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Airborne transmission is the dominant route of coronavirus disease 2019 (COVID-19) transmission. The chances of contracting COVID-19 in a particular situation depend on the local demographic features, the type of inter-individual interactions, and the compliance with mitigation measures. In this work, we develop a multiscale framework to estimate the individual risk of infection with COVID-19 in different activity areas. The framework is parameterized to describe the motion characteristics of pedestrians in workplaces, schools, shopping centers and other public areas, which makes it suitable to study the risk of infection under specific scenarios. First, we show that exposure to individuals with peak viral loads increases the chances of infection by 99%. Our simulations suggest that the risk of contracting COVID-19 is especially high in workplaces and residential areas. Next, we determine the age groups that are most susceptible to infection in each location. Then, we show that if 50% of the population wears face masks, this will reduce the chances of infection by 8%, 32%, or 45%, depending on the type of the used mask. Finally, our simulations suggest that compliance with social distancing reduces the risk of infection by 19%. Our framework provides a tool that assesses the location-specific risk of infection and helps determine the most effective behavioral measures that protect vulnerable individuals.

Estimation of contact patterns is often based on questionnaires and time-use data. The results obtained using these methods have been used extensively over the years and recently to predict the spread of the COVID-19 pandemic. They have also been used to test the effectiveness of non-pharmaceutical measures such as social distance. The latter is integrated into epidemiological models by multiplying contact matrices by control functions. We present a novel method that allows the integration of social distancing and other scenarios such as panic. Our method is based on a modified social force model. The model is calibrated using data relating to the movements of individuals and their interactions such as desired walking velocities and interpersonal distances as well as demographic data. We used the framework to assess contact patterns in different social contexts in Morocco. The estimated matrices are extremely assortative and exhibit patterns similar to those observed in other studies including the POLYMOD project. Our findings suggest social distancing would reduce the numbers of contacts by 95%. Further, we estimated the effect of panic on contact patterns, which indicated an increase in the number of contacts of 11%. This approach could be an alternative to questionnaire-based methods in the study of non-pharmaceutical measures and other specific scenarios such as rush hours. It also provides a substitute for estimating children’s contact patterns which are typically assessed through parental proxy reporting in surveys.