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Increased resolution has enabled kilometer‐scale weather and climate models to partially resolve secondary circulations, including horizontal convective rolls (HCRs) and cold pool gust fronts. Although these circulations are ubiquitous in convective boundary layers over land, their impacts on the surface energy balance are largely unknown. Doppler lidar and surface observations were combined with DOE E3SM land model experiments, revealing increased surface winds (5 m/s) and heat fluxes (50 W/m2) in convergent branches of HCRs. Larger wind‐driven flux responses (up to 150 W/m2) were found along gust fronts. Surface energy balance shifts to accommodate wind‐driven fluxes, reducing ground heat conduction and longwave cooling. Our findings from the US Southern Great Plains are broadly relevant to modeling convective boundary layers. In particular, widely used subgrid wind gust parameterizations were found to be physically inconsistent with resolved secondary circulations and could worsen climate prediction biases at kilometer‐scales. Plain Language Summary Earth's surface is heated by solar radiation, and this energy is transferred to the overlying air in the form of sensible and latent heat fluxes. Surface heat fluxes are generated by turbulent motions that are too small to be directly simulated in weather and climate models. Instead, models use mathematical functions, known as parameterizations, to predict surface fluxes from simulated winds and surface‐to‐air differences in moisture and temperature. Observed winds near Earth's surface are known to organize into patterns referred to as secondary circulations, creating frequently observed “cloud streets,” and influencing the soaring patterns of birds. With increasing computational power, weather, and climate models have begun to resolve these circulations in winds simulated at kilometer scales. Although they are widely observed, this study provides new evidence that secondary circulations significantly alter surface heat fluxes and the energy balance of the land surface. It is also shown that current parameterizations of wind‐driven heat fluxes can be made more realistic to improve predictions in weather and climate models that are run at kilometer‐scale spatial resolutions. Key Points Lidar and surface wind measurements provide evidence linking widely observed secondary circulations to surface wind gusts The circulations alter the land surface energy balance and increase surface heat fluxes in convergent branches of circulation updrafts Land model parameterizations are inconsistent with resolved circulations, pointing to needed improvements at kilometer‐scale resolutions

Clusteroluminogens refer to some non-conjugated molecules that show visible light and unique electronic properties with through-space interactions due to the formation of aggregates. Although mature and systematic theories of molecular photophysics have been developed to study conventional conjugated chromophores, it is still challenging to endow clusteroluminogens with designed photophysical properties by manipulating through-space interactions. Herein, three clusteroluminogens with non-conjugated donor-acceptor structures and different halide substituents are designed and synthesized. These compounds show multiple emissions and even single-molecule white-light emission in the crystalline state. The intensity ratio of these emissions is easily manipulated by changing the halide atom and excitation wavelength. Experimental and theoretical results successfully disclose the electronic nature of these multiple emissions: through-space conjugation for short-wavelength fluorescence, through-space charge transfer based on secondary through-space interactions for long-wavelength fluorescence, and room-temperature phosphorescence. The introduction of secondary through-space interactions to clusteroluminogens not only enriches their varieties of photophysical properties but also inspires the establishment of novel aggregate photophysics for clusteroluminescence. Although mature and systematic theories of molecular photophysics have been developed, it is still challenging to endow clusteroluminogens (CLgens) with designed photophysical properties by manipulating through-space interactions. Here, the authors design three CLgens that show multiple emissions and white-light emission in the crystalline state, and emphasize the important role of secondary through-space interactions between the acceptor and non-conjugated donor units.

The printing press had the potential to break the common lawyers' monopoly of legal knowledge. Early-modern England witnessed debates about the desirability of wider dissemination of legal learning. Previous scholarship has identified the long-term trend to increased printing of the law in English, focusing on ideological debates between lawyers and other key actors. Only selected texts and types of material were made available to the wider public before the 1620s. From the later 1620s a wider range of material which had hitherto existed only in manuscript was printed in English. Knowledge of the common law became more commonly available. This article identifies this crucial moment and explains the change. Rather than the ideological questions which are discussed in the existing literature, more mundane causes are identified for the legal profession's reduced control over the transmission of legal knowledge: a shift to the use of English by lawyers themselves, and a loss of professional control over manuscripts. The paper therefore demonstrates an important methodological point: understanding and assessing the history of legal printing requires engagement with older methods of transmitting the law.

Shiga toxin-producing Escherichia coli (STEC) cause substantial and costly illnesses. Leafy greens are the second most common source of foodborne STEC O157 outbreaks. We examined STEC outbreaks linked to leafy greens during 2009-2018 in the United States and Canada. We identified 40 outbreaks, 1,212 illnesses, 77 cases of hemolytic uremic syndrome, and 8 deaths. More outbreaks were linked to romaine lettuce (54%) than to any other type of leafy green. More outbreaks occurred in the fall (45%) and spring (28%) than in other seasons. Barriers in epidemiologic and traceback investigations complicated identification of the ultimate outbreak source. Research on the seasonality of leafy green outbreaks and vulnerability to STEC contamination and bacterial survival dynamics by leafy green type are warranted. Improvements in traceability of leafy greens are also needed. Federal and state health partners, researchers, the leafy green industry, and retailers can work together on interventions to reduce STEC contamination.

