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Aims To determine adverse effects of ventrogluteal intramuscular injections versus dorsogluteal intramuscular injections. Design A systematic review and meta‐analysis. Methods MEDLINE, EMBASE, CINHAL, CENTRAL, LILACS(BVS), BDENF (BVS), WoS, IRCTP(WHO), ClinicalsTrials.gov and PROSPERO databases were searched with no restriction on year or language. Preferred Reporting items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines were followed. Results A total of 1429 participants from 17 studies were included. The meta‐analysis found that ventrogluteal injection site had significant relation to lower pain in 9 studies (SMD = −0.63, 95% CI = −0.87, −0.39), bleeding in 4 studies (SMD = −3.46, 95% CI = −6.07, –0.86) and hematoma in 2 studies; after 48 h (SMD = −0.25, 95% CI = −0.39, −0.11), and after 72 h (SMD = −0.16, 95% CI = −0.26, –0.06), if it was compared with dorsogluteal site injection. No differences were found when comparing the possibility of intramuscular injections given into de subcutaneous tissue. In three studies, ventrogluteal site did not significantly reduce the risk of subcutaneous injection (OR 0,62, 95% CI = 0.16, 2.41).

Uterine sarcomas are very infrequent and heterogeneous entities. Due to its rarity, pathological diagnosis, surgical management, and systemic treatment are challenging. Treatment decision process in these tumors should be taken in a multidisciplinary tumor board. Available evidence is low and, in many cases, based on case series or clinical trials in which these tumors have been included with other soft tissue sarcoma. In these guidelines, we have tried to summarize the most relevant evidence in the diagnosis, staging, pathological disparities, surgical management, systemic treatment, and follow-up of uterine sarcomas.

Background In modern times, horses are utilized not only for labour and transportation purposes but also for recreational activities such as competition and pleasure riding. In these various pursuits, the role of vision plays a crucial role. Electroretinography is the most used test to diagnose diseases of the retinal outer segment. There is a wide variety of devices to perform the electroretinography differing one from each other in the corneal electrode and the light stimulation. The Koijman electrode has been tested in dogs but not in horses. The main purpose of this study was to compare electroretinography parameters from horses sedated with detomidine alone or in combination with butorphanol, during a standardized protocol using the Koijman electrode and RETI-port® system. Seven mares were allocated to the detomidine and detomidine plus butorphanol group in a randomised, controlled, crossover study. Friedman and Willcoxon-signed ranked tests were used to compare the electroretinogram parameters. A Student’s t-test was used to compare differences in the number of artefacts to valid values ratio obtained under both sedation protocols. Results Dark adaptation peaked after 16 min under scotopic conditions in both groups. No significant differences in electroretinogram parameters between groups were observed. During the mixed rod and cone response evaluation under scotopic conditions, all mares made a movement of the head resulting in a high number of artefacts. The detomidine plus butorphanol group showed a non-significant tendency to have fewer artefacts and a longer duration of sedation compared to the detomidine group. Conclusions Detomidine alone or combined with butorphanol may be suitable to use Koijman electrode and the RETI-port® to perform a standardized long protocol in horses with some adaptations.

This study analyzed the tasks associated with measures of central tendency proposed to Chilean students from 5th to 8th year of basic education. For this purpose, the activities involving mean, median, and/or mode were identified through the revision of two series of textbooks (16). The units of analysis were (1) type of measure, (2) task, (3) context, (4) support, and (5) cognitive skill. The main findings allowed us to indicate that the texts are aligned with the curricular guidelines, with tasks mostly associated with mean and mode, prioritizing calculation. Additionally, the tasks lack a context that gives meaning to the data. The support in which the data is presented is written and tabular. Finally, regarding the type of cognitive skills with the greatest presence in the textbooks, these are at a basic level.

Zinc oxide nanoparticles (ZnO NPs) are prepared by sol–gel process, using both polyethylene glycol (PEG-400) as surfactant and propyltrimethoxysilane (PTMS) as capping agent. Surface modification is performed in situ procedure. The physical parameters such as strain and stress values are calculated via the Williamson–Hall plot (W&H) assuming a uniform deformation model (UDM) and uniform stress deformation model, and by the size and strain plot method (SSP). The results show that the crystallite size estimated from Scherrer’s formula, (W&H), (UDM), (SSP) and the particle size estimated from DSL are inter-correlated, which confirm the small size and the isotropic nature of our ZnO NPs. The FTIR spectroscopy illustrates that PEG-400 and PTMS could be adsorbed at the ZnO NPs surface. The distinct emission peak in the blue band is located at 490 nm and E 2 (high) mode is situated at 436 cm −1 . Both results confirm the oxygen deficiency in the ZnO NPs.

