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"Kay, Jeffrey"
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Over 90 % of children and adolescents return to sport after anterior cruciate ligament reconstruction: a systematic review and meta-analysis
by
Ayeni, Olufemi R.
,
Kay, Jeffrey
,
Peterson, Devin
in
Adolescent
,
Adolescents
,
Anterior cruciate ligament
2018
Purpose
To evaluate the rate at which children and adolescent athletes return to sporting activities after anterior cruciate ligament (ACL) reconstruction.
Methods
Three databases, PubMed, MEDLINE, and EMBASE, were searched from database inception until September 9, 2017 by two reviewers independently and in duplicate. The inclusion criteria were English language studies that reported return to sport outcomes. Book chapters, conference papers, review articles, and technical reports were excluded. The rate of return to sports was combined in a meta-analysis of proportions using a random-effects model.
Results
Overall, 20 studies with a combined total of 1156 ACL reconstructions met the inclusion criteria, with a mean age of 14.3 years (range 6–19) and a mean follow-up time of 6.5 years (range 1–22). All studies were level IV evidence (14 retrospective case series and 6 prospective case series). The pooled rate of return to any sport participation was 92.0% [95% confidence interval (CI), 86–96%]. The pooled rate of return to pre-injury level of sport was 78.6% (95% CI 71–86%) and that to competitive level of sport was 81.0% (95% CI 62–94%). A total of 93 of the 717 assessed athletes (13%) sustained re-injuries with graft ruptures, and in 91 of 652 patients (14%), contralateral ACL injuries were reported on final follow-up.
Conclusion
Pooled results suggest a high rate of return to sport following ACL reconstruction in children and adolescent athletes; however, this is associated with a relatively high rate of graft rupture and a similar rate of contralateral ACL injury. This study provides clinicians with evidence-based data on the ability of children and adolescent athletes to return to sport after ACL reconstruction, an important consideration for athletes of this population with ACL injuries.
Level of evidence
IV, systematic review of level IV studies.
Journal Article
Anatomical double-bundle anterior cruciate ligament reconstruction moderately improved tegner scores over the long-term: a systematic review and meta-analysis of randomized controlled trials
by
Yousif, Eliya
,
Jeffrey, Kay
,
Kanto, Nagai
in
Adult
,
Anatomical Anterior cruciate ligament reconstruction (ACLR)
,
Anterior cruciate ligament
2023
Purpose
To assess the effects of anatomical double-bundle (DB) versus single-bundle (SB) for anterior cruciate ligament (ACL) reconstruction in skeletally mature patients with ACL injuries.
Methods
MEDLINE, EMBASE, and CENTRAL were searched from inception to February 7, 2022 were screened for randomized controlled trials. The Anatomic Anterior Cruciate Ligament Reconstruction Checklist was used to categorize studies as anatomic. A random-effects meta-analysis was conducted, with pooled results being summarized using mean difference (MD). Risk of Bias (RoB) was assessed using the RoB 2.0 tool. Certainty of evidence was rated using GRADE.
Results
A search of 1371 unique articles yielded eight eligible trials, representing 735 patients (360 DB, 375 SB) with mean (SD) age of 28.5 (2.86) years and follow-up of 52.1 (36.2) months. Most trials had moderate to low RoB. Overall, DB was not significantly better than SB on Lysholm scores (MD = 0.52, 95% CI, − 1.80–2.85,
p
= 0.66; moderate certainty) or subjective International Knee Documentation Committee (IKDC) scores (MD = − 0.40, 95% CI, − 4.35–3.55,
p
= 0.84; moderate certainty). Tegner scores were significantly higher in SB than DB in the intermediate term (MD = − 0.72, 95% CI, − 1.10 to − 0.34,
p
= 0.0002; high certainty), while significantly higher in DB relative to SB in the long-term (MD = 0.52, 95% CI, 0.02–1.03,
p
= 0.04; high certainty).
Conclusion
DB ACL reconstruction significantly improves Tegner scores relative to SB ACL reconstruction over the long-term (
t
≥ 5 years). Intermediate term Tegner scores favour SB reconstruction. In both durations, there was no clinically significant difference based on the pre-specified minimal clinically important difference of 1.0 point. There were also no significant differences in IKDC or Lysholm scores. Surgeons should consider anatomical DB ACL reconstruction as a result of long-term improvement in patient-reported outcomes.
Level of evidence
I.
