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Aim In this study, it was aimed to explore the prognostic factors in patients who received selective internal radiation therapy for hepatocellular cancer. Materials and methods A retrospective evaluation was made of 28 (24 male, 4 female, mean age 65.4 ± 6.8 years) hepatocellular cancer patients who received selective internal radiation therapy with Y-90 resin microspheres. Using Cox proportional hazards regression analysis, the relationship between age, gender, MELD score, serum albumin and AFP levels, number of liver lesions, size of the largest lesion, absence of 18 F-FDG uptake, maximum standardized uptake value and overall survival times was analyzed. Results Treatment was applied to the right lobe in 22 and both in 6 patients. Mean treatment dose was 1.5 ± 0.2 GBq. Number of liver lesions were 1, <5 and multiple in 16, 5 and 7 patients, respectively, and the mean size of the largest lesion was 41.5 mm (min–max 15–160 mm). While 18 F-FDG uptake was seen in 24 patients, liver lesions were hypometabolic in 4 patients. Mean SUV max of liver lesions was calculated as 5.3 ± 0.3. During the mean 17.8 (min–max 2–39) months follow-up period, 19 patients died. Median survival time was computed as 18 ± 5 months (95 % CI 8.1–27.8). Age ( p  = 0.04), serum AFP level ( p  = 0.03) and size of the largest lesion ( p  = 0.02) had a significant negative effect on survival according to the Cox proportional hazards regression analysis. Conclusion Age, serum AFP level and the size of the largest liver lesion have a negative significant effect on survival of hepatocellular cancer patients who received selective internal radiation therapy.

Purpose To investigate the relationship between cell content and histopathological features of parathyroid lesions and 18F-FCH uptake intensity on PET/CT images. Methods Patients with primary hyperparathyroidism (age > 18) who were referred to 18F-FCH PET/CT were involved. All patients underwent parathyroidectomy. Correlation of SUVmax with following factors were statistically analysed: serum PTH, Ca, P levels and histopathological parameters, total absolute amounts of chief cell, oxyphyllic cell and clear cell components calculated by the multiplication of the volume of the parathyroid lesion and the percentage of each type of cell content (called as Absolute chief , Absolute oxyphyllic and Absolute clear reflecting the total amount of each cell group). Results A total of 34 samples from 34 patients (6M, 28F, mean age: 53.32 ± 15.15, min: 14, max: 84) who had a positive 18F-FCH PET/CT localizing at least one parathyroid lesion were involved. In the whole study group, SUVmax was found to be correlated with the greatest diameter and volume of the lesion and Absolute chief ( p  = 0.004, p  = 0.002 and p  = 0.035, respectively). In the subgroup analysis of 28 samples with longest diameter > 1 cm, the correlation between SUVmax and Absolute chief remained significant ( p  = 0.036) and correlation between SUVmax and volume and longest diameter became stronger ( p  = 0.011 and p  > 0.001, respectively). No correlation was found between SUVmax and Absolute oxyphyllic or Absolute clear . Conclusions There might be a relationship between 18F-FCH uptake intensity and chief cell content in patients with parathyroid adenoma. Further studies with larger patient groups would be beneficial to support the data.

Discussion Cardiac hydatid cysts are extremely rare particularly in the pediatric age. Because of its potential risk for rupture resulting in systemic or pulmonary dissemination, embolism or anaphylactic shock, prompt diagnosis and early surgery is crucial.