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Homeowners who prefer to build and live in forested areas should be aware of the dangers of forest fire and the steps which can be taken to prevent damage to their houses and even threats to their lives.

Our aim was to compare neuropsychological and psychiatric outcomes across three encephalitis aetiological groups: Herpes simplex virus (HSV), other infections or autoimmune causes (Other), and encephalitis of unknown cause (Unknown). Patients recruited from NHS hospitals underwent neuropsychological and psychiatric assessment in the short-term (4 months post-discharge), medium-term (9-12 months after the first assessment), and long-term (>1-year). Healthy control subjects were recruited from the general population and completed the same assessments. Patients with HSV were most severely impaired on anterograde and retrograde memory tasks. In the short-term, they also showed executive, IQ, and naming deficits, which resolved in the long-term. Patients with Other or Unknown causes of encephalitis showed moderate memory impairments, but no significant impairment on executive tests. Memory impairment was associated with hippocampal/medial temporal damage on magnetic resonance imaging (MRI), and naming impairment with left temporal and left frontal abnormalities. Patients reported more subjective cognitive complaints than healthy controls, with tiredness a significant problem, and there were high rates of depression and anxiety in the HSV and the Other encephalitis groups. These subjective, self-reported complaints, depression, and anxiety persisted even after objectively measured neuropsychological performance had improved. Neuropsychological and psychiatric outcomes after encephalitis vary according to aetiology. Memory and naming are severely affected in HSV, and less so in other forms. Neuropsychological functioning improves over time, particularly in those with more severe short-term impairments, but subjective cognitive complaints, depression, and anxiety persist, and should be addressed in rehabilitation programmes.

Between 1990 and 2000, the U.S. increased the number of Border Patrol Agents from 3,600 to 10,000. During that same period illegal immigration rose by 5.5. million. Moreover, over the past eight years, more than 2,000 men, women, and children have died attempting to cross into America and seek the opportunity to work and achieve a better life. The status quo is unacceptable and clinging to the status quo -- or tougher versions of it -- is neither conservative nor principled. It has become clear that the only viable approach to reform is combining enforcement with additional legal avenues for those who wish to work in our economy, while also addressing the situation of those already here in the U.S. Immigrants are crucial to our competitiveness and future labor and economic growth, as well as our military strength. Our country's welcoming attitude to immigrants will permit the U.S. to grow and prosper, as the populations of many other nations stagnate and decline. Each generation of Americans must connect our nation's past to its future and in so doing keep President [Reagan]'s vision of the \"Shining City\" alive.

Background Alzheimer's disease (AD) is the commonest cause of dementia. Cholinesterase inhibitors, such as donepezil, are the drug class with the best evidence of efficacy, licensed for mild to moderate AD, while the glutamate antagonist memantine has been widely prescribed, often in the later stages of AD. Memantine is licensed for moderate to severe dementia in AD but is not recommended by the England and Wales National Institute for Health and Clinical Excellence. However, there is little evidence to guide clinicians as to what to prescribe as AD advances; in particular, what to do as the condition progresses from moderate to severe. Options include continuing cholinesterase inhibitors irrespective of decline, adding memantine to cholinesterase inhibitors, or prescribing memantine instead of cholinesterase inhibitors. The aim of this trial is to establish the most effective drug option for people with AD who are progressing from moderate to severe dementia despite treatment with donepezil. Method DOMINO-AD is a pragmatic, 15 centre, double-blind, randomized, placebo controlled trial. Patients with AD, currently living at home, receiving donepezil 10 mg daily, and with Standardized Mini-Mental State Examination (SMMSE) scores between 5 and 13 are being recruited. Each is randomized to one of four treatment options: continuation of donepezil with memantine placebo added; switch to memantine with donepezil placebo added; donepezil and memantine together; or donepezil placebo with memantine placebo. 800 participants are being recruited and treatment continues for one year. Primary outcome measures are cognition (SMMSE) and activities of daily living (Bristol Activities of Daily Living Scale). Secondary outcomes are non-cognitive dementia symptoms (Neuropsychiatric Inventory), health related quality of life (EQ-5D and DEMQOL-proxy), carer burden (General Health Questionnaire-12), cost effectiveness (using Client Service Receipt Inventory) and institutionalization. These outcomes are assessed at baseline, 6, 18, 30 and 52 weeks. All participants will be subsequently followed for 3 years by telephone interview to record institutionalization. Discussion There is considerable debate about the clinical and cost effectiveness of anti-dementia drugs. DOMINO-AD seeks to provide clear evidence on the best treatment strategies for those managing patients at a particularly important clinical transition point. Trial registration Current controlled trials ISRCTN49545035

