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The first full-length work to use prominent accounts of globalization to examine contemporary poetry written in English.Offers accessible readings of poetic form and of the contemporary political economy and sociology of globalization.Restores attention to poetic subgenres such as the ode and the prospect poem by offering a new, globalized interpretation of their ethical and political relevance.What happens when we think of poetry as a global literary form, while also thinking the global in poetic terms?F orms of a Worldshows how the innovations of contemporary poetics have been forged against a backdrop of globalization. Creatively intervening against the changes wrought by neoliberalism before they are made fully present, contemporary poets have remade the formal repertoire. In experimental reinventions of the ballad, the prospect poem, and the ode, Hunter excavates a new, globalized interpretation of the ethical and political relevance of forms.Shows how poetry exhorts us to imagine forms of social life and political intervention.

The mass rearing of animals in close quarters can be highly conducive to microbe transmission, including pathogens. This has been shown multiple times in the case of important industrial insects such as crickets, silkworms, and honeybees. One industrial insect of increasing importance is the black soldier fly (Diptera: Hermetia illucens), as it can convert organic waste into high-quality protein and fatty acids. Along with this, they take up far less space than traditional protein sources, as millions of black soldier flies can be reared in a relatively small facility. Because of this, there is a growing interest in the pathogens that could impact black soldier fly-rearing efforts. So far, only three black soldier fly-associated viruses have been identified. We used metatranscriptomic sequencing to survey black soldier fly guts, frass, and diet for viruses. We detected sequences from two novel viruses. One, which we name Hermetia illucens sigma-like virus 1, is phylogenetically related to viruses of the genus Sigmavirus, which have been highly studied in Drosophila. The other novel virus, which we name Hermetia illucens inse-like virus 1, is the second double-stranded RNA virus of the order Ghabrivirales described in the black soldier fly, and groups within a new family of insect viruses called the Inseviridae. We also detected two black soldier fly-associated viruses previously identified by our group: BSF nairo-like virus 1 and BSF uncharacterized bunyavirus-like 1. Consistent with our previous study, these two viruses are found primarily in frass samples and occur together more often than expected at random. When analyzing host transcription, we found significant differences in gene expression for eight candidate antiviral genes in the black soldier fly when comparing samples with and without viral sequences. Our results suggest that black soldier fly–virus interactions are ongoing, and they could be of interest to black soldier fly producers.

The study examined the association between body composition and beverage consumption and the risk of asthma and chronic obstructive pulmonary disease (COPD) and explored the single nucleotide polymorphisms (SNPs) involved in these associations by leveraging summary statistics from genome-wide association studies (GWAS) in nonoverlapping populations. The IEU OpenGWAS project was sourced for exposure datasets: body mass index, body fat percentage, fat-free mass, total body water mass, alcohol intake frequency, and coffee intake, and selected health outcome datasets: asthma and chronic obstructive pulmonary disease. Datasets were assessed and filtered using R, followed by a two-sample Mendelian randomization analysis. The MR Egger, weighted median, inverse variance weighted, simple mode, and weighted mode methods were used to examine the association between exposures and outcomes. Heterogeneity and pleiotropy analyses were used to evaluate the reliability of results. Additionally, SNPnexus was used to ascertain SNPs linked to established phenotypes, while SNP annotation was obtained from the Ensembl BioMart database via the biomaRt package. Genes belonging to overlapping groups were visualized using ComplexHeatmap. Higher body fat percentage (OR = 1.72, 95% CI: 1.23–2.41, p = 0.002), increased BMI (OR = 1.56, CI: 1.23–1.20, p = 2.53 × 10−4), and more frequent alcohol intake (OR = 1.34, CI: 1.08–1.68, p = 0.009) were associated with elevated COPD risk. Asthma risk was similarly increased with higher body fat percentage (OR = 1.60, CI: 1.23–2.21, p = 0.001), BMI (OR = 1.54, CI: 1.29–1.84, p = 2.23 × 10−6), fat-free mass (OR = 1.21, CI: 1.02–1.44, p = 0.032), and alcohol intake frequency (OR = 1.19, CI: 1.01–1.40, p = 0.039). Total body water mass and coffee intake were not associated with asthma and COPD. SNP annotation revealed that some genetic variants that influenced the association of the exposure variables with asthma and COPD were missense variants in several genes, including the evolutionarily highly conserved gene, SLC39A8 (rs13107325; C/A/T allele), and POC5 (rs2307111; T/A/C allele), as well as intronic variants in FTO (rs56094641; A/G/T allele) and NRXN3 (rs10146997; A/G allele). The discovery of the missense variants rs13107325 and rs2307111 in SLC39A8 and POC5, respectively, in addition to other intronic and synonymous SNPs suggests that these SNPs may have some roles in the development or progression of asthma and COPD. This may contribute to the identification of molecular signatures or biomarkers that forecast the risk, development, or therapeutic response of chronic lung diseases in persons with metabolic dysregulation, including obesity.

