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The liver plays a central role in regulating glucose and lipid metabolism. Aberrant insulin action in the liver is a major driver of selective insulin resistance, in which insulin fails to suppress glucose production but continues to activate lipogenesis in the liver, resulting in hyperglycemia and hypertriglyceridemia. The underlying mechanisms of selective insulin resistance are not fully understood. Here It is shown that hepatic membrane phospholipid composition controlled by lysophosphatidylcholine acyltransferase 3 (LPCAT3) regulates insulin signaling and systemic glucose and lipid metabolism. Hyperinsulinemia induced by high‐fat diet (HFD) feeding augments hepatic Lpcat3 expression and membrane unsaturation. Loss of Lpcat3 in the liver improves insulin resistance and blunts lipogenesis in both HFD‐fed and genetic ob/ob mouse models. Mechanistically, Lpcat3 deficiency directly facilitates insulin receptor endocytosis, signal transduction, and hepatic glucose production suppression and indirectly enhances fibroblast growth factor 21 (FGF21) secretion, energy expenditure, and glucose uptake in adipose tissue. These findings identify hepatic LPCAT3 and membrane phospholipid composition as a novel regulator of insulin sensitivity and provide insights into the pathogenesis of selective insulin resistance. Hepatic phospholipid (PL) saturation, mediated by depletion of a PL remodeling enzyme LPCAT3, protects mice from diet‐induced obesity through FGF21 and elevated energy expenditure. Ablation of Lpcat3 in the liver improves insulin sensitivity by facilitating insulin receptor endocytosis into early endosomes and glucose uptake in brown adipose tissue.

Converso and Morisco are the terms applied to those Jews and Muslims who converted to Christianity in large numbers and usually under duress in late Medieval Spain. The Converso and Morisco Studies publications will examine the implications of these mass conversions for the converts themselves, for their heirs (also referred to as Conversos and Moriscos) and for Medieval and Modern Spanish culture. As the essays in this collection attest, the study of the Converso and Morisco phenomena is not only important for those scholars focused on Spanish society and culture, but for academics everywhere interested in the issues of identity, Otherness, nationalism, religious intolerance and the challenges of modernity.Contributors include Mercedes Alcalá-Galan, Ruth Fine, Kevin Ingram, Yosef Kaplan, Sara T. Nalle, Juan Ignacio Pulido Serrano, Miguel Rodrigues Lourenço, Ashar Salah, Gretchen Starr-LeBeau, Claude Stuczynski, and Gerard Wiegers.

Converso and Morisco are the terms applied to those Jews and Muslims who converted to Christianity (mostly under duress) in late Medieval Spain. Converso and Moriscos Studies examines the manifold cultural implications of these mass convertions.

When the credit crisis started in 2007, the British press identified securitization as one of the main causes of banks woes and the financial crisis itself. Notwithstanding the criticism, securitization and securitization techniques are still widely used. Governments across the globe have recognized securitization and securitization techniques as necessary tools to be used in the short to medium term to stabilize the financial system and restart consumer and commercial lending. As a result, many of the government schemes put in place utilize securitization and securitization techniques. In conclusion, the article discusses the future role of securitization in the new post-credit crisis world.

Flood risk has increased in some parts of the world due to precipitation changes as well as sea-level rise, while wildfires have been more numerous as a result of extended droughts. The shareholder value of companies that had implemented all of our storm-protection recommendations prior to Hurricanes Harvey, Irma, and Maria outperformed those that hadn’t finished doing so by 10% in terms of shareholder value. [...]create an emergency response team that can develop sufficiently detailed emergency response plans and defined triggers to activate them.

As offices, plants and warehouses close to slow the spread of COVID-19, other risks are emerging at these now-idle facilities.

The best available evidence indicates that a serious fire would cost the company $220 million in property damage and lost revenue from business disruption. [...]you buy the requisite insurance coverage based on that projection. In addition to the $220 million in insured loss that a serious fire would cost, the model projected these uninsured losses: * Customer Loss: A protracted business disruption would prompt longtime customers to turn to other vendors, resulting in a projected loss in enterprise value of $200 million. * Lost growth: A major disruption would curtail the company’s growth at least over the short-to-medium term, and that lost growth is growth that it would never get back. Simply put, the total financial loss model takes a loss scenario and quantifies that risk in a completely different way, using a discounted cash-flow approach to calculate the loss in enterprise value that could occur as a result of reduced future cash streams and a related cost of capital increase.

According to The Institutes Risk & Insurance Knowledge Group, these two risk types constitute half of a CFO’s risk management job (the other half being strategic and financial risk). Risk managers should have data on maintenance, operating conditions, history, operators and other factors related to equipment like boilers, turbines, generators, transformers, chemical vessels, compressors, boilers, and pulp-and-paper processing machines. Kevin Ingram is executive vice president and chief financial officer of FM Global, one of the world’s largest commercial and industrial property insurers.