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\"Published just months after the end of the 1948 war that followed the establishment of the state of Israel, Khirbet Khizeh was an immediate sensation. Since then, the book has continued to challenge and disturb, and has even made it into the school curriculum in Israel.\"--Back cover.

As ocean general circulation models (OGCMs) move into the petascale age, where the output of single simulations exceeds petabytes of storage space, tools to analyse the output of these models will need to scale up too. Lagrangian ocean analysis, where virtual particles are tracked through hydrodynamic fields, is an increasingly popular way to analyse OGCM output, by mapping pathways and connectivity of biotic and abiotic particulates. However, the current software stack of Lagrangian ocean analysis codes is not dynamic enough to cope with the increasing complexity, scale and need for customization of use-cases. Furthermore, most community codes are developed for stand-alone use, making it a nontrivial task to integrate virtual particles at runtime of the OGCM. Here, we introduce the new Parcels code, which was designed from the ground up to be sufficiently scalable to cope with petascale computing. We highlight its API design that combines flexibility and customization with the ability to optimize for HPC workflows, following the paradigm of domain-specific languages. Parcels is primarily written in Python, utilizing the wide range of tools available in the scientific Python ecosystem, while generating low-level C code and using just-in-time compilation for performance-critical computation. We show a worked-out example of its API, and validate the accuracy of the code against seven idealized test cases. This version 0.9 of Parcels is focused on laying out the API, with future work concentrating on support for curvilinear grids, optimization, efficiency and at-runtime coupling with OGCMs.

InMeanings of Maple, Michael A. Lange provides a cultural analysis of maple syrup making, known in Vermont as sugaring, to illustrate how maple syrup as both process and product is an aspect of cultural identity.Readers will go deep into a Vermont sugar bush and its web of plastic tubes, mainline valves, and collection tanks. They will visit sugarhouses crammed with gas evaporators and reverse-osmosis machines. And they will witness encounters between sugar makers and the tourists eager to invest Vermont with mythological fantasies of rural simplicity.So much more than a commodity study,Meanings of Mapleframes a new approach for evaluating the broader implications of iconic foodways, and it will animate conversations in food studies for years to come.

Background The German Health Interview and Examination Survey for Adults (DEGS) is part of the recently established national health monitoring conducted by the Robert Koch Institute. DEGS combines a nationally representative periodic health survey and a longitudinal study based on follow-up of survey participants. Funding is provided by the German Ministry of Health and supplemented for specific research topics from other sources. Methods/design The first DEGS wave of data collection (DEGS1) extended from November 2008 to December 2011. Overall, 8152 men and women participated. Of these, 3959 persons already participated in the German National Health Interview and Examination Survey 1998 (GNHIES98) at which time they were 18–79 years of age. Another 4193 persons 18–79 years of age were recruited for DEGS1 in 2008–2011 based on two-stage stratified random sampling from local population registries. Health data and context variables were collected using standardized computer assisted personal interviews, self-administered questionnaires, and standardized measurements and tests. In order to keep survey results representative for the population aged 18–79 years, results will be weighted by survey-specific weighting factors considering sampling and drop-out probabilities as well as deviations between the design-weighted net sample and German population statistics 2010. Discussion DEGS aims to establish a nationally representative data base on health of adults in Germany. This health data platform will be used for continuous health reporting and health care research. The results will help to support health policy planning and evaluation. Repeated cross-sectional surveys will permit analyses of time trends in morbidity, functional capacity levels, disability, and health risks and resources. Follow-up of study participants will provide the opportunity to study trajectories of health and disability. A special focus lies on chronic diseases including asthma, allergies, cardiovascular conditions, diabetes mellitus, and musculoskeletal diseases. Other core topics include vaccine-preventable diseases and immunization status, nutritional deficiencies, health in older age, and the association between health-related behavior and mental health.

Background Longitudinal studies are essential for understanding health trajectories and determinants over time. Successfully re-engaging and monitoring participants at key stages such as the transition from adolescence to adulthood is crucial. This stage of life is characterized by many changes and challenges and is considered critical for the manifestation of mental health problems. This study addresses challenges of contacting, re-activation and comparability of individuals in transition to adulthood with the initial population-based sample last contacted up to 9 years ago. Methods In 2024, former participants of the “German Health Interview and Examination Survey for Children and Adolescents” (KiGGS) aged 16–25 years were invited to register in the new online panel infrastructure “Health in Germany” and participate in the “Study on Mental Health in Emerging Adulthood” (JEPSY) via a push-to-online panel approach. Logistic regression models identified predictors of registration and study participation. Weighting adjustments were applied to analyse and correct for selective participation. To assess potential selection bias, life satisfaction of JEPSY participants was benchmarked against a representative sample. Results Among 11,737 invitees, 4,451 (37.9%) registered, and among these, 3,063 (68.8%) completed the JEPSY survey. For participants aged 11 + years, higher probabilities for registration and participation were evident for females (OR = 2.61 [95% CI: 2.37–2.88]); OR = 2.85, [2.56–3.18]), individuals with higher occupational (OR = 1.08, [1.04–1.13]; OR = 1.06, [1.01–1.11]) or educational status (OR = 1.13, [1.08–1.17]; OR = 1.13, [1.08–1.17]). Individuals with higher emotional problems were less likely to register (OR = 0.98, [0.97–0.99]) and participate (OR = 0.98, [0.97–0.99]). Weighting adjustments reduced biases but increased statistical variance. Benchmarking life satisfaction revealed no significant differences between JEPSY participants and their representative counterparts. Conclusions This study demonstrated the feasibility of re-activating former participants and integrating them into a modern online panel. While re-activation was successful for a substantial proportion of invitees, specific challenges (e.g., selective re-participation) remain. The findings provide insights for refining re-contact and retention strategies to improve representativeness and quality of longitudinal mental health research, ultimately enabling more accurate monitoring of health trajectories and their determinants over time.

