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هدفت الدراسة إلى التعرف على درجة تطبيق أبعاد التجديد الاستراتيجي وعلاقته في تحقيق الريادة المؤسسية في الجامعات الخاصة في محافظة العاصمة عمان من وجهة نظر أعضاء هيئة التدريس. استخدام المنهج الوصفي الارتباطي، وتم جمع البيانات من خلال تطبيق استبانة على عينة مكونة من (٢٨٠) عضو هيئة تدريس تم اختيارهم عشوائيا من أربع جامعات خاصة في العاصمة عمان تم اختيارها بالطريقة القصدية. أظهرت نتائج الدراسة أن درجة تطبيق التجديد الاستراتيجي في الجامعات الخاصة بمحافظة العاصمة عمان جاءت مرتفعة، وأن درجة تحقيق الريادة المؤسسية جاءت مرتفعة، كما أظهرت الدراسة أن هناك علاقة ارتباطية ذات دلالة إحصائية بين درجة تطبيق التجديد الاستراتيجي ودرجة تحقيق الريادة المؤسسية. وأوصت الدراسة الاستمرار في عقد الدورات والورش التدريبية ذات العلاقة بمجالات التجديد الاستراتيجي؛ لأهميتها في تحقيق الريادة المؤسسية في الجامعات، وإجراء دراسات مماثلة في الجامعات الحكومية، ومقارنة نتائجها مع الدراسة الحالية.

Key Clinical Message Gastrointestinal stromal tumors are the most common malignant subepithelial lesions involving the gastrointestinal tract. Surgical techniques have been the mainstay of treatment, however, in recent times hybrid surgeries are being introduced yielding better clinical outcomes.

Acne vulgaris is a common skin condition that significantly impacts both physical appearance and mental well-being. Acne, being a chronic skin condition, often requires continuous treatment. This study aims to evaluate the efficacy and safety of clindamycin phosphate 1.2%/benzoyl peroxide 3% compared to clindamycin phosphate 1.2%/adapalene 0.1% combinations for treating acne vulgaris. A systematic review and meta-analysis of randomized controlled trials were carried out following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, and three databases were searched to identify RCTs comparing CLIN/BPO with CLIN/ADAP. Primary outcomes included treatment-emergent adverse events, inflammatory and non-inflammatory lesion counts, and application site side effects. Statistical analyses were conducted using RevMan 5.3. The study included a total of 800 participants across three RCTs. The meta-analysis of three RCTs demonstrated a significantly lower risk of TEAEs with CLIN/BPO (OR = 0.49, 95% CI: 0.35–0.86, p  < 0.001). CLIN/BPO also resulted in fewer application site side effects (OR = 0.33, 95% CI: 0.23–0.47, p  < 0.001). However, no significant differences were observed between the groups for reducing inflammatory (MD = 1.34, 𝑝 = 0.121) or non-inflammatory lesion counts (MD = 0.04, 𝑝 = 0.98). The study concluded that although CLIN/BPO was associated with fewer side effects, both treatments were equally effective in reducing acne lesions. The favorable safety profile of CLIN/BPO, particularly regarding treatment-emergent and application-site adverse events, suggests it may be the more tolerable option for patients. Future studies with larger, more diverse populations are recommended to confirm these findings and explore long-term efficacy.

Background/Objectives: Oral Lichen Planus (OLP) is a common immune-mediated inflammatory disorder affecting the oral mucosa, impacting 0.5% to 2% of the global population, primarily middle-aged women. Immunological dysregulation is a key factor in OLP’s pathogenesis, involving CD4+ T helper and CD8+ T cytotoxic cells. The World Health Organization (WHO) classifies OLP as a potentially malignant disorder, with a risk of oral squamous cell carcinoma (OSCC) developing in up to 2% of lesions. This narrative review aims to provide a comprehensive overview of the etiopathogenesis, clinical manifestations, diagnostic criteria, and therapeutic strategies for OLP, informing clinical practice and guiding future research. Methods: A review of the literature from the PubMed and Google Scholar databases was conducted up to December 2023, focusing on studies addressing the etiopathogenesis, diagnosis, clinical manifestations, and treatment of OLP. Results: OLP’s pathogenesis is driven by immune dysregulation, with CD4+ and CD8+ cells playing crucial roles. Clinically, OLP presents as reticular, erosive, bullous, and plaque-like lesions. Diagnosis relies on clinical examination, histopathology, and direct immunofluorescence. Recent advancements in diagnostic markers and imaging techniques have improved detection and monitoring. Treatment primarily involves corticosteroids, but novel therapies such as curcumin, retinoids, and laser therapy are increasingly used for their effectiveness and reduced side effects. These treatments show promise in symptom reduction and recurrence prevention, although long-term data are needed. Conclusions: Regular screenings and biopsies are essential due to OLP’s likelihood of malignant transformation. This study urges further investigation into long-term results, improved diagnostic techniques, and evidence-based treatment regimens.

To determine the prevalence of impetigo among children in Saudi Arabia as well as to identify socio-demographic factors associated with impetigo. This cross-sectional study conducted in Saudi Arabia examined impetigo prevalence and associated factors among children aged 2 to 15. Data collection occurred between June 2022 and November 2023, involving structured interviews with the parents or legal guardians of the participating children. A pre-designed questionnaire was used, which included questions related to personal hygiene practices (such as, frequency of handwashing, bathing routines, and use of communal facilities), environmental conditions, and the child's impetigo diagnosis history. The study encompassed a total of 1200 participants, with a predominant representation of female (79.3%). Participants exhibited a diverse age distribution, with the highest proportion falling within the 18-24 age group (33.7%). Importantly, a statistically significant association was identified between the occurrence of impetigo in children and their personal hygiene scores (p < 0.001). Children with a confirmed impetigo diagnosis exhibited lower mean personal hygiene scores (2.6 ± 0.723) in contrast to those without such diagnoses (3.75 ± 0.911). Socio-demographic factors, including child's gender, parental education level, employment status, and geographic location, emerge as significant determinants of impetigo occurrence. Additionally, there is a strong correlation between proper personal hygiene practices and a reduced incidence of impetigo.

Key Clinical Message Spindle cell lipoma is a histological variant of oral lipomas. In this report, we present the first case from the Gulf region with the most comprehensive literature review. Clinicians should consider rare tumors in the differential diagnoses of oral masses. Histopathology of the resected specimen denoting (a) Spindle cell lipoma containing a mixture of adipocytes, bland spindle cells and rubbery collagen fiber. (b) Benign adipocytic neoplasm showed muscle at the periphery. (c) Low power view of benign adipocytic neoplasm with bland spindle cells.