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Vermeer and the masters of genre painting : inspiration and rivalry
\"A landmark exploration of the engaging network of relationships among genre painters of the Dutch Golden Age The genre painting of the Dutch Golden Age between 1650 and 1675 ranks among the highest pinnacles of Western European art. The virtuosity of these works, as this book demonstrates, was achieved in part thanks to a vibrant artistic rivalry among numerous first-rate genre painters working in different cities across the Dutch Republic. They drew inspiration from each other's painting, and then tried to surpass each other in technical prowess and aesthetic appeal. The Delft master Johannes Vermeer (1632-1675) is now the most renowned of these painters of everyday life. Though he is frequently portrayed as an enigmatic figure who worked largely in isolation, the essays here reveal that Vermeer's subjects, compositions, and figure types in fact owe much to works by artists from other Dutch cities. Enlivened with 180 superb illustrations, Vermeer and the Masters of Genre Painting highlights the relationships - comparative and competitive - among Vermeer and his contemporaries, including Gerrit Dou, Gerard ter Borch, Jan Steen, Pieter de Hooch, Gabriel Metsu, and Frans van Mieris\"-- Provided by publisher.
Book
Linguistic gender congruity differentially correlates with film and novel ratings by critics and audiences
The film and publishing industries are fraught with gender disparities, with men overpowering nearly every sector of these domains. For instance, men are not only paid more than women in the film industry, but they also outnumber women in positions such as director, screenwriter, and lead acting roles. Similarly, women often resort to assuming gender-neutral or male pseudonyms to increase their prospects in the publishing industry. This widespread gender inequality in the film and publishing industries raises the question of how writers’ gender relates to gendered language and narrative receptions. Two archival studies examined whether gender-linked language relates to film ( N = 521) and novel ( N = 150) ratings, and whether those associations differ as a function of writer gender or the expertise of the rater (professional critics and lay audience members). Results demonstrated that female screenwriters and novelists used a more feminine style of writing, whereas male screenwriters and novelists used a more masculine style of writing. Lay audiences gave more positive ratings to films and novels by writers who used a more gender-congruent writing style, in contrast with professional critics, who gave more positive reviews to films by writers who used a more gender-incongruent writing style. Our findings substantiate past research regarding the differing tastes of lay audiences and professional critics in addition to lending insight into subtle social dynamics that may sustain gender biases in the film and publishing industries.
Journal Article
Feral youth
Follows ten teens who are left alone in the wilderness amid a three-day survival test.
Book
Language Style Matching Predicts Relationship Initiation and Stability
Previous relationship research has largely ignored the importance of similarity in how people talk with one another. Using natural language samples, we investigated whether similarity in dyads' use of function words, called language style matching (LSM), predicts outcomes for romantic relationships. In Study I, greater LSM in transcripts of 40 speed dates predicted increased likelihood of mutual romantic interest (odds ratio = 3.05). Overall, 33.3% of pairs with LSM above the median mutually desired future contact, compared with 9.1% of pairs with LSM at or below the median. In Study 2, LSM in 86 couples' instant messages positively predicted relationship stability at a 3-month follow-up (odds ratio = 1.95). Specifically, 76.7% of couples with LSM greater than the median were still dating at the follow-up, compared with 53.5% of couples with LSM at or below the median. LSM appears to reflect implicit interpersonal processes central to romantic relationships.
Journal Article
Can you catch Ebola from a stork bite? Inductive reasoning influences generalization of perceived zoonosis risk
Emerging zoonoses are a prominent global health threat. Human beliefs are central to drivers of emerging zoonoses, yet little is known about how people make inferences about risk in such scenarios. We present an inductive account of zoonosis risk perception, suggesting that beliefs about the range of animals able to transmit diseases to each other influence how people generalize risks to other animals and health behaviors. Consistent with our account, in Study 1, we find that participants who endorse higher likelihoods of cross-species disease transmission have stronger intentions to report animal bites. In Study 2, using real-world descriptions of Ebola virus from the WHO and CDC, we find that communications conveying a broader range of animals as susceptible to the virus increase intentions to report animal bites and decrease perceived safety of wild game meat. These results suggest that inductive reasoning principles may be harnessed to modulate zoonosis risk perception and combat emerging infectious diseases.
Journal Article
Surgical Outcomes and Associated Morbidity of Active and Expectant Management of Second-Trimester Placenta Accreta Spectrum (PAS)
Background and Objectives: Management of second-trimester placenta accreta spectrum (PAS) is currently center-dependent with minimal evidence-based practices. This study aims to analyze outcomes of hysterectomy as second-trimester active management (AM) versus cesarean hysterectomy as expectant management (EM) in cases of PAS with intraoperative and postoperative outcomes. Materials and Methods: This study is a retrospective case-control study of patients with a pathology-confirmed diagnosis of PAS managed at a single center over 16 years (2005–2020). All cases were diagnosed during the first or second trimester by ultrasonography and managed by the same multidisciplinary team with delivery within the second trimester. Results: Thirty-four patients with PAS were diagnosed and delivered by the second trimester. Of these, (41.1%) elected for active management and 20 (58.9%) for expectant management but ultimately required delivery prior to 28 weeks’ gestation. Baseline demographics were similar between groups. Intraoperatively, no differences were noted in operative time (191.5 vs. 203 min, p = 0.85), blood loss (2300 vs. 2600 cc, p = 0.85), or incidental cystotomy (1 vs. 7, p = 0.10). Postoperative length of stay was similar (3 vs. 3.5 days, p = 0.28), and ICU admission was not statistically different (6 vs. 12, p = 0.48). Conclusions: This retrospective study suggests that when hysterectomy is planned, there is no difference in maternal outcomes and morbidity with an expectant management with cesarean hysterectomy in the second trimester compared to proactive cesarean hysterectomy.