Journal Article
Quadriceps tendon autograft for pediatric anterior cruciate ligament reconstruction results in promising postoperative function and rates of return to sports: A systematic review
by
Zakharia, Alexander
,
Kay, Jeffrey
,
Hoshino, Yuichi
in
Adolescent
,
Anterior cruciate ligament
,
Anterior Cruciate Ligament Injuries - etiology
2022
Purpose
To assess the performance of the quadriceps tendon (QT) autograft in pediatric anterior cruciate ligament reconstruction (ACLR).
Methods
A systematic search of MEDLINE, PubMed, and EMBASE was conducted on March 1, 2021. Studies of all levels of evidence reporting outcomes and/or complications after QT autograft ACLR in pediatric patients (≤ 18 years old) were eligible for inclusion. Study demographics, patient demographics, reported outcomes, and complications were abstracted. Screening and data abstraction were designed in accordance with PRISMA and R-AMSTAR guidelines. Descriptive statistics were presented when applicable, with data for heterogeneous outcomes presented in narrative summary fashion.
Results
A total of 14 studies examining 596 patients (46.3% female), mean age 15.4 years, were included in this systematic review. Mean postoperative Lysholm scores ranged from 94.0 to 99.5. Mean postoperative IKDC subjective scores ranged from 75.9 to 94.0. Limb symmetry index ranged from 96.8 ± 10.4 to 100.4 ± 7.6% across multiple hop tests. Return to sports (RTS) rates ranged from 88.9 to 91.7%. Eleven studies reported postoperative complications, whereby 16 patients (4.8%) experienced contralateral complications and injuries. Forty-six patients (9.4%) experienced ipsilateral complications, including ten graft failures (2.5%) and two growth disturbances (0.6%).
Conclusions
QT autograft ACLR in the pediatric population retains the potential of regaining a preinjury level of knee stability, and yields promising postoperative function and rates of RTS, yielding comparable outcomes relative to HT autograft and the reference-standard BPTB ACLR that have previously been described in the literature. Moreover, use of the QT autograft is associated with low rates of postoperative complications, including graft failure and growth disturbances in this active and high-risk patient population in observational studies to date. Therefore, clinical equipoise exists to further appraise the influence of QT autograft on postoperative outcomes compared to aforementioned autograft options in a randomized control trial fashion.
Level of evidence
IV.
Journal Article
Predictors of Outcomes After Hip Arthroscopic Surgery for Femoroacetabular Impingement: A Systematic Review
by
Ayeni, Olufemi R.
,
Kay, Jeffrey
,
Sogbein, Olawale A.
in
Body mass index
,
Orthopedics
,
Sports medicine
2019
Background:
The benefits of hip arthroscopic surgery in the setting of femoroacetabular impingement (FAI) have been well established; however, some patients may experience a greater degree of improvement than others. Identifying positive and negative predictors of outcomes would assist the orthopaedic surgeon’s management algorithm for patients with FAI.
Purpose/Hypothesis:
The objective of this systematic review was to identify demographic, radiographic, and other operative predictors of positive and negative outcomes after hip arthroscopic surgery for patients with FAI. It was hypothesized that factors including FAI morphology, age, body mass index (BMI), sex, dysplasia, articular cartilage damage, radiographic joint space, and labral treatment would predict outcomes after hip arthroscopic surgery.
Study Design:
Systematic review; Level of evidence, 4.
Methods:
This systematic review was performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Three databases (Embase, PubMed, and Ovid [MEDLINE]) were searched on May 19, 2018, using terms including “hip,” “arthroscopy,” and “FAI.” Studies were screened and data extracted in duplicate.
Results:
A total of 39 studies were included in this systematic review, comprising 9272 hips with a mean age of 36.5 years (47.2% female). Younger age, male sex, lower BMI (<24.5 kg/m2), Tönnis grade 0, and preoperative pain relief from diagnostic intra-articular hip injections predicted positive outcomes. Female sex, older age (>45 years), longer duration of preoperative symptoms (>8 months), elevated BMI, increased Tönnis grade (≥1), chondral defects, decreased joint space (≤2 mm), increased Kellgren-Lawrence grade (>3), increased lateral center-edge angle (LCEA), and undergoing labral debridement alone were predictors of negative outcomes.
Conclusion:
In patients with FAI, younger age, male sex, lower BMI (<24.5 kg/m2), Tönnis grade 0, and pain relief from preoperative intra-articular hip injections are significantly more likely to achieve positive outcomes after hip arthroscopic surgery. On the other hand, older age (>45 years), female sex, elevated BMI, osteoarthritic changes, decreased joint space (≤2 mm), chondral defects, increased LCEA, and undergoing labral debridement compared with labral repair are associated with negative outcomes.
