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"Joma"
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Rapunzel = Rapunzel
A beautiful girl with extraordinarily long golden hair is imprisoned in a lonely tower by a witch.
Book
Global historical materialism and decoloniality
This debate piece offers a global historical materialist critique of decolonial theory, engaging Walter Mignolo’s work. It argues that decolonial literature, by creating abstract universals like modernity/coloniality, disarticulates theory from specific social formations and historical contexts. The author proposes eight methodological questions to demystify decolonial literature and reintegrate theory into history. Using Mignolo’s writings, the paper demonstrates how decolonial thinking can lead to political detachment and ineffective transformative strategies. The critique emphasises grounding theory in concrete social formations to render history legible and serve national liberation movements. By contrasting decolonial abstractions with historical examples from anti-colonial struggles on and beyond the African continent, it highlights decolonial thought’s limitations in addressing capitalism as a world system. It advocates for a global historical materialist analysis that integrates capitalism’s interconnected nature and reintroduces the social formation as a unit of analysis for understanding social relations.
Journal Article
Fault diagnosis and self-healing for smart manufacturing: a review
Manufacturing systems are becoming more sophisticated and expensive, particularly with the development of the intelligent industry. The complexity of the architecture and concept of Smart Manufacturing (SM) makes it vulnerable to several faults and failures that impact the entire behavior of the manufacturing system. It is crucial to find and detect any potential anomalies and faults as soon as possible because of the low tolerance for performance deterioration, productivity decline, and safety issues. To overcome these issues, a variety of approaches exist in the literature. However, the multitude of techniques make it difficult to choose the appropriate method in relation to a given context. This paper proposes a new architecture for a conceptual model of intelligent fault diagnosis and self-healing for smart manufacturing systems. Based on this architecture, a review method for the different approaches, sub-approaches and methods used to develop a Fault Detection and Diagnosis (FDD) and Self-Healing-Fault-Tolerant (SH-FT) strategy dedicated to smart manufacturing is defined. Moreover, this paper reviews and analyzes more than 256 scientific articles on fault diagnosis and self-healing approaches and their applications in SM in the last decade. Finally, promising research directions in the field of resilient smart manufacturing are highlighted.
Journal Article
Nanocarriers for natural polyphenol senotherapeutics
Senescence is a heterogenous and dynamic process in which various cell types undergo cell‐cycle arrest due to cellular stressors. While senescence has been implicated in aging and many human pathologies, therapeutic interventions remain inadequate due to the absence of a comprehensive set of biomarkers in a context‐dependent manner. Polyphenols have been investigated as senotherapeutics in both preclinical and clinical settings. However, their use is hindered by limited stability, toxicity, modest bioavailability, and often inadequate concentration at target sites. To address these limitations, nanocarriers such as polymer nanoparticles and lipid vesicles can be utilized to enhance the efficacy of senolytic polyphenols. Focusing on widely studied senolytic agents—specifically fisetin, quercetin, and resveratrol—we provide concise summaries of their physical and chemical properties, along with an overview of preclinical and clinical findings. We also highlight common signaling pathways and potential toxicities associated with these agents. Addressing challenges linked to nanocarriers, we present examples of senotherapeutic delivery to various cell types, both with and without nanocarriers. Finally, continued research and development of senolytic agents and nanocarriers are encouraged to reduce the undesirable effects of senescence on different cell types and organs. This review underscores the need for establishing reliable sets of senescence biomarkers that could assist in evaluating the effectiveness of current and future senotherapeutic candidates and nanocarriers. Cellular senescence is a critical concern in our aging population, and there is a growing need for strategies to modulate senescence. Polyphenols have been explored as senotherapeutics in preclinical and clinical settings. However, their application is hindered by limited stability, modest bioavailability, and insufficient concentrations at target sites. To overcome these limitations, nanocarriers including polymeric nanoparticles and lipid vesicles can be utilized to reduce cytotoxicity, enhance bioavailability, and augment the biological activity of several polyphenols.
Journal Article
Factors Influencing Teacher’s Technostress Experienced in Using Emerging Technology: A Qualitative Study
In this era of rapid technology growth, many countries have begun to adopt emerging technologies into their educational systems to improve learning outcomes. The aim of this study is to explore the factors influencing teachers’ experiences of technostress while using new technology in academic classrooms and how it might be mitigated. Prior research has not focused on how technostress develops among individuals over time or how it can be mitigated in an individual context; the intention of this study is to contribute to the technostress literature in these particular areas. To address the research gap, we conducted a qualitative study that collected data through the use of an open-ended question questionnaire. Seventy teachers of different backgrounds and locations responded to the survey. We used thematic analysis to analyze their responses and reveal how lack of school support and their professional identities influence their levels of technostress. Technology characteristics, including the complexity and the benefits of a given technology, and privacy concerns play a crucial role in teachers’ experiences of technostress. Moreover, we found that colleague support in using new technology and open educational resources each contributed to mitigating teachers’ technostress levels. Our study extends technostress research to examine a new learning environment and context. This focus allowed us to highlight the need to develop open educational resources and better social support structures for teachers and to rethink the professional identities of developing teachers to mitigate their levels of technostress. Suggestions for further research that resulted from this work include using a mixed methods research approach in future studies and including more teachers in future work to determine the relationships among the factors identified by this study.
