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Purpose: To examine variables that predict posttraumatic growth (PTG) in individuals with parents with chronic mental illness. Method: The current cross-sectional study included 87 individuals whose parents were registered patients at the community mental health center of a training and research hospital in Kocaeli, Türkiye. Data were collected using a Demographic Information Form, the Posttraumatic Growth Inventory, Resilience Scale for Adults, Life Orientation Test, and Family Sense of Cohesion Scale. Results: Life orientation and family sense of cohesion were determined to be variables that significantly predicted PTG among participants. Conclusion: PTG was significantly influenced by life orientation and family sense of cohesion. Providing psychosocial support to individuals with parents with chronic mental illness from early childhood onward is crucial for preventive mental health.

Objective To investigate the effect of COVID‐19 on sexual dysfunction in women. Material and Methods The women diagnosed with COVID‐19 and hospitalised at a tertiary hospital were included. They completed the Introductory Data Form, the Female Sexual Function Index‐(FSFI) and the Short Form‐36 Quality of Life Scale (SF‐36). Results Fifteen women between the ages of 19‐49 who completed the treatment protocol, discharged at least 14 days before and who had not been diagnosed as sexual dysfunction; sexually active earlier were included in the study. It was detected that weekly sexual intercourse before and after COVID‐19 significantly differed (P = .047). The frequency of relationships decreased statistically after COVID‐19. The mean value of the FSFI satisfaction score differs from COVID‐19 before and after diagnosis (P = .012). The mean satisfaction score before COVID‐19 was 3.47, and after COVID‐19 was 2.93. The score of the subgroups of FSFI did not differ from COVID‐19 before and after diagnosis (P > .050). The median value of SF‐36 pain differs from COVID‐19 before and after diagnosis (P = .008). Conclusion It was concluded that the frequency of sexual intercourse and sexual satisfaction in women decreased after COVID‐19 disease, and the quality of life scores did not change in a statistically significant way.

Background/Objectives: Urinary system stone disease is an important health problem both clinically and economically due to its high recurrence rates. In this study, an innovative hybrid approach based on deep learning is proposed to predict the recurrence risk of stone disease. Methods: Patient data were divided into three subsets: anthropometric measurements (Part A), derived body composition indices (Part B), and other clinical and demographic information (Part C). Each data subset was processed with autoencoder models, and low-dimensional, meaningful features were extracted. The obtained features were combined, and the classification process was performed using four different machine learning algorithms: Extreme Gradient Boosting (XGBoost), Cubic Support Vector Machines (Cubic SVM), k-Nearest Neighbor algorithm (KNN), and Decision Tree (DT). Results: According to the experimental results, the highest classification performance was obtained with the XGBoost algorithm. The suggested approach adds to the literature by offering a novel solution that makes early risk calculation for stone disease recurrence easier. It also shows how well structural feature engineering and deep representation can be integrated in clinical prediction issues. Conclusions: Prediction of the stone recurrence risk in advance is of great importance both in terms of improving the quality of life of patients and reducing the unnecessary diagnostic evaluations along with lowering treatment costs.

Objective: In this study, it was aimed to show the changes in the sexual function of the male patients who underwent ureterorenoscopic (URS) and who had JJ stent (DJS) because of ureteral calculi and their spouses before and after the procedure. Methods: The male patients and their spouses who were admitted to the Urology Outpatient Clinic of Eskişehir State Hospital between May and August 2018 due to unilateral ureteral stones were included in the study. In order to determine sexual life, all of the male patients filled the International Index of Erectile Function (IIEF) form while their spouses filled the Female Sexual Function Index (FSFI) form. The patients with DJS and their spouses completed the forms just before the removal of DJS while the patients without DJS and their spouses filled the same forms 4 weeks after the procedure. The patients who were applied DJS after the operation of URS were defined as the study group, the patients who were not applied DJS after the operation of URS were defined as the control group. Results: Thirty one (34.4%) of 90 males who participated in the study were included in the study group. Fifty nine males (65.6%) without DJS included in the control group. There was no statistically significant difference between preoperational and post-operational scores of the male patients and their spouses on the scales of IIEF and FSFI, respectively (p>0.05). There was statistically significant decreases in the postoperational total and subscale scores of the male patients on the IIEF scale and the female patients on the FSFI scale compared to their total and subscale pre-operational scores (p<0.001). Conclusion: The male patients should be informed about their sexual life before endo-urologic procedures while their spouses should be informed about their sexual life after the procedure. DJSs should not be inserted except unavoidable circumstances; if they are inserted, they should be removed as soon as possible for minimizing their effects on the sexual lives of couples.