Journal Article
Assessment of Return to Sport After ACL Reconstruction With Soft Tissue Autograft in Adolescent Athletes: Quadriceps Versus Hamstring Tendon
by
Kay, Jeffrey
,
Liotta, Elizabeth S.
,
Heyworth, Benton E.
in
Athletic performance
,
Orthopedics
,
Sports medicine
2023
Background:
Quadriceps tendon soft tissue autograft represents an increasingly popular graft option for anterior cruciate ligament reconstruction (ACLR), particularly for adolescents, some of whom have an open physis, precluding use of graft options with bone plugs.
Purpose/Hypothesis:
The purpose of this study was to quantify return-to-sport performance assessments in adolescents at 6 months after ACLR with all–soft tissue quadriceps tendon autograft (ACLR-Q) versus hamstring tendon autograft (ACLR-HS). It was hypothesized that ACLR-Q would be associated with improved hamstring strength and hamstring-to-quadriceps (HS:Q) ratios compared with ACLR-HS, albeit with decreased quadriceps strength.
Study Design:
Cross-sectional study; Level of evidence, 3.
Methods:
Included were patients aged 12 to 19 years who underwent primary ACLR by a single surgeon and who completed a return-to-sport performance assessment between 5 and 9 months postoperatively. The performance assessment included manual muscle strength tests (hamstring, quadriceps, hip abductor and adductor), dynamic balance test (Y-balance), and functional hop tests (single hop, triple hop, crossover hop, 6-m timed hop). Data were converted to limb symmetry indices, and limb symmetry index deficits were compared between the ACLR-Q and ACLR-HS cohorts using the Student t test or Wilcoxon-Mann-Whitney test.
Results:
An initial cohort of 90 ACLR-Q patients was compared with 54 ACLR-HS patients, with no significant differences in patient characteristics. Differences in meniscal repair rates, however, prompted use of propensity score matching on age, sex, body mass index, meniscectomy, and meniscal repair to produce comparable subcohorts. The matching resulted in 67 ACLR-Q and 52 ACLR-HS patients. Hamstring strength deficits were significantly greater in ACLR-HS versus ACLR-Q patients (−40.5% vs −5.7%; P < .001). Quadriceps strength deficits were significantly greater in ACLR-Q versus ACLR-HS patients (−12.8% vs −0.4%; P < .001). ACLR-Q patients had a significantly greater HS:Q ratio on the operative knee (P < .001) and significantly higher Y-balance composite score deficits (−2.9% vs −0.4%; P = .01) than ACLR-HS patients. There were no significant differences in hop test performance between groups.
Conclusion:
Adolescent athletes who underwent ACLR-Q showed significantly greater quadriceps strength deficits but significantly smaller hamstring strength deficits than those who underwent ACLR-HS, leading to more favorable HS:Q ratios in ACLR-Q patients at 6 months postoperatively.
Journal Article
Correction to: Clinical and radiographic predictors of failed hip arthroscopy in the management of dysplasia: a systematic review and proposal for classification
by
Olufemi R. Ayeni
,
Muzammil Memon
,
Jeffrey Kay
in
Correction
,
Medicine
,
Medicine & Public Health
2020
Unfortunately, the author name was incorrectly published in the original publication as Sochi Uchida insted of Soshi Uchida. The author name is corrected here by this Erratum. The original article has been corrected.
Journal Article
Paper 08: Arthroscopic Bankart Repair for Anterior Glenohumeral Instability in Adolescent Athletes: Risk Factors for Subsequent Revision Stabilization
2024
Objectives:
Adolescent athletes with a primary anterior glenohumeral dislocations have been shown to have a relatively high incidence of recurrent instability. Evolving evidence on this topic has led to increasing rates of arthroscopic stabilization over the last 2 decades. However, the timing and role of surgery following a single dislocation episode is one of the most controversial topics in orthopaedics. While arthroscopic stabilization is effective in allowing return to play, adolescents have higher rates of subsequent recurrent instability than any other age group. Identifying patients at highest risk of such events postoperatively may facilitate optimized surgical decision-making in this population. The purpose of this study was to identify prognostic factors that are associated with recurrent instability requiring reoperation following arthroscopic Bankart repair in adolescents, with particular attention to the number of dislocations sustained prior to the index procedure.
