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The Uncanny Valley hypothesis implies that people perceive a subjective border between human and robot faces. The robot–human border refers to the level of human-like features that distinguishes humans from robots. However, whether people’s perceived anthropomorphism and robot–human borders are consistent across different robot occupations remains to be explored. This study examined the robot–human border by analyzing the human photo proportion represented by the point of subjective equality in three image classification tasks. Stimulus images were generated by morphing a robot face photo and one each of four human photos in systematically changed proportions. Participants classified these morphed images in three different robot occupational conditions to explore the effect of changing robot jobs on the robot–human border. The results indicated that robot occupation and participant age and gender influenced people’s perceived anthropomorphism of robots. These can be explained by the implicit link between robot job and appearance, especially in a stereotyped context. The study suggests that giving an expected appearance to a robot may reproduce and strengthen a stereotype that associates a certain appearance with a certain job.

Over-the-counter medication electronic health records (OTC-EHRs) play a significant role in users’ self-medication practices. In this study, we consider the potential advantages of wearable smart devices in health management, along with the information processing capabilities of artificial intelligence (AI), and we propose a conceptual design for an AI-assisted wearable OTC-EHR system. Our objective was to systematically explore the relationship between eHealth literacy, users’ attitudes, and willingness to use the proposed system, as well as to discuss AI interventions. Internet users from China participated in an online survey examining eHealth literacy, subjective attitudes, and motivation to use this conceptual design. Descriptive statistical, correlation, difference, and regression analyses were conducted on 372 valid responses to test the research hypotheses. The results showed that the wearable-device-based OTC-EHR system with AI assistance was accepted by most responders and positively associated with eHealth literacy, which was, in turn, associated with decision-making preferences. This study suggests that AI may be perceived as an auxiliary tool for medication-related decision-making and is associated with the degree of eHealth literacy. Individuals with higher eHealth literacy are more likely to make autonomous decisions, whereas those with lower literacy will potentially rely more on AI support and professional guidance.

Trypophobia has attracted scientific attention in recent years. Few related studies have recruited participants using online methods, and even less is known about health communication in an environment where trypophobia was first widely discussed (i.e., the Internet). This study describes communication patterns in a Facebook group for trypophobia by detecting frequent topics, top contributors, and their discourses. We identified key commenters and performed word frequency analysis, word co-occurrence analysis, topic modeling, and content analysis. Impactful users posted and replied more often when discussing peer-reviewed science. Triggering content was actively removed by the group administrators. A wide variety of triggers not discussed in trypophobia-related literature were frequently mentioned. However, there was a lack of discussion on peer-reviewed treatments. The combination of a few expert and many supportive amateur gatekeepers willing to understand trypophobia, along with active monitoring by administrators, might contribute to in-group trust and the sharing of peer-reviewed science by top users of the trypophobia Facebook group.

To study the size-resolved characteristics of airborne bacterial community composition, diversity, and abundance, outdoor aerosol samples were analysed by 16S rRNA gene-targeted quantitative PCR and amplicon sequencing with Illumina MiSeq. The samples were collected using size-resolved samplers between August and October 2016, at a suburban site in Toyama City and an urban site in Yokohama City, Japan. The bacterial communities were found to be dominated by Actinobacteria, Firmicutes, and Proteobacteria. At the genus level, we found a high abundance of human skin-associated bacteria, such as Propionibacterium , Staphylococcus , and Corynebacterium , in the urban site. Whereas, a high abundance of bacteria associated with soil and plants, such as Methylobacterium and Sphingomonas , was observed in the suburban site. Furthermore, our data revealed a shift in the bacterial community structure, diversity, and abundance of total bacteria at a threshold of 1.1-µm diameter. Interestingly, we observed that Legionella spp., the causal agents of legionellosis in humans, were mainly detected in > 2.1 µm coarse particles. Our data indicate that local environmental factors including built environments could influence the outdoor airborne bacterial community at each site. These results provide a basis for understanding the size-resolved properties of bacterial community composition, diversity, and abundance in outdoor aerosol samples and their potential influence on human health.

