Explore the vast range of titles available.

Addressing the urgent need for sustainable transformation in higher education, this paper explores how a collaborative action research group of teacher educators from different institutions contributed to higher education transformation through sustainable education approaches. Drawing on cultural–historical activity theory (CHAT), we analyze how cross-institutional partnerships fostered personal and professional development through digital collaboration, regular online meetings, and reflective dialogue. The study employed participatory action research, using weekly reflective journals and group meetings as mediating tools supporting sustained professional learning. Findings indicate that building common ground across institutional contexts and investing in trust-building cultivated a meaningful collaborative environment, a “third space” that mediated expansive learning and professional transformation. Within this space, the diversity of institutional backgrounds enriched the activity system, and productive contradictions served as generative mechanisms that catalyze expansive learning by exposing participants to diverse institutional perspectives. The study further shows that sustainable collaboration emerged not from formal institutional structures but from shared ownership, cultural alignment, and relational commitment. These social and cultural processes supported the development of systems-thinking, strategic-thinking, and interpersonal competencies supporting sustainable professional development. The study highlights the potential of sustainable cross-institutional spaces as a model for professional growth in higher education.

Exposure to high ambient temperature is a stressor that influences both biological and behavioral functions and has been previously shown to have an extensive impact on brain structure and function. Physiological, cellular and behavioral responses to heat-stress (HS) (40-41 °C, 2 h) were evaluated in adult male rats. The effect of HS exposure before predator-scent stress (PSS) exposure (i.e., HS preconditioning) was examined. Finally, a possible mechanism of HS-preconditioning to PSS was investigated. Immunohistochemical analyses of chosen cellular markers were performed in the hippocampus and in the hypothalamic paraventricular nucleus (PVN). Plasma corticosterone levels were evaluated, and the behavioral assessment included the elevated plus-maze (EPM) and the acoustic startle response (ASR) paradigms. Endogenous levels of heat shock protein (HSP)-70 were manipulated using an amino acid (L-glutamine) and a pharmacological agent (Doxazosin). A single exposure to an acute HS resulted in decreased body mass (BM), increased body temperature and increased corticosterone levels. Additionally, extensive cellular, but not behavioral changes were noted. HS-preconditioning provided behavioral resiliency to anxiety-like behavior associated with PSS, possibly through the induction of HSP-70. Targeting of HSP-70 is an attractive strategy for stress-related psychopathology treatment.

The long form of the dopamine D4 receptor (D4DR) exon III repeat polymorphism has been linked in some but not all studies to impulsive, extravagant and novelty‐seeking personality traits that are prominent in affiliated behaviours such as attention deficit disorder and substance abuse. In particular, we have reported previously an increased frequency of the long seven‐repeat D4DR exon III allele in a group of 141 opioiddependent subjects compared to 110 control subjects. In order to further substantiate the role of D4DR in contributing to heroin addiction we have genotyped an additional, smaller cohort of opioid‐dependent subjects. In this new group of 57 opioid‐dependent subjects compared to an expanded group of 143 control subjects a significant difference was observed in overall genotype frequency (p=0.04). An excess of the seven‐repeat allele of the D4DR receptor gene was also observed compared to control subjects (p=0.06). The frequency of the seven‐repeat allele is 15.8% in the heroin addict population vs. 8.1% in the control group, conferring a relative risk of 2.07 (95% CI: 0.98–4.38). An association between two polymorphisms considered together (D4DR and dopamine D3 receptor) and treatment retention was observed (p=0.02). In a subgroup of 38 opioid‐dependent subjects, who were successfully administered the TPQ, higher Harm Avoidance (p< 0.001) and Novelty Seeking (NS3; extravagant vs. reserved, p< 0.001) scores were found. In contrast to some previous reports, no relationship was apparent between TPQ scores and treatment retention in this small group of opioid‐dependent subjects.