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Carbon emissions, being hazardous, are triggering social concerns which have led to the creation of international treaties to address climate change. Similarly, the United Kingdom under the Climate Change Act (2008) has committed to reducing its greenhouse gas emission by at least 80% over 1990 levels by 2050. However, being the oldest member of the EU states (before Brexit), the UK has the oldest housing stock, which contributes to 45% of its carbon emissions due to the older dwellings. To address this issue low carbon retrofitting is needed. Therefore, this paper seeks to investigate the barriers and enablers to energy efficiency retrofitting in social housing in London, UK based on the perception of experts employed in National and construction companies with an experience that ranges between 6 to 16 years. Initial literature suggested that the problem of energy efficiency retrofitting in the general building stock has been addressed, however little has been reported on its application to social housing. This paper, therefore, groups the barriers and enablers into seven categories that include: financial matters, Technical, IT, Government policy and regulation, social factors (including awareness of the energy efficiency agenda), quality of workmanship and disruption to residents, using literature review, interviews and surveys with key stakeholders within the housing sector, and draws recommendations to enable effective and efficient retrofitting for social housing projects.

The mass transfer and hydrodynamic characteristics of a packed rotary contactor with a continuous liquid phase for the de-oxygenation of water using a stripping gas has been investigated. The primary purpose of this research was to gain a clearer understanding of the physical processes that occur within packings between the gas and liquid phases in an increased gravitational environment. The eventual aim is to design and develop a more efficient and cost effective industrial piece of equipment for the removal of dissolved oxygen from river or sea water. The mass transfer between two phases is directly related to the interfacial area which, in turn, is dependant on the gas bubble size. The use of centrifugal acceleration to generate increased gravitational environments leads to smaller bubbles being produced, with subsequent improvements in the mass transfer. In order to produce this increased gravitational environment, a one metre diameter rotor filled with a torus shaped packing was rotated between 200 and 400 rpm, with the gas phase dispersed in the liquid phase and passing through counter-currently. An examination of the overall gas and liquid flow through the packing in the rotor using visual and tracer techniques has been made which shows that the gas nozzle design and liquid flowrate are the two dominant parameters in achieving an effective and uniform distribution throughout. The gas bubble sizes produced have been visually analysed throughout the packing, and found to range from between 0.4 - 1.0 mm. in diameter. The mass transfer achieved in the rotor showed general trends of increasing with the gas flowrate and rotational speed, whilst falling as the liquid flowrate increased. For the entire range of rotor opemting conditions, the number of mass transfer units achieved was found to be in the range 1.5 - 4.5, and the corresponding height of a transfer unit between 4.5 - 12 cm.

Before the domain name becomes generally available, the Internet Content Management Registry has designated a \"sunrise period\", during which trademark owners can pay a one-off fee to \"reserve\" domain names containing their trademarks, so they cannot be registered under a \".xxx\" domain name for at least ten years.

Was it a good match? Cardiff started the better of the two sides, but Stephen Bywater was in fine form - he denied Robert Earnshaw's point-blank effort superbly. In the end, we had too much quality and deserved the three points. Who played well/who had a nightmare?

In the past two decades, three coronaviruses with ancestral origins in bats have emerged and caused widespread outbreaks in humans, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first SARS epidemic in 2002–2003, the appreciation of bats as key hosts of zoonotic coronaviruses has advanced rapidly. More than 4,000 coronavirus sequences from 14 bat families have been identified, yet the true diversity of bat coronaviruses is probably much greater. Given that bats are the likely evolutionary source for several human coronaviruses, including strains that cause mild upper respiratory tract disease, their role in historic and future pandemics requires ongoing investigation. We review and integrate information on bat–coronavirus interactions at the molecular, tissue, host and population levels. We identify critical gaps in knowledge of bat coronaviruses, which relate to spillover and pandemic risk, including the pathways to zoonotic spillover, the infection dynamics within bat reservoir hosts, the role of prior adaptation in intermediate hosts for zoonotic transmission and the viral genotypes or traits that predict zoonotic capacity and pandemic potential. Filling these knowledge gaps may help prevent the next pandemic.Bats harbour a multitude of coronaviruses and owing to their diversity and wide distribution are prime reservoir hosts of emerging viruses. Ruiz-Aravena, McKee and colleagues analyse the currently available information on bat coronaviruses and discuss their role in recent and potential future spillovers.

