Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
1,042
result(s) for
"Hutchinson, Michael"
Sort by:
Further : seeking the distant limits of cycling endurance
'Further' immerses the reader in the world of endurance cycling as well-known former professional cyclist Michael Hutchinson talks to ultra-distance athletes, exercise scientists, nutritionists and psychologists - 'those who've done it and those who understand it' - as he unpicks both the physical and mental demands, attempts to understand the key to successful endurance, and tries not to get himself accidentally killed while riding a frankly terrifyingly long-distance event.
BOOK
Climate Change and Range Expansion of the Asian Tiger Mosquito (Aedes albopictus) in Northeastern USA: Implications for Public Health Practitioners
The Asian tiger mosquito, Aedes albopictus (Skuse), is an invasive species with substantial biting activity, high disease vector potential, and a global distribution that continues to expand. New Jersey, southern New York, and Pennsylvania are currently the northernmost boundary of established Ae. albopictus populations in the eastern United States. Using positive geographic locations from these areas, we modeled the potential future range expansion of Ae. albopictus in northeastern USA under two climate change scenarios. The land area with environmental conditions suitable for Ae. albopictus populations is expected to increase from the current 5% to 16% in the next two decades and to 43%-49% by the end of the century. Presently, about one-third of the total human population of 55 million in northeastern USA reside in urban areas where Ae. albopictus is present. This number is predicted to double to about 60% by the end of the century, encompassing all major urban centers and placing over 30 million people under the threat of dense Ae. albopictus infestations. This mosquito species presents unique challenges to public health agencies and has already strained the resources available to mosquito control programs within its current range. As it continues to expand into areas with fewer resources and limited organized mosquito control, these challenges will be further exacerbated. Anticipating areas of potential establishment, while planning ahead and gathering sufficient resources will be the key for successful public health campaigns. A broad effort in community sanitation and education at all levels of government and the private sector will be required until new control techniques are developed that can be applied efficiently and effectively at reasonable cost to very large areas.
Journal Article
bioclim: the first species distribution modelling package, its early applications and relevance to most current MaxEnt studies
Aim Interest in species distribution models (SDMs) and related niche studies has increased dramatically in recent years, with several books and reviews being prepared since 2000. The earliest SDM studies are dealt with only briefly even in the books. Consequently, many researchers are unaware of when the first SDM software package (bioclim) was developed and how a broad range of applications using the package was explored within the first 8 years following its release. The purpose of this study is to clarify these early developments and initial applications, as well as to highlight bioclim's continuing relevance to current studies. Location Mainly Australia and New Zealand, but also some global applications. Methods We outline the development of the bioclim package, early applications (1984–1991) and its current relevance. Results bioclim was the first SDM package to be widely used. Early applications explored many of the possible uses of SDMs in conservation biogeography, such as quantifying the environmental niche of species, identifying areas where a species might be invasive, assisting conservation planning and assessing the likely impacts of climate change on species distributions. Main conclusions Understanding this pioneering work is worthwhile as bioclim was for many years one of the leading SDM packages and remains widely used. Climate interpolation methods developed for bioclim were used to create the WorldClim database, the most common source of climate data for SDM studies, and bioclim variables are used in about 76% of recent published MaxEnt analyses of terrestrial ecosystems. Also, some of the bioclim studies from the late 1980s, such as measuring niche (both realized and fundamental) and assessing possible impacts of climate change, are still highly relevant to key conservation biogeography issues.
Journal Article
How animals build
\"Get ready to explore the incredible world of animal architects! Lift the flaps and open gatefolds to discover amazing animal homes up high, underground, on land, and under the sea\"--Back cover.
Book
Rethinking aerobic exercise intensity prescription in adults with spinal cord injury: time to end the use of “moderate to vigorous” intensity?
Study designCohort study.ObjectivesTo investigate and critique different methods for aerobic exercise intensity prescription in adults with spinal cord injury (SCI).SettingUniversity laboratory in Loughborough, UK.MethodsTrained athletes were split into those with paraplegia (PARA; n = 47), tetraplegia (TETRA; n = 20) or alternate health condition (NON-SCI; n = 67). Participants completed a submaximal step test with 3 min stages, followed by graded exercise test to exhaustion. Handcycling, arm crank ergometry or wheelchair propulsion were performed depending on the sport of the participant. Oxygen uptake (V̇O2), heart rate (HR), blood lactate concentration ([BLa]) and ratings of perceived exertion (RPE) on Borg’s RPE scale were measured throughout. Lactate thresholds were identified according to log-V̇O2 plotted against log-[BLa] (LT1) and 1.5 mmol L−1 greater than LT1 (LT2). These were used to demarcate moderate (LT1, < LT2) and severe (>LT2) exercise intensity domains.ResultsAssociations between percentage of peak V̇O2 (%V̇O2peak) and HR (%HRpeak) with RPE differed between PARA and TETRA. At LT1 and LT2, %V̇O2peak and %HRpeak were significantly greater in TETRA compared to PARA and NON-SCI (P < 0.05). The variation in %V̇O2peak and %HRpeak at lactate thresholds resulted in large variability in the domain distribution at fixed %V̇O2peak and %HRpeak.ConclusionsFixed %V̇O2peak and %HRpeak should not be used for aerobic exercise intensity prescription in adults with SCI as the method does not lead to uniform exercise intensity domain distribution.