The composition of viral genomes, influenced by host-specific biases, offers insights into their evolutionary history. Vertebrate cells counter viral infection with interferons (IFNs) that activate IFN-stimulated genes, including the zinc-finger antiviral protein (ZAP), which binds CpG-rich single-stranded viral RNA (ssRNA). We trace the origin of ZAP along the vertebrate phylogeny and highlight its earlier emergence than previously described. Our analysis of ZAP orthologs shows that ZAP originated from a PARP12-like ancestor in the last common ancestor of tetrapods and lungfishes, more than 400 million years ago. Amphibian ZAP shares structural domains with its mammalian counterpart, though it typically lacks the C-terminal CAAX-box motif. The conserved RNA-binding domain in lungfish and tetrapod suggests an early functional reassignment. Subsequently, we found that CpG suppression in ssRNA viral genomes increases with the phylogenetic proximity of hosts to mammals, with amniote-infecting viruses showing the strongest bias, likely reflecting adaptation to ZAP-mediated immunity. These findings suggest that ZAP’s evolutionary steps include gene duplication in jawed vertebrates, structural adaptations in sarcopterygians, and membrane targeting capabilities in an early tetrapod, reflecting the complex coevolution of host antiviral defenses and viral evasion strategies.

The first full-length work to use prominent accounts of globalization to examine contemporary poetry written in English.Offers accessible readings of poetic form and of the contemporary political economy and sociology of globalization.Restores attention to poetic subgenres such as the ode and the prospect poem by offering a new, globalized interpretation of their ethical and political relevance.What happens when we think of poetry as a global literary form, while also thinking the global in poetic terms?F orms of a Worldshows how the innovations of contemporary poetics have been forged against a backdrop of globalization. Creatively intervening against the changes wrought by neoliberalism before they are made fully present, contemporary poets have remade the formal repertoire. In experimental reinventions of the ballad, the prospect poem, and the ode, Hunter excavates a new, globalized interpretation of the ethical and political relevance of forms.Shows how poetry exhorts us to imagine forms of social life and political intervention.

This essay follows the course of poetic exhortation through the contemporary work of two UK and U.S. poets whose lives are bound up in global processes: Sean Bonney and Myung Mi Kim. Exhortation is one of the modes, stances or registers of poetry that attempt to call forth a collective “we,” the “we” of lives that, in some case, lack a state at all or, in other cases, refuse to link their identities to an oppressive regime. Yet instead of making an explicit gesture toward including an existing group, these poets use a hortatory aesthetics to shape the formal totality of the poem. However different in the stances they assume, Bonney and Kim share a common endeavor to make the precarious “we” visible.

