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"Inglis, Tom"
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Meanings of life in contemporary Ireland : webs of significance
\"The struggle to create and sustain meaning in our everyday lives is fought using cultural ingredients to spin the webs of meaning that keep us going. To help reveal the complexity and intricacy of the webs of meaning in which they are suspended, Tom Inglis interviewed one-hundred people in their native home of Ireland to discover what was most important and meaningful for them in their lives. Inglis believes language is a medium: there is never an exact correspondence between what is said and what is felt and understood. Using a variety of theoretical lenses developed within sociology and anthropology, Inglis places their lives within the context of Ireland's social and cultural transformations, and of longer-term processes of change such as increased globalisation, individualisation, and informalisation\"-- Provided by publisher.
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Effect of Frailty on Outcome after Traumatic Spinal Cord Injury
Frailty negatively affects outcome in elective spine surgery populations. This study sought to determine the effect of frailty on patient outcome after traumatic spinal cord injury (tSCI).
Patients with tSCI were identified from our prospectively collected database from 2004 to 2016. We examined effect of patient age, admission Total Motor Score (TMS), and Modified Frailty Index (mFI) on adverse events (AEs), acute length of stay (LOS), in-hospital mortality, and discharge destination (home vs. other). Subgroup analysis (for three age groups: <60, 61–75, and 76+ years), and multi-variable analysis was performed to investigate the impact of age, TMS, and mFI on outcome.
For the 634 patients, the mean age was 50.3 years, 77% were male, and falls were the main cause of injury (46.5%). On bivariate analysis, mFI, age at injury, and TMS were predictors of AEs, acute LOS, and in-hospital mortality. After statistical adjustment, mFI was a predictor of LOS (p = 0.0375), but not of AEs (p = 0.1428) or in-hospital mortality (p = 0.1245).
In patients <60 years of age, mFI predicted number of AEs, acute LOS, and in-hospital mortality. In those aged 61–75, TMS predicted AEs, LOS, and mortality. In those 76+ years of age, mFI no longer predicted outcome.
Age, mFI, and TMS on admission are important determinants of outcome in patients with tSCI. mFI predicts outcomes in those <75 years of age only. The inter-relationship of advanced age and decreased physiological reserve is complex in acute tSCI, warranting further study. Identifying frailty in younger patients with tSCI may be useful for peri-operative optimization, risk stratification, and patient counseling.
Journal Article
Chicken Astrovirus (CAstV) Molecular Studies Reveal Evidence of Multiple Past Recombination Events in Sequences Originated from Clinical Samples of White Chick Syndrome (WCS) in Western Canada
In this study, we aimed to molecularly characterize 14 whole genome sequences of chicken astrovirus (CAstV) isolated from samples obtained from white chick syndrome (WCS) outbreaks in Western Canada during the period of 2014–2019. Genome sequence comparisons showed all these sequences correspond to the novel Biv group from which no confirmed representatives were published in GenBank. Molecular recombination analyses using recombination detection software (i.e., RDP5 and SimPlot) and phylogenetic analyses suggest multiple past recombination events in open reading frame (ORF)1a, ORF1b, and ORF2. Our findings suggest that recombination events and the accumulation of point mutations may have contributed to the substantial genetic variation observed in CAstV and evidenced by the current seven antigenic sub-clusters hitherto described. This is the first paper that describes recombination events in CAstV following analysis of complete CAstV sequences originated in Canada.
