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Flavanols, a common class of secondary plant metabolites, exhibit several beneficial health properties by acting as antioxidant, anticarcinogen, cardioprotective, anti-microbial, anti-viral, and neuroprotective agents. Furthermore, some flavanols are considered functional ingredients in dairy products. Based on their structural features and health-promoting functions, flavanols have gained the attention of pharmacologists and botanists worldwide. This review collects and summarizes 121 flavanols comprising four categories: flavan-3-ols, flavan-4-ols, isoflavan-4-ols, and flavan-3,4-ols. The research of the various structural features and pharmacological activities of flavanols and their derivatives aims to lay the groundwork for subsequent research and expect to provide mentality and inspiration for the research. The current study provides a starting point for further research and development.

Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang is a unique economic and medicinal plant of Cucurbitaceae in Southern China. For hundreds of years, Chinese people have used the fruit of S. grosvenorii as an excellent natural sweetener and traditional medicine for lung congestion, sore throat, and constipation. It is one of the first species in China to be classified as a medicinal food homology, which has received considerable attention as a natural product with high development potential. Various natural products, such as triterpenoids, flavonoids, amino acids, and lignans, have been released from this plant by previous phytochemical studies. Phar- macological research of the fruits of S. grosvenorii has attracted extensive attention, and an increasing number of extracts and compounds have been demonstrated to have antitussive, expectorant, antiasthmatic, antioxidant, hypoglycemic, immunologic, hepatoprotective, antibacte- rial, and other activities. In this review, based on a large number of previous studies, we summarized the related research progress of the chemical components and pharmacological effects of S. grosvenorii, which provides theoretical support for further investigation of its biological functions and potential clinical applications.

Plants from the Chrysanthemum genus are rich sources of chemical diversity and, in recent years, have been the focus of research on natural products chemistry. Sesquiterpenoids are one of the major classes of chemical constituents reported from this genus. To date, more than 135 sesquiterpenoids have been isolated and identified from the whole genus. These include 26 germacrane-type, 26 eudesmane-type, 64 guaianolide-type, 4 bisabolane-type, and 15 other-type sesquiterpenoids. Pharmacological studies have proven the biological potential of sesquiterpenoids isolated from Chrysanthemum species, reporting anti-inflammatory, antibacterial, antitumor, insecticidal, and antiviral activities for these interesting molecules. In this paper, we provide information on the chemistry and bioactivity of sesquiterpenoids obtained from the Chrysanthemum genus which could be used as the scientific basis for their future development and utilization.

The rapid urbanization process has gradually deepened its role in the sustainable development of agriculture, especially in the sustainable supply of food in poor areas, and has attracted more attention from international academic circles. However, the impact mechanism of different dimensions of urbanization on food sustainability in poor areas has not yet been fully unpacked. Therefore, this study focuses on potatoes as a specialty food mainly grown in poor areas of China, explores the impact mechanism of urbanization on the carbon emission intensity of potato production (CEIPP) with the spatial Durbin model, and compares with the carbon emission intensity of staple grain (CEISG) results. The main conclusions are as follows: the urbanization of main potato-producing areas developed rapidly from 2002 to 2020, which is in line with the decrease in CEIPP. The decrease in CEIPP has a significant impact on slowing down the growth of total carbon emissions and has greater potential for reduction, especially in Central and Western China, which has a large poverty-stricken population. Compared with traditional staple grain, urbanization has become a key factor influencing CEIPP. The results indicate that different dimensions of urbanization have varying degrees of impact on the sustainable production of regional specialty foods in China. The improvement of comprehensive urbanization, population urbanization, and economic urbanization reduces CEIPP, while land urbanization increases CEIPP. Therefore, to reduce CEIPP and promote its sustainable development, it is necessary to improve population urbanization and economic urbanization, properly avoid the disorderly expansion of land urbanization, and improve the quality and level of comprehensive urbanization.

Interdisciplinary research plays a crucial role in addressing complex problems by integrating knowledge from multiple disciplines. This integration fosters innovative solutions and enhances understanding across various fields. This study explores the historical and sociological development of interdisciplinary research and maps its evolution through three distinct phases: pre-disciplinary, disciplinary, and post-disciplinary. It identifies key internal dynamics, such as disciplinary diversification, reorganization, and innovation, as primary drivers of this evolution. Additionally, this study highlights how external factors, particularly the urgency of World War II and the subsequent political and economic changes, have accelerated its advancement. The rise of interdisciplinary research has significantly reshaped traditional educational paradigms, promoting its integration across different educational levels. However, the inherent contradictions within interdisciplinary research present cognitive, emotional, and institutional challenges for researchers. Meanwhile, finding a balance between the breadth and depth of knowledge remains a critical challenge in interdisciplinary education.

