-0.15). Meta-regression analysis revealed a strong linear relation between TIMI risk score (p < 0.001) and the cumulative incidence of cardiac events.
Although the TIMI risk score is an effective risk stratification tool for patients in the emergency department with potential acute coronary syndromes, it should not be used as the sole means of determining patient disposition.
Journal Article
Feasibility and efficacy of a decision aid for emergency department patients with suspected ureterolithiasis: protocol for an adaptive randomized controlled trial
2021
Background
Approximately 2 million patients present to emergency departments in the USA annually with signs and symptoms of ureterolithiasis (or
renal colic
, the pain from an obstructing kidney stone). Both ultrasound and CT scan can be used for diagnosis, but the vast majority of patients receive a CT scan. Diagnostic pathways utilizing ultrasound have been shown to decrease radiation exposure to patients but are potentially less accurate. Because of these and other trade-offs, this decision has been proposed as appropriate for Shared Decision-Making (SDM), where clinicians and patients discuss clinical options and their consequences and arrive at a decision together. We developed a decision aid to facilitate SDM in this scenario. The objective of this study is to determine the effects of this decision aid, as compared to usual care, on patient knowledge, radiation exposure, engagement, safety, and healthcare utilization.
Methods
This is the protocol for an adaptive randomized controlled trial to determine the effects of the intervention—a decision aid (“Kidney Stone Choice”)—on patient-centered outcomes, compared with usual care. Patients age 18–55 presenting to the emergency department with signs and symptoms consistent with acute uncomplicated ureterolithiasis will be consecutively enrolled and randomized. Participants will be blinded to group allocation. We will collect outcomes related to patient knowledge, radiation exposure, trust in physician, safety, and downstream healthcare utilization.
Discussion
We hypothesize that this study will demonstrate that “Kidney Stone Choice,” the decision aid created for this scenario, improves patient knowledge and decreases exposure to ionizing radiation. The adaptive design of this study will allow us to identify issues with fidelity and feasibility and subsequently evaluate the intervention for efficacy.
Trial registration
ClinicalTrials.gov
NCT04234035
. Registered on 21 January 2020 – Retrospectively Registered
Journal Article
What is the effect of a decision aid in potentially vulnerable parents? Insights from the head CT choice randomized trial
by
Cohen, Daniel M.
,
Nigrovic, Lise E.
,
Westphal, Jessica J.
in
Adolescent
,
Brain damage
,
Brain injured children
2020
Objective To test the hypotheses that use of the Head CT Choice decision aid would be similarly effective in all parent/patient dyads but parents with high (vs low) numeracy experience a greater increase in knowledge while those with low (vs high) health literacy experience a greater increase in trust. Methods This was a secondary analysis of a cluster randomized trial conducted at seven sites. One hundred seventy‐two clinicians caring for 971 children at intermediate risk for clinically important traumatic brain injuries were randomized to shared decision making facilitated by the DA (n = 493) or to usual care (n = 478). We assessed for subgroup effects based on patient and parent characteristics, including socioeconomic status (health literacy, numeracy and income). We tested for interactions using regression models with indicators for arm assignment and study site. Results The decision aid did not increase knowledge more in parents with high numeracy (P for interaction [Pint] = 0.14) or physician trust more in parents with low health literacy (Pint = 0.34). The decision aid decreased decisional conflict more in non‐white parents (decisional conflict scale, −8.14, 95% CI: −12.33 to −3.95; Pint = 0.05) and increased physician trust more in socioeconomically disadvantaged parents (trust in physician scale, OR: 8.59, 95% CI: 2.35‐14.83; Pint = 0.04). Conclusions Use of the Head CT Choice decision aid resulted in less decisional conflict in non‐white parents and greater physician trust in socioeconomically disadvantaged parents. Decision aids may be particularly effective in potentially vulnerable parents.