Methods:
All patients 12 to 21 years old who had undergone arthroscopic Bankart repair surgery for anterior glenohumeral instability at a pediatric tertiary care hospital between 2000 and 2020 were included. The analysis was conducted using a multivariate Cox proportional hazards model, with percentage of patients with recurrent instability requiring a re-operation evaluated in a time-to-event analysis as the outcome. The effects from the Cox model were expressed as the hazard ratio (HR). All tests were 2-sided, with an alpha level of .05.
Results:
A total of 488 adolescent patients (78% male; mean age: 16.9 +/- 1.98 years) met study criteria, with the most common primary sports consisting of football (n=141, 29%), hockey (n=47, 10%), basketball (n=40, 8%), baseball (n=33, 7%), and lacrosse (n=30, 6%). A total of 270 (55%) athletes participated in contact sports, while 95 (20%) were overhead athletes. Overall, 86 patients (17.6%) required revision stabilization surgery for recurrent instability, with a cumulative risk of 8.8% at 2 years, 16.5% at 5 years, and 20% at 15 years. The revision stabilization procedures occurred at a mean of 31.1 +/- 25.1 months from the index procedure and consisted of open Latarjet (n=42, 49%), revision arthroscopic stabilization (n=24, 28%), or open capsulorraphy (n=20, 23%). Risk factors for recurrent instability requiring revision stabilization included more than 1 dislocation episode prior to the index procedure (2 dislocations: HR=7.4 (2.5-21.6), p=0.0003; 3+ dislocations: HR=10.9 (3.9 to 30.5), p<0.0001), presence of a Hill-Sachs lesion (small Hill-Sachs: HR=2.5 (1.2-5.1), p=0.0114; medium-large Hill-Sachs: HR=4.2 (1.9-9.3), p=0.0004), younger age at the time of the index stabilization procedure (one year decrease in age: HR=1.2 (1.1-1.4), p=0.0015), and participation in contact sports (HR=1.8 (1.1-2.9), p=0.01). Adolescents who had sustained 1 dislocation prior to surgery had a cumulative incidence of revision surgery (3.2%) that was significantly lower than those who had sustained 2 dislocations (24.2%) or 3+ dislocations (33.5%).
Conclusions:
The number of dislocation episodes prior to index arthroscopic Bankart repair was the strongest risk factor for recurrent instability requiring revision surgery in adolescents with anterior glenohumeral instability, with two dislocation episodes conferring more than 7-fold increased risk compared to those who had just a single dislocation episode preoperatively. Other significant risk factors included the presence of a Hill-Sachs lesion, younger age, and participation in contact sports. These data support consideration for arthroscopic stabilization for adolescents following a single dislocation, especially in younger patients, contact athletes or when a Hill Sachs lesion is present.
Journal Article
Fluid Extravasation in Shoulder Arthroscopic Surgery: A Systematic Review
2018
Background:
Arthroscopic surgery of the shoulder joint has become increasingly more common given its advantages over open surgery; however, one rare but potentially life-threatening complication is fluid extravasation into the surrounding tissues, causing edema, respiratory compromise, abnormal results on laboratory blood tests, and possibly death. Currently, no systematic review exists that summarizes the existing clinical research on this topic.
Purpose:
To perform a systematic review on fluid extravasation as a complication of shoulder arthroscopic surgery, specifically assessing clinical presentation, risk factors, management, and outcomes.
Study Design:
Systematic review; Level of evidence, 4.
Methods:
Two reviewers independently searched 3 databases (PubMed, Ovid [MEDLINE], and Embase) from database inception until July 1, 2017. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist guided the reporting and data abstraction. The methodological quality of these studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS) checklist. The results are presented in a narrative summary fashion using descriptive statistics including ranges and agreement statistics.
Results:
A total of 26 studies (20 case reports, 4 case series, and 2 prospective comparative studies) encompassing 205 patients (mean age, 50.8 years [range, 15-83 years]) were included. The most common signs of fluid extravasation included chest wall swelling (n = 86) and neck swelling (n = 116). In 32 patients, observation alone was sufficient. Other patients required airway intubation (n = 16), diuretics (n = 7), steroids (n = 1), and percutaneous drainage of fluid (n = 1). Clinical edema resolved after 2 to 48 hours, and patients were discharged 1 to 20 days postoperatively. Serious complications included transfer to the intensive care unit (n = 14), anterior interosseous nerve palsy (n = 4), rhabdomyolysis (n = 1), and death (n = 1).