Journal Article
The Impact of Strategic Agility on the Effectiveness of Decision-Making Process
The study aimed to explain the impact of strategic agility on the effectiveness of the decision-making process in Jordanian commercial banks. The study population consisted of employees work in Jordanian commercial banks. The study use questionnaire to collect data from respondents, out of 350 questionnaires were distributed 210 retrieved valid for analysis. The study employee SPSS to analyze data and test the hypotheses. The results indicated that there is a statistically significant impact of strategic agility dimensions (flexibility, speed, organizational capabilities) on the effectiveness of the decision-making process dimensions (identifying the problem, evaluating the situation, developing alternatives) at Jordanian commercial banks. The study recommended the decision makers in commercial banks to reallocate strategic resources in proportion to emergency changes, and the importance of effective cooperation and coordination between departments and branches.
Journal Article
Entrepreneurial e-equity crowdfunding platforms: antecedents of knowledge acquisition and innovation performance
PurposeThe crowdfunding concept and activities have recently been the focus of attention of many researchers and practitioners over different business contexts. However, there is a dearth of literature considering the main aspects of e-equity crowdfunding activities and their impact on the innovation performance for entrepreneurial business. Therefore, this study aims to explore how entrepreneurs' engagement in e-crowdfunding activities could enhance both knowledge acquisition and innovation performance.Design/methodology/approachThe conceptual model will be proposed based on three main theoretical perspectives: relationship marketing orientation (RMO); Kirzner's alertness theory; and the DeLone and McLean model of information systems. The data of the current study were collected using an online questionnaire from a sample of 500 entrepreneurs who have actively engaged in e-crowdfunding in Saudi Arabia.FindingsThe statistical results of structural equation modelling (SEM) approved the impacting role of RMO, entrepreneurial alertness, system quality and service quality on the entrepreneurs' engagement in e-equity crowdfunding, which in turn, predicts both knowledge acquisition and innovation performance.Research limitations/implicationsThere are several limitations which could be addressed in future studies, for example, this study has only considered one form of crowdfunding (equity based crowdfunding) and due to its nature these findings would not be easily generalized to other kinds of crowdfunding (i.e. donation-based crowdfunding; rewards-based crowdfunding; and debt-based crowdfunding). Future studies could consider these kinds of crowdfunding activities.Originality/valueThis study has contributed to the understanding of e-equity crowdfunding in several aspects. For example, this study presents results that assist both researchers and practitioners in the Middle East and Saudi Arabia to develop an in-depth knowledge of e-equity crowdfunding by considering new dimensions such as RMO and information system success factors.
Journal Article
Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates
During exposure to ionizing radiation, sub-lethal damage repair (SLDR) competes with DNA damage induction in cultured cells. By virtue of SLDR, cell survival increases with decrease of dose-rate, so-called dose-rate effects (DREs). Here, we focused on a wide dose-rate range and investigated the change of cell-cycle distribution during X-ray protracted exposure and dose-response curves via hybrid analysis with a combination of
in vitro
experiments and mathematical modelling. In the course of flow-cytometric cell-cycle analysis and clonogenic assays, we found the following responses in CHO-K1 cells: (1) The fraction of cells in S phase gradually increases during 6 h exposure at 3.0 Gy/h, which leads to radio-resistance. (2) Slight cell accumulation in S and G
2
/M phases is observed after exposure at 6.0 Gy/h for more than 10 hours. This suggests that an increase of SLDR rate for cells in S phase during irradiation may be a reproducible factor to describe changes in the dose-response curve at dose-rates of 3.0 and 6.0 Gy/h. By re-evaluating cell survival for various dose-rates of 0.186–60.0 Gy/h considering experimental-based DNA content and SLDR, it is suggested that the change of S phase fraction during irradiation modulates the dose-response curve and is possibly responsible for some inverse DREs.
Journal Article
Repercussions of the destruction of Gaza's sole psychiatric hospital
While the psychiatric hospital served as the primary institution, community mental health centres played a crucial role in providing psychological services, counselling and treatment to those unable to access hospital-based care. For many, suicide has become the only perceived escape from their unrelenting torment, a tragic reflection of the complete breakdown of mental health services. Prioritizing mental health services in conflict zones like Gaza is crucial for the wellbeing and future stability of its people. Prioritized interventions should include the deployment of mobile units to provide urgent psychiatric care and counselling for those unable to access other health centres; remote psychiatric consultations to extend mental health services, even with limited infrastructure; establishment of reliable supply chains for psychiatric medications to ensure consistent access for patients; training of local health professionals to handle mental health issues, filling the gaps left by the hospital's destruction; engagement of communities to reduce stigma, offer education and create support networks for patients and families; and research to gather data on the mental health impact of the conflict to inform targeted, evidence-based interventions.
Journal Article