Background: Cyclophosphamide (CP) is a well-known alkylating anticancer agent used in the treatment of various malignant and non-malignant tumors. CP may also cause a variety of adverse effects, including reproductive toxicity. Amifostine is known as a cytoprotective drug having antioxidant properties. Objective: To evaluate the possible beneficial effects of amifostine on testicular toxicity induced by CP in rats. Materials and Methods: A total of 35 Sprague-Dawley rats were used in this experimental study. The CP group animals received a single dose of 200 mg/kg CP on Day 8 by intraperitoneal injection and were left untreated for the following seven days. The two remaining groups of animals were treated with 200 mg/kg/day amifostine (AMF 200) and 400 mg/kg/day amifostine (AMF 400) for seven days prior to and following a single intraperitoneal injection of CP. Morphometrical analysis and histological examination of testicular tissue were performed. Serum testosterone, luteinizing hormone, and follicle-stimulating hormone levels were measured in serum using commercial ELISA kits. The epidydimal sperm count was determined. Results: The tubular epithelial height in the testis was significantly higher in the AMF400 group compared to other groups (p < 0.001). Animals in the AMF400 group showed minimal debris in the tubules, no Sertoli cell damage, and the Johnsen scores were slightly higher in the AMF400 group. The epididymal sperm count was significantly lower in the CP-administered animals compared to the control animals and was significantly higher in the AMF200 and AMF400 groups compared to the CP group (p = 0.006, and p = 0.019 respectively). Conclusion: Amifostine, at a dose of 400 mg/kg, may have a protective effect on testicular damage induced by CP in rats.

Purpose To find the machine learning (ML) method that has the highest accuracy in predicting the semen quality of men based on basic questionnaire data about lifestyle behavior. Methods The medical records of men whose semen was analyzed for any reason were collected. Those who had data about their lifestyle behaviors were included in the study. All semen analyses of the men included were evaluated according to the WHO 2021 guideline. All semen analyses were categorized as normozoospermia, oligozoospermia, teratozoospermia, and asthenozoospermia. The Extra Trees Classifier, Average (AVG) Blender, Light Gradient Boosting Machine (LGBM) Classifier, eXtreme Gradient Boosting (XGB) Classifier, Logistic Regression, and Random Forest Classifier techniques were used as ML algorithms. Results Seven hundred thirty-four men who met the inclusion criteria and had data about lifestyle behavior were included in the study. 356 men (48.5%) had abnormal semen results, 204 (27.7%) showed the presence of oligozoospermia, 193 (26.2%) asthenozoospermia, and 265 (36.1%) teratozoospermia according to the WHO 2021. The AVG Blender model had the highest accuracy and AUC for predicting normozoospermia and teratozoospermia. The Extra Trees Classifier and Random Forest Classifier models achieved the best performance for predicting oligozoospermia and asthenozoospermia, respectively. Conclusion The ML models have the potential to predict semen quality based on lifestyles.

Background This study aimed to systematically compare the most recent guidelines from the European Association of Urology (EAU, 2025), American Urological Association (AUA, 2024), and National Comprehensive Cancer Network (NCCN, 2025) for the management of non-muscle invasive bladder cancer (NMIBC). The primary objective was to assess the degree of concordance and identify sources of divergence across 32 predefined clinical decision domains. Materials and methods This guideline concordance study was conducted according to PRISMA 2020 recommendations, evaluating full-text versions of the latest EAU, AUA, and NCCN guidelines. Thirty-two clinical domains encompassing the diagnostic, therapeutic, and follow-up aspects of NMIBC management were pre-defined based on literature review and expert consensus. Two independent reviewers classified each domain for each guideline as full concordance, partial concordance, or discordance, with discrepancies resolved by a third reviewer. Inter-guideline agreement was quantified using Cohen’s and Fleiss’ kappa coefficients. Results Among the 32 domains analyzed, full concordance was identified in 19 domains (59.4%), partial concordance in 12 domains (37.5%), and discordance in 1 domain (3.1%). Inter-guideline reliability was high, with Cohen’s kappa values ranging from 0.83 to 0.94 across pairs and an overall Fleiss’ kappa of 0.74, indicating substantial agreement among the three guidelines. Clinically meaningful differences were mainly related to risk-stratification criteria, the management of BCG-unresponsive disease, the selective use of urinary biomarkers, and the endorsement of conservative strategies for recurrent low-grade tumors. Conclusion Current international guidelines for NMIBC are highly consistent across the majority of clinical decision domains, providing a strong framework for evidence-based care. Residual differences reflect evolving evidence, regulatory environments, and the pace of integration of new diagnostics and therapeutics. Continued harmonization efforts and regular guideline updates are necessary to further optimize global NMIBC management.