The mass rearing of animals in close quarters can be highly conducive to microbe transmission, including pathogens. This has been shown multiple times in the case of important industrial insects such as crickets, silkworms, and honeybees. One industrial insect of increasing importance is the black soldier fly (Diptera: Hermetia illucens), as it can convert organic waste into high-quality protein and fatty acids. Along with this, they take up far less space than traditional protein sources, as millions of black soldier flies can be reared in a relatively small facility. Because of this, there is a growing interest in the pathogens that could impact black soldier fly-rearing efforts. So far, only three black soldier fly-associated viruses have been identified. We used metatranscriptomic sequencing to survey black soldier fly guts, frass, and diet for viruses. We detected sequences from two novel viruses. One, which we name Hermetia illucens sigma-like virus 1, is phylogenetically related to viruses of the genus Sigmavirus, which have been highly studied in Drosophila. The other novel virus, which we name Hermetia illucens inse-like virus 1, is the second double-stranded RNA virus of the order Ghabrivirales described in the black soldier fly, and groups within a new family of insect viruses called the Inseviridae. We also detected two black soldier fly-associated viruses previously identified by our group: BSF nairo-like virus 1 and BSF uncharacterized bunyavirus-like 1. Consistent with our previous study, these two viruses are found primarily in frass samples and occur together more often than expected at random. When analyzing host transcription, we found significant differences in gene expression for eight candidate antiviral genes in the black soldier fly when comparing samples with and without viral sequences. Our results suggest that black soldier fly-virus interactions are ongoing, and they could be of interest to black soldier fly producers.The mass rearing of animals in close quarters can be highly conducive to microbe transmission, including pathogens. This has been shown multiple times in the case of important industrial insects such as crickets, silkworms, and honeybees. One industrial insect of increasing importance is the black soldier fly (Diptera: Hermetia illucens), as it can convert organic waste into high-quality protein and fatty acids. Along with this, they take up far less space than traditional protein sources, as millions of black soldier flies can be reared in a relatively small facility. Because of this, there is a growing interest in the pathogens that could impact black soldier fly-rearing efforts. So far, only three black soldier fly-associated viruses have been identified. We used metatranscriptomic sequencing to survey black soldier fly guts, frass, and diet for viruses. We detected sequences from two novel viruses. One, which we name Hermetia illucens sigma-like virus 1, is phylogenetically related to viruses of the genus Sigmavirus, which have been highly studied in Drosophila. The other novel virus, which we name Hermetia illucens inse-like virus 1, is the second double-stranded RNA virus of the order Ghabrivirales described in the black soldier fly, and groups within a new family of insect viruses called the Inseviridae. We also detected two black soldier fly-associated viruses previously identified by our group: BSF nairo-like virus 1 and BSF uncharacterized bunyavirus-like 1. Consistent with our previous study, these two viruses are found primarily in frass samples and occur together more often than expected at random. When analyzing host transcription, we found significant differences in gene expression for eight candidate antiviral genes in the black soldier fly when comparing samples with and without viral sequences. Our results suggest that black soldier fly-virus interactions are ongoing, and they could be of interest to black soldier fly producers.

The black soldier fly (Hermetia illucens, BSF) has emerged as an industrial insect of high promise because of its ability to convert organic waste into nutritious feedstock, making it an environmentally sustainable alternative protein source. As global interest rises, rearing efforts have also been upscaled, which is highly conducive to pathogen transmission. Viral epidemics have stifled mass-rearing efforts of other insects of economic importance, such as crickets, silkworms, and honeybees, but little is known about the viruses that associate with BSF. Although BSFs are thought to be unusually resistant to pathogens because of their expansive antimicrobial gene repertoire, surveillance techniques could be useful in identifying emerging pathogens and common BSF microbes. In this study, we used high-throughput sequencing data to survey BSF larvae and frass samples, and we identified two novel bunyavirus-like sequences. Our phylogenetic analysis grouped one in the family Nairoviridae and the other with two unclassified bunyaviruses. We describe these putative novel viruses as BSF Nairovirus-like 1 and BSF uncharacterized bunyavirus-like 1. We identified candidate segments for the full BSF Nairovirus-like 1 genome using a technique based on transcript co-occurrence and only a partial genome for BSF uncharacterized bunyavirus-like 1. These results emphasize the value of routine BSF colony surveillance and add to the number of viruses associated with BSF.

This book offers a manifesto for a radical existentialism aiming to regenerate the place of the outside that contemporary theory underestimates. Neyrat calls this outside \"atopia\": not utopia, a dreamt place out of the world where everything would be perfect, but atopia, the internal outside that is at the core of every being. Atopia is neither an object that an \"object-oriented ontology\" would be able to formalize, nor the matter that \"new materialisms\" could identify. Atopia is what constitutes the existence of any object or subject, its singularity or more precisely its \"eccentricity.\" Etymologically, to exist means \"to be outside\" and the book argues that every entity is outside, thrown in the world, wandering without any ontological anchor. In this regard, a radicalized existentialism does not privilege human beings (as Sartre and Heidegger did), but considers existence as a universal condition that concerns every being.It is important to offer a radical existentialism because the current denial of the outside is politically, and aesthetically, damaging. Only an atopian philosophy—a bizarre, extravagant, heretic philosophy—can care for our fear of the outside. For therapeutic element, a radical existentialism favors everything that challenges the compact immanence in which we are trapped, losing capacity to imagine political alternatives. To sustain these alternatives, the book identifies the atopia as a condition of the possibility to break immanence and analyze these breaks in human and animal subjectivity, language, politics and metaphysics.