Rare Earth Elements (REE) are essential to modern society but the origins of many large REE deposits remain unclear. The U-Th-Pb ages, chemical compositions and C, O and Mg isotopic compositions of Bayan Obo, the world's largest REE deposit, indicate a protracted mineralisation history with unusual chemical and isotopic features. Coexisting calcite and dolomite are in O isotope disequilibrium; some calcitic carbonatite samples show highly varied δ 26 Mg which increases with increasing Si and Mg; and ankerite crystals show decreases in Fe and REE from rim to centre, with highly varied REE patterns. These and many other observations are consistent with an unusual mineralisation process not previously considered; protracted fluxing of calcitic carbonatite by subduction-released high-Si fluids during the closure of the Palaeo-Asian Ocean. The fluids leached Fe and Mg from the mantle wedge and scavenged REE, Nb and Th from carbonatite, forming the deposit through metasomatism of overlying sedimentary carbonate.

Tri-Butyl Tin (TBT) remains as a legacy pollutant in the benthic environments. Although the toxic impacts and endocrine disruption caused by TBT to gastropod molluscs have been established, the changes in energy reserves allocated to maintenance, growth, reproduction and survival of European oysters Ostrea edulis , a target species of concerted benthic habitat restoration projects, have not been explored. This study was designed to evaluate the effect of TBT chloride (TBTCl) on potential ions and relevant metabolomic pathways and its association with changes in physiological, biochemical and reproductive parameters in O . edulis exposed to environmental relevant concentrations of TBTCl. Oysters were exposed to TBTCl 20 ng/L (n = 30), 200 ng/L (n = 30) and 2000 ng/L (n = 30) for nine weeks. At the end of the exposure, gametogenic stage, sex, energy reserve content and metabolomic profiling analysis were conducted to elucidate the metabolic alterations that occur in individuals exposed to those compounds. Metabolite analysis showed significant changes in the digestive gland biochemistry in oysters exposed to TBTCl, decreasing tissue ATP concentrations through a combination of the disruption of the TCA cycle and other important molecular pathways involved in homeostasis, mitochondrial metabolism and antioxidant response. TBTCl exposure increased mortality and caused changes in the gametogenesis with cycle arrest in stages G0 and G1. Sex determination was affected by TBTCl exposure, increasing the proportion of oysters identified as males in O . edulis treated at 20ng/l TBTCl, and with an increased proportion of inactive stages in oysters treated with 2000 ng/l TBTCl. The presence and persistence of environmental pollutants, such as TBT, could represent an additional threat to the declining O . edulis populations and related taxa around the world, by increasing mortality, changing reproductive maturation, and disrupting metabolism. Our findings identify the need to consider additional factors (e.g. legacy pollution) when identifying coastal locations for shellfish restoration.

This article examines Tahar Ben Jelloun’s Mes Contes de Perrault (2014) as a multilayered instance of literary appropriation. Ben Jelloun’s stories, which relocate Charles Perrault’s classic French fairytales to the Arab world, represent not only a subversive challenge to French cultural hegemony (as has been argued) but can also be read as a complex engagement with the history of French folktales and their literary adaptations. This study posits that Ben Jelloun’s project restores elements of realism to Perrault’s tales that were lost when the author adapted folk stories for the French court. By reintroducing themes of bodily suffering, desire, and quotidian struggles, Ben Jelloun reconnects these tales with their folk origins. Examining Ben Jelloun’s “appropriation”—his word—in the context of Perrault’s own adaptations, this study offers new insights into the circulation and transformation of folktales across cultures and literary traditions. It contributes to ongoing discussions about literary and cultural appropriation and the place of the fairytale genre in today’s world.

The non-invasive estimation of blood oxygen saturation (SpO2) by pulse oximetry is of vital importance clinically, from the detection of sleep apnea to the recent ambulatory monitoring of hypoxemia in the delayed post-infective phase of COVID-19. In this proof of concept study, we set out to establish the feasibility of SpO2 measurement from the ear canal as a convenient site for long term monitoring, and perform a comprehensive comparison with the right index finger—the conventional clinical measurement site. During resting blood oxygen saturation estimation, we found a root mean square difference of 1.47% between the two measurement sites, with a mean difference of 0.23% higher SpO2 in the right ear canal. Using breath holds, we observe the known phenomena of time delay between central circulation and peripheral circulation with a mean delay between the ear and finger of 12.4 s across all subjects. Furthermore, we document the lower photoplethysmogram amplitude from the ear canal and suggest ways to mitigate this issue. In conjunction with the well-known robustness to temperature induced vasoconstriction, this makes conclusive evidence for in-ear SpO2 monitoring being both convenient and superior to conventional finger measurement for continuous non-intrusive monitoring in both clinical and everyday-life settings.

Among the growing number of works of graphic fiction, a number of titles dealing directly with the patient experience of illness or caring for others with an illness are to be found. Thanks in part to the Medical Humanities movement, many medical schools now encourage the reading of classic literature to gain insight into the human condition. Until recently, the medium of comics (the term is used in the plural to refer to both the physical objects and the attendant philosophy and practice surrounding them) has received little attention from healthcare scholars, even though some authors argue that graphic fiction is, in fact, a form of literature. This paper suggests that it is time that the medium was examined by healthcare professionals and studies some acclaimed comic works. Drawing on the principles of narrative medicine, this paper will ask whether comics and graphic novels could be used as a resource for health professionals, patients and carers.