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Owing to the mixed electron/hole and ion transport in the aqueous environment, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)-based organic electrochemical transistor has been regarded as one of the most promising device platforms for bioelectronics. Nonetheless, there exist very few in-depth studies on how intrinsic channel material properties affect their performance and long-term stability in aqueous environments. Herein, we investigated the correlation among film microstructural crystallinity/composition, device performance, and aqueous stability in poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) films. The highly organized anisotropic ordering in crystallized conducting polymer films led to remarkable device characteristics such as large transconductance (∼20 mS), extraordinary volumetric capacitance (113 F·cm −3 ), and unprecedentedly high [ μC * ] value (∼490 F·cm −1 V −1 s −1 ). Simultaneously, minimized poly(styrenesulfonate) residues in the crystallized film substantially afforded marginal film swelling and robust operational stability even after >20-day water immersion, >2000-time repeated on-off switching, or high-temperature/pressure sterilization. We expect that the present study will contribute to the development of long-term stable implantable bioelectronics for neural recording/stimulation. The lack of understanding of mixed transport in ion-permeable conjugated polymer films hinders the advance of organic electrochemical transistors for bioelectronics. Here, the authors elucidate the structure-property-performance relationships for conventional and crystallized PEDOT:PSS films.

Purpose The concept of leader–member exchange (LMX) is well accepted in the service industry. This study examines how the quality of LMX helps hotels to achieve desirable outcomes, such as innovative behavior and job performance. The model was developed based on the LMX theory, and considers the relationship among the quality of LMX, employee engagement, innovative behavior and job performance. Design/methodology/approach The model was tested on employees of hotels in South Korea using a survey method. Data were analyzed using frequency, reliability, confirmatory factor, correlation and structural equation modeling analyses. Findings LMX significantly influenced job engagement and innovative behavior but did not significantly affect organization engagement. Job engagement significantly affected organization engagement and innovative behavior but did not significantly influence job performance. Organization engagement significantly influenced job performance but did not significantly affect innovative behavior. Job performance was significantly influenced by innovative behavior. Practical implications The findings of this study suggest that an immediate leader plays a critical role in fostering engagement, behavior and performance. Originality/value The current study is the first to use the LMX theory to develop and test a research model that accounts for the antecedents and desired outcomes (i.e. innovative behavior and job performance) of two types of employee engagement in the hotel context.

Jeju Island is a popular destination in South Korea that is dependent on nature-based tourism. The annual increase in the influx of visitors has created major environmental impacts due to overuse and commercial expansion. With projected growth in arrivals and the development of tourism infrastructure, the island will experience perpetual challenges for sustainable management of natural resources. However, the role of visitors will be central via a commitment to practice pro-environmental behaviors to protect the island from further degradation. This study was grounded in the cognition-affection-attitude-behavior model to examine the predictive validity of tourists’ environmental knowledge, environmental affect, and nature affiliation on pro-environmental behavior. The data comprised responses from 304 domestic visitors who had visited Jeju Island. The empirical findings indicate that environmental affect was significantly impacted by two dimensions of environmental knowledge (i.e., subjective and objective). Additionally, nature affiliation was positively impacted by environmental affect, while pro-environmental behavior was significantly influenced by both environmental affect and nature affiliation. Overall, these findings provide theoretical and practical implications for sustainable tourism at a nature-based destination. The findings can be utilized for implementation of intervention programs and visitor management at Jeju Island.

Corporate social responsibility (CSR) has become a major part of the foodservice industry due to external forces which encourage enterprises’ responsiveness. In reality, consumers’ social concern influences their attitudes towards foodservice firms’ socially responsible practices and purchase decisions, thereby influencing senior management to react. Considering this issue, this study examines the impact of senior management’s ethical leadership in evaluating operational, commercial, and economic performances along with the mediating role of CSR in the foodservice industry. A conceptual model was formulated and empirically tested based on responses from 196 foodservice franchise firms in South Korea. The results indicated ethical leadership significantly influenced CSR and operational performance, while CSR also had a positive effect on operational and commercial performances. Additionally, operational performance had a significantly positive influence on commercial performance, which subsequently enhanced economic performance. Overall, the findings highlight the role that ethical leadership exhibited by senior management of foodservice franchises influenced initiation of CSR activities, which provide implications for research and industry practice and is outlined.

The behavior of airport precast concrete pavement (APCP) involving new design and construction concepts was experimentally analyzed under environmental and moving airplane loads, and the long-term performance of the APCP was evaluated using fatigue failure analysis. The strain characteristics and curling behavior of the APCP under environmental loads were comprehensively analyzed. The APCP slabs exhibited a pronounced curling phenomenon similar to conventional concrete pavement slabs. The dynamic response of the APCP subjected to impact loads was analyzed by performing heavy weight deflectometer tests. The test results confirmed that the vertical deformation of the APCP was small and within the typical range of vertical deformation of conventional concrete pavement. The dynamic strain response of the APCP under moving airplane loads was then analyzed and the strain variation during day and night times was compared. The strains during the day were found to be significantly larger than those at night under airplane loads because of the curling phenomenon of the APCP slabs. Finally, the long-term performance of the APCP was evaluated using fatigue failure analysis based on the obtained behavior. Even using the most conservative fatigue failure prediction model, the service life of the APCP was ascertained to be more than 30 years. Based on the overall results of this study, it is concluded that the APCP, which is designed to reduce slab thickness by placing reinforcing bars in the slabs via reinforced concrete structural design, exhibits typical behavior of concrete pavements and can be successfully applied to airport pavement rehabilitation.