We use a tunable commercial liquid-crystal device tuned to a quarter-wave retardance to study the generation and dynamics of different types of hybrid vector beams. The standard situation where the q-plate is illuminated by a Gaussian beam is compared with other cases where the input beam is a vortex or a pure vector beam. As a result, standard hybrid vector beams but also petal-like hybrid vector beams are generated. These beams are analyzed in the near field and compared with the far field distribution, where their hybrid nature is observed as a transformation of the intensity and polarization patterns. Analytical calculations and numerical results confirm the experiments. We include an approach that provides an intuitive physical explanation of the polarization patterns in terms of mode superpositions and their transformation upon propagation based on their different Gouy phase. The tunable q-plate device presents worthy advantages, since it allows a compact and efficient generation of pure and hybrid vector beams to study these effects.

Background: this study aimed to describe and understand the experiences and health needs of women irregular migrants during emergency care provision upon arrival in Spain by small boat. Methods: a qualitative study based on Gadamer’s phenomenology was used. The data collection included 13 in-depth interviews with women irregular migrants and 10 in-depth interviews with key informants. The study took place in the Spanish Red Cross’ facilities between February 2017 and April 2018. Results: two main themes emerged from the data analysis: the need for emergency care focused on women irregular migrants with the sub-themes ‘Women irregular migrants as objects of sexual exploitation’ and ‘The mother-child dyad as the axis in human trafficking’; and developing an emergency care gender policy for women irregular migrants, with the subthemes ‘Healthcare in a police-controlled setting: detecting weaknesses’ and ‘Promoting screening and safety protocols focused on women irregular migrants’. Conclusions: women irregular migrants who arrive in Spain by small boat have specific needs and healthcare problems. Due to strict safety conditions during emergency care provision, rape and human trafficking can go unnoticed. Implications: interdisciplinary care protocols and new health policies that have a gender perspective are needed to improve the emergency care provided to women irregular migrants.

In order to control the spread of COVID-19, people must adopt preventive behaviours that can affect their day-to-day life. People’s self-efficacy to adopt preventive behaviours to avoid COVID-19 contagion and spread should be studied. The aim of this study was to develop and psychometrically test the COVID-19 prevention, detection, and home-management self-efficacy scale (COVID-19-SES). We conducted an observational cross-sectional study. Six-hundred and seventy-eight people participated in the study. Data were collected between March and May 2020. The COVID-19-SES’ validity (content, criterion, and construct), reliability (internal consistency and test-retest reliability), and legibility were studied. The COVID-19-SES’ reliability was high (Cronbach’s alpha = 0.906; intraclass correlation coefficient = 0.754). The COVID-19-SES showed good content validity (scale’s content validity index = 0.92) and good criterion validity when the participants’ results on the COVID-19-SES were compared to their general self-efficacy (r = 0.38; p < 0.001). Construct validity analysis revealed that the COVID-19-SES’ three-factor structure explained 52.12% of the variance found and it was congruent with the World Health Organisation’s recommendations to prevent COVID-19 contagion and spread. Legibility analysis showed that the COVID-19-SES is easy to read and understand by laypeople. The COVID-19-SES is a psychometrically robust instrument that allows for a valid and reliable assessment of people’s self-efficacy in preventing, detecting symptoms, and home-managing COVID-19.

In this study, we investigated the microbial community (bacteria and fungi) colonising an oil painting on canvas, which showed visible signs of biodeterioration. A combined strategy, comprising culture-dependent and -independent techniques, was selected. The results derived from the two techniques were disparate. Most of the isolated bacterial strains belonged to related species of the phylum Firmicutes, as Bacillus sp. and Paenisporosarcina sp., whereas the majority of the non-cultivable members of the bacterial community were shown to be related to species of the phylum Proteobacteria, as Stenotrophomonas sp. Fungal communities also showed discrepancies: the isolated fungal strains belonged to different genera of the order Eurotiales, as Penicillium and Eurotium, and the non-cultivable belonged to species of the order Pleosporales and Saccharomycetales. The cultivable microorganisms, which exhibited enzymatic activities related to the deterioration processes, were selected to evaluate their biodeteriorative potential on canvas paintings; namely Arthrobacter sp. as the representative bacterium and Penicillium sp. as the representative fungus. With this aim, a sample taken from the painting studied in this work was examined to determine the stratigraphic sequence of its cross-section. From this information, \"mock paintings,\" simulating the structure of the original painting, were prepared, inoculated with the selected bacterial and fungal strains, and subsequently examined by micro-Fourier Transform Infrared spectroscopy, in order to determine their potential susceptibility to microbial degradation. The FTIR-spectra revealed that neither Arthrobacter sp. nor Penicillium sp. alone, were able to induce chemical changes on the various materials used to prepare \"mock paintings.\" Only when inoculated together, could a synergistic effect on the FTIR-spectra be observed, in the form of a variation in band position on the spectrum.

The authors gratefully acknowledge the financial support from the Spanish Ministry of Economy and Competitiveness (MINECO) and the CCEI-University of Cantabria for the Ramón y Cajal programme (RYC-2011-08550) and MINECO for the project CTQ2012-31229. Joaquín Coronas (Universidad de Zaragoza) is also gratefully acknowledged for the use of DSC equipment and fruitful discussions.