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The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) ST398 among pigs in certain European countries and North America and its occurrence in other animal species raises a question concerning the molecular mechanisms mediating the success of this lineage. In this study a panel of S. aureus strains belonging to sequence type (ST) 5 (n = 4), ST8 (n = 5), ST15 (n = 5), ST22 (n = 8), clonal complex (CC) 30 (n = 8), CC97 (n = 8), CC130 (n = 4), CC151 (n = 4) and ST398 (n = 18) were screened by DNA microarray and PCR for the carriage of virulence and antimicrobial resistance genes. Isolates belonging to the same sequence type/clonal complex (ST/CC) were found to share similar virulence gene profiles. The ST398 lineage displayed the lowest content of virulence genes, which consisted mainly of genes detected among the majority or all of the analysed lineages. All MRSA ST398 isolates lacked accessory virulence genes that were detected in other ST/CC. In contrast to virulence genotype, the antimicrobial resistance genes profiles varied between isolates belonging to the same ST/CC and profile similarities could be observed for isolates from different lineages. MRSA ST398 isolates in particular displayed significant diversity and high content of antimicrobial resistance genes. This was comparable with certain MRSA belonging to other sequence types particularly the equine MRSA ST8. The apparent lack of significant virulence genes among MRSA ST398 strains, demonstrates that the lineage features a unique genetic background but no ST398-specific virulence markers could be identified.

The single-mirror small-size telescope (SST-1M) is one of the three proposed designs for the small-size telescopes (SSTs) of the Cherenkov Telescope Array (CTA) project. The SST-1M will be equipped with a 4 m-diameter segmented reflector dish and an innovative fully digital camera based on silicon photo-multipliers. Since the SST sub-array will consist of up to 70 telescopes, the challenge is not only to build telescopes with excellent performance, but also to design them so that their components can be commissioned, assembled and tested by industry. In this paper we review the basic steps that led to the design concepts for the SST-1M camera and the ongoing realization of the first prototype, with focus on the innovative solutions adopted for the photodetector plane and the readout and trigger parts of the camera. In addition, we report on results of laboratory measurements on real scale elements that validate the camera design and show that it is capable of matching the CTA requirements of operating up to high moonlight background conditions.

We present the analysis of the 93 ksec Chandra ACIS–S data for the galaxy CGCG 292–057 ( z = 0.054), with complex radio structure indicative of the intermittent jet activity. In order to characterize precisely the spectrum of the unresolved low-luminosity active nucleus in the source, we performed detailed MARX/PSF simulations and studied the radial profile of the source region surface brightness. In this way, we have detected an additional X-ray component extending from a few up to ∼10 kpc from the unresolved core, which could be associated with the hot gaseous medium compressed and heated (up to 0.9 keV) by the expanding inner lobes of the radio galaxy. We modeled the X-ray spectrum of the unresolved nucleus assuming various emission models, including an absorbed power-law, a power-law plus thermal emission component, and a two-temperature thermal plasma. The best fit was however obtained assuming a power-law emission scattered by a hot ionized gas, giving rise to the 6.7 keV iron line.

Chronic heart failure is a syndrome consisting in clinical symptoms that arise as a result of complications of many disease entities. According to the definition it is a condition in which, as a consequence of permanent heart dysfunction, cardiac output is reduced in relation to tissues’ metabolic demand. This results in subjective symptoms or proper cardiac output is sustained over higher filling pressure of the left heart ventricle. The occurrence of disease among adults in Europe and North America is 0.4-2%. Heart dysfunction detected by echocardiography appears with the frequency of 3%, and in people over 60 years of age it doubles with each decade of life, reaching 10% after 80 years of age. The aim of the study is to make an acquisition of fremitus in apex beat place and quantitative evaluation of some of their features which are correlated with the advanced syndrome. We have built the apparatus for the heart signal recording and proposed the original method of its analysis based on the theory of chaos and recurrence plots. It gave us, on the group of 85 patients, sensitivity equal to 0.896 specificity equal to 0.676 and the accuracy of diagnostics of the chronic heart failure equal up to 80%.

The Large Magellanic Cloud, a satellite galaxy of the Milky Way, has been observed with the High Energy Stereoscopic System (H.E.S.S.) above an energy of 100 billion electron volts for a deep exposure of 210 hours. Three sources of different types were detected: the pulsar wind nebula of the most energetic pulsar known, N 157B; the radio-loud supernova remnant N 132D; and the largest nonthermal x-ray shell, the superbubble 30 Dor C. The unique object SN 1987A is, unexpectedly, not detected, which constrains the theoretical framework of particle acceleration in very young supernova remnants. These detections reveal the most energetic tip of a γ-ray source population in an external galaxy and provide via 30 Dor C the unambiguous detection of γ-ray emission from a superbubble.