Rice husk charcoal (RC) produced from the pyrolysis of rice husk (RH) can be one of the cost-effective biochars for use in rice-based farming systems. This study investigated changes in rice yield and soil carbon sequestration over three years of RC application to an Andosol paddy field. The treatments were RC application at 0.02, 0.2, and 2 kg m −2 (RC0.02, RC0.2, and RC2, respectively), RH application at 0.2 kg m −2 (RH0.2), and a control with no RC or RH application (CONT). The results showed that RC2 increased culm length by 4% and straw weight by 14% on average over the three years. These increases in plant growth coincided with a higher level of silicon uptake by the rice plants, although they did not significantly affect grain yield. The soil carbon content was progressively increased by RC2 over the three years, whereas it was not significantly affected by RC0.02 or RC0.2. A considerable amount (>72%) of the applied carbon with RC2 remained in the soil by taking account of its downward movement below the 10 cm layer of the paddy field after three consecutive years of RC application. We conclude that rice husk charcoal application to Andosol paddy fields is an effective option for increasing carbon sequestration. Furthermore, the increase in silicon uptake by rice plants suggests that rice husk charcoal can also be functioning as a silicon fertilizer.

Dots on natural backgrounds can elicit significant pupillary constrictions within the entire image phase associated with parasympathetic activation, suggesting disgust rather than fear. Although studies have reported that dots on faces elicit stronger disgust than dots on non-face backgrounds, it remains unclear whether dots on a face elicit stronger pupil constrictions than non-face backgrounds. Pupillometry was used while viewing dots on faces and compared with luminance- and spatial frequency-controlled images (dots on phase-scrambled faces) and luminance-controlled images (face only, phase-scrambled faces). Relative pupillary constrictions were elicited when dots were placed on faces and phase-scrambled faces; however, the response to dots on faces did not differ significantly from that to the control stimuli. Approximately 3–5 s after stimulus onset, pupillary responses to dots on faces recovered to baseline faster than those to dots on phase-scrambled faces with a larger pupil size. The initial pupillary constrictions observed are consistent with those in response to dots on natural backgrounds, suggesting that regardless of the background, dots may stimulate parasympathetic activation and elicit disgust rather than fear. The faster recovery from the pupil constriction and larger pupil size in the later phase may be caused by a dynamic balance between the sympathetic and parasympathetic neuronal activities.

Background Studies have shown that viewing a cluster of dots evokes feelings of discomfort in viewers and that the discomfort becomes especially strong when the dots are placed on background images of human skin. This phenomenon has been explained by the physical properties and spatial and semantic relationships between the dots and the background. However, it was not known whether the perceived, as well as the physical, spatial relationships contributes to the generation of discomfort. Methods We evoked illusory depth perception between black dots and the background face by drawing shadow-like gray dots around the black dots, while keeping the same black dots at the same positions, and examined whether illusory depth perception could increase or decrease discomfort. In each trial, participants viewed one of the following types of facial images: (a) face-only (face without dots), (b) a cluster of black dots on the face, (c) a cluster of gray dots on the face, and (d) a cluster of black dots and shadow-like gray dots on the face. After seeing each picture, they evaluated how much discomfort they felt from viewing the picture using a Likert scale and reported whether they perceived depth between the dots and the face. Results Participants felt discomfort toward all three types of faces with dots, that is, faces with black dots, gray dots, and both. However, interestingly, participants felt less discomfort when both black and gray dots were presented on the face than when only black dots were presented. The participants perceived depth between the black dots and the face in 85% of the trials with black dots and shadow-like gray dots, and there was a significant correlation between discomfort and frequency of depth perception. However, in the trials with black dots only and gray dots only, they perceived depth in only 18% and 27% of the trials, respectively, and the correlations between the frequencies of depth perception and discomfort were not significant. Conclusions Our results suggest that the perceived spatial relationship, such as attached vs. separate, as well as the physical spatial relationship, contribute to the generation of discomfort.

