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7 result(s) for "Jacobs Foundation"
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Realizing the Potential of Immigrant Youth
The well-being and productivity of immigrant youth has become one of the most important global issues of our times as a result of mass migration and resettlement. In this unique volume, leading scholars from multiple nations and disciplines provide a state-of-the-art overview of contemporary research on immigrant youth and delineate the most promising future directions for research on their success, suggesting implications for policy and interventions that will benefit host societies as well as immigrant youth. The contributors to Realizing the Potential of Immigrant Youth include many of the leading international experts on migration, acculturation, intergroup issues and immigrant youth development, with contributions from the fields of child development, demography, economics, education, immigrant mental health, social psychology and sociology.
Joining Society
Joining Society asks precise questions: To what are the young socialized? Which skills, modes of thinking or action are required from them and what are their developmental value? Socialization tends to be viewed within the confines of a particular geographical or cultural situation. The multi-national list of contributors brings an international perspective to the problem of socialization to work and to adult life, while at the same time emphasizing the common issues that face youth around the world. Some of the topics addressed are the rules and roles involved in socialization, attaining personal agency through collective activity, use of new technologies, and the role of intergenerational relationships. This book sheds new light on the processes through which society may hope to intervene in positive ways with today's youth.
Youth in cities : a cross-national perspective
Using both comparative evidence and case studies, this volume illustrates the common needs of youth throughout the world, despite the highly varied socio-cultural circumstances in which they develop, and makes a case for the role of youth as creative social assets and positive forces for social change.
Proximity doesn't fix habits that undercut school success
In my book, \"Our School,\" I describe the struggles and triumphs of a charter high school in San Jose, Calif., that recruits 'D' and 'F' students, works their butts off and sends all graduates to college. Downtown College Prep succeeds because it targets instruction to struggling students who come from low-income and working-class families; most are the children of poorly educated Mexican immigrant parents. Mixing in middle-class whites would dilute the focus. That's been tried too with no effect on academic achievement. The journal Education Next reports on a study of families who moved out of public housing projects and into better neighborhoods in Boston, Baltimore, Chicago, Los Angeles and New York: \"A randomized evaluation of the 'Moving to Opportunity' program -- a federal housing program piloted in five major U.S. cities that sought to relocate poor families by providing housing vouchers -- shows that, contrary to expectations, moving families out of high-poverty neighborhoods has no overall positive impact on children's learning.\"
Nocardia infection in solid organ transplant recipients: A multicenter european case-control study
Background. Nocardiosis is a rare, life-threatening opportunistic infection, affecting 0.04% to 3.5% of patients after solid organ transplant (SOT). The aim of this study was to identify risk factors for Nocardia infection after SOT and to describe the presentation of nocardiosis in these patients.Methods. We performed a retrospective case-control study of adult patients diagnosed with nocardiosis after SOT between 2000 and 2014 in 36 European (France, Belgium, Switzerland, the Netherlands, Spain) centers. Two control subjects per case were matched by institution, transplant date, and transplanted organ. A multivariable analysis was performed using conditional logistic regression to identify risk factors for nocardiosis.Results. One hundred and seventeen cases of nocardiosis and 234 control patients were included. Nocardiosis occurred at a median of 17.5 (range, 2-244) months after transplant. In multivariable analysis, high calcineurin inhibitor trough levels in the month before diagnosis (odds ratio [OR], 6.11; 95% confidence interval [CI], 2.58-14.51), use of tacrolimus (OR, 2.65; 95% CI, 1.17-6.00) and corticosteroid dose (OR, 1.12; 95% CI, 1.03-1.22) at the time of diagnosis, patient age (OR, 1.04; 95% CI, 1.02-1.07), and length of stay in the intensive care unit after SOT (OR, 1.04; 95% CI, 1.00-1.09) were independently associated with development of nocardiosis; low-dose cotrimoxazole prophylaxis was not found to prevent nocardiosis. Nocardia farcinica was more frequently associated with brain, skin, and subcutaneous tissue infections than were other Nocardia species. Among the 30 cases with central nervous system nocardiosis, 13 (43.3%) had no neurological symptoms.Conclusions. We identified 5 risk factors for nocardiosis after SOT. Low-dose cotrimoxazole was not found to prevent Nocardia infection. These findings may help improve management of transplant recipients.
The genome of the water strider Gerris buenoi reveals expansions of gene repertoires associated with adaptations to life on the water
Background Having conquered water surfaces worldwide, the semi-aquatic bugs occupy ponds, streams, lakes, mangroves, and even open oceans. The diversity of this group has inspired a range of scientific studies from ecology and evolution to developmental genetics and hydrodynamics of fluid locomotion. However, the lack of a representative water strider genome hinders our ability to more thoroughly investigate the molecular mechanisms underlying the processes of adaptation and diversification within this group. Results Here we report the sequencing and manual annotation of the Gerris buenoi ( G. buenoi ) genome; the first water strider genome to be sequenced thus far. The size of the G. buenoi genome is approximately 1,000 Mb, and this sequencing effort has recovered 20,949 predicted protein-coding genes. Manual annotation uncovered a number of local (tandem and proximal) gene duplications and expansions of gene families known for their importance in a variety of processes associated with morphological and physiological adaptations to a water surface lifestyle. These expansions may affect key processes associated with growth, vision, desiccation resistance, detoxification, olfaction and epigenetic regulation. Strikingly, the G. buenoi genome contains three insulin receptors, suggesting key changes in the rewiring and function of the insulin pathway. Other genomic changes affecting with opsin genes may be associated with wavelength sensitivity shifts in opsins, which is likely to be key in facilitating specific adaptations in vision for diverse water habitats. Conclusions Our findings suggest that local gene duplications might have played an important role during the evolution of water striders. Along with these findings, the sequencing of the G. buenoi genome now provides us the opportunity to pursue exciting research opportunities to further understand the genomic underpinnings of traits associated with the extreme body plan and life history of water striders.