Relativistic and magnetized plasma ejected by radio loud AGNs through jets form the diffuse lobes of radio galaxies. The radiating particles (electron/electron–positron) in lobes emit in radio via the synchrotron process and X-ray via inverse-Compton scattering of cosmic microwave background photons. The thermal environment around radio galaxies emits X-rays via the thermal bremsstrahlung process. By combining information from these processes we can measure physical conditions in and around the radio lobes and thus study the dynamics of radio galaxies, including double–double radio galaxies.

J1159+5820 is an extended radio galaxy with a quite unusual morphology, featuring two pairs of radio lobes. Such sources, called double–double radio galaxies, constitute a very rare class of extragalactic radio sources. Furthermore, the extended radio structure of this source shows an X-shape form. According to a much likely scenario, such a morphology is due to interrupting nuclear activity in its central active galactic nucleus. Interestingly, the host of this source is a near-distance bright galaxy named CGCG 292-057, which is clearly disturbed, with tidal features and shells as plausible signs of a recent merger.

The ice caps that covered large parts of the continents of the northern hemisphere during the Pleistocene glaciations drained huge quantities of meltwater. In several places the erosive power of the meltwater rivers has led to the formation of ice-marginal valleys (IMVs). A much-debated question is whether sediments deposited in IMVs by proglacial and extraglacial streams can be distinguished on the basis of their heavy-mineral content. This question was assessed by an inventory of the heavy-mineral assemblages from the middle part of the Toruń-Eberswalde IMV in northwest Poland, two sandurs that supplied sediment from the north and the pre-Wisła river system that supplied sediment from the south; all these streams fed the IMV. The largely similar heavy-mineral compositions and sediments concentrations of the middle part of the IMV and sandurs suggest that the sediment in the IMV was supplied almost entirely by the streams on the sandurs but also that some sediments were eroded from the Miocene subsoil of the IMV itself and for a small part from the south by the pre-Wisła river system. The only heavy mineral in the pre-Wisła sediments for which the percentage is significantly different from those in the sediments of the sandurs and the IMV terrace is epidote. The difference, however, is not seen in the sediments of the IMV so it can be concluded that the sediment supply to the middle part of this IMV by streams from the south was insignificant. This is in contrast with what was hitherto commonly assumed.

The appearance of the jets and lobes of some radio galaxies makes it difficult to assign them to a known class of objects. This is often due to the activity of the central engine and/or interactions with the environment, as well as projection effects. We analyse the radio data for an apparently asymmetric radio source 4C70.19, which is associated with the giant elliptical galaxy NGC6048. The source shows distorted radio jets and lobes, one of which bends by 180 degrees. The aim of our study is to explain the nature of the observed distortions. We used LOFAR, Effelsberg, and VLA radio data in a wide range of frequencies. At high frequencies, we also used radio polarimetry to study the properties of the magnetic fields. Additionally, we made use of optical, infra-red, and X-ray data. Polarisation data suggest shearing of the magnetic fields at points where the jets bend. The low-frequency LOFAR map at 145 MHz, as well as the sensitive single-dish Effelsberg map at 8.35 GHz, reveal previously undetected diffuse emission around the source. The rotation measure (RM) derived from the polarimetric data allowed us to estimate the density of the medium surrounding the source, which agrees with typical densities of the intergalactic medium or the outer parts of insterstellar halos. We propose that the southern jet is bent in the same manner as the northern one, but that it is inclined to the sky plane. Both these bends are likely caused by the orbital motion within the galaxy group, as well as interactions with the intergalactic medium. Our analyses suggest that, despite its complex morphology, 4C70.19 seems to be intrinsically symmetric with a physical extent of up to 600 kpc, and that the diffuse emission detected in our high-sensitivity maps is related to radio plumes that are expanding behind the source.

The Pleistocene Cieśle succession accumulated in a subglacial tunnel and shows three sedimentological units: (1) trough cross-stratified sand with granules deposited in deep channels up to 5.4 m, (2) trough stratified and massive gravels deposited in a very deep channel up to 6.2 m eroded by a catastrophic hyperconcentrated flow, and (3) a massive diamicton, interpreted as a basal till of melt-out type. We focus on angular and deformed sandy clasts that occur in the second unit. It appears that thermal erosion, short transport in a sediment-laden current and sudden sedimentation were responsible for the oversized sandy clasts that occur in the gravel glaciofluvial deposits. The deposits are characterized by large-scale erosional scours, massive structure, and fluid-escape deformations. This combination of features can be used as a key tool for the interpretation of hyperconcentrated-flow conditions beneath Pleistocene ice sheets.