Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
3,700
result(s) for
"Kirk, H"
Sort by:
Observing writing : insights from keystroke logging and handwriting
\"Observing Writing: Insights from Keystroke Logging and Handwriting is a timely volume appearing twelve years after the Studies in Writing volume Computer Keystroke Logging and Writing (Sullivan & Lindgren, 2006). The 2006 volume provided the reader with a fundamental account of keystroke logging, a methodology in which a piece of software records every keystroke, cursor and mouse movement a writer undertakes during a writing session. This new volume highlights current theoretical and applied research questions in keystroke logging and handwriting research that observes writing. In this volume, contributors from a range of disciplines, including linguistics, psychology, neuroscience, modern languages, and education, present their research that considers the cognitive and socio-cultural complexities of writing texts in academic and professional settings\"-- Provided by publisher.
Book
In situ process quality monitoring and defect detection for direct metal laser melting
Quality control and quality assurance are challenges in direct metal laser melting (DMLM). Intermittent machine diagnostics and downstream part inspections catch problems after undue cost has been incurred processing defective parts. In this paper we demonstrate two methodologies for in-process fault detection and part quality prediction that leverage existing commercial DMLM systems with minimal hardware modification. Novel features were derived from the time series of common photodiode sensors along with standard machine control signals. In one methodology, a Bayesian approach attributes measurements to one of multiple process states as a means of classifying process deviations. In a second approach, a least squares regression model predicts severity of certain material defects.
Journal Article
Visions of lost worlds : the paleoart of Jay Matternes
\"A lavish showcase of paleoartist Jay Matternes's spectacular murals and sketches For half a century, the artwork of Jay Matternes adorned the fossil halls of the Smithsonian National Museum of Natural History. Most prominent among his work was a set of immense murals documenting the story of mammal evolution over the past 56 million years. Matternes also worked with sculptor Neal Deaton to construct three dioramas showing environments from each of the major time periods of the Mesozoic Era. These treasured Matternes murals and dioramas are significant works of one of the most influential paleoartists in history. Simultaneously epic in size and scope and minutely detailed, they also provide a window into the study and interpretation of vertebrate paleontology and paleoecology. Visions of Lost Worlds presents these unparalleled works of art, and also includes the sketches and drawings Matternes prepared as he planned the murals. Known for his technical genius and eye for detail, Matternes sketched from skeletons in museum collections and added muscle, skin, and fur to bring mammals and dinosaurs from prehistory to vivid life. This book offers a close look at these works of art, a peek inside the artist's process, and an examination of the works' impact and legacy\"-- Provided by publisher.
Book
Chemically homogeneous and thermally reversible oxidation of epitaxial graphene
With its exceptional charge mobility, graphene holds great promise for applications in next-generation electronics. In an effort to tailor its properties and interfacial characteristics, the chemical functionalization of graphene is being actively pursued. The oxidation of graphene via the Hummers method is most widely used in current studies, although the chemical inhomogeneity and irreversibility of the resulting graphene oxide compromises its use in high-performance devices. Here, we present an alternative approach for oxidizing epitaxial graphene using atomic oxygen in ultrahigh vacuum. Atomic-resolution characterization with scanning tunnelling microscopy is quantitatively compared to density functional theory, showing that ultrahigh-vacuum oxidization results in uniform epoxy functionalization. Furthermore, this oxidation is shown to be fully reversible at temperatures as low as 260 °C using scanning tunnelling microscopy and spectroscopic techniques. In this manner, ultrahigh-vacuum oxidation overcomes the limitations of Hummers-method graphene oxide, thus creating new opportunities for the study and application of chemically functionalized graphene.
Graphene oxide produced via the standard Hummers method possesses a high degree of chemical inhomogeneity and limited reversibility. Now, it has been shown that an alternative ultra-high-vacuum approach for oxidizing epitaxial graphene yields uniform epoxy functionalization with thermal reversibility at temperatures as low as 260 °C.
Journal Article
Space chimps
A trio of chimpanzees are recruited to retrieve a wayward space probe and find themselves having to save the peaceful inhabitants of a distant planet from an evil dictator.
DVD
Phylogenetic resolution of the fly superfamily Ephydroidea–Molecular systematics of the enigmatic and diverse relatives of Drosophilidae
The schizophoran superfamily Ephydroidea (Diptera: Cyclorrhapha) includes eight families, ranging from the well-known vinegar flies (Drosophilidae) and shore flies (Ephydridae), to several small, relatively unusual groups, the phylogenetic placement of which has been particularly challenging for systematists. An extraordinary diversity in life histories, feeding habits and morphology are a hallmark of fly biology, and the Ephydroidea are no exception. Extreme specialization can lead to “orphaned” taxa with no clear evidence for their phylogenetic position. To resolve relationships among a diverse sample of Ephydroidea, including the highly modified flies in the families Braulidae and Mormotomyiidae, we conducted phylogenomic sampling. Using exon capture from Anchored Hybrid Enrichment and transcriptomics to obtain 320 orthologous nuclear genes sampled for 32 species of Ephydroidea and 11 outgroups, we evaluate a new phylogenetic hypothesis for representatives of the superfamily. These data strongly support monophyly of Ephydroidea with Ephydridae as an early branching radiation and the placement of Mormotomyiidae as a family-level lineage sister to all remaining families. We confirm placement of Cryptochetidae as sister taxon to a large clade containing both Drosophilidae and Braulidae–the latter a family of honeybee ectoparasites. Our results reaffirm that sampling of both taxa and characters is critical in hyperdiverse clades and that these factors have a major influence on phylogenomic reconstruction of the history of the schizophoran fly radiation.