Conclusion:
Fluid extravasation has the potential to be a life-threatening complication of shoulder arthroscopic surgery; however, it is most commonly managed nonoperatively, and symptoms typically resolve with no evidence of long-term complications. Intraoperative surgical decisions, such as minimizing the surgical time and volume of irrigation fluid used, may limit fluid extravasation, while careful intraoperative monitoring may facilitate prompt diagnosis and management to optimize patient outcomes.
Journal Article
Diagnosis and Management of Little League Shoulder: A Systematic Review
by
Ayeni, Olufemi R.
,
Kay, Jeffrey
,
Bednar, E. Dimitra
in
Athletes
,
Medical diagnosis
,
Orthopedics
2021
Background:
Little League shoulder (LLS) is an overuse injury characterized by throwing-related pain that commonly presents in adolescent male athletes. Investigations into the optimal duration of rest from throwing and protocols for graduated return to sports (RTS) are lacking.
Purpose:
To summarize the current literature with respect to the diagnosis, management, RTS, and return to throwing for LLS.
Design:
Systematic review; Level of evidence, 4.
Methods:
The databases EMBASE, MEDLINE, and PubMed were searched between inception and April 22, 2020. References of retrieved records were reviewed for potentially eligible studies. English-language studies that reported the diagnosis and/or management of LLS in children or adolescents were included. Studies of animals or cadavers, review articles, and non—peer reviewed records were excluded. Data were summarized narratively using descriptive statistics.
Results:
Overall, 23 studies (21 level 4 studies, 2 level 3 studies) met the criteria for a total of 266 participants with a weighted mean age of 12.8 years (range, 7.4-17 years). Treatment recommendations evolved from prolonged rest and complete cessation of throwing to shorter periods of rest and graduated RTS. Less than half (11/23) of studies reported specific criteria to RTS; 1 case report discussed a coaching strategy to resume throwing, and 1 case report discussed a regimented throwing program. The proportion of participants returning to any sport participation was 94.0% (n = 157/167). The proportion returning to their preinjury level of sport was 92.5% (n = 123/133). Upon RTS, 18.7% (n = 35/187) of participants experienced a recurrence of symptoms. Premature closure of the epiphysis was reported in 1 participant.
Conclusion:
Young athletes with LLS may return to play after a period of rest, and a high proportion return to their preinjury level of sport. Further prospective studies are warranted to develop evidence-based, graduated RTS protocols and to better capture any long-term sequelae of the condition.
Journal Article
Suprascapular Nerve Blockade for Postoperative Pain Control After Arthroscopic Shoulder Surgery: A Systematic Review and Meta-analysis
2018
Background:
Regional nerve blocks are commonly used to manage postoperative pain after arthroscopic shoulder procedures. The interscalene brachial plexus block (ISB) is commonly used; however, because of the reported side effects of ISB, the use of a suprascapular nerve block (SSNB) has been described as an alternative strategy with fewer reported side effects.
Purpose:
To examine the efficacy of SSNB for pain control after shoulder arthroscopy compared with ISB as well as anesthesia without a nerve block.
Study Design:
Systematic review; Level of evidence, 1.
Methods:
Three databases (PubMed, MEDLINE, and EMBASE) were searched on April 20, 2018, to systematically identify and screen the literature for randomized controlled trials (RCTs). A meta-analysis of standard mean differences (SMDs) was performed to pool the estimated effects of the nerve blocks.
Results:
The search identified 14 RCTs that included 1382 patients, with a mean age of 54 years (SD, 13 years). The mean follow-up time was 3 days (range, 24 hours to 6 weeks). Postoperative pain control was significantly more effective in the SSNB groups compared with the control groups within 1 hour (SMD, –0.76; 95% CI, –1.45 to –0.07; P = .03) and 4 to 6 hours (SMD, –0.81; 95% CI, –1.53 to –0.09; P = .03) postoperatively. However, pain control was significantly less effective in the SSNB groups compared with ISB within 1 hour (SMD, 0.87; 95% CI, 0.28 to 1.46; P = .004). No major complications were noted in the SSNB groups, and minor complications such as hoarseness and prolonged motor block were significantly less common for SSNB compared with ISB.
Conclusion:
Although not more efficacious than ISB in terms of pain control for patients undergoing shoulder arthroscopy, SSNB provides significantly improved pain control in comparison with analgesia without a nerve block. Moreover, few major and minor complications are associated with SSNB reported across the literature.
Journal Article