Most amputees experience phantom limb, whereby they feel that the amputated limb is still present. In some cases, these experiences include pain that can be alleviated by \"mirror therapy.\" Mirror therapy consists of superimposing a mirrored image of the moving intact limb onto the phantom limb. This therapy provides a closed loop between the motor command to the amputated limb and its predicted visual feedback. This loop is also involved in the sense of agency, a feeling of controlling one's own body. However, it is unclear how mirror therapy is related to the sense of agency over a phantom limb. Using mirror therapy, we investigated phantom limb pain and the senses of agency and ownership (i.e., a feeling of having one's own body) of the phantom limb. Nine upper-limb amputees, five of whom reported recent phantom limb pain, underwent a single 15-min trial of mirror therapy. Before and after the trial, the participants completed a questionnaire regarding agency, ownership, and pain related to their phantom limb. They reported that the sense of agency over the phantom limb increased following the mirror therapy trial, while the ownership slightly increased but not as much as did the agency. The reported pain did not change; that is, it was comparably mild before and after the trial. These results suggest that short-term mirror therapy can, at least transiently, selectively enhance the sense of agency over a phantom limb, but may not alleviate phantom limb pain.

Visual stimuli, such as stripes and texts, can induce \"visual discomfort\" including perceptual and somatic symptoms. Individuals reporting high levels of visual discomfort might experience migraine headache and may have reduced reading efficiency due to visual perceptual difficulties. This study aimed to develop and validate the Japanese version of the Visual Discomfort Scale, which measures proneness to visual discomfort. In Survey 1, 428 adults completed the Japanese version and a questionnaire assessing migraine morbidity. Rasch analysis revealed that the Japanese version is a unidimensional scale with a high amount of unexplained variance due to random noise rather than another dimension, and has high person and item reliabilities. Participants with migraine exhibited high scores in the Japanese version, indicating the construct validity of the scale. Survey 2 with 118 adults revealed a strong test-retest correlation for the Japanese version, indicating the stability of the scale. The Japanese version of the Visual Discomfort Scale is a sufficiently reliable and valid scale for assessing visual discomfort, although its unidimensionality leaves room for further improvements.

Since the enactment of the revised Pharmaceutical Affairs Act in Japan in 2009, self-medication practices have increased in the country. However, studies report that consumers pay little attention to the medication facts and risks indicated on the packages of over-the-counter (OTC) medicines, which could be a potential risk. Since the COVID-19 pandemic, the digital transformation of purchasing OTC medicines has progressed. As an appropriate design for the digital transformation is likely to improve consumers' literacy and them obtaining medical information, this study systematically examines Japanese consumers' attitudes toward the digital transformation of OTC medicine purchase behavior and its correlation to eHealth literacy, exploring an appropriate digital experience design in purchasing OTC medicine. Participants from the Greater Tokyo Area of Japan participated in an online survey. Consumers' current behavior and preferences in accessing OTC medicine, receiving medication guidance, and obtaining medical information were examined. eHealth literacy was assessed using the J-eHEALS. Descriptive statistics, text mining, and thematic analysis were conducted to answer research questions. Over 89% of the respondents who had experience in purchasing OTC medicines preferred local pharmacies or stores rather than online purchasing,  < 0.001. Obtaining medicine guidance in pharmacies or stores was the main preference over other approaches,  < 0.001. Furthermore, most of the participants accepted selecting medicine on shelves and digital screens in-store. However, they were accustomed to using smartphones to obtain additional information at the pharmacy or drug store,  < 0.001; this behavior was positively correlated with eHealth literacy,  < 0.001. Japanese consumers are seeking a combination of conventional and digital behaviors for purchasing OTC medicine rather than opting for a particular method. Most consumers prefer purchasing and receiving instructions in-store while searching for additional decision-making information online. eHealth literacy is positively associated with digital behaviors of OTC medicine information acquisition but less associated with medicine purchases and selections. The hybrid digital experience design may enhance the OTC medicine purchase experience and reduce potential risks by providing appropriate information.