Aim Operative dictation (OD) is a critical component of surgical documentation, yet its formal teaching is often overlooked in residency training. This study aimed to evaluate the inclusion of OD training in urology residency programs and assess awareness and practices among urology residents (URs) and staff urologists (SUs). Materials and methods A structured questionnaire was developed to explore OD practices, awareness, and training methods. The questionnaire consisted of four sections: demographic characteristics, OD practices, awareness of OD as a skill, and formal OD training. It was distributed via e-mail to URs and SUs whose contact information was obtained from the Turkish Urological Association’s Central Anatolia Branch. Descriptive statistics were used to analyze the data. Results The survey was sent to 252 participants and achieved a response rate of 86.9% ( n  = 219). Among the respondents, 61 were URs (27.8%) and 158 were SUs (72.1%). Most participants (96.7% of URs and 98.2% of SUs) reported no formal OD training during residency, informal methods, such as reviewing old ODs and guidance from senior residents, were commonly cited as learning approaches. Despite recognizing the importance of structured OD templates, participants highlighted the absence of standardized training curricula. Similar responses from experienced and novice surgeons suggest that this gap has persisted for decades. Conclusion This study highlights the lack of formal OD training in urology residency programs and the reliance on informal methods. Integrating standardized OD training modules into residency curricula is essential to improve documentation quality and medico-legal reliability. Future research should explore the effectiveness of educational interventions and develop universal guidelines for OD practices. Clinical trial number Not applicable.

Aims To evaluate the diagnostic significance of the novel index combining preoperative haemoglobin, albumin levels, lymphocyte and platelet counts (HALP) in prostate cancer (PCa) patients. Methods Between 1 January 2015 to 31 December 2018 at the Hitit University Erol Olçok Education and Research Hospital 225 patients who had undergone transrectal ultrasound guided prostate biopsy or prostate surgery were analysed retrospectively. A total of patients, 155 had benign prostate hyperplasia (group 1) and 70 had PCa (group 2). The preoperative serum levels of haemoglobin, albumin, lymphocyte counts and platelet counts were recorded. The HALP scores and the sub‐parameters of this index for each of the two groups were compared. Results The total Prostate‐Specific Antigen (PSA), albumin and lymphocyte differences between the groups were statistically significant (P = 0.0002, P = 0.0001, P = 0.005). The median value of HALP scores in Group 1 and 2 were 49.43 and 51.2, respectively, and this was not statistically significant between groups (P =0 .737). The HALP score had the least Area Under Curve (AUC) value compared with the others (0.514). The AUC of Albumin was larger than PSA for diagnostic efficacy in PCa patients (0.696‐0.656). However, albumin levels were statistically significant compared with platelet count and the HALP score (P = 0.0033, P = 0.0068), except PSA and lymphocyte (P = 0.4580, P =0 .1717). Conclusion Further prospective clinical studies that include more patients from multiple centres are needed to show the diagnostic role of the HALP score and its compounds on the patients with PCa.

The presence of endometrial stroma and/or glandular epithelium in organs other than the uterus is called endometriosis. Urinary system endometriosis is observed in approximately 1% of women with endometriosis and is most commonly seen in the bladder. A 27-year-old female patient was admitted to the urology clinic with cyclic complaints of painful and frequent urination. Ultrasonography revealed a lesion extending to the lumen of approximately 15x10 mm in the left side wall of the bladder. On cystoscopy, a suspicious area with irregular borders was observed, approximately 15 mm, at the left-posterior lateral wall of the bladder, and transurethral resection was performed. The pathological result of the patient was reported as bladder endometriosis. Although rare, bladder endometriosis should be considered in the differential diagnosis, especially in women of reproductive age with cyclic urological complaints.