Isolated islands provide valuable opportunities to study the persistence of viruses in wildlife populations, including population size thresholds such as the critical community size. The straw-coloured fruit bat, Eidolon helvum, has been identified as a reservoir for henipaviruses (serological evidence) and Lagos bat virus (LBV; virus isolation and serological evidence) in continental Africa. Here, we sampled from a remote population of E. helvum annobonensis fruit bats on Annobón island in the Gulf of Guinea to investigate whether antibodies to these viruses also exist in this isolated subspecies. Henipavirus serological analyses (Luminex multiplexed binding and inhibition assays, virus neutralisation tests and western blots) and lyssavirus serological analyses (LBV: modified Fluorescent Antibody Virus Neutralisation test, LBV and Mokola virus: lentivirus pseudovirus neutralisation assay) were undertaken on 73 and 70 samples respectively. Given the isolation of fruit bats on Annobón and their lack of connectivity with other populations, it was expected that the population size on the island would be too small to allow persistence of viruses that are thought to cause acute and immunising infections. However, the presence of antibodies against henipaviruses was detected using the Luminex binding assay and confirmed using alternative assays. Neutralising antibodies to LBV were detected in one bat using both assays. We demonstrate clear evidence for exposure of multiple individuals to henipaviruses in this remote population of E. helvum annobonensis fruit bats on Annobón island. The situation is less clear for LBV. Seroprevalences to henipaviruses and LBV in Annobón are notably different to those in E. helvum in continental locations studied using the same sampling techniques and assays. Whilst cross-sectional serological studies in wildlife populations cannot provide details on viral dynamics within populations, valuable information on the presence or absence of viruses may be obtained and utilised for informing future studies.

Spatiotemporally-localised prediction of virus emergence from wildlife requires focused studies on the ecology and immunology of reservoir hosts in their native habitat. Reliable predictions from mathematical models remain difficult in most systems due to a dearth of appropriate empirical data. Our goal was to study the circulation and immune dynamics of zoonotic viruses in bat populations and investigate the effects of maternally-derived and acquired immunity on viral persistence. Using rare age-specific serological data from wild-caught Eidolon helvum fruit bats as a case study, we estimated viral transmission parameters for a stochastic infection model. We estimated mean durations of around 6 months for maternally-derived immunity to Lagos bat virus and African henipavirus, whereas acquired immunity was long-lasting (Lagos bat virus: mean 12 years, henipavirus: mean 4 years). In the presence of a seasonal birth pulse, the effect of maternally-derived immunity on virus persistence within modelled bat populations was highly dependent on transmission characteristics. To explain previous reports of viral persistence within small natural and captive E. helvum populations, we hypothesise that some bats must experience prolonged infectious periods or within-host latency. By further elucidating plausible mechanisms of virus persistence in bat populations, we contribute to guidance of future field studies.

Few studies have examined the genetic population structure of vector-borne microparasites in wildlife, making it unclear how much these systems can reveal about the movement of their associated hosts. This study examined the complex host–vector–microbe interactions in a system of bats, wingless ectoparasitic bat flies (Nycteribiidae), vector-borne microparasitic bacteria (Bartonella) and bacterial endosymbionts of flies (Enterobacterales) across an island chain in the Gulf of Guinea, West Africa. Limited population structure was found in bat flies and Enterobacterales symbionts compared to that of their hosts. Significant isolation by distance was observed in the dissimilarity of Bartonella communities detected in flies from sampled populations of Eidolon helvum bats. These patterns indicate that, while genetic dispersal of bats between islands is limited, some non-reproductive movements may lead to the dispersal of ectoparasites and associated microbes. This study deepens our knowledge of the phylogeography of African fruit bats, their ectoparasites and associated bacteria. The results presented could inform models of pathogen transmission in these bat populations and increase our theoretical understanding of community ecology in host–microbe systems.

Bats are reservoirs for emerging human pathogens, including Hendra and Nipah henipaviruses and Ebola and Marburg filoviruses. These viruses demonstrate predictable patterns in seasonality and age structure across multiple systems; previous work suggests that they may circulate in Madagascar's endemic fruit bats, which are widely consumed as human food. We aimed to (a) document the extent of henipa‐ and filovirus exposure among Malagasy fruit bats, (b) explore seasonality in seroprevalence and serostatus in these bat populations and (c) compare mechanistic hypotheses for possible transmission dynamics underlying these data. To this end, we amassed and analysed a unique dataset documenting longitudinal serological henipa‐ and filovirus dynamics in three Madagascar fruit bat species. We uncovered serological evidence of exposure to Hendra‐/Nipah‐related henipaviruses in Eidolon dupreanum, Pteropus rufus and Rousettus madagascariensis, to Cedar‐related henipaviruses in E. dupreanum and R. madagascariensis and to Ebola‐related filoviruses in P. rufus and R. madagascariensis. We demonstrated significant seasonality in population‐level seroprevalence and individual serostatus for multiple viruses across these species, linked to the female reproductive calendar. An age‐structured subset of the data highlighted evidence of waning maternal antibodies in neonates, increasing seroprevalence in young and decreasing seroprevalence late in life. Comparison of mechanistic epidemiological models fit to these data offered support for transmission hypotheses permitting waning antibodies but retained immunity in adult‐age bats. Our findings suggest that bats may seasonally modulate mechanisms of pathogen control, with consequences for population‐level transmission. Additionally, we narrow the field of candidate transmission hypotheses by which bats are presumed to host and transmit potentially zoonotic viruses globally. In this paper, the authors (a) expand globally on the known range of bat hosts for henipaviruses and filoviruses, (b) demonstrate seasonal patterns in population‐level seroprevalence and individual‐level serostatus for Malagasy fruit bats and (c) use mechanistic models to reveal the critical role of waning humoral immunity in serological dynamics.