Journal Article
Impact of blood factors on endothelial cell metabolism and function in two diverse heart failure models
Role of blood-based factors in development and progression of heart failure (HF) is poorly characterized. Blood contains factors released during pathophysiological states that may impact cellular function and provide mechanistic insights to HF management. We tested effects of blood from two distinct HF models on cardiac metabolism and identified possible cellular targets of the effects. Blood plasma was obtained from daunorubicin- and myocardial infarction-induced HF rabbits (Dauno-HF and MI-HF) and their controls (Dauno-Control and MI-Control). Effects of plasma on bioenergetics of myocardial tissue from healthy mice and cellular cardiac components were assessed using high-resolution respirometry and Seahorse flux analyzer. Since endothelial cell respiration was profoundly affected by HF plasma, effects of plasma on endothelial cell barrier function and death were further evaluated. Western-blotting and electron microscopy were performed to evaluate mitochondrial proteins and morphology. Brief exposure to HF plasma decreased cardiac tissue respiration. Endothelial cell respiration was most impacted by exposure to HF plasma. Endothelial cell monolayer integrity was decreased by incubation with Dauno-HF plasma. Apoptosis and necrosis were increased in cells incubated with Dauno-HF plasma for 24 h. Down-regulation of voltage-dependent anion-selective channel (VDAC)-1, translocase of outer membrane 20 (Tom20), and mitochondrial fission factor (MFF) in cells exposed to Dauno-HF plasma and mitochondrial signal transducer and activator of transcription 3 (Stat3) and MFF in cells exposed to MI-HF plasma were observed. Mitochondrial structure was disrupted in cells exposed to HF plasma. These findings indicate that endothelial cells and mitochondrial structure and function may be primary target where HF pathology manifests and accelerates. High-throughput blood-based screening of HF may provide innovative ways to advance disease diagnosis and management.
Journal Article
A critical review of characterization and measurement of textile-grade hemp fiber
The legalization of hemp production in the United States (US) in 2018 triggered a boom of research and development to apply the newfound resource. The textile industry, one of the most notable polluters in the world, looked to hemp as a more sustainable alternative to a multitude of fibers, including cotton. After discovering the numerous benefits of hemp, demand for hemp textile production rapidly increased. However, currently, there is little to no guidance in the US for evaluating the properties of hemp to determine its ability to be made into a fiber. Fiber properties are measured for natural and synthetic fibers to ensure that the final product will perform adequately and is a necessary step in the textile production process. Therefore, to aid in the development of a more efficient industrial hemp production in the US, the purpose of this research was to evaluate the current characterization methods used for cotton, flax, wool, hemp (in China), etc. and determine their applicability for hemp textile fibers in the United States. The measurements chosen were based on the necessary information for spinning mills to produce high quality hemp fiber. Test methods of fiber length, width, linear density, tensile strength, cohesion, cleanliness, density, oil content, and color were reviewed and discussed. This review may shed new lights on the hemp fiber characterization and measurement in the textile industry.
Journal Article
Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina
Adenylyl cyclase 6 (AC6) synthesizes second messenger cAMP in G protein-coupled receptor (GPCR) signaling. In cochlear hair cells, AC6 distribution relies on an adhesion GPCR, ADGRV1, which is associated with Usher syndrome (USH), a condition of combined hearing and vision loss. ADGRV1 is a component of the USH type 2 (USH2) protein complex in hair cells and photoreceptors. However, the role of AC6 in the inner ear and retina has not been explored. Here, we found that AC6 distribution in hair cells depends on the USH2 protein complex integrity. Several known AC6 regulators and effectors, which were previously reported to participate in ADGRV1 signaling in vitro, are localized to the stereociliary compartments that overlap with AC6 distribution in hair cells. In young AC6 knockout (
Adcy6
−/−
) mice, the activity of cAMP-dependent protein kinase, but not Akt kinase, is altered in cochleas, while both kinases are normal in vestibular organs. Adult
Adcy6
−/−
mice however exhibit normal hearing function. AC6 is expressed in mouse retinas but rarely in photoreceptors.
Adcy6
−/−
mice have slightly enhanced photopic but normal scotopic vision. Therefore, AC6 may participate in the ADGRV1 signaling in hair cells but AC6 is not essential for cochlear and retinal development and maintenance.
Journal Article
Benchmarking the ragone behaviour and power performance trends of pseudocapacitive batteries
The ‘holy grail’ of energy storage is to achieve both high energy and high power densities ( ⩾ 100 Wh l −1 and ∼ 10 4 W l −1 , respectively) as characterized in a Ragone plot. However, across the macroscopic dimensions over which energy storage systems operate, power performance is fundamentally limited by both drift and diffusion processes. In this work a macroscopic variation on the Gerischer–Hopfield formalism is applied to explore how the motion of electrical charges, moving between redox species, and screening counter-ions might be engineered in a pseudocapacitive system employing quantized capacitance (in the form of a pseudocapacitive battery) to reach this long-sought metric. Our theoretical findings show that the electron diffusion timescale between redox species generally determines power performance trends when pseudocapacitive coatings are applied monolithically. This electron-diffusion–dominated timescale, in turn, is shown to scale with the square of the coating thickness. However, when conducting pathways (or shunts) are introduced to substantially reduce the mean distance for electron diffusion the Ragone performance becomes dominated by ion drift and diffusion—even when the diffusion constants of all species are held equal. The resulting trends, for this shunting regime, show a power performance timescale that scales in a more linear fashion with increasing thickness of the redox-active region. By analyzing the Ragone performance metrics for realistic coating thicknesses between these two operational regimes, the resulting findings suggest that the diffusion constants needed to achieve the aforementioned high-performance metrics are plausibly achievable for both electronic and ionic charges in this proposed class of pseudocapacitive systems.
Journal Article