Journal Article
Molecular Characterization of Hemorrhagic Enteritis Virus (HEV) Obtained from Clinical Samples in Western Canada 2017–2018
Hemorrhagic enteritis virus (HEV) is an immunosuppressive adenovirus that causes an acute clinical disease characterized by hemorrhagic gastroenteritis in 4-week-old turkeys and older. Recurrent incidence of secondary infections (e.g., systemic bacterial infections, cellulitis, and elevated mortality), may be associated with the presence of field-type HEV in Canadian turkey farms. We speculate that field-type HEV and vaccine/vaccine-like strains can be differentiated through analysis of the viral genomes, hexon genes, and the specific virulence factors (e.g., ORF1, E3, and fib knob domain). Nine out of sixteen spleens obtained from cases suspected of immunosuppression by HEV were analyzed. The limited data obtained showed that: (1) field-type HEV circulates in many non-vaccinated western Canadian flocks; (2) field-type HEV circulates in vaccinated flocks with increased recurrent bacterial infections; and (3) the existence of novel point mutations in hexon, ORF1, E3, and specially fib knob domains. This is the first publication showing the circulation of wild-type HEV in HEV-vaccinated flocks in Western Canada, and the usefulness of a novel procedure that allows whole genome sequencing of HEV directly from spleens, without passaging in cell culture or passaging in vivo. Further studies focusing more samples are required to confirm our observations and investigate possible vaccination failure.
Journal Article
Sociological Forensics: Illuminating the Whole from the Particular
A central task in sociology is to make links between the micro world of events in everyday life and wider social structures and long-term processes of change. This is particularly evident in studying the impact of globalization on local cultural life. I argue that case studies are a good method for making connections between the micro and the macro. I use an example of a study of globalization I conducted in a village in Ireland. However, I also argue that within each case study there will be clues, episodes or events which, when analysed with the appropriate theories and concepts, will illuminate the micro and macro connections. This is what I mean by sociological forensics. I justify this approach by grounding it in sociological theory and pointing out how versions of it have been used in some classical case studies.
Journal Article
Rationing of hip and knee referrals in the public hospital : the true unmet need
Outlines the development of a triage system for elective hip and knee referrals to the Orthopaedic Department of the Canterbury District Health Board (CDHB). Determines the unmet need within this population for accessing first specialist assessment (FSA). Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence.
Journal Article
In-Hospital Mortality for the Elderly with Acute Traumatic Spinal Cord Injury
As the incidence of traumatic spinal cord injury (tSCI) in the elderly rises, clinicians are increasingly faced with difficult discussions regarding aggressiveness of management, likelihood of recovery, and survival. Our objective was to outline risk factors associated with in-hospital mortality in elderly surgical and non-surgical patients following tSCI and to determine those unlikely to have a favorable outcome. Data from elderly patients (≥ 65 years of age) in the Canadian Rick Hansen SCI Registry from 2004 to 2017 were analyzed using descriptive analysis. Survival and mortality groups in each of the surgical and non-surgical group were compared to explore factors associated with in-hospital mortality and their impact, using logistical regression. Of 1340 elderly patients, 1018 had surgical data with 826 having had surgery. In the surgical group, the median time to death post-injury was 30 days with 75% dying within 50 days compared with 7 days and 20 days, respectively, in the non-surgical group. Significant predictors for in-hospital mortality following surgery are age, comorbidities, neurological injury severity (American Spinal Injury Association [ASIA] Impairment Scale [AIS]), and ventilation status. The odds of dying 50 days post-surgery are six times higher for patients ≥77 years of age versus those 65–76 years of age, five times higher for those with AIS A versus those with AIS B/C/D, and seven times higher for those who are ventilator dependent. An expected probability of dying within 50 days post-surgery was determined using these results. In-hospital mortality in the elderly after tSCI is high. The trend with age and time to death and the significant predictors of mortality identified in this study can be used to inform clinical decision making and discussions with patients and their families.
Journal Article
Access to orthopaedic spinal specialists in the Canterbury public health system : quantifying the unmet need
Quantifies the unmet need for both spinal orthopaedic specialist assessment and, if warranted, surgical management of elective spine conditions within the Canterbury public health system. Highlights the degree of rationing within the public health system and its failure to adequately provide for the Canterbury public. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence.
Journal Article
Love and sex
Writers provide rich, thick descriptions of the cultures in which people live. They shine a light on the taken-for-granted ways of being, seeing and doing that cultural actors have developed over generations. Through fiction, novelists reveal the interests, feelings, moods and motivations of social actors. While social scientists have made it their business to try to understand how we interact, and while they often provide a description and explanation of the institutions, discourses and long-term processes of social change that structure culture, it is difficult for them to provide an understanding, similar to that of the novelist, of the intricate
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