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result(s) for
"Lee, Jo Ann"
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Asymptomatic spread of huanglongbing and implications for disease control
by
Cecile J. Robertson
,
William O. Dawson
,
Burton H. Singer
in
adults
,
Animals
,
asymptomatic huanglongbing
2015
Huanglongbing (HLB) is a bacterial infection of citrus trees transmitted by the Asian citrus psyllid Diaphorina citri . Mitigation of HLB has focused on spraying of insecticides to reduce the psyllid population and removal of trees when they first show symptoms of the disease. These interventions have been only marginally effective, because symptoms of HLB do not appear on leaves for months to years after initial infection. Limited knowledge about disease spread during the asymptomatic phase is exemplified by the heretofore unknown length of time from initial infection of newly developing cluster of young leaves, called flush, by adult psyllids until the flush become infectious. We present experimental evidence showing that young flush become infectious within 15 d after receiving an inoculum of Candidatus Liberibacter asiaticus (bacteria). Using this critical fact, we specify a microsimulation model of asymptomatic disease spread and intensity in a grove of citrus trees. We apply a range of psyllid introduction scenarios to show that entire groves can become infected with up to 12,000 psyllids per tree in less than 1 y, before most of the trees show any symptoms. We also show that intervention strategies that reduce the psyllid population by 75% during the flushing periods can delay infection of a full grove, and thereby reduce the amount of insecticide used throughout a year. This result implies that psyllid surveillance and control, using a variety of recently available technologies, should be used from the initial detection of invasion and throughout the asymptomatic period.
Significance Huanglongbing (HLB) is a vector-transmitted bacterial infection of citrus trees that poses a major threat to the citrus industry in Florida, Texas, and California. Current control strategies that focus on the vector, the Asian citrus psyllid Diaphorina citri , are usually initiated when the trees become symptomatic, anywhere from 10 mo to several years after initial infection. We show, experimentally, that newly infected young leaves can become infectious within 10â15 d after receiving an inoculum of bacteria from an adult psyllid. We then show by microsimulation of the asymptomatic spread of HLB through a grove under different invasion scenarios and control strategies that reduction of up to 75% of adult psyllids and nymphs can enhance citrus production.
Journal Article
What Factors Influence Long-term Survivorship After Hip Arthroscopy?
by
Jarrett, Bryan T.
,
McCarthy, Joseph C.
,
Bragdon, Charles R.
in
Acetabulum - pathology
,
Adolescent
,
Adult
2011
Background
Hip arthroscopy is an evolving procedure. One small study suggested that a low modified Harris hip score and arthritis at the time of surgery were predictors of poor prognosis.
Questions/purposes
We therefore intended to confirm those findings with a large patient cohort to (1) determine the long-term nonarthritic hip score; (2) determine survivorship; (3) identify risk factors that increase the likelihood of THA; and (4) use those factors to create a usable risk assessment algorithm.
Patients and Methods
We retrospectively reviewed 324 patients (340 hips) who underwent arthroscopy for pain and/or catching. Of these, 106 patients (111 hips or 33%) had a minimum followup of 10 years (mean, 13 years; range, 10–20 years). The average age was 39 years (± 13) with 47 men and 59 women. We recorded patient age, gender, acetabular and femoral Outerbridge grade at surgery, and the presence of a labral tear. Followup consisted of a nonarthritic hip score or the date of a subsequent THA. We determined survivorship with the end point of THA for the acetabular and femoral Outerbridge grades.
Results
Overall survivorship among the 111 hips was 63% at 10 years. The average nonarthritic hip score for non-THA patients was 87.3 (± 12.1). Survivorship was greater for acetabular and femoral Outerbridge grades normal through II. Age at arthroscopy and Outerbridge grades independently predicted eventual THA. Gender and the presence of a labral tear did not influence long-term survivorship.
Conclusions
The long-term survivorship of labral tears with low-grade cartilage damage indicates hip arthroscopy is reasonable for treating labral tears.
Level of Evidence
Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Journal Article
The Role of Arthroscopy in Evaluation of Painful Hip Arthroplasty
2009
Unexplained pain after hip arthroplasty is frustrating for patients and surgeons. We describe the use of hip arthroscopy in management of the painful hip arthroplasty, critically evaluate the outcomes of these patients, and refine indications for hip arthroscopy in this setting. We retrospectively reviewed 14 patients (16 hips) who underwent hip arthroscopy after joint replacement. One patient had suspected septic arthritis despite negative aspiration and one had known septic arthritis but was not a candidate for open arthrotomy; two had intraarticular migration of hardware. The remaining 10 patients (11 hips) had persistent pain despite negative diagnostic studies. The two patients (two hips) with infection were successfully treated with arthroscopic lavage and débridement plus intravenous antibiotics. Intraarticular metal fragments and a loose acetabular screw were successfully removed in two patients (three hips). Findings in the remaining 11 hips included a loose acetabular component (one); corrosion at the head-neck junction of a metal-on-metal articulation (one); soft tissue-scar impingement at the head/cup interface (four); synovitis with associated scar tissue (four); and capsular scarring with adhesions (one). Arthroscopy represented a successful treatment or directly led to a successful treatment in 12 of 16 hips. We observed no complications as a result of the arthroscopy. Arthroscopy may be of value in selected patients undergoing hip arthroplasty with unexplained pain after an inconclusive standard workup.