Heilaohu, the roots of Kadsura coccinea, has a long history of use in Tujia ethnomedicine for the treatment of rheumatoid arthritis and gastroenteric disorders, and a lot of work has been done in order to know the material basis of its pharmacological activities. The chemical investigation led to the isolation and characterization of three new (1–3) and twenty known (4–23) lignans. Three new heilaohulignans A-C (1–3) and seventeen known (4–20) lignans possessed dibenzocyclooctadiene skeletons. Similarly, one was a diarylbutane (21) and two were spirobenzofuranoid dibenzocyclooctadiene (22–23) lignans. Among the known compounds, 4–5, 7, 13–15 and 17–22 were isolated from this species for the first time. The structures were established, using IR, UV, MS and NMR data. The absolute configurations of the new compounds were determined by circular dichroism (CD) spectra. The isolated lignans were further evaluated for their cytotoxicity and antioxidant activities. Compound 3 demonstrated strong cytotoxic activity with an IC50 value of 9.92 µM, compounds 9 and 13 revealed weak cytotoxicity with IC50 values of 21.72 µM and 18.72 µM, respectively in the HepG-2 human liver cancer cell line. Compound 3 also showed weak cytotoxicity against the BGC-823 human gastric cancer cell line and the HCT-116 human colon cancer cell line with IC50 values of 16.75 µM and 16.59 µM, respectively. A chemiluminescence assay for antioxidant status of isolated compounds implied compounds 11 and 20, which showed weak activity with IC50 values of 25.56 µM and 21.20 µM, respectively.

As part of our continual efforts to exploit ‘Tujia Ethnomedicine’ for their pharmacophoric functionalities, we herein investigated Kadsura heteroclita collected from a deep Wulin mountain area in northern Hunan province. The current study resulted in the isolation of three new sesquiterpenes: 6α,9α,15-trihydroxycadinan-4-en-3-one (1), (+)-3,11,12-trihydroxycalamenene (2), (–)-3,10,11,12-tetrahydroxy-calamenene (3), along with four known sesquiterpenes (4–7), and a cytochalasin H (8). Their chemical structures were elucidated by 1D-, and 2D-NMR spectroscopy, and HRESI-MS, CD spectrometry. The antioxidant, and cytotoxic activities of the compounds were evaluated. Compound 8 exhibited a strong antioxidant effect with an IC50 value of 3.67 µM on isolated human polymorphonuclear cells or neutrophils.

The science-practice gap has recently been discussed as a critical challenge restricting sustainable growth and development in all facets of our society, including explorations of Recreation Ecosystem Services (RES). To better explore how well the scientific study of RES and its application are connected, this paper aims to synthesize empirical evidence based on an in-depth and systematic literature review. We found that studies of RES have not effectively transformed into the decision-making and long-term planning of our cities. From 2005 to 2020, only 13% of studies referred to specific applications, and about 40% of papers mentioned no applications or practical implications for their research. However, RES research has many potential applications, which can be categorised into six main aspects. In terms of non-spatial improvement: Improved monetary benefits (40%), non-monetary benefits (30%); in terms of spatial improvement: space with high recreational potential or degradation (7%), the relation between supply and demand (7%); and Cross-service governance (16%). After combining the results of various studies, we developed a framework starting from applicable problems and their solutions, which can incorporate the outcomes of RES research while systematically narrowing down the research questions and methods. The framework offers a starting point for further research that can modify and improve in bridging science-practice gaps in RES studies.

The use of spatio-temporal statistical combination method to explore the land use transition in urban suburbs provides an essential resource for promoting urban-rural integration and management of further urbanization. A combination of Space Time Cube and Geodetector methods was used to quantitatively identify the dominant morphology of land use change, and explore the recessive morphology and driving mechanism in Baiyun District, a suburb of Guangzhou from 1980 to 2020. Between these years, the land use changes were dominated by the expansion of built-up land and the shrinkage of cropland. The expansion took place in southern (1990-2000) to central (2000-2005) areas of the jurisdiction, followed by large-scale decentralization (2005-2010). Land use activities showed a downward trend. A continuous cold spot was mainly distributed in the southeast and remote areas near the urban center, whereas a continuous hot spot was spatially characterized by a multinuclear pattern, mainly concentrated in the center and south. Socioeconomic factors significantly affected the spatial pattern of land use activities. The trend turning in land use morphology of land use change can be divided into four stages: land primitivation from 1980 to 1990, land fragmentation from 1990 to 2000, land overflow from 2000 to 2010, and land intensification from 2010 to the present. Baiyun District is at the forefront of China’s development and has typical “suburban” characteristics, which can provide a reference for other suburbs in China to develop in stages. Today, urban suburbs in China face the problems of limited land resources and mixed land use space. Taking advantage of the new national strategic environment could effectively solve these land use issues in urban suburbs and achieve sustainable development. New trends in land use morphology research, also considering land use effects and land use change mechanisms in an integrated manner, are conducive to further deepening the understanding of land use transitions. Moreover, spatiotemporal statistical methods have innovated the field of mining the spatiotemporal characteristics of land use. Based on a scientific method for spatiotemporal analysis, we were able to reconstruct the three-dimensional space of land and improve the methods applied for research into land use change.

On the Android platform, information leakage can use an application-layer privilege escalation attack composed of multi-app collusion. However, the detection effect of a single app that can construct privilege escalation attacks is not good. Furthermore, the existing software and app measurement methods are not applicable to the measurement of collusion privilege escalation attacks. We propose a method for measuring the risk of a single app by using process algebra to model and determine the attack behavior, and we construct a measurement function based on sensitive data transitions and the feature set of attack behavior. Through the analysis of the privilege escalation attack model, the feature set of attack behavior is obtained. Then, based on the extracted behavior feature set, process algebra is used to model the dangerous behavior of an app. The dangerous behavior of the app is determined by weak equivalence and non-equivalence, and finally the risk of the app is measured based on the measurement function. Three known applications are used to verify the attack, and the risk measurement values are above 0.98. Based on the classification of applications on the market, we select typical apps in each category to build the test set. Benchmark tests and test set experiments show that the risk measurement results are consistent with the actual detection results, verifying the feasibility and effectiveness of this method.