Journal Article
Elevation dependent spatial interpolation of hourly rainfall for accurate flood inundation modelling
High-quality rainfall data are crucial for various climatological and hydrological applications, especially in detailed modelling at fine temporal and spatial resolutions. However, obtaining precipitation data with fine spatiotemporal resolution is often challenging due to the limited availability of sub-daily point measurements and the sparse distribution of rainfall stations in many regions. This paper presents and demonstrates a method to generate the Commonwealth Scientific and Industrial Research Organisation Hourly Rainfall (CHRain) dataset, which provides hourly and 1 km gridded rainfall surfaces for hydrological/hydrodynamic modelling. The method applies thin-plate spline interpolation to generate rainfall surfaces using hourly input time series obtained from hourly rainfall stations, and from daily data disaggregated into hourly intervals based on patterns observed in nearby hourly rainfall stations, and also guided by continuous radar images. The method is used to represent rainfall patterns and amounts from 2007 to 2022 in the Richmond River catchment in New South Wales, Australia. Our analysis shows that the performance of the spline interpolation improves with the inclusion of the elevation data. Larger rainfalls responded more sensitively to changes in topography, with an optimum supporting DEM horizontal resolution of around 5 km, in agreement with previous studies. Performance was also significantly enhanced by using a stable spatial occurrence analysis to reliably remove false zeros from the data. About 0.26 % of the data were found to be false zeros. During the 2017 event, CHRain achieved a correlation coefficient of 0.949 against hourly gauges, showing that the dataset can adequately reproduce the patterns of hourly rainfall measurements. The spatial and temporal analyses indicate that the CHRain dataset outperforms other gridded datasets currently available in Australia in representing the sub-grid distribution, the daily and hourly variation of rainfall across the study area, and the high rainfall values. These are all essential for capturing the spatiotemporal characteristics of flood inundation in the study area, which is frequented by disastrous flood events.
Journal Article
Suicide and drought in New South Wales, Australia, 1970–2007
There is concern in Australia that droughts substantially increase the incidence of suicide in rural populations, particularly among male farmers and their families. We investigated this possibility for the state of New South Wales (NSW), Australia between 1970 and 2007, analyzing data on suicides with a previously established climatic drought index. Using a generalized additive model that controlled for season, region, and long-term suicide trends, we found an increased relative risk of suicide of 15% (95% confidence interval, 8%–22%) for rural males aged 30–49 y when the drought index rose from the first quartile to the third quartile. In contrast, the risk of suicide for rural females aged >30 y declined with increased values of the drought index. We also observed an increased risk of suicide in spring and early summer. In addition there was a smaller association during unusually warm months at any time of year. The spring suicide increase is well documented in nontropical locations, although its cause is unknown. The possible increased risk of suicide during drought in rural Australia warrants public health focus and concern, as does the annual, predictable increase seen each spring and early summer. Suicide is a complex phenomenon with many interacting social, environmental, and biological causal factors. The relationship between drought and suicide is best understood using a holistic framework. Climate change projections suggest increased frequency and severity of droughts in NSW, accompanied and exacerbated by rising temperatures. Elucidating the relationships between drought and mental health will help facilitate adaptation to climate change.
Journal Article
Potential Impacts of Climate Change on the Distribution of North American Trees
Currently predicted change in climate could strongly affect plant distributions during the next century. Here we determine the present-day climatic niches for 130 North American tree species. We then locate the climatic conditions of these niches on maps of predicted future climate, indicating where each species could potentially occur by the end of the century. A major unknown in this work is the extent to which populations of trees will actually track climate shifts through migration. We therefore present two extreme scenarios in which species either move entirely into future climatic niches or do not move out of their current niches. In the full-dispersal scenario, future potential ranges show decreases and increases in size, with an average decrease of 12% and a northward shift of 700 kilometers (km). In the no-dispersal scenario, potential ranges decrease in size by 58% and shift northward by 330 km. Major redistribution pressures appear to be in order under both dispersal scenarios.
Journal Article
Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis
In this trial involving patients with relapsing–remitting multiple sclerosis, BG-12 (dimethyl fumarate) reduced the annualized relapse rate and number of MRI lesions but not disability progression. BG-12 was associated with flushing, diarrhea, and decreased lymphocyte counts.
Multiple sclerosis is a chronic demyelinating and neurodegenerative disease of the central nervous system, which is commonly treated with parenteral agents (interferon beta and glatiramer acetate). Oxidative stress and proinflammatory stimuli are important pathologic factors in multiple sclerosis.
1
–
3
Experimental data suggest that BG-12, an oral formulation of dimethyl fumarate, has antiinflammatory and cytoprotective properties that are mediated through activation of the nuclear factor (erythroid-derived 2)–like 2 transcriptional pathway, among others.
3
–
6
Here, we report the results of the Comparator and an Oral Fumarate in Relapsing–Remitting Multiple Sclerosis (CONFIRM) trial, a randomized, multicenter, double-blind, 2-year study evaluating the efficacy and . . .
Journal Article