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"Hillis, W. Daniel"
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The pattern on the stone : the simple ideas that make computers work
Danny Hillis offers a clear, easy-to-understand explanation of how computers perform their amazing feats.
eBook
The Pattern On The Stone
Danny Hillis offers a clear, easy-to-understand explanation of how computers perform their amazing feats.
eBook
A physical sciences network characterization of non-tumorigenic and metastatic cells
To investigate the transition from non-cancerous to metastatic from a physical sciences perspective, the Physical Sciences–Oncology Centers (PS-OC) Network performed molecular and biophysical comparative studies of the non-tumorigenic MCF-10A and metastatic MDA-MB-231 breast epithelial cell lines, commonly used as models of cancer metastasis. Experiments were performed in 20 laboratories from 12 PS-OCs. Each laboratory was supplied with identical aliquots and common reagents and culture protocols. Analyses of these measurements revealed dramatic differences in their mechanics, migration, adhesion, oxygen response and proteomic profiles. Model-based multi-omics approaches identified key differences between these cells' regulatory networks involved in morphology and survival. These results provide a multifaceted description of cellular parameters of two widely used cell lines and demonstrate the value of the PS-OC Network approach for integration of diverse experimental observations to elucidate the phenotypes associated with cancer metastasis.
Journal Article
What Is Massively Parallel Computing, and Why Is It Important?
Massively parallel computing will bring economies of scale to information processing, just as mass production created new economies in manufacturing. Pipelining, functional parallelism and data parallelism are discussed.
Journal Article
Intelligence as an Emergent Behavior; Or, the Songs of Eden
A hypothetical portrayal of what the world would be like if intelligence were an emergent behavior of randomly connected neurons. References included.
Journal Article