Among the construction processes of Portland cement concrete pavement (PCCP), the curing compound spraying process is one of the most important processes. If the curing compound spraying amount does not meet the standard or if the curing compound is not applied evenly, distresses occur at the early age of construction, ultimately causing deterioration in concrete pavement performance. The purpose of this study is to develop a real-time monitoring system for a curing compound spraying process based on the Internet of Things (IoT) and sensing technologies to improve the construction quality of concrete pavement. To achieve the goal of this research, we conducted various laboratory and field experiments. The curing compound spraying amount and sprayed status were measured and analyzed using flowmeters, image acquisition sensors, and an image processing program, and the data were provided to workers in real time and simultaneously transmitted to the IoT cloud to form a database. From this study, it is confirmed that the IoT-technology-based curing compound spraying amount and sprayed status monitoring systems can be successfully established to manage construction quality related to the curing of concrete pavement.

We previously demonstrated that ibrutinib modulates LPS‐induced neuroinflammation in vitro and in vivo, but its effects on the pathology of Alzheimer's disease (AD) and cognitive function have not been investigated. Here, we investigated the effects of ibrutinib in two mouse models of AD. In 5xFAD mice, ibrutinib injection significantly reduced Aβ plaque levels by promoting the non‐amyloidogenic pathway of APP cleavage, decreased Aβ‐induced neuroinflammatory responses, and significantly downregulated phosphorylation of tau by reducing levels of phosphorylated cyclin‐dependent kinase‐5 (p‐CDK5). Importantly, tau‐mediated neuroinflammation and tau phosphorylation were also alleviated by ibrutinib injection in PS19 mice. In 5xFAD mice, ibrutinib improved long‐term memory and dendritic spine number, whereas in PS19 mice, ibrutinib did not alter short‐ and long‐term memory but promoted dendritic spinogenesis. Interestingly, the induction of dendritic spinogenesis by ibrutinib was dependent on the phosphorylation of phosphoinositide 3‐kinase (PI3K). Overall, our results suggest that ibrutinib modulates AD‐associated pathology and cognitive function and may be a potential therapy for AD. This study evaluated the effects of ibrutinib on Aβ/tau pathology and cognitive function in two mouse models of Alzheimer's disease (AD). Ibrutinib reduced tau phosphorylation, neuroinflammation, or Aβ accumulation in 5xFAD mice and PS19 mice. Interestingly, ibrutinib injection improved long‐term memory and dendritic spine number in 5xFAD mice. Moreover, the induction of spinogenesis by ibrutinib was dependent on PI3K phosphorylation. These data suggest that ibrutinib holds potential as a therapeutic drug for AD.

Although a variety of beneficial health effects of natural flavonoids, including chrysin, has been suggested, poor solubility and bioavailability limit their practical use. As a promising delivery system, chrysin-loaded phytosomes (CPs) were prepared using egg phospholipid (EPL) at a 1:3 molar ratio and its antidiabetic effects were assessed in db/db diabetic mice. Male C57BLKS/J-db/db mice were fed a normal diet (control), chrysin diet (100 mg chrysin/kg), CP diet (100 mg chrysin equivalent/kg), metformin diet (200 mg/kg) or EPL diet (vehicle, the same amount of EPL used for CP preparation) for 9 weeks. Administration of CP significantly decreased fasting blood glucose and insulin levels in db/db mice compared with the control. An oral glucose tolerance test and homeostatic model assessment for insulin resistance were significantly improved in the CP group (p < 0.05). CP treatment suppressed gluconeogenesis via downregulation of phosphoenolpyruvate carboxykinase while it promoted glucose uptake in the skeletal muscle and liver of db/db mice (p < 0.05). The CP-mediated improved glucose utilization in the muscle was confirmed by upregulation of glucose transporter type 4, hexokinase2 and peroxisome proliferator-activated receptor γ during treatment (p < 0.05). The CP-induced promotion of GLUT4 plasma translocation was confirmed in the skeletal muscle of db/db mice (p < 0.05). Based on the results, CP showed greater antidiabetic performance compared to the control by ameliorating insulin resistance in db/db mice and phytosome can be used as an effective antidiabetic agent.

Accurate representation of Precipitable Water Vapor (PWV) in numerical models is critical over the meteorologically complex Korean Peninsula, yet validation remains a challenge. This study presents a unique airborne validation of hourly PWV from two local Numerical Weather Prediction (NWP) models—the Local Data Assimilation and Prediction System (LDAPS) and the Korea Local Analysis and Prediction System (KLAPS)—and two global reanalysis datasets—the ECMWF Reanalysis v5 (ERA5) and the Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2). We utilize a G-band Water Vapor Radiometer (GVR) and dropsondes, applying a rigorous multi-stage quality control (QC) procedure to ensure data reliability. Two strategies were used: comparing GVR-measured upper-column PWV against model layers and comparing a total-column GVR–dropsonde composite against the models’ total PWV. Our key finding reveals that the ERA5 reanalysis consistently provides the most accurate representation of both upper-air and total column PWV. In contrast, the high-resolution local models exhibit significant dry biases, particularly in moist and cloudy conditions. These results underscore the value of airborne validation and suggest that for water vapor analysis over Korea, ERA5 serves as a more reliable benchmark than local models, highlighting the need to improve humidity assimilation and microphysics in regional systems.