Journal Article
Clinicians' perspectives on the implementation of patient decision aids in the emergency department: A qualitative interview study
by
Chang, Bernard P., MD, PhD
,
Billah, Tausif, MD
,
Schoenfeld, Elizabeth M., MD, MS
in
chest pain
,
Clinical medicine
,
decision aid
2022
AbstractObjectiveDecision aids (DAs) are tools to facilitate and standardize shared decision making (SDM). Although most emergency clinicians (ECs) perceive SDM appropriate for emergency care, there is limited uptake of DAs in clinical practice. The objective of this study was to explore barriers and facilitators identified by ECs regarding the implementation of DAs in the emergency department (ED). MethodsWe conducted a qualitative interview study guided by implementation science frameworks. ECs participated in interviews focused on the implementation of DAs for the disposition of patients with low‐risk chest pain and unexplained syncope in the ED. Interviews were recorded and transcribed verbatim. We then iteratively developed a codebook with directed qualitative content analysis. ResultsWe approached 25 ECs working in urban New York, of whom 20 agreed to be interviewed (mean age, 41 years; 25% women). The following 6 main barriers were identified: (1) poor DA accessibility, (2) concern for increased medicolegal risk, (3) lack of perceived need for a DA, (4) patient factors including lack of capacity and limited health literacy, (5) skepticism about validity of DAs, and (6) lack of time to use DAs. The 6 main facilitators identified were (1) positive attitudes toward SDM, (2) patient access to follow‐up care, (3) potential for improved patient satisfaction, (4) potential for improved risk communication, (5) strategic integration of DAs into the clinical workflow, and (6) institutional support of DAs. ConclusionsECs identified multiple barriers and facilitators to the implementation of DAs into clinical practice. These findings could guide implementation efforts targeting the uptake of DA use in the ED.
Journal Article
Evaluating patients with chest pain in the emergency department
by
Body, Richard
,
Gottlieb, Michael
,
Bellolio, Fernanda
in
Acute Coronary Syndrome - blood
,
Acute Coronary Syndrome - diagnosis
,
Acute coronary syndromes
2025
AbstractIdentifying patients with chest pain that is of cardiac origin is crucial owing to the high mortality and morbidity of cardiovascular diseases. History, electrocardiogram, and cardiac biomarkers are the core elements of the assessment. High sensitivity cardiac troponins (hs-cTn) are the preferred biomarkers for diagnosing acute myocardial infarction, allowing for more accurate detection and exclusion of myocardial injury. However, elevations in hs-cTn can occur in patients who are not experiencing acute myocardial infarction. Therefore, it is important for clinicians to recognize how to integrate hs-cTn levels into their clinical decision making process. Structured risk assessments, using evidence based diagnostic protocols, should be employed to estimate the risk of acute coronary syndrome and adverse events in patients with chest pain. Clinical decision pathways should be used routinely in emergency departments. Patients at intermediate or high risk of obstructive coronary artery disease might benefit from cardiac imaging and further testing. Patients should be involved in decision making, with information provided about risks, radiation exposure, costs, and alternative options to facilitate informed decision making.
Journal Article
External validation of the Glasgow-Blatchford Bleeding Score and the Rockall Score in the US setting
by
Song, Louis M. Wong Kee
,
Chandra, Subhash
,
Wells, George A.
in
Aged
,
Aged, 80 and over
,
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
2012
The Glasgow-Blatchford Bleeding Score (GBS) and Rockall Score (RS) are clinical decision rules that risk stratify emergency department (ED) patients with upper gastrointestinal bleeding (UGIB). We evaluated GBS and RS to determine the extent to which either score identifies patients with UGIB who could be safely discharged from the ED.
We reviewed and extracted data from the electronic medical records of consecutive adult patients who presented with signs or symptoms of UGIB (hematemesis and/or melena) to an academic ED from April 1, 2004, to April 1, 2009. The primary outcome was need for intervention (blood transfusion and/or endoscopic/surgical intervention) or death within 30 days.
We identified 171 patients with the following characteristics: mean age of 69.9 years (SD, 17.0 years ), 52% women, 20% with a history of liver disease, and 22% with history of gastrointestinal bleeding. Ninety (52.6%, 95% confidence interval, 44.9-60.3) patients had the primary outcome. GBS outperformed pre-endoscopy RS [area under the receiver operating characteristic curve (AUC) = 0.79 vs 0.62; P = .0001; absolute difference, 0.17]. The prognostic accuracy of GBS and post-endoscopy RS was similarly high (AUC, 0.79 vs 0.72; P = .26; absolute difference, 0.07). The specificity of GBS and RS was suboptimal at all potential decision thresholds.
Although GBS outperformed pre-endoscopy RS, the prognostic accuracy of GBS and post-endoscopy RS was similarly high. The specificity of GBS and RS was insufficient to recommend use of either score in clinical practice.
Journal Article