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Background: This study explores the role of inflammatory hematological markers from complete blood count (CBC) parameters in predicting the in vitro fertilization (IVF) treatment success of patients. It focuses particularly on the immature granulocyte (IG) percentage, a novel inflammatory marker. To our knowledge, this is the first study in the literature examining the relationship between IG percentage and pregnancy outcomes in IVF. Methods: Conducted retrospectively, this study included 311 IVF cycles from 311 distinct patients. A binomial logistic regression model identified factors affecting pregnancy outcomes. Various predictors were analyzed, including embryo quality, white blood cell (WBC) count, IG percentage, systemic inflammatory index (SII), endometrial thickness on the day of human chorionic gonadotropin (hCG) administration, number of mature (MII) oocytes, and the number of embryos generated. Results: The IG percentage significantly impacted clinical pregnancy and live birth outcomes (OR = 0.40, 95% CI (confidence interval): 0.317–0.51, p < 0.001), unlike other inflammatory markers. Each millimeter increase in endometrial thickness measured on the day of hCG administration was associated with a slight increase in the likelihood of IVF success (OR: 1.20, 95% CI 1.004–1.44, p = 0.044). Neither SII nor mature oocyte count significantly affected pregnancy outcomes. Conclusions: A low IG percentage correlates positively with clinical pregnancy and live birth outcomes. Measuring IG percentage offers a rapid, inexpensive, and readily available method to predict IVF success.

Background The research was conducted to evaluate the birth and newborn outcomes of Syrian immigrant women according to maternal age groups and Vitamin D use. Methods It was conducted retrospectively using the birth records of 2,866 Syrian migrant women, who had given birth at a tertiary center between January 2016 and May 2020. Demographic features, obstetric and neonatal outcomes were analyzed according to age groups and Vitamin D use. Results The mean age of the patients included in the study was 26.22 ± 5.90, the mean gestational age at birth was 38.06 ± 2.1 weeks, and the mean newborn birth weight was 3.151 g. The mean hemoglobin value of the patients was 11.55 ± 1.54. While most of the patients were taking iron supplements (80.59%), Vitamin D (Vit D) supplement intake was 38.31%. The mean number of antenatal follow-ups was 3.40 ± 1.65. While the most common delivery method was normal vaginal delivery (61.93%), cesarean section rates were found to be 38.07%. The need for blood transfusion was significantly lower in the group that had received Vitamin D than that in the group that had not received it (2.00% vs. 8.94% p < 0.001). The rate of preterm birth was found to be 5.74% in the group that had received Vitamin D and 9.28% in the group that had not received it, which was significantly higher (p < 0.001). Conclusions We have seen that maternal and fetal outcomes can be improved with hospital follow-up and adequate vitamin supplements in refugee pregnant women.

This study aimed to evaluate the impact of different treatment modalities-expectant management, methotrexate (MTX), and laparoscopic salpingectomy-on the future fertility of women treated for tubal ectopic pregnancies (EP). The primary outcome was to evaluate the mean time to conception, and the secondary outcome was to evaluate live birth rates and the risk of recurrent ectopic pregnancy (REP) between treatment groups. A retrospective analysis was conducted involving 121 women treated for tubal EP from January 2020 to November 2024. The study analyzed fertility outcomes based on the treatment modality received, which included expectant management, MTX, and laparoscopic salpingectomy. Data were collected through hospital records. The time to clinical pregnancy was 255 (60-390) days in the expectant group, 270 (60-1080) days in the MTX group, and 255 (90-1440) days in the laparoscopic salpingectomy group. Median time to achieve pregnancy was 270 (95% CI: 222-318) days for all the treatment groups. No significant differences were found in the time to pregnancy across the treatment groups (p = 0.274). Out of 121 patients, 58 (47.9%) achieved pregnancy, of which 33 (27.2%) resulted in live births. Live birth rates were 75%, 58.3%, and 50% in the expectant management, MTX, and laparoscopic salpingectomy groups, respectively. Live birth rates also did not differ between the three treatment groups (p = 0.437). All the three treatment modalities did not show a statistically significant impact on the rates of REP (p = 0.42). We found no significant differences in time-to-pregnancy or live birth rates among expectant, MTX, and laparoscopic salpingectomy management for tubal EP. Given EP's significant impact on fertility in reproductive-aged women, studies comparing treatment effects on future fertility are clinically valuable.

Introduction: Tubal ligation reversal is a surgical option for restoring fertility, with outcomes influenced by technique, surgeon expertise, and patient factors. Objective: This study evaluates the fertility outcomes of macroscopic tubal reanastomosis through mini-laparotomy. Methods: This retrospective study analyzed medical records of women who had previously undergone tubal ligation either during cesarean sections or through laparoscopic electrocoagulation at a tertiary hospital in Türkiye between 2019 and 2022. The primary surgical approach involved a mini-laparotomy, and the anastomosis was performed macroscopically-without the use of an operating microscope-relying instead on direct visual inspection to access and reconnect the fallopian tubes. The suitability of the tubes for reanastomosis was assessed based on the length of the tubes, the presence of adhesion, and the condition of the fimbriae. Fertility outcomes, including live birth rates and time to conception, and surgical success rates, were measured. Results: The data of 23 patients were retrospectively reviewed. The surgical success rate was 78.2% (unilateral or bilateral reanastomosis of the tubas), with a pregnancy rate of 43.5% and a live birth rate of 34.8%. The mean time to conception was 3.73 months. Conclusion: Despite lower pregnancy rates compared with the broader literature, these outcomes are deemed acceptable, particularly for centers lacking facilities for more advanced surgical options. Therefore, macroscopic tubal reanastomosis through mini-laparotomy emerges as a feasible alternative for surgeons with limited experience in more intricate microsurgical techniques, providing a viable pathway to restoring fertility with reasonable success.

This study was conducted to evaluate the effects of epilepsy on pregnancy and delivery outcomes. It aimed to assess the relationship of seizure type, the presence of seizures during pregnancy, and the timing of the last seizure before conception on perinatal outcomes for pregnant women with epilepsy (WWE). The research included 300 participants, comprising 100 pregnant WWE and a control group of 200 healthy pregnant women. The study analyzed demographic and clinical data for all subjects. Perinatal outcomes were evaluated according to seizure type, seizure status during pregnancy, and the last seizure before pregnancy. The results showed a high rate of cesarean sections in the epilepsy group, at 71%. The number of babies born small for gestational age (SGA) was also significantly higher among WWE (p = 0.001). While there was no significant difference in most maternal and fetal outcomes between women with generalized and non-generalized seizures, the study identified pre-conception presence of seizures as a critical factor. Women who had experienced a seizure within the year before becoming pregnant had babies born at an earlier gestational week (p = 0.021) and with a lower birth weight (p = 0.018) compared to those whose last seizure was more than a year ago. Furthermore, 45% of the WWE had seizures during their pregnancy. The most important predictor of seizures during pregnancy is the presence of seizures before pregnancy. Presence of seizures during gestation is strongly associated with adverse perinatal outcomes, whereas the specific type of epilepsy is not.