Journal Article
Association between Antenatal Vaginal Bleeding and Adverse Perinatal Outcomes in Placenta Accreta Spectrum
Background and Objectives: Placenta accreta spectrum (PAS) disorders are placental conditions associated with significant maternal morbidity and mortality. While antenatal vaginal bleeding in the setting of PAS is common, the implications of this on overall outcomes remain unknown. Our primary objective was to identify the implications of antenatal vaginal bleeding in the setting of suspected PAS on both maternal and fetal outcomes. Materials and Methods: We performed a case-control study of patients referred to our PAS center of excellence delivered by cesarean hysterectomy from 2012 to 2022. Subsequently, antenatal vaginal bleeding episodes were quantified, and components of maternal morbidity were assessed. A maternal composite of surgical morbidity was utilized, comprised of blood loss ≥ 2 L, transfusion ≥ 4 units of blood, intensive care unit (ICU) admission, and post-operative length of stay ≥ 4 days. Results: During the time period, 135 cases of confirmed PAS were managed by cesarean hysterectomy. A total of 61/135 (45.2%) had at least one episode of bleeding antenatally, and 36 (59%) of these had two or more bleeding episodes. Increasing episodes of antenatal vaginal bleeding were associated with emergent delivery (p < 0.01), delivery at an earlier gestational age (35 vs. 34 vs. 33 weeks, p < 0.01), and increased composite maternal morbidity (76, 84, and 94%, p = 0.03). Conclusions: Antenatal vaginal bleeding in the setting of PAS is associated with increased emergent deliveries, earlier gestational ages, and maternal composite morbidity. This important antenatal event may aid in not only counseling patients but also in the coordination of multidisciplinary teams caring for these complex patients.
Journal Article
Histopathological and Immunological Findings in the Common Marmoset Following Exposure to Aerosolized SARS-CoV-2
There is an enduring requirement to develop animal models of COVID-19 to assess the efficacy of vaccines and therapeutics that can be used to treat the disease in humans. In this study, six marmosets were exposed to a small particle aerosol (1–3 µm) of SARS-CoV-2 VIC01 that delivered the virus directly to the lower respiratory tract. Following the challenge, marmosets did not develop clinical signs, although a disruption to the normal diurnal temperature rhythm was observed in three out of six animals. Early weight loss and changes to respiratory pattern and activity were also observed, yet there was limited evidence of viral replication or lung pathology associated with infection. There was a robust innate immunological response to infection, which included an early increase in circulating neutrophils and monocytes and a reduction in the proportion of circulating T-cells. Expression of the ACE2 receptor in respiratory tissues was almost absent, but there was ubiquitous expression of TMPRSS2. The results of this study indicate that exposure of marmosets to high concentrations of aerosolised SARS-CoV-2 did not result in the development of clear, reproducible signs of COVID-19.
Journal Article
Development of a System to Deliver Inhalational Antibiotics to Marmosets
Background: Inhalational antibiotics have been used effectively to treat chronic diseases such as Pseudomonas aeruginosa infections associated with cystic fibrosis. This approach may enhance treatment options for difficult-to-treat, acute pneumonic diseases. Liposomal encapsulated ciprofloxacin (Lipoquin and/or Apulmiq) has provided protection in murine models of plague, anthrax, Q fever and tularemia. Development of the ability to deliver these drugs to nonhuman primates (NHPs) would enable further extrapolation of the data observed in small animal models of infection to humans. Methods: In this study, the methodology was established to deliver Apulmiq to common marmosets (Callithrix jacchus). Marmosets were anaesthetised with a novel, reversible anaesthetic comprising fentanyl, medetomidine and midazolam (FMM). They were placed into plethysmography tubes with their heads in an exposure chamber. The LC Sprint jet nebuliser or Pari eFlow Rapid nebuliser were used to aerosolise Apulmiq into the exposure chamber. Animals were euthanised after dosing and the concentration of ciprofloxacin was assessed in the plasma and lungs of the animals. Results: Non-compartmental pharmacokinetic analysis determined that a 30 min exposure of drug was required to reach a human-equivalent target dose of 0.8 mg/kg body weight in the lungs. Conclusions: This approach can now be used to assess the efficacy of inhalational liposomal ciprofloxacin in NHP infection models.
Journal Article