Level of Evidence:
Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
Journal Article
Assessing Homelessness and Incarceration Among Youth Aging Out of Foster Care, by Type of Disability
2023
Youth in foster care are at greater risk of incarceration and homelessness as they age out of care and transition to adulthood. Prior studies have shown that multiple placements, childhood trauma, race and ethnicity, and educational attainment are associated with these adverse outcomes. However, few studies have examined the prevalence and risk factors of incarceration and homelessness among youth in foster care with disabilities as they age out and transition into adulthood. Using data from the 2014 cohort of the National Youth in Transition Database (NYTD) and Adoption and Foster Care Analysis Reporting System (AFCARS), this study examines the prevalence of incarceration and homelessness by disability type at age 17, and how risk factors are related to incarceration and homelessness at ages 19 and 21. Findings show that youth in foster care with emotional disabilities are more likely to experience homelessness and incarceration, but this association was not robust in multivariate models. On the other hand, those with a physical or intellectual/developmental disability have lower odds of homelessness. Employment and school enrollment are associated with a lower risk of homelessness and incarceration, regardless of disability type. These results suggest that disaggregating youth in foster care by type of disability is necessary to provide specific recommendations to improve and target resources and supports for these vulnerable youth as they age out of foster care and transition to adulthood.
Journal Article
A Mathematic Model That Describes Modes of MdSGHV Transmission within House Fly Populations
2013
In this paper it is proposed that one potential component by which the Musca domestica salivary gland hypertrophy virus (MdSGHV) infects individual flies is through cuticular damage. Breaks in the cuticle allow entry of the virus into the hemocoel causing the infection. Male flies typically have a higher rate of infection and a higher rate of cuticular damage than females. A model for the transmission of MdSGHV was formulated assuming several potential and recognized means of transmission. The model yields results that are in agreement with field data that measured the infection rate in house flies on dairy farms in Florida. The results from this model indicate that MdSGHV will be maintained at a stable rate within house fly populations and support the future use of MdSGHV as a birth control agent in house fly management.
Journal Article
Proximally Coated Beaded Stem at Minimum 5-Year Follow-up
by
Naughton, Marybeth
,
McCarthy, Joseph C.
,
Lee, Jo-ann
in
Adult
,
Aged
,
Arthroplasty, Replacement, Hip - instrumentation
2008
This study examines fixation and bone preservation in a proximally coated circumferentially beaded femoral stem at minimum 5-year follow-up.
This multicenter, prospective study, examines a consecutive series of 153 primary uncemented total hip arthroplasties in 143 patients. Each patient was evaluated for stem fixation, bony response and complication rates. There were 94 men and 59 women. Average patient age was 59 years (range, 28–79 years). Clinical and radiographical evaluations were conducted preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, 2 years, and 5 years.
Radiographic results at minimum 5 year follow-up showed 98.5% are bone ingrown and stable by Engh criteria. Endosteal condensation was present in zone 1 in 82% (106 hips), 88% (112 hips) in zone 7, 74% (86 hips) in zone 14, and 67 % (77 hips) in zone 8. The comparison group had no radiographic loosenings or mechanical failures. There was one septic failure. There has been one revision for subsidence 5 days postoperative in a patient with DORR C bone and osteopenia. One additional patient required an open reduction and internal fixation of a subtrochanteric fracture. The open reduction and internal fixation stem is fibrous stable with a 4-mm lucency in zone 1, and 1 additional loose stem is scheduled to be revised. Distal pedestals were present in 21 cases (16%), 8 of which showed complete bridging.
At minimum 5-year follow-up, this femoral stem has demonstrated reliable bone ingrowth, no distal osteolysis, and proximal bone preservation. The proximal 3-dimensional coating has facilitated bone accretion, as manifested by cancellous condensation in 88%.
Figure:
Radiograph of an ingrown femoral stem at 5-year follow-up showing endosteal condensation in zones 1, 2, and 7.
Journal Article
Effects of Formal and Informal Deviant Labels in Adolescence on Crime in Adulthood
2017
The study reported in this article used labeling theory to examine the relationship between multiple labels in adolescence and self-reported criminal behavior in adulthood. This study used childhood, adolescent, and adult interviews (N = 357) from the Lehigh Longitudinal Study, which followed a high-risk community sample of individuals recruited from child welfare caseloads and other group settings in Pennsylvania. Structural equation modeling was used to estimate the effects of three measures of labeling (formal legal system involvement, false stops by the police, and reflected parental perceptions) on crime in adulthood. Gender differences also were examined. Reflected parental perceptions of adolescents as deviant were significantly associated with criminal behaviors in adulthood, but both legal system labels (that is, formal legal system involvement and false stops by the police) were not. There were no gender differences in the effect of labeling on later criminal behaviors.
Journal Article