Cemeteries give evidence for a continuous change in sepulchral culture and provide insights into the application of characteristical rock materials used for tombstones during different times. Four selected cemeteries in Dresden (the Eliasfriedhof/Elias Cemetery, the Trinitatisfriedhof/Trinity Cemetery, the Johannisfriedhof/Johannis Cemetery, and the Städtischer Urnenhain/Municipal Urn Grove), which are of considerable cultural and historical importance, have been investigated within an ongoing mapping project. First results of this project focussing on the tombstone inventory of the mentioned graveyards and thus the use of building and decoration stones therein between 1680 and 1945 are presented in this paper. It can be demonstrated that the choice, variety, and application of rock material depends on the infrastructure and transport possibilities, but is also strongly influenced by sepulchral cultural trends and the prevailing zeitgeist. Until the middle of the 19th century, nearly solely Elbe sandstone (from the area of the Elbsandsteingebirge/Elbe sandstone mountains), that was transported on the Elbe river by ship, is found as rock material for tombstones in Dresden cemeteries. Rapid construction and development of the railway network starting around 1840 improved the availability, at first, of regional rock material (e.g., from the Lausitz/Lusatia) and, later on, from about 1880, of national and international—especially European—rock material (e.g., from Franken/Franconia, France, Scandinavia). Furthermore, the Friedhofsreformbewegung/cemetery reform movement at the beginning of the 20th century, with its significant effect on the selection of rock types used for tombstones, marks another historical breakthrough.

Many comprehensive cancer centers incorporate tumor documentation software supplying structured information from the associated centers' oncology patients for internal and external audit purposes. However, much of the documentation data included in these systems often remain unused and unknown by most of the clinicians at the sites. To improve access to such data for analytical purposes, a prerollout of an analysis layer based on the business intelligence software QlikView was implemented. This software allows for the real-time analysis and inspection of oncology-related data. The system is meant to increase access to the data while simultaneously providing tools for user-friendly real-time analytics. The system combines in-memory capabilities (based on QlikView software) with innovative techniques that compress the complexity of the data, consequently improving its readability as well as its accessibility for designated end users. Aside from the technical and conceptual components, the software's implementation necessitated a complex system of permission and governance. A continuously running system including daily updates with a user-friendly Web interface and real-time usage was established. This paper introduces its main components and major design ideas. A commented video summarizing and presenting the work can be found within the Multimedia Appendix. The system has been well-received by a focus group of physicians within an initial prerollout. Aside from improving data transparency, the system's main benefits are its quality and process control capabilities, knowledge discovery, and hypothesis generation. Limitations such as run time, governance, or misinterpretation of data are considered.

Culturing cells as adherent monolayers is a common approach in cell biology. For cell culture experiments to yield reliable results it is important to replicate in vivo conditions as faithfully as possible. Increasingly, researchers appreciate the importance of oxygen in cell physiology and the corresponding need to maintain physiologically relevant oxygen levels during experiments. However, although oxygen levels are sometimes monitored over the course of an experiment, this is virtually always in the incubator gas phase and not in the media bathing cells. When incubator oxygen levels are set to a physiologically appropriate level, typically 2–6%, the pericellular oxygen levels experienced by cells may be substantially lower, particularly under conditions where cells are respiring rapidly. We have developed a simple approach to prevent this problem. ‘Hypoxio’ is a software application that uses real time measurements of pericellular oxygen to coordinate media mixing via a tilt table. Hypoxio allows the user to set a threshold below which it initiates a mixing cycle of user-adjustable duration to abolish standing gradients associated with pericellular hypoxia. Here we describe Hypoxio, demonstrate its efficacy, and direct the reader to our GitHub site for downloadabale software and a description of hardware.

Students in the fine and performing arts who begin their studies at community colleges often achieve the strongest educational and career outcomes when they are able to complete a bachelor’s degree. In Wyoming, this requires transferring from one of the state’s community colleges to the University of Wyoming or another institution of higher education that offers bachelor’s degrees. While research on rural transfer pathways is growing, limited scholarly attention has been given to transfer experiences specifically within the fine and performing arts. This phenomenological study examined the perspectives of faculty and administrators at Wyoming community colleges and the University of Wyoming who support student transfer in the fine and performing arts. The central research question guiding the inquiry was: What is your experience with the transfer process from Wyoming community colleges to the University of Wyoming in the fine and performing arts?Findings revealed themes related to communication and capacity challenges, the importance of high-quality advising, structural barriers, faculty ownership of transfer processes, and student readiness. Recommendations include building institutional capacity for transfer support, establishing shared accountability mechanisms, creating multiple program entry points to accommodate varied student preparation, and exploring the role of community college bachelor’s degrees in addressing transfer barriers.