Mr. [Willy Brandt]'s vision is at once apocalyptic and utopian: dire predictions of widespread starvation and revolutionary upheaval alternate with rosy promises about the peace and prosperity that could presumably be achieved if only ''the North'' could muster the political will to help the poorer countries of ''the South.'' This makes for a dramatic but lofty argument that often seems to veer rather far from the concrete third world problems that Mr. Brandt proposes to address. Willy Brandt the crusader tends to get the better of Willy Brandt the pragmatic former Chancellor and architect of detente, and his tendentious political views - about multinational corporations, third world liberation movements, Unesco and the Eastern bloc's interest in development aid -often seem to undermine the value of his arguments.

OUTSIDE of South Africa, the journalist [Donald Woods] is best known as Steven Biko's friend: he introduced the black leader to foreign politicians, and after Biko's death in 1977 he fled the country in order to publish evidence that Biko was killed by South African police. But like most white South Africans, Mr. Woods did not come easily to radical politics or to friendship with a black man. As a student, he believed that blacks should be kept ''in their place'' on tribal reservations: he told classmates, ''it's either them or us.'' ''Asking for Trouble'' is a chatty, candid account of Mr. Woods's career: well-turned newspaperman's stories about golfing partners and newsroom colleagues as well as national figures. Historical events remain in the background, and Mr. Woods makes few full-throated pleas for any particular political program. He is most revealing and shrewd about the political deals he struck with the opposition in the interest of gradual change. Thus, for a time at least, he could overlook the long-range goal of Sports Minister Piet Koornhof, who wanted to abolish sports apartheid ''as a means of buying time for his government's general policies ... in order to prolong general apartheid.'' Mr. Woods carried the Minister's messages to exiled anti-apartheid groups; on several occasions he wrote Government press statements; at Mr. Koornhof's request, he helped suppress news of integrated sports that might have angered conservative whites. Mr. Woods's liberalism was practical rather than righteous, more wily than idealistic, and he was quite prepared to trick people into making changes he felt they would later appreciate.

It is becoming harder and harder for me to be hopeful these days of ever having peace in the Middle East. As an Arab-American and as a Lebanese who survived the siege of West Beirut in 1982, and who is lately witnessing the most one-sided, Zionist-biased media reporting ever, I am having a very hard time continuing to dream that one day Arabs and Israelis will be living in peace and harmony, side by side, each with dignity and true independence. That is, until I read [Bill Maxwell]'s article. I was appalled that the Journal-Constitution published the column by Bill Maxwell, who wants the United States to reconsider its ties to Israel and cut off all U.S. funding. Is Maxwell ignorant of the fact that Israel is the only democracy in the Middle East, and our only reliable ally there in the war against terrorism? He accuses Israel of being responsible for the violent conditions in the region. How many Israelis have strapped bombs to their bodies and then boarded buses or entered pizzerias filled with women and children? If he were really concerned about the misuse of U.S. foreign aid in the region, he would have noted that Egypt, the second- largest recipient of such aid, uses this money to teach hatred of the United States and Israel in its schools.

According to the EPA rule, Ash Grove could further reduce mercury emissions by installing \"dust-shuttling\" equipment.

According to the lawsuit, \"reinstatement is not feasible.\" In the 23-page lawsuit Brocato contends that as city manager he was a legally protected \"whistleblower\" and that the four councilors fired him in retaliation for his effort to show that Calder and Dorrah had conflicts of interest regarding changes the Council was considering